prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Basal, UTD:01992912-611F-4A48-8570-B062CBCCAF7@. Final Pathologic Diagnosis: A. Left axilla sentinel lymph nodes, dissection: No tumor (0/3). B. Right medial breast, excision: 1. No tumor. 2. Usual ductal hyperplasia, sclerosing adenosis and calcifications. C. Right breast, partial mastectomy: 1. Invasive ductal carcinoma, 2.2 cm, grade 3; see comment. 2. Ductal carcinoma in situ, high nuclear grade with necrosis; see comment. Note: Breast Tumor Synoptic Comment. - Laterality: Right. - Invasive tumor type: Invasive ductal carcinoma. - Invasive tumor size: 2.2 cm. - Invasive tumor grade (modified Bloom-Richardson): Nuclear grade: 3 points. Mitotic count: 3 points. Tubule/papilla formation: 3 points. Total points and overall grade = 9 points = grade 3. - Lymphatic-vascular invasion: None. - Skin/nipple: Not sampled. - Margins for invasive tumor: Negative. - Deep margin: Negative; (tumor is <0.1 cm away, on slide C7). - Medial margin: Negative; (tumor is at least 0.8 cm away). - Lateral margin: Negative; (tumor is at least 2.4 cm away). - Anterior/superior margin: Negative; (tumor is 0.3 cm away, on slide C5). - Anterior/inferior margin: Negative; (tumor is 0.3 cm away, on slide C3). Ductal carcinoma in situ (DCIS): Comedo and solid. - Ductal carcinoma in situ size: DCIS present admixed with invasive cancer. Ductal carcinoma in situ nuclear grade: High grade. Working Draft. - Necrosis in DCIS: Present. Microcalcifications: Present in DCIS and benign ducts. Resection margins for ductal carcinoma in situ: Negative. - Deep margin: Negative; (tumor is 1.5 cm away, on slide C7). - Medial margin: Negative. - Lateral margin: Negative. - Anterior/superior margin: Negative; (tumor is 0.6 cm away, on slide C7). - Anterior/inferior margin: Negative. - Lymph node status: Negative. - Number of positive lymph nodes: 0. - Total number sampled: 3. - AJCC/UICC stage: pT2NOMX. Select slides (C2, C3, C4) were also reviewed by Dr. who concurs with the diagnosis. Immunostains for ER/PR and Her2 neu will be performed the results reported in an addendum. All margins were oriented, inked and examined microscopically. Intraoperative Consult Diagnosis. FS1 (A) Right axilla, sentinel lymph node #1, biopsy: Three lymph nodes, no carcinoma. (Dr. FS2 (B) Right medial fibrosis, rule out carcinoma, biopsy: Fibrocystic change, calcification, no tumor. (Dr. Clinical History. The patient is a. year-old woman with a history of right breast adenocarcinoma diagnosed by fine. needle aspiration. She now undergoes right breast partial mastectomy and right sentinel lymph node. biopsy. Gross Description. The specimen is received fresh in three parts, each labeled with the patient's name and unit number. Part A, additionally labeled IF. ," consists of a single soft irregular piece of red-yellow. fibrofatty tissue measuring 3 x 2 x 0.5 cm (stitch marks highest count). One candidate lymph node is. identified at the stitched area; this is inked blue. Additionally, two more lymph node candidates are. identified. Three lymph node candidates are submitted for frozen section diagnosis 1, and. subsequently submitted in cassette A1. The remaining fibrofatty tissue is submitted in cassette A2. Part B, additionally labeled ". consists of a single firm, unoriented, oval piece of. yellow-pink fibrofatty tissue measuring 2.5 x 1.7 x 0.7 cm. One side of the specimen is inked blue. and the opposite side is Inked green. The specimen is bread-loafed, and two central representative. sections are submitted for frozen section diagnosis 2, with the frozen section remnant submitted in. cassette B1. The remaining tissue is submitted in cassettes B2-B3. Part C is additionally labeled ". - SPECIMEN TYPE: Partial mastectomy. - SKIN ELLIPSE: Not present. - NIPPLE: Not present. - ORIENTATION: - Long suture: Lateral. - Short suture: Superior. - INKING (for microscopic evaluation): - Black: Deep. - Green : Anterior inferior. - Blue: Anterior superior. - SIZE OF SPECIMEN: Working Draft. - Medial-Lateral dimension: 4.3 cm. - Superior-Inferior dimension: 4 cm. - Anterior-Posterior dimension: 1.8 cm. - TOTAL NUMBER OF SLICES: Eight. - First slice (slice #1): Medial margin. - Last slice (slice #8): Latera margin. - GROSS PATHOLOGY: The specimen consists of a 22 gm partial mastectomy specimen. A tan-pink,. irregular, firm mass is noted in the more superior aspect of the specimen, which measures 1.5 x 0.7 x. 0.7 cm. A portion is taken for tissue banking. The mass appears to be present in slices 3-6. The. mass appears to come within <0.1 cm away from the deep and anterior-superior margins in slice 4. The mass comes within 0.2 cm away from the anterior- inferior margin in slice 3. No localization. needle or specimen mammogram are included in the specimen. Representative sections are submitted. as follows: Cassette C1: Perpendicular representative sections of medial margin, slice 1. Cassette C2: Middle slice 2. Cassettes C3-C4: Closest approach to anterior inferior margin, entire slice 3. Cassettes C5-C6: Closest approach to deep and anterior superior margins, entire slice. 4. Cassette C7: Superior slice 5. Cassette C8: Middle slice 6. Cassette C9: Inferior slice 8. Cassette C10: Perpendicular sections of slice 8, lateral margin. Pathology Resident. /Patholoalst. Fee Codes: Addenda. Addendum. Date Complete: Addendum Comment. An immunohistochemical test for estrogen and progesterone receptors was performed by manual. morphometry on block C7. The test for estrogen receptors is negative. There is no nuclear staining in any of tumor cells. Internal positive control is present. The test for progesterone receptors is negative. There is no nuclear staining in any of tumor cells. Internal positive control is present. Result of HER2/neu test: This carcinoma is negative for HER2/neu oncoprotein over-expression. An immunohistochemical assay was performed by manual morphometry on block C7 using the CB11. monoclonal antibody to HER2/neu oncoprotein. The staining intensity of this carcinoma was 0 on a. scale of 0-3. Carcinomas with staining intensity scores of 0 or 1 are considered negative for over-expression of. HER2/neu oncoprotein. Those with a staining intensity score of 2 are considered indeterminate. We and others have observed that many carcinomas wit. Working Draft. staining Intensity scores of 2 do not show gene amplification. All carcinomas with staining intensity scores of 2 are therefore. submitted for FISH testing. The results of the HISH test are Issued directly frum the molecular cytogenetics laboratory. Carcinomas with staining intensity scores of 3 are considered positive for over-expression of HER2/neu oncoprotein. Tumors in. this category show an excellent correlation between the results of immunohistochemical and FISH testing, and almost always show. gene amplification. The immunonernvidaep stain(s) reported above were developed and their performance characteristics determined by the. They have not been cleared or approved by the U. S. Food and Drug Administration. ine FDA has determined that such Crearance or approval is not necessary. These tests are used for clinical purposes. They should. not be regarded as investigational or for research. This laboratory is certified under the Clinical Laboratory Improvement. Amendments of 1988 ("CLIA") as qualified to perform high-complexity clinical testing. sthologist. Other Specimens. Specimen Class: Accessioned: Specimen(s) Received: Right Breast, Fine Needle Aspiration. Final Diagnosis. Right Breast, Fine Needle Aspiration: Cyst contents; see comment. Specimen Class: Accessioned. Specimen(s) Received: A: Right breast scar, B: Right breast, partial mastectomy w/o lymph nodes. Final Diagnosis. A. Skin, right breast, excision: 1. Skin with scar and surgical site changes. 2. No carcinoma. B. Right breast, partial mastectomy: 1. Benign breast tissue. 2. Surgical site changes. 3. No carcinoma. Specimen Class: Accessioned: Specimen(s) Received: Right Breast, Fine Needle Aspiration. Final Diagnosis. Right Breast, Fine Needle Aspiration: Adenocarcinoma, see. comment. Specimen Class: Accessioned. Specimen(s) Received: Cervical/Endocervical, Thin Prep Imaged. Working Draft. Final Diagnosis. Cervical/Endocervical, Thin Prep Imaged. NEGATIVE FOR INTRAEPITHELIAL LESION OR MALIGNANCY. SPECIMEN ADEQUACY: Satisfactory for evaluation. Transformation zone components are present. FND OF REPORT.

expanded version (tokens=2543) : 
 Histological classification: 
- Left axilla sentinel lymph nodes, dissection: No tumor (0/3)
- Right medial breast, excision: No tumor; Usual ductal hyperplasia, sclerosing adenosis and calcifications
- Right breast, partial mastectomy: Invasive ductal carcinoma, 2.2 cm, grade 3; Ductal carcinoma in situ, high nuclear grade with necrosis

Subtype: Basal

Description of necrosis: Present in ductal carcinoma in situ (DCIS)

Tumor infiltrating lymphocytes: Not mentioned

Histological grade: 
- Invasive tumor grade: 3
- DCIS nuclear grade: High grade

Nuclear grade: 3 points for invasive tumor

Lymphovascular invasion: None

Calcification: Present in DCIS and benign ducts

Receptor status:
- Estrogen receptor: Negative
- Progesterone receptor: Negative
- HER2/neu: Negative

Ancillary testing results: Immunostains for ER/PR and Her2 neu were performed and reported in an addendum. All margins were oriented, inked, and examined microscopically. A test for HER2/neu oncoprotein over-expression was performed using the CB11 monoclonal antibody to HER2/neu oncoprotein. The staining intensity of this carcinoma was 0 on a scale of 0-3. Carcinomas with a staining intensity score

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2699) : 
 The patient has invasive basal subtype ductal carcinoma in situ (DCIS) with high nuclear grade and necrosis. No tumor was found in the left axilla sentinel lymph nodes, while the right breast shows no tumor, usual ductal hyperplasia, sclerosing adenosis, and calcifications. Results of receptor status show negative for estrogen receptor, progesterone receptor, and HER2/neu. Margins are negative within boundaries. The patient has stage pT2NOMX cancer as per AJCC/UICC staging.

