Clean Implicit 3D Structure From Noisy 2D STEM Images

Hannah Kniesel, Timo Ropinski, Tim Bergner, Kavitha Shaga Devan, Clarissa Read, Paul Walther, Tobias Ritschel, Pedro Hermosilla; Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2022, pp. 20762-20772

Abstract


Scanning Transmission Electron Microscopes (STEMs) acquire 2D images of a 3D sample on the scale of individual cell components. Unfortunately, these 2D images can be too noisy to be fused into a useful 3D structure and facilitating good denoisers is challenging due to the lack of clean-noisy pairs. Additionally, representing detailed 3D structure can be difficult even for clean data when using regular 3D grids. Addressing these two limitations, we suggest a differentiable image formation model for STEM, allowing to learn a joint model of 2D sensor noise in STEM together with an implicit 3D model. We show, that the combination of these models are able to successfully disentangle 3D signal and noise without supervision and outperform at the same time several baselines on synthetic and real data.

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[bibtex]
@InProceedings{Kniesel_2022_CVPR, author = {Kniesel, Hannah and Ropinski, Timo and Bergner, Tim and Devan, Kavitha Shaga and Read, Clarissa and Walther, Paul and Ritschel, Tobias and Hermosilla, Pedro}, title = {Clean Implicit 3D Structure From Noisy 2D STEM Images}, booktitle = {Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)}, month = {June}, year = {2022}, pages = {20762-20772} }