prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumB, Provider Group : Date of Service: Date Received: FINAL SURGICAL PATHOLOGY REPORT. Diagnosis: A. - F. RIGHT BREAST AND AXILLARY LYMPH NODES, MASTECTOMY, SENTINEL. LYMPH NODE BIOPSIES, AND AXILLARY LYMPH NODE DISSECTION: - Multifocal invasive ductal carcinoma, Nottingham grades 2-3. See comment. - Largest tumor nodule: 1.5 cm in diameter (6 o'clock aspect). - Two smaller nodules: 0.6 and 0.8 cm (7-8 o'clock aspect). - Ductal carcinoma in situ (DCIS), high nuclear grade, solid type. - DCIS comprises less than 10% of biopsy tissue volume, and is associated. with all three invasive tumor nodules. - Mastectomy margins are free of tumor. - Carcinoma is 3 cm from the inferior margin and is at least 6 cm from. all other margins. Metastatic carcinoma in three of fifteen lymph nodes (3/15). - Largest metastatic focus: 0.9 cm in diameter. - Extranodal extension present. - Positive lymph nodes are sentinel lymph nodes #2, #3, and #4. PATHOLOGIC TUMOR STAGING SYNOPSIS: Type and grade (invasive): Invasive ductal carcinoma, Nottingham grade 2-3. Type and grade (in situ): DCIS, high-nuclear grade. Primary tumor: pT1c(m). Regional lymph nodes: pN1c. Distant metastasis: Not applicable. Stage: IIA. Lymphovascular invasion: Indeterminate. Margin status: Negative. COMMENT: The three foci of invasive carcinoma have similar histologic features,. although the tumor grade is somewhat variable in the largest tumor nodule, where. there is a variable rate of mitosis, and nuclear pleomorphism ranging from. intermediate to high-grade. The smaller tumor nodules contain high-grade malignant. Printed: This report continues. Acct No. -. Pathology - Page 1/6. Page 1 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. epithelial cells arranged in solid sheets with frequent mitoses, compatible with. Nottingham grade 3. There is enough morphologic similarity between three nodules. to suggest that they have a common origin. Intradepartmental consultation: concurs with this impression. Invasive Breast Cancer Tumor Staging Information. AJCC Cancer Staging Handbook, 7th Ed. and CAP Protocol (revised June 2012). Previous pathology specimens: his report continues (FINAL). Printed: MR No. -. lage 2 Doc# 1. Pathology - Page 2/6. SPECIMEN IDENTIFICATION. Procedure/specimen type: Modified radical mastectomy. Laterality: Right. Lymph node sampling: Sentinel lymph node biopsies followed by lymph. node dissection. INVASIVE CARCINOMA TUMOR CHARACTERISTICS. Histologic type: Invasive ductal carcinoma (multifocal). Tumor sites: 6:00-8:00. Tumor size: Largest tumor nodule 1.5 cm. Tumor focality: Multifocal. Histologic grade (Nottingham Score): 2-3 of 3. Tubule formation: 3 of 3. Nuclear pleomorphism: 2-3 of 3. Mitotic rate: 2-3 of 3 (variable mitotic rate). Lymphovascular invasion: Indeterminate. Macroscopic and microscopic extent of tumor: No skin or chest wall invasion identified. DUCTAL CARCINOMA IN SITU (DCIS): Present in association with three invasive tumor. nodules. MARGINS. Invasive carcinoma: Negative. Ductal carcinoma in situ: Negative. LYMPH NODES. Total lymph nodes examined. 15. Number of lymph nodes involved. 3. Size of largest metastatic deposit: 0.9 cm. Extranodal extension: Present. PATHOLOGIC STAGING: Primary Tumor (pT): pTic(m). Regional lymph nodes (pN): pN1a. Distant metastasis (pM): Not applicable. AJCC Stage: IIA. ANCILLARY STUDIES: on 2. previous biopsies (additional HER2 studies. pending, to be reported in an addendum). Estrogen receptor: 85-96% positive cells, strong intensity. Progesterone receptor: 0% positive cells. HER2: Additional studies pending, to be reported in an. addendum. Printed: This report continues. Acct No. Pathology - Page 3/6. Page 3 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. Ki-67: Variable, previously reported 7-69%. Source of Specimen: A. Sentinel lymph node;#1--. right axillary. B. Sentinel lymph node;#2--. right axillary. C. Sentinel lymph node;#3-. right axillary. D. Sentinel lymph node;#4. right axillary. E. Breast surgical;right. F. Axillary nodes right. Clinical History/Operative Dx: Right breast cancer. Intraoperative Diagnosis: A. Sentinel node #1. - diagnosis: Negative for carcinoma. B. Sentinel node #2. - diagnosis: Rare atypical cells, suspicious for carcinoma. (Defer to. permanents). D. Sentinel node #4. and. - diagnosis: Positive for carcinoma. The intraoperative interpretation(s) was/were performed and rendered at. Gross Description: A. Part A is designated as sentinel node #1. right axilla, touch prep. Initially received in the fresh. state four frozen section/touch prep evaluation is a 1.0 x 0.8 x 0.6 cm piece of red-tan soft tissue. Examination reveals a 0.7 x 0.6 x 0.5 cm lymph node. The cut surfaces are fatty and rubbery, pink and. tan. Two touch imprint slides are prepared for microscopic evaluation. The lymph node is entirely. Printed: This report continues. Acct No. Pathology - Page 4/6. age 4 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. submitted for routine histology in A1 with a sentinel node protocol performed. B. Part B is sentinel node #2. Initially received in the fresh state for touch prep/frozen section. evaluation is a 1.5 X 1.2 x 1. 0 cm yellow-tan portion of tissue. Examination reveals a 0.8 x 0.6 x 0.6 cm. lymph node. Sectioning demonstrates a rubbery, pink and tan cut surfaces. Two touch imprint slides are. submitted for microscopic evaluation. The Ivmph node is entirely submitted for routine histology in B1. with a sentinel node protocol performed. C. Part C designated as sentinel node #3. right axillary. Received in formalin is a 1.5 x 1.5 x 0.7. cm fragment of fat. Examination reveals two possible apparent lymph nodes, 0.8 x 0.6 x 0.4 cm each. The. lymph node is serially sectioned and entirely submitted for microscopic evaluation in C1 with a sentinel. lymph node protocol performed. D. Part D is designated as sentinel node #4. right axillary. Initially received in the fresh state for. frozen section/touch imprint evaluation is a 1.5 X 1.2x 1.0 cm yellow-green portion of fatty soft tissue. Examination reveals a 1.0 x 0.8 x 0.8 cm dense, pink-gray lymph node. Two touch imprint slides and a. representative section is submitted for frozen section evaluation. The residual frozen tissue is submitted in. D1 for permanent sections and the touch imprint aspect of the lymph node is submitted in D2 for. permanent sections with a sentinel lymph node protocol performed. E. Received fresh labeled "right breast." Sutures present for orientation purposes. A portion of tumor is. submitted for. Laterality: Right. Specimen: Mastectomy. Size of mastectomy: (M-L x S-I x A-P): 23.5 x 19x 5 cm. Axillary tail: Not present. Skin: 24 x 18 cm, pigmented skin. Nipple/areola: Yes, center of skin. Specimen weight: 971 grams. Ink code: Blue - superior-anterior, orange - inferior-anterior, black - deep. Stabs: Total # 11, M-I= 1, L-S= 11. Nipple in slab #6. Time of resection: Time placed into formalin: Time out of formalin: Lesion 1: Biopsy site present. Size: 1.5 x 1.4 x 0.8 cm, stellate, gray-white, firm mass. Location: 6:00. Involves slabs # 3-4. Distance to nearest margin(s): 3 cm from inferior margin, 6 cm from deep margin. Lesion #2: Biopsy site present. Size: 0.8 x 0.5 x 0.5 cm. Location: 7:00. Involves slabs #2-3. Distance to nearest margin(s): 6 cm from inferior. Printed: This report continues (FINAL). MR No. -. Acct No. -. Pathology - Page 5/6. - Page 5 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. Lesion #3: No biopsy site present. Size: 0.6 x 0.6 x 0.5 cm. Location: 7:00. Involves slabs #4. Distance to nearest margin(s): 5 cm from inferior. Non-lesional breast: Fibrofatty breast tissue. Cassette summary: E1) smallest 7:00 tumor, previously biopsied (portion of the small tumor submitted for. E2-E4) largest 6:00 lesion,. E5) central breast tissue,. E6-E7) lateral breast tissue,. E8) nipple/subareolar breast tissue,. E9) representative breast tissue,. E10-E11) fibrous tissue medial to largest tumor,. E12) representative medial breast tissue,. E13) mass #3, 7:00,. E14-E15) central posterior breast tissue. F. Part F is which axillary nodes, right. Received in formalin is an 83 gram partially tattered portion of. yellow-tan fatty soft tissue, 13.0 x 9.0 x 2.6 cm. Examination reveals eleven lymph nodes ranging from 0.2. cm to 1.9 X 1.4 x 1.2 cm in greatest dimension. The lymph nodes are entirely submitted for microscopic. evaluation. Cassette summary: F1) four lymph nodes,. Ne. F2) four lymph nodes,. F3) one lymph node, bisected,. F4) one lymph node, bisected,. F5-F6) largest lymph node, serially sectioned. Microscopic Description: A. - C. Immunohistochemical stain: CK OSCAR, showing focal metastatic carcinoma in specimens B and. C. D. Immunohistochemical stain: CK OSCAR, highlighting metastatic carcinoma. HER2 - results pending, to. be reported in an addendum. E. Immunohistochemical stain: HER2, to be reported in an addendum. F. Microscopic sections have been examined. The microscopic findings are reflected in the diagnosis. rendered. Printed: END OF REPORT (FINAL). MR No. -. Acct No. 'atient Name -. Pathology - Page 6/6. uge 6 Doc# 1.

expanded version (tokens=2913) : 
 The breast pathology report gives the following information: 

1. Histological classification:
- Multifocal invasive ductal carcinoma, Nottingham grades 2-3.
- Ductal carcinoma in situ (DCIS), high nuclear grade, solid type.

2. Subtype:
- The report mentions LumB subtype, which is a subtype of estrogen receptor (ER) positive breast cancer. 

3. Necrosis:
- There is no mention of necrosis in the report.

4. Tumor infiltrating lymphocytes:
- No specific mention of tumor infiltrating lymphocytes is made in the report.

5. Histological grade:
- Nottingham grades 2-3 for invasive ductal carcinoma.
- High nuclear grade for DCIS.

6. Nuclear grade:
- The largest invasive tumor nodule shows a variable rate of mitosis and nuclear pleomorphism ranging from intermediate to high-grade.

7. Lymphovascular invasion:
- The report states that lymphovascular invasion is indeterminate.

8. Calcification:
- There is no mention of calcification in the report.

9. Receptor status:
- Estrogen receptor: 85-96% positive cells, strong intensity.
- Progesterone receptor: 0% positive cells.
- HER2: Additional studies pending, to be reported in an addendum.

10. IHC and other ancillary testing results:
- CK OSCAR stain showed focal metastatic carcinoma in specimens B and C.
- Additional HER2 studies are

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3078) : 
 Report shows LumB subtype of ER-positive breast cancer with multifocal invasive ductal carcinoma and DCIS. Intermediate to high-grade nuclear pleomorphism found in the largest invasive tumor nodule. Three lymph nodes out of fifteen have metastatic carcinoma with extranodal extension present. Estrogen receptor status is 85-96% positive, while progesterone receptor status is negative, HER2 status pending. No notable necrosis, tumor infiltrating lymphocytes or calcification mentioned. Lymphovascular invasion indeterminate and mastectomy margins clear of tumor. Overall stage IIA disease.

