prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - specimen #: : lace: WHITE. Physician (s) : AMENDED. SPECIMEN: A: RIGHT BREAST B: RIGHT BREAST TISSUE FROM INFERIOR FLAP. C: RIGHT SENTINEL LYMPH NODE #1. D: RIGHT SENTINEL LYMPH NODE #2. FINAL DIAGNOSIS: A. RIGHT BREAST, MASTECTOMY: -TUMOR TYPE: INVASIVE DUCTAL CARCINOMA WITH LOBULAR FEATURES. -NOTTINGHAM GRADE MODERATELY DIFFERENTIATED (G2). -NOTTINGHAM SCORE: 6/9 (TUBULES = 3, NUCLEI = 2, MYTOSES= 1) . -TUMOR SIZE: GREATEST DIMENSION: TUMOR 1 (UPPER INNER QUADRANT) : at least 1.1 CM. (measured on microscopic slide, extensively involves margin). TUMOR 2 (CENTRAL MASS) : 2.5 CM (MEASURED GROSSLY) . - TUMOR NECROSIS: ABSENT. -MICROCALCIFICATIONS: - ABSENT. - -VENOUS INVASION ABSENT. -MARGINS: INVASIVE TUMOR EXTENSIVELY INVOLES THE SUPERFICIAL (ANTERIOR,. BLUE INK) MARGIN, UPPER INNER QUADRANT (SLIDES A2-A4) . INTRADUCTAL COMPONENT NEAREST INKED SURGICAL MARGIN: 5 MM. (SUPERIOR, ANTERIOR, SLIDE A2). -INTRADUCTAL COMPONENT MINIMAL. -LYMPH NODES REPORTED SEPARATELY BELOW IN C AND D. -NIPPLE INVOLVEMENT: ABSENT. - SKIN INVOLVEMENT: ABSENT. -MULTICENTRICITY: - PRESENT. - -ADDITIONAL STUDIES: (See comment.). -TUMOR 1, UPPER INNER QUADRANT. ESTROGEN RECEPTOR: POSITIVE (95% NUCLEAR STAINING). PROGESTERONE RECEPTOR: POSITIVE (5% NUCLEAR STAINING). HER-2 BY IMMUNOHISTOCHEMISTRY: NEGATIVE (1+). - TUMOR 2, CENTRAL: ESTROGEN RECEPTOR: POSITIVE (95% NUCLEAR STAINING). PROGESTERONE RECEPTOR POSITIVE (15% NUCLEAR STAINING). HER-2 BY FISH NOT AMPLIFIED RATIO 1. 1. Specimen # : FINAL DIAGNOSIS (continued) : (ESTROGEN RECEPTOR, PROGESTERONE RECEPTOR, AND HER-2 STUDIES WERE. PERFORMED ON AN EARLIER BIOPSY AT SCOTTSDALE PATHOLOGY CONSULTANTS,. - PATHOLOGIC STAGE: pT2NO (i-)MX -. -ADDITIONAL PATHOLOGIC CHANGES : CYSTIC CHANGE, APOCRINE METAPLASIA,. COLUMNAR CELL CHANGE. B. RIGHT BREAST TISSUE FROM INFERIOR FLAP, EXCISION: -NO SIGNIFICANT PATHOLOGIC CHANGE. C. SENTINEL LYMPH NODE #1, BIOPSY: -NO METASTATIC DEPOSIT IDENTIFIED IN ONE EXAMINED LYMPH NODE. (MULTIPLE SLIDES STAINED WITH HEMATOXYLIN&EOSIN AND WITH IMMUNOSTAIN. FOR CYTOKERATIN). D. SENTINEL LYMPH NODE RIGHT AXILLA #2, BIOPSY: -NO METASTATIC DEPOSIT IDENTIFIED IN ONE EXAMINED LYMPH NODE. (MULTIPLE SLIDES STAINED WITH HEMATOXYLIN&EOSIN AND WITH IMMUNOSTAIN. FOR CYTOKERATIN). COMMENT: The smaller tumor in the upper inner quadrant is present at the margin and. involves an inked surgical margin over a cut arc of 4 to 5 mm. Because. the greatest extent of the tumor cannot be assessed, this tumor might. otherwise be classified pTX. The cenral mass appears to be larger and is. completely excised. Its greatest dimension of 2.5 cm is the basis of the. pathologic T stage of pT2. AMENDMENT COMMENT. The report is amended to add evaluation of markers (ER, PR, Her2). performed on the upper inner quadrant tumor, sections of block A2. The. studies reported for the central tumor are from the report of a biopsy. designated "12:00" at another institution. NTER. specimen #: CLINICAL DIAGNOSIS AND HISTORY: breast cancer year old female. GROSS DESCRIPTION: A. Received fresh labeled with the patient's name. designated "RIGHT MASTECTOMY SPECIMEN" is a 278 gram right mastectomy. oriented with short stitch superior, long lateral and double deep. The. specimen measures 16 cm medial to lateral, 14 cm superior to inferior and. 3. cm anterior to posterior. The lightly pigmented superficial skin ellipse. measures 10 x 3 cm and displays a 1.7 cm everted nipple free of discharge. No scars are noted. The deep margin is inked black and the superficial. surface of the upper inner quadrant is inked blue. Serially sectioned to. reveal a 0.6 x 0.4 x 0.3 cm firm pink white mass abutting the superficial. margin of the UIQ (1:00) . The cut surface shows focal congestion. consistent with a previous biopsy. The mass comes to within 2.0 cm of the. deep margin. Located approximately 1.0 cm lateral to this mass is a very. poorly defined mass of similar appearance which measures 2.5 x 2.5 x 1.0. cm and involves the upper mid and central portions of the breast. The. central mass comes to within 1.0 cm of the deep margin. The remainder of. the specimen is composed of moderately dense markedly nodular fibrous. tissue. The adipose tissue compromises 20% of the specimen is. unremarkable. No lymph nodes are identified. Summary of sections: A1: one piece, skin. A2-A4: one piece in each, upper inner quadrant mass anterior margin. A5: one piece, central mass deep margin. A6: one piece, central mass. A7: upper outer quadrant. A8: lower outer quadrant. A9: lower inner quadrant. A10: upper inner quadrant. All: one piece, nipple. A12-A13 one piece each, representative mass. 13CF. Matched sections of A1-A2 and A6-A10 are submitted in. for CBCP. protocol. B. Received in formalin labeled with the patient's name. designated "BREAST TISSUE FROM INFERIOR FLAP" are multiple pieces of. yellow tan lobulated adipose tissue measuring 4.7 x 3.5 x 2.0 cm in. aggregate dimension. Sectioning reveals grossly unremarkable fibroadipose. tissue throughout. Representative sections submitted. Summary of sections : B1-B4: one piece in each, 4C4. C. Received fresh labeled with the patient's name. Specimen # : GROSS DESCRIPTION (continued) : designated "SENTINEL LYMPH NODE #1" is a single 2 x 1 x 0.3 cm pink yellow. lymph node. On sectioning cut surface shows a fatty hilum. The specimen is. bisected and entirely submitted in C1 and C2. Summary of sections: C1-C2: one piece in each, suspected lymph node. D. Received in formalin labeled with the patient's name. designated "SENTINEL NODE RIGHT AXILLA #2" is a single 1.1 x 1.0 x 0.5 cm. pink yellow lymph node. On sectioning the cut surface shows a fatty hilum. The specimen is bisected and entirely submitted in one cassette. Summary. of sections : D1: two pieces.

expanded version (tokens=2131) : 
 Histological classification: 

The patient has been diagnosed with invasive ductal carcinoma with lobular features in the right breast. The tumor was found to be moderately differentiated, with a Nottingham score of 6/9 (tubules = 3, nuclei = 2, mytoses = 1). The tumor size was at least 1.1 cm (on microscopic slide) in the upper inner quadrant, and 2.5 cm (measured grossly) in the central mass. 

Subtype: 

The tumor was diagnosed as invasive ductal carcinoma with lobular features. 

Necrosis: 

The tumor necrosis was found to be absent. 

Tumor infiltrating lymphocytes: 

There is no mention of tumor infiltrating lymphocytes. 

Histological grade: 

The histological grade of the tumor was found to be moderately differentiated (G2). 

Nuclear grade: 

The nuclear grade of the tumor was found to be 2. 

Lymphovascular invasion: 

There was no evidence of vascular invasion. 

Calcification: 

Microcalcifications were absent. 

Receptor status: 

The receptor status of the tumor was positive for estrogen receptor (95% nuclear staining) and positive for progesterone receptor (5% nuclear staining) in tumor 1 (upper inner quadrant) and positive for estrogen receptor (95% nuclear staining) and positive for progesterone receptor (15% nuclear staining) in tumor 2 (central

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2299) : 
 Diagnosis: Invasive ductal carcinoma with lobular features in right breast, moderately differentiated (G2). Tumor size: at least 1.1 cm in upper inner quadrant and 2.5 cm in central mass. Necrosis absent, microcalcifications absent, lymphovascular invasion absent. Estrogen receptor positive (95% nuclear staining), progesterone receptor positive (5% nuclear staining) in tumor 1; Estrogen receptor positive (95% nuclear staining), progesterone receptor positive (15% nuclear staining)  in tumor 2. HER-2 negative.


