prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Final Surgical Pathology Report. Procedure: Diagnosis. A. Lymph nodes, left axillary sentinel, excision -. Metastatic carcinoma in two of two (2/2) lymph nodes in this part. B. Breast, right, excision -. Invasive lobular carcinoma, 0.5 cm in greatest dimension (see. microscopic description, including for prognostic marker results) . Lobular carcinoma-in-situ. Fibrocystic changes, with microcalcifications present. Skin, nipple, and deep margin negative for tumor. C. Breast, left, excision -. Invasive lobular carcinoma, forming a 3.2 cm in greatest dimension. mass, with additional scattered foci of invasive lobular carcinoma. present. Invasive lobular carcinoma present at least very near (<1 mm from), and. possibly at, the deep margin in the separate foci. Skin and nipple negative for malignancy. Lobular carcinoma-in-situ. Biopsy site changes. Fibrocystic changes, with microcalcifications present. D. Lymph nodes, left axillary, excision. Metastatic carcinoma in nineteen of twenty-two (19/22) lymph nodes in. this part, including with metastatic carcinoma in the superior-most. lymph node. Microscopic Description: A,D. There is metastatic carcinoma in two of two (2/2) sentinel lymph. nodes in part A, and in nineteen of twenty-two (19/22) lymph nodes in. part D. Thus overall in this case, there is metastatic carcinoma in. twenty-one of twenty-four (21/24) lymph nodes (pN3a) There is. extracapsular extension. The largest involved lymph node is one of the. sentinel lymph nodes, 2.5 cm in greatest dimension. The largest lymph. node in part D is negative for tumor. There is metastatic carcinoma in. the superior-most lymph node in part D. Please note that in addition. to examining H&E stained sections, immunostains with antibodies to. keratin (AE1-AE3) were examined on representative blocks in both parts. to aid in assessment. B. The following template summarizes the findings in this part: Invasive carcinoma: Present. Histologic type: Invasive lobular carcinoma, identified. incidentally in block B4. Histologic grade : Overall grade: 2. Architectural score: 3. Nuclear score: 2. Mitotic score: 1. Greatest dimension (pT) : slightly >0.5 cm (pT1b). Specimen margins: Negative. Vessel invasion: Not identified. Nipple: Negative for tumor. Invasion of skin or chest wall: Not identified. Ductal carcinoma in situ: Not identified. Description of non-tumorous 'breast: Fibrocystic changes, with. microcalcifications present. Comments: There is also lobular carcinoma-in-situ present. Please note. that immunostains with antibodies to p63, keratin (AE1-AE3), and. e-cadherin were examined on representative blocks to aid in assessment. Distant metastasis (pM) : Not applicable. Breast prognostic marker results. Estrogen receptor: 80% / moderate intensity. Progesterone receptor: 5% / weak intensity. Her2 by IHC: 1+. Interpretation. Estrogen receptor: Positive. Progesterone receptor: Weakly positive. Her2 by IHC: Negative for Her2 expression. Comments. Fixation time : 30:00. Cold ischemia time: 0:30. The analyzed tissue met quality requirements of the ASCO/CAP guidelines. for Her2 testing. Control materials stained appropriately. Based on data collected in our laboratory and reported in the. literature we recommend FISH analysis for Her2 in cases that stain with. intermediate intensity by immunohistochemistry. Prognostic markers were done by immunohistochemical stain on paraffin. sections from 10% neutral buffered formalin fixed tissue using. antibodies on a Benchmark automated stainer. The Her2 antibody is clone 4B5 and has been approved by the FDA as an. aid in the assessment of breast cancer patients for whom Herceptin. treatment is considered. This laboratory meets the test validation and quality assurance. requirements of the ASCO/CAP guidelines for Her2, ER and PR testing for. carcinoma of the breast. C. The following template summarizes the findings in this part: Invasive carcinoma: Present. Histologic type: Invasive lobular carcinoma. Invasive lobular. carcinoma is identified comprising the main mass lesion, as well as in. multiple additional foci in random sections of this breast (blocks C7,. C8, C10, C11). Histologic grade: Overall grade: 2. Architectural score: 3. Nuclear score: 2. Mitotic score: 1. Greatest dimension (pT) : The main mass lesion is 3.2 cm in. greatest dimension (pT2). Specimen margins: Although the margins surrounding the main mass. lesion are negative, tumor in the additional foci of invasive lobular. carcinoma is present at least very near (<1 mm from). and possibly at,. the deep margin, with fragmentation hindering assessment. Vessel invasion: Not identified. Nipple: Negative for tumor. Invasion of skin or chest wall: Not identified. Ductal carcinoma in situ: Not identified. Description of non-tumorous breast: Fibrocystic changes, with. microcalcifications present. Biopsy site changes. Comments: There is also lobular carcinoma-in-situ present. Please note. that immunostains with antibodies to keratin (AE1-AE3), and e-cadherin. were examined on representative blocks to aid in assessment. Distant metastasis (pM) : Not applicable. Prognostic markers: Previously performed. Note: have reviewed this case. [A few of the antibodies used in our laboratory may be classified as. analyte specific reagents. These antibodies are monitored and. controlled in our laboratory and their performance for in vitro. diagnosis is well described in the medical literature. They have not. been cleared or approved by the FDA.]. Specimen. A. Left axillary sentinel node. B. Right breast. C. Left breast. D. Left axillary contents. Clinical Information. CLINICAL HISTORY: yo white female with invasive lobular cancer left. breast. Intraoperative Consultation. A. Metastatic carcinoma present. Gross Description. A. Received fresh in a container labeled "left axillary sentinel node". is a portion of tissue which is tan-yellow and fatty externally. On. palpation, it appears to consist of two adherent lymph nodes, spanning. an area 2.5 x 1 X 0.5 cm and 1.8 x 1 X 0.4 cm. On cut surface, both. vary from soft and tan to yellow, to firmer and tan-white. The. specimen is entirely submitted for frozen section in two blocks, with. one lymph node per block. B. Received fresh (excised at. placed in. formalin at. in a container labeled "right breast" is a 21 cm from. superior to inferior x 18 cm from medial to lateral x 3.2 cm from. anterior to posterior soft tan-yellow mastectomy specimen, with an. orienting suture present. On the anterior surface there is a 7. X 4.4. cm. tan-white skin ellipse, with a centrally located 1.3 X 1.3 x 1 cm. nipple. The intact deep margin is inked, and the specimen is serially. sectioned. On cut surface, the specimen consists of interspersed. yellow adipose tissue and tan tissue, without focal lesion. RS-10,. following fixation. BLOCK SUMMARY: B1,B2 - upper outer quadrant; B3,B - upper inner. quadrant; 85,B6 - lower inner quadrant; B7,B8 - lower outer quadrant;. B9 - central breast; B10 - nipple. C. Received fresh (excised at. placed in. formalin at. in a container labeled "left breast" is a 20.5 cm. from superior to inferior x 18.8 cm from medial to lateral x 3.2 cm. from anterior to posterior soft tan-yellow mastectomy specimen, with an. orienting suture present. On the anterior surface there is a 7 X 5 cm. tan-white skin ellipse, with a centrally located 1.2 x 1.2 x 0.5 cm. nipple. The intact deep margin is inked, and the specimen is serially. sectioned. There is a circumscribed 3.2 x 2.9 X 1.8 cm rubbery. tan-white mass within the upper outer quadrant. The lesion is 1.1 cm. from the deep margin, and 1.3 cm from the anterior surface, which is. subsequently inked blue. The specimen away from the nodule consists of. interspersed yellow adipose tissue and tan tissue, without additional. focal lesion. RS-12, following fixation. BLOCK SUMMARY: C1-C3 - tumor to anterior surface; C4,C5 - tumor to deep. margin; C6 - central tumor; C7 - upper outer quadrant; C8 - upper. inner quadrant; C9 - lower inner quadrant; C10 - lower outer quadrant;. C11 - central breast; C12 - nipple. D. Received fresh in a container labeled "left axillary contents" is a. 6.5 x 6.3 x 2.4 cm aggregate of yellow lobular fatty tissue which has a. suture designating superior axilla. Dissection of the specimen reveals. multiple lymph nodes, up to 3.5 cm in greatest dimension. RS-9,. following fixation, with all lymph nodes submitted, from superior to. inferior, with the superior-most lymph node in block D1, four lymph. nodes in block D2, five lymph nodes in block D3, three lymph nodes in. block D4, one sectioned lymph node in blocks D5 & D6, four lymph nodes. in block D7, one lymph node in block D8, and three lymph nodes in block. D9.

expanded version (tokens=2538) : 
 Histological Classification:
- Invasive lobular carcinoma in the right breast, forming a 0.5 cm mass
- Invasive lobular carcinoma in the left breast, forming a 3.2 cm mass with additional scattered foci
- Lobular carcinoma in situ in both breasts
- Metastatic adenocarcinoma in 21 of 24 lymph nodes (pN3a)

Subtype:
- LumA

Necrosis:
- Not mentioned

Tumor infiltrating lymphocytes:
- Not mentioned

Histological Grade:
- Architectural score: 3
- Nuclear score: 2
- Mitotic score: 1
- Overall grade: 2 for both breasts

Nuclear Grade:
- Not mentioned

Lymphovascular Invasion:
- Not identified

Calcification:
- Fibrocystic changes with microcalcifications present in both breasts

Receptor Status:
- Estrogen receptor: 80% / moderate intensity
- Progesterone receptor: 5% / weak intensity
- HER2: Negative by IHC

Ancillary Testing:
- Immunostains with antibodies to keratin (AE1-AE3), p63, e-cadherin, and HER2 by FISH analysis recommended for cases with intermediate HER2 expression by IHC.

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2719) : 
 Report: LumA subtype, invasive lobular carcinoma identified in both breasts, with additional foci noted in the left breast. Lobular carcinoma-in-situ present in both breasts. Metastatic adenocarcinoma present in 21 of 24 axillary lymph nodes. Necrosis and tumor infiltrating lymphocytes not identified. No lymphovascular invasion found. Architectural score 3, nuclear score 2, mitotic score 1, with overall grade 2 for both breasts. Estrogen receptor positive at 80%, progesterone receptor weakly positive at 5%, HER2 negative by IHC (recommended for further HER2 testing).

