prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Basal, Specimen #: Race: WHITE. Physician (s) : AMENDED. SPECIMEN: A: SENTINAL B: RIGHT BREAST TISSUE C: NON SENTINAL LYMPH. D: SENTINAL LYMPH NODE. FINAL DIAGNOSIS: A. LYMPH NODE, SENTINEL NUMBER ONE, BIOPSY: - ONE LYMPH NODE NEGATIVE FOR TUMOR BY H&E AND IMMUNOHISTOCHEMISTRY. B. BREAST, RIGHT, SIMPLE MASTECTOMY: - INFILTRATING DUCTAL CARCINOMA, POORLY-DIFFERENTIATED BY COMBINED. HISTIOLOGIC CRITERIA. - TUMOR SIZE 1.8 CM. - ASSOCIATED DUCTAL CARCINOMA IN SITU, NUCLEAR GRADE III WITH NECROSIS. AND PROMINENT LYMPHOID INFILTRATE COMPRISING 10-15% OF TUMOR. ESTROGEN RECEPTOR: NEGATIVE IN INFILTRATING AND IN SITU CARCINOMA. PROGESTERONE RECEPTOR: NEGATIVE IN INFILTRATING AND IN SITU. CARCINOMA. - HER2 NEU BY IMMUNOHISTOCHEMISTRY: 2+ (WEAKLY POSITIVE). - HER2 NEU BY FISH: NOT AMPLIFIED (1.4). - MARGINS NEGATIVE FOR TUMOR. - NO RESIDUAL PAGET'S DISEASE OR LACTIFEROUS DUCT INVOLVEMENT. - MICROCALCIFICATIONS IN NEOPLASTIC BREAST TISSUE. - UNINVOLVED BREAST TISSUE SHOWS FIBROCYSTIC CHANGES AND SCLEROSING. ADENOSIS. C. LYMPH NODE, NON SENTINEL, BIOPSY. - ONE BENIGN LYMPH NODE. D. LYMPH NODE, SENTINEL NUMBER TWO, BIOPSY: - ONE LYMPH NODE NEGATIVE FOR TUMOR BY H&E AND IMMUNOHISTOCHEMISTRY. COMMENT: The above results were reported in. L on. Estrogen and progesterone receptors were evaluated by immunohistochemical. Specimen # : FINAL DIAGNOSIS (continued) : methods. A positive test is defined as easily discernable nuclear. staining in more than 5% of the tumor cells. The specimen was evaluated for HER-2/Neu (c-erbB2) overexpression by. immunohistochemical methods (DAKO Hercep Test) . Staining is interpreted. on a scale of 0 to 3+ with positivity defined as 2+ or greater. Specimens. with a weakly positive (2+) Hercep Test are further evaluated by. fluorescence in situ hybridization (PathVysion FISH assay) to detect. presence or absence of Her-2/neu gene amplification. CLINICAL DIAGNOSIS AND HISTORY: (None Given}. GROSS DESCRIPTION: A. SENTINEL Received in formalin, labeled with the patient's name,. and designated "SENTINEL LYMPH NODE NUMBER ONE" is a specimen consisting. of a 2.0 x 1.4 x 1.0 cm lymph node. A small portion was submitted for the. CBCP protocol. 1C1NS. B. RIGHT BREAST TISSUE Received fresh, labeled with the patient's name,. and designated "RIGHT BREAST TISSUE" is a specimen consisting of a 245.0. gram simple mastectomy, 18.0 cm x 13.5 cm x 3.0 cm in dimension. There is. a 15.0 cm x 4.0 cm ellipse of nipple-bearing skin. The deep margin is. inked in black. On sectioning, a 1.8 cm tumor is identified in the. mid-center portion of the breast. The tumor abuts, but does not grossly. involve the deep margin. The remaining tissue is extensively fibrosis with. admixed fat. Sections of tumor, grossly normal fibrous breast tissue, and. skin harvested for the CBCP protocol; mirror images for Histology are as. follows: Slide Key: B1: Tumor (CBCP) ; B2: Fibrous tissue, 1.0 cm medial to tumor. (CBCP) i B3: Fibrous tissue, 2.0 cm medial to tumor (CBCP) ; B4: Fibrous. tissue, 5.0 cm medial to tumor (CBCP) ; B5: Skin, near medial tip (CBCP) ;. Specimen #: GROSS DESCRIPTION (continued) : B6: Nipple; B7: Tumor and deep margin; B8-B10 Representative tumor; B11: Medial upper quadrant; B12: Medial lower quadrant; B13 : Lateral lower. quadrant; B14: Lateral upper quadrant. 14CFSS. C. NON SENTINEL LYMPH Received fresh, labeled with the patient's name,. and designated "NON-SENTINEL LYMPH NODE" is a specimen consisting of a. 1.5. cm x 0.8 cm x 0.5 cm tan lymph node with a scant amount of attached. yellow, lobular adipose tissue. 1CF. D. SENTINEL LYMPH NODE Received fresh, labeled with the patient's. name, and designated "SENTINEL LYMPH NODE NUMBER TWO" is a specimen. consisting of a 1.4 cm x 0.8 cm x 0.4 cm yellow, white soft tissue. fragment with two staples and an unoriented suture. CA. i.

expanded version (tokens=1627) : 
 Histological classification: The breast pathology report indicates infiltrating ductal carcinoma, which is a common type of breast cancer, poorly differentiated by combined histological criteria. There was also a presence of associated ductal carcinoma in situ with nuclear grade III and necrosis. 

Subtype: The subtype of the breast cancer is basal.

Necrosis: Necrosis was reported in the associated ductal carcinoma in situ.

Tumor infiltrating lymphocytes: The report mentions a prominent lymphoid infiltrate comprising 10-15% of the tumor.

Histological grade: The report mentions that the infiltrating ductal carcinoma is poorly differentiated. However, there is no specific mention of the histological grade of the DCIS.

Nuclear grade: The associated ductal carcinoma in situ was found to be nuclear grade III with necrosis.

Lymphovascular invasion: There is no mention of lymphovascular invasion in the report.

Calcification: Microcalcifications were observed in the neoplastic breast tissue.

Receptor status: The report indicates negative hormone receptor status for both estrogen and progesterone receptors. HER2/neu was found to be weakly positive by immunohistochemistry (2+) but not amplified by FISH.

IHC and ancillary testing: Estrogen and progesterone receptors were evaluated by immunohistochemical methods. HER2/Neu (c-erbB2) was evaluated using immunohistochemical methods (DAKO Hercep Test) and further evaluated with

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1785) : 
 The breast pathology report indicates infiltrating ductal carcinoma, poorly differentiated by combined histological criteria with associated nuclear grade III ductal carcinoma in situ and necrosis. The subtype of the breast cancer is basal. A prominent lymphoid infiltrate was observed in 10-15% of the tumor. Microcalcifications were identified in neoplastic breast tissue. Hormone receptor status was negative for both estrogen and progesterone receptors, but HER2/neu was weakly positive (2+) by immunohistochemistry and not amplified by FISH.

