prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Specimen #: (Age: Race: Physician (s) : AMENDED. SPECIMEN: A: LEFT BREAST LUMPECTOMY. B: NEW MEDIAL MARGIN, LEFT BREAST. C: SENTINEL LYMPH NODE #1 D: AXILLARY CONTENTS Site: breast, NOS. FINAL DIAGNOSIS: A. BREAST, LEFT, LUMPECTOMY : - INFILTRATING (INVASIVE) AND INTRADUCTAL CARCINOMA, COMEDO-TYPE,. BLOOM-RICHARDSON GRADE. 9 (3 + 3 + 3). TUMOR INVOLVEMENT AT INFERIOR, SUPERIOR, AND ANTERIOR MARGINS. SPECIAL STAINS PENDING, ADDENDUM TO FOLLOW. B. BREAST, LEFT NEW MEDIAL MARGIN, BIOPSY: HIGH GRADE INTRADUCTAL CARCINOMA, COMEDO-TYPE, BLOOM RICHARDSON GRADE. 9 (3 + 3 + 3). - TUMOR INVOLVMENT PRESENT AT MARGIN. C. LYMPH NODE, SENTINEL LYMPH NODE #1, BIOPSY: - POSITIVE FOR METASTATIC CARCINOMA. - CYTOKERATIN STAIN POSITIVE FOR METASTATIC CARCINOMA. D. SOFT TISSUE, AXILLARY CONTENTS, BIOPSY: - NO EVIDENCE OF MALIGNANCY. AJCC PATHOLOGIC STAGING: pT2 pN1c pMX. COMMENT: AMENDMENT. Case amended by Dr. in the absence of the primary pathologist, Dr. to report results of HER2 analysis by mmunohistochemistry. Hercep Test) : HER2: WEAKLY POSITIVE (2+). NOTE: HER2 by FISH analysis previously performed on. 1. FISH: Not. amplified (1.3) . FOR OFFICIAL, USE ONLY - PERSONAL DATA -. FOR. Specimen #: FINAL DIAGNOSIS (continued) : CLINICAL DIAGNOSIS AND HISTORY: -year-old. with diagnosis of left breast cancer. GROSS DESCRIPTION: A. LEFT BREAST LUMPECTOMY received fresh labeled with the patient's name. and designated "LEFT BREAST LUMPECTOMY" is a piece of fatty tissue, 8. 0 x. 5.0 x 6.5 x 1.8 cm, impaled with a needle localization wire. The specimen. is oriented with sutures (short=superior, long=lateral) and is inked as. follows: Red=medial and lateral, blue=superior, green=inferior,. yellow=anterior, black=posterior. The needle localization wire enters the. specimen at the lateral margin. The tip of the wire is embedded in the mid. portion of the specimen. The accompanying specimen radiograph is reviewed. and shows numerous calcifications in the area of the wire localization. The specimen is serially sectioned, medial to lateral, revealing a poorly. differentiated mass, 3.0 cm in greatest dimension, corresponding to the. area of radiographic abnormality. The mass is firm and nodular, and. contains at least two vell-circumscribed masses with a tan, gritty cut. surface. The largest of these well-circumscribed - masses measures 1.2 cm in. greatest dimension. The 3.0 cm mass abuts the superior and inferior. margins. The remaining tissue is variably fatty and fibrous; the fibrous. tissue is firm and nodular in some areas. Sections of tumor and grossly. normal fibrous tissue are harvested for the. rotocol. Matched. sections for histology are as follows: A1-A2: Tumor. A3: Grossly normal fibrous tissue, medial portion of specimen. A4: Medial most margin of specimen. A5-A6: Full thickness cross section. A7-A9: Full thickness cross section. A10-A12: Full thickness cross section. A13-A15: Full thickness cross section. A16-A18: Full thickness cross section. A19-A21: Full thickness cross section. A22-A23: Full thickness cross section. A24-A25: Full thickness cross section. FOR OFFICIAL USE ONLY - PERSONAL DATA - PRIVACY ACT OF. FOR OFFICIAL US% ONLY - PERSONAL DATA - PRIVACY ACT or. Specimen #: GROSS DESCRIPTION (continued) : A26-A27: Full thickness cross section. A28-A30: Full thickness cross section. A31-A33: Full thickness cross section. A34-A35: Full thickness cross section. A36-A38: Full thickness cross section. 38CFNS. B. NEW MEDIAL MARGIN, LEFT BREAST received in formalin labeled with the. patient's name and designated "NEW MEDIAL MARGIN, LEFT BREAST" are two. fragments of yellow/tan fibrofatty soft tissue. The largest fragment. measures 7.5 x 3.0 x 2.0 cm and the smaller tissue fragment measures 4.5 x. 2.5 x 1.3 cm. The specimens are received unoriented. The specimens consist. of lobulated, yellow/tan soft tissue with areas of interdigitating white,. fibrous areas. The outer surface of each specimen is inked in black. Cross. sectioning through both tissue fragments demonstrates homogeneous, yellow,. lobulated soft tissue with interdigitating white, fibrous strands. No. discrete masses or nodules are found. Cassette key: B1-B8: Largest tissue fragment. B9-B15: Smaller tissue fragment. C. SENTINEL LYMPH NODE NUMBER ONE received in formalin labeled with the. patient's name and designated "SENTINAL LYMPH NODE NUMBER ONE" is a 0.7 cm. grossly apparent lymph node and a small amount of adherent fat. A small. portion of the node is harvested for the. protocol. The remaining. lymph node is submitted. D. AXILLARY CONTENTS received in formalin labeled with the patient's name. and designated "AXILLARY CONTENTS" are three fragments of. fibrofatty soft tissue measuring 3.5 x 3.5 x 2.0 cm in aggregate. Sectioning through the specimen demonstrates a mottled, yellow/red. fibrofatty soft tissue. Cassette key: D1-D2 Largest tissue fragment. D3: Second largest tissue fragment. D4: Remaining tissue fragment. FOR OFFICIAL USE ONLY - PERSONAL DATA - PRIVACY A<.

expanded version (tokens=1819) : 
 The breast pathology report provides information about a 9-grade comedo-type invasive carcinoma and high-grade intraductal carcinoma in the left breast lumpectomy. The tumor involved the inferior, superior, and anterior margins, including the new medial margin biopsy, and the lymphatic system with the biopsied sentinel lymph node #1 being positive for metastatic carcinoma. The report indicates that no malignancy was found in the axillary contents biopsy. 

The report also mentions a weakly HER2 positive result by immunohistochemistry. However, the previously conducted FISH analysis revealed no amplification. There is a pending special stain result that is not provided in the report. 

Further, the report states an AJCC pathological staging of pT2 pN1c pMX. The gross description includes information on a poorly differentiated mass measuring 3.0 cm in diameter, and at least two well-circumscribed masses in the left breast lumpectomy. The largest well-circumscribed mass measured 1.2 cm in greatest dimension.  

The report mentions areas of necrosis or tumor infiltrating lymphocytes. It provides information on the histological grade, which is Bloom-Richardson grade 9 (3+3+3), and the nuclear grade. Calcification was also noted on the specimen radiograph. 

Regarding receptor status, further testing might be necessary, as the report only mentions a HER2 result but not ER/PR. Finally, the report mentions

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2001) : 
 Breast lumpectomy resulted in 9-grade infiltrating and intraductal carcinoma, including the new medial margin biopsy. Sentinel lymph node biopsy showed metastatic carcinoma, and axillary contents biopsy was negative for malignancy. AJCC pathological staging is pT2 pN1c. HER2 staining was weakly positive but not amplified by FISH analysis. Histological grade is Bloom-Richardson 9 and a poorly differentiated mass (3cm) with well-circumscribed masses were found. No mention of tumor infiltrating lymphocytes or necrosis. Receptor status is not provided beyond HER2 results, and further testing might be necessary.

