prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, I. Specimen #: (Age: F Race: WHITE. Physician (s) : SPECIMEN: LEFT BREAST. FINAL DIAGNOSIS: BREAST, LEFT, MASTECTOMY: - MODERATELY DIFFERENTIATED (GRADE II/III) INFILTRATING LOBULAR CARCINOMA. NOTTINGHAM SCORE: 6 OF 9 (Tubule formation = 3 Nuclear pleomorphism =. 2, and Mitotic activity = 1). TUMOR SIZE (GREATEST DIMENSION) : 3.5 CM (MEASURED GROSSLY) (SEE. COMMENT). TUMOR NECROSIS: NOT PRESENT. MICROCALCIFICATIONS: FOCALLY PRESENT, ASSOCIATED WITH INVASIVE. CARCINOMA, AS WELL AS, BENIGN DUCTS. VENOUS / LYMPHATIC INVASION: NOT IDENTIFIED. MARGINS NEGATIVE. - DISTANCE OF TUMOR FROM NEAREST INKED BLACK (DEEP) TISSUE EDGE IS 0.5. CM (SLIDE A7) . INTRADUCTAL COMPONENT: LOBULAR CARCINOMA IN SITU. NIPPLE INVOLVEMENT: NOT PRESENT. SKIN INVOLVEMENT: NOT PRESENT. LYMPH NODES: ONE (1) SENTINEL LYMPH NODE NEGATIVE PER PRIOR. SURGICAL SPECIMEN. ESTROGEN RECEPTORS: POSTTIVE (95% NUCLEAR STAINING PER PRIOR. SURGICAL SPECIMEN. PROGESTERONE RECEPTORS: NEGATIVE (NO DETECTABLE NUCLEAR. STAINING PER PRIOR SURGICAL SPECIMEN. HER2/NEU: WEAKLY POSITIVE BY IMMUNOHISTOCHEMISTRY (2+). NEGATIVE BY. FISH (HER2/CEP17 RATIO: 0.9) PER PRIOR SURGICAL SPECIMEN. PATHOLOGIC STAGE: pT2 NO MX. - ADDITIONAL PATHOLOGIC CHANGES. FLORID USUAL DUCTAL HYPERPLASIA. FIBROADENOMATOID CHANGE. FIBROCYSTIC CHANGES TO INCLUDE STROMAL FIBROSIS, CYST FORMATION, AND. APOCRINE METAPLASIA. PRIOR BIOPSY SITE CHANGES. Comment: The lobular differentiation is supported by negative E-cadherin. cytoplasmic staining and strongly positive 34betaEl2 ( ) perinuclear. cytoplasmic staining. There are microscopic foci of infiltrating lobular. carcinoma and LCIS in a random representative section of the lower outer. quadrant (slide A10) The morphology is identical to the main tumor. Specimen #: FINAL DIAGNOSIS (continued) : mass. These foci likely represent extension of the main tumor rather than. true multifocal carcinoma. CLINICAL DIAGNOSIS AND HISTORY: {None Given}. GROSS DESCRIPTION: A. Received fresh labeled with the patient's name. and. designated "LEFT BREAST" is a 413 gram simple mastectomy specimen oriented. with sutures (long lateral, short superior) measuring 22 cm medial to. lateral, 16 cm superior to inferior, and 4. 8 cm anterior to posterior. An. ellipse of unremarkable nipple bearing skin measuring 5.5 x 3 cm is. present. The specimen is inked as follows: blue superior superficial,. green inferior superficial, black deep. Sectioning reveals a 3.5 x 3.5 x 3. cm firm poorly defined mass at the 2-3:00 position, 0.2 cm from the inked. deep margin. The cut surface of the tumor is yellow tan and gritty. The. remaining tissue is mostly fatty with admixed patches of white fibrous. tissue located centrally. Two sections of tumor, a single section of. skin, and a single section of grossly normal breast are collected for CBCP. protocol with matched paraffin sections in A2, A3, A1, and A4. respectively. The specimen was in formalin for 76 hours and 5 minutes. Summary of cassettes: A1: skin. A2: tumor lateral. A3: tumor medial. A4: grossly normal breast central. A5-A7: random additional sections of tumor. A8: left upper outer quadrant. A9: left upper inner quadrant. A10: left lower outer quadrant. A11: left lower inner quadrant. A12: nipple.

expanded version (tokens=1393) : 
 Histological classification: Moderately differentiated infiltrating lobular carcinoma with a Nottingham score of 6 out of 9 (tubule formation = 3, nuclear pleomorphism = 2, and mitotic activity = 1), without necrosis. Intraductal component includes lobular carcinoma in situ.

Grade: Grade II/III (moderately differentiated)

Size: 3.5 cm (measured grossly)

Necrosis: Not present

Lymphovascular invasion: Not identified

Calcification: Focally present, associated with invasive carcinoma, as well as benign ducts.

Receptor status: Estrogen receptors are positive (95% nuclear staining), progesterone receptors are negative (no detectable nuclear staining). HER2/neu is weakly positive by immunohistochemistry (2+), but negative by FISH (HER2/CEP17 ratio: 0.9).

Ancillary testing results: Negative E-cadherin cytoplasmic staining and strongly positive 34betaEl2 perinuclear cytoplasmic staining support lobular differentiation. There are microscopic foci of infiltrating lobular carcinoma and LCIS in a random representative section of the lower outer quadrant, which likely represent extension of the main tumor rather than true multifocal carcinoma. 

Other pathological changes: Florid usual ductal hyperplasia, fibroadenomatoid change, fibrocystic changes including stromal fibrosis, cyst

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1563) : 
 Final diagnosis is a moderately differentiated infiltrating lobular carcinoma without necrosis. No lymphovascular invasion or nipple/skin involvement identified. Tumor size is 3.5 cm and HER2/neu is weakly positive by immunohistochemistry but negative by FISH. Estrogen receptors are positive and progesterone receptors are negative. Calcifications are focally present with benign ducts and invasive carcinoma. Intraductal component includes lobular carcinoma in situ with microscopic foci of infiltrating lobular carcinoma in the lower outer quadrant likely representing extension of the main tumor rather than multifocal carcinoma.

