prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Her2, LOGY REPORT. Specimen # : (Age. F. Race: WHITE. AMENDED ICD-0-3. SPECIMEN: A: RIGHT BREAST AND AXILLARY CONTENTS. B: ADDITIONAL RIGHT BREAST TISSUE. FINAL DIAGNOSIS: A & B. BREAST, RIGHT, MODIFIED RADICAL MASTECTOMY WITH AXILLARY LYMPH. NODES, EXCISION: TUMOR TYPE: APOCRINE CARCINOMA, INFILTRATING (A2,A3,A14, A15). (HISTIOCYTOID SUBTYPE) (SEE COMMENT). NOTTINGHAM GRADE: MODERATELY DIFFERENTIATED (G2). NOTTINGHAM SCORE: 7/9. (Tubules= 3, Nuclei= 3, Mitoses= 1i mitotic count 3 per 10 HPF at. 40x power). TUMOR SIZE (GREATEST DIMENSION) : 4.5 CM (MEASURED GROSSLY; See. comment). TUMOR NECROSIS: ABSENT IN INFILTRATING COMPONENT, PRESENT (COMEDO,. N-SITU TYPE) IN DCIS. MICROCALCIFICATIONS PRESENT IN STROMA. VENOUS / LYMPHATIC INVASION: PRESENT (A10,A14). MARGINS : NEGATIVE. -DISTANCE OF TUMOR FROM NEAREST MARGIN IS 1.1 CM, FROM DEEP MARGIN. (A3). INTRADUCTAL COMPONENT: EXTENSIVE. LYMPH NODES: ONE OF 18 POSITIVE FOR TUMOR BY IHC ONLY (SEE COMMENT). NIPPLE INVOLVEMENT: ABSENT. SKIN INVOLVEMENT : ABSENT. MULTICENTRICITY ABSENT. ESTROGEN RECEPTORS: NEGATIVE (PREVIOUSLY EVALUATED FROM. PROGESTERONE RECEPTORS: NEGATIVE (PREVIOUSLY EVALUATED FROM. HER 2 NEU by IHC: POSITIVE (3+) (PREVIOUSLY EVALUATED FROM. $05-12958). PATHOLOGIC STAGE: pT2 NO (i+) MX (AJCC Stage II). ADDITIONAL PATHOLOGIC CHANGES CYSTIC CHANGE, SCLEROSING ADENOSIS,. FIBROADENOMATOID CHANGE, APOCRINE METAPLASIA. COMMENT: COMMENT #2 (. Specimen #: FINAL DIAGNOSIS (continued) : This case is amended to change the lymph node assessment to the above from. a prior assessment of. "LYMPH NODES: 18 NEGATIVE FOR TUMOR. ", and to change the stage to. T2 NO (i+) from T2 NO. Dr. requested additional evaluation of the. lymph nodes on this patient to collaborate with the PET findings of a. positive node, so the nodes in A10, A11, A12, A19 and A20 were evaluated. with keratin. In A10, the node originally showing pericapsular lymphatic. involvement, the keratin shows individual cells and one subcapsular. cluster of tumor cells less than 0.2 mm in diameter. Dr. was informed of this change in report today by email. ORIGINAL COMMENT: The tumor was too large for microscopic measurement, so exact. measurement is not possible. Some of the DCIS component may have been. included in the gross measurement, but the bulk of tumor is infiltrative. and represents at least a T2 lesion. Slide A10 contains a lymph node with lymphvascular space invasion just. outside of the capsule. We are interpreting this as a negative node. This report was amended. due to a typographical error in the. patient history listing her age incorrected as years. Additionally, the. pathologic stage was changed from N1 to NO, another typographical error. CLINICAL DIAGNOSIS AND HISTORY: year old female with invasive ductal carcinoma of right breast and. positive for axillary lymph nodes. Presents for modified radical. mastectomy. PRE-OPERATIVE DIAGNOSIS: Right breast cancer. POST-OPERATIVE DIAGNOSIS: Right breast cancer. GROSS DESCRIPTION. A. Received fresh consists of a 504 gram right mastectomy specimen single. stitch medial and double stitch superior. Specimen measures 24 cm superior. to inferior, 21 cm medial to lateral, and 3 cm anterior to posterior. The. jightly pigmented skin ellipse measures 12 x 5 cm, centrally located. 3. Specimen #: GROSS DESCRIPTION (continued) : everted nipple measuring 1.5 x 1.5 x 1.2 cm with no discharge. No scars. inked black. Specimen serially sectioned to reveal fairly well. identified. Superficial upper outer quadrant is inked blue and deep margin. circumscribed pink firm mass measuring 4.5 x 2.5 x 2.0 cm. The mass. focal hemorrhage and lies within a bed of dense, diffusely nodular,. shows. and 0.5 cm from blue superficial margin. Remaining tissue shows scattered margin. focally necrotic fibrous tissue. The mass is located 1 cm from deep. cysts measuring up to 0.4 cm. Multiple indurated foci are also seen. node is seen within the upper outer quadrant. within the upper inner quadrant and lower inner quadrant. A 0.7 cm lymph. A separately received portion of axillary tail measures 10 x 3 x 1. 0 cm. and oriented with stitch on high end. Five lymph nodes are identified. measuring 0.7 to 1.0 cm. The specimen is submitted as follows: A1: skin. A2 mass, central. A3 : margin. A4: lateral mass. A5: upper outer quadrant. A6: lower outer quadrant. A7: lower inner quadrant. A8: upper inner quadrant. A9: intramammary lymph node. A10: two high axillary lymph nodes bisected. All: two mid axillary lymph nodes bisected. A12: one low axillary lymph node. A13: nipple. A14-A17: upper outer quadrant mass lateral to medial. A18: high axillary lymph node. A19: middle axillary lymph node. A20: low axillary lymph node. 20CF. B. Received in formalin labeled with patient's name. designated "RIGHT BREAST TISSUE WITH AXILLARY CONTENTS" consists of a 1.0. x 1.0 x 0.4 cm piece of red and yellow soft tissue. Specimen submitted. entirely in one cassette.

expanded version (tokens=1823) : 
 Histological classification: The tumor type is identified as apocrine carcinoma, infiltrating with a histiocytoid subtype. There is also ductal carcinoma in situ (DCIS) present, with comedo type necrosis.

Subtype: The tumor subtype is identified as HER2 positive.

Necrosis: Necrosis is absent in the infiltrating component but present in the DCIS component.

Tumor infiltrating lymphocytes: There is no mention of tumor infiltrating lymphocytes in the report.

Histological grade: The tumor is moderately differentiated (G2), with a Nottingham score of 7/9.

Nuclear grade: Not mentioned in the report.

Lymphovascular invasion: Venous/lymphatic invasion is present.

Calcification: Microcalcifications are present in the stroma.

Receptor status: The tumor is estrogen receptor (ER) negative and progesterone receptor (PR) negative.

IHC and ancillary testing results: HER2 is positive (3+).

Additional findings: There is evidence of cystic change, sclerosing adenosis, fibroadenomatoid change, and apocrine metaplasia. The tumor size is 4.5 cm, and there is one positive lymph node out of 18 evaluated. The margins are negative, and there is no nipple or skin involvement. The pathologic stage is pT2 NO (i+) MX (AJCC Stage II).

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2021) : 
 This is a report of a 505-gram right breast and axillary contents specimen from a  year-old female with invasive ductal carcinoma. The diagnosis is Apocrine carcinoma, infiltrating (HER2+), with ductal carcinoma in situ present. The tumor size is 4.5 cm, moderately differentiated (G2), and has venous/lymphatic invasion. The margins are negative, ER/PR is negative, and HER2 is positive (3+). One out of the eighteen lymph nodes is positive for tumor by IHC only. The pathologic stage is pT2 NO (i+) MX (AJCC Stage II). No nipple or skin involvement was observed; further ancillary analysis revealed cystic change, scl

