prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - FINAL DIAGNOSIS: PART 1: SENTINEL LYMPH NODE #1, LEFT AXILLA, BIOPSY -. ISOLATED TUMOR CELLS IDENTIFIED IN ONE OF ONE LYMPH NODE (1/1) (See comment). PART 2: SENTINEL LYMPH NODE #2, LEFT AXILLA, BIOPSY -. ONE BENIGN LYMPM NODE (0/1). PART 3: BREAST, LEFT, TOTAL MASTECTOMY (380.8 GRAM3) -. A. INVASIVE LOBULAR CARCINOMA, CLASSICAL TYPE, NOTTINGHAM GRADE II (TUBULE FORMATION 3,. NUCLEAR PLEOMORPHISM 2, MITOTIC ACTIVITY 2; TOTAL SCORE: 7/9). B. THE INVASIVE TUMOR MEASURES 2.8 CM IN GREATEST DIMENSION. C. LOBULAR CARCINOMA IN SITU (LCIS), CLASSICAL TYPE, IS ALSO IDENTIFIED IN THE UPPER OUTER. QUADRANT, LOWER OUTER QUADRANT, AND LOWER INNER QUADRANT, WITH PAGETOID EXTENSION. INTO DUCTS. D. LYMPHOVASCULAR. SPACE INVASION IS IDENTIFIED. E. RESECTION MARGINS ARE NEGATIVE FOR CARCINOMA; INVASIVE CARCINOMA IS 0.25 CM FROM THE. NEAREST POSTERIOR MARGIN. F. THE INVASIVE CARCINOMA IS LOCATED IN THE UPPER OUTER QUADRANT. G. NIPPLE IS NEGATIVE FOR TUMOR. H. THE RETICULAR DERMIS OF THE SKIN IS INVOLVED BY INVASIVE CARCINOMA BY DIRECT EXTENSION. 1. THE SKIN SHOWS A CAPILLARY HEMANGIOMA. J. ATYPICAL LOBULAR HYPERPLASIA. K. CALCIFICATIONS ARE ASSOCIATED WITH BENIGN BREAST PARENCHYMA. L. THE NON-NEOPLASTIC BREAST SHOWS FIBROCYSTIC CHANG WITH APOCRINE METAPLASIA AND. DUCTAL EPITHELIAL HYPERPLASIA. M. PREVIOUS BIOPSY SITE CHANGES ARE IDENTIFIED. N. THE INVASIVE TUMOR CELLS ARE POSITIVE FOR ESTROGEN AND PROGESTERONE RECEPTORS ANO. EQUIVOCAL FOR HER-2, AS PER PREVIOUS PATHOLOGY REPORT. (see comment). COMMENT: Part 1: On the AE1/AE3 immunohistochemicat stain, rare aubcapsular positive cells are identified, which could not be. identified on H&E stain. Less than 10 scattered positive subcapsular cells are Identified. Part 3: HER-2 studies will be repeated with an addendum to follow. Blocks 1FS1, 1952, 2791,. Antibody/Antigen. AE1/AE3. Negative. CASE SYNOPSIS: SYNOPTIC . PRIMARY INVASIVE CARCINOMA OF BREAST. LATERALITY: Left. PROCEDURE: Simple mastectomy. Upper outer quadrant. SIZE OF TUMOR: Maximum dimension invasive component: 28 mm. MULTICENTRICITY/MULTIFOCALITY OF INVASIVE FOCI: TUMOR TYPE (Invasive component): Infiltrating lobular carcinoma. HISTOLOGIC TYPE: Classical. NOTTINGHAM SCORE: Nuclear grade: 2. Tubule formation: 3. Mitotic activity score: 2. Total Nottingham score: 7. Nottingham grade (1, 2, 3): 2. ANGIOLYMPHATIC INVASION: DERMAL LYMPHATIC INVASION: CALCIFICATION: Yes, benign zones. TUMOR TYPE, IN SITU: LCIS. SURGICAL MARGINS INVOLVED BY INVASIVE COMPONENT: Distance of Invasive tumor to closest margin: 2.5 mm. PAGETS DISEASE OF NIPPLE: LYMPH NODES POSITIVE: 1. LYMPH NODES EXAMINED: 2. METHOD(S) OF LYMPH NODE EXAMINATION: H/E stain. Keratin stain. SKIN INVOLVED (ULCERATION): NON-NEOPLASTIC BREAST TISSUE: ALH, FCD. T STAGE, PATHOLOGIC: pT2. N STAGE MODIFIER: (sn). N STAGE, PATHOLOGIC: M STAGE: Not applicable. ESTROGEN RECEPTORS: positive. PROGESTERONE RECEPTORS: positive. HER2/NEU: HER2/NEU (FISH): Equivocal. Addendum. BREAST TUMOR IMMUNOHISTOLOGY RESULTS. HER-2/NEU IMMUNOHISTOCHEMISTRY [NEGATIVE:0,1+ EQUIVOCAL: 2+; POSITIVE: 3+]. SCORE. HER-2/NEU. Equivocal. 2+. NOTE (for 2+ cases): HER2 FISH is being performed and the results will be subsequently reported in an addendum. SPECIAL PROCEDURES: FISH (PCL). Interpretation. nucish(D17Z1x2-3,ERBB2x2-6)(40]. Interphase FISH analysis is equivocal for HER-2/NEU gene amplification. Fluorescence in situ hybridization (FISH) analysis was performed on a formalin-fixed Block 3A (left breast total mastectomy) using. the DNA probe for the HER-2/NEU gene 1. An adequate number of invasive tumor cells were present and. evaluated by two independent observers. The ratio of HER-2/NEU signals (ERBB2) to chromosome 17 centromere signals. (D17Z1) was determined to be 1.93. A ratio of greater than 2.2 is considered to be amplified with ratios of 1.80 to 2.20 in the. equivocal range; therefore, this specimen is equivocal for HER2/NEU gene amplification. The average number of. HER-2/NEU signais per cell was 4.25. The average number of signals for the chromosome 17 centromere was 2.20. Concurrent. positive and negative control specimens showed the expected results. This FISH test is performed using a modification of the Vysis FDA approved PathVysion HER-2 DNA Probe Kit (1:2 LSI HER-2/neu. /. CEP17 probe : T-denhyb-2 buffer). This FISH test was developed and its performance determined by the. Pursuant to the requirements of CLIA '88, this laboratory has established and verified the test's. accuracy and precision.

expanded version (tokens=1877) : 
 Histological classification: 
- Part 1: Isolated tumor cells identified in one of one lymph node. 
- Part 2: One benign lymph node. 
- Part 3: 
A. Invasive lobular carcinoma, classical type, Nottingham grade II (tubule formation 3, nuclear pleomorphism 2, mitotic activity 2; total score: 7/9). 
B. Lobular carcinoma in situ (LCIS), classical type, identified in upper outer quadrant, lower outer quadrant, and lower inner quadrant, with pagetoid extension into ducts. 
C. Lymphovascular space invasion is identified. 
D. Resection margins are negative for carcinoma; invasive carcinoma is 0.25 cm from the nearest posterior margin. 
E. The invasive carcinoma is located in the upper outer quadrant. 
F. The nipple is negative for tumor. 
G. The reticular dermis of the skin is involved by invasive carcinoma by direct extension. 
H. The skin shows a capillary hemangioma. 
J. Atypical lobular hyperplasia. 
K. Calcifications are associated with benign breast parenchyma. 
L. The non-neoplastic breast shows fibrocystic changes with apocrine metaplasia and ductal epithelial hyperplasia. 
M. Previous biopsy site changes are identified. 

Subtype: 
- Invasive lobular carcinoma, classical type. 
-

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2048) : 
 Report: The breast pathology report reveals the presence of isolated tumor cells and one benign lymph node. Invasive lobular carcinoma, classical type with pagetoid extension into ducts, lymphovascular space invasion, and negative margins is identified in the upper outer quadrant. The tumor cells are positive for estrogen and progesterone receptors with equivocal HER-2 receptor status. Atypical lobular hyperplasia is also present along with calcifications associated with benign breast parenchyma. The previous biopsy site changes are identified, and FISH analysis is equivocal for HER-2/NEU gene amplification.

