prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Normal, FINAL DIAGNOSIS: PART 1: BREAST, LEFT, SEGMENTAL MASTECTOMY AT 2 O'CLOCK -. A. INVASIVE LOBULAR CARCINOMA, CLASSICAL TYPE. B. NOTTINGHAM GRADE 2 (TUBULE FORMATION 3, NUCLEAR ATYPIA 2, MITOTIC ACTIVITY 1; TOTAL SCORE. 6/9). C. INVASIVE TUMOR MEASURES 1.6 CM IN LARGEST DIMENSION (GROSS MEASUREMENT). D. NO LYMPHOVASCULAR IDENTIFIED. E. INVASIVE TUMOR IS 1 MM TO THE CLOSEST ANTERIOR MARGIN. F. LOBULAR CARCINOMA IN-SITU AND ATYPICAL LOBULAR HYPERPLASIA. G. NON-NEOPLASTIC BREAST TISSUE SHOWING FIBROCYSTIC CHANGE, SCLEROSING ADENOSIS,. AND. MICROCALCIFICATIONS. H. BIOPSY SITE CHANGE. I. INVASIVE TUMOR POSITIVE FOR ER, PR AND EQUIVOCAL FOR HER-2/NEU. PART 2: AXILLARY SENTINEL LYMPH NODE #1, LEFT, BIOPSY -. FIVE LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/5). PART 3: AXILLARY SENTINEL LYMPH NODE #2, LEFT, BIOPSY -. ONE LYMPH NODE, NEGATIVE FOR METASTATIC CARCINOMA (0/1). PART 4: AXILLARY NON-SENTINEL LYMPH NODE TISSUE, LEFT, BIOPSY -. ONE LYMPH NODE, NEGATIVE FOR METASTATIC CARCINOMA (0/1). CASE SYNOPSIS: SYNOPTIC - PRIMARY INVASIVE CARCINOMA OF BREAST. LATERALITY: Left. PROCEDURE: Segmental. Clock position:2. SIZE OF TUMOR: Maximum dimension invasive component: 16 mm. MULTICENTRICITY/MULTIFOCALTY OF INVASIVE FOCI: TUMOR TYPE (invasive component): Infiltrating lobular carcinoma. Classical. HISTOLOGIC TYPE: NOTTINGHAM SCORE: Nuclear grade: 2. Tubule formation: 3. Mitotic activity score: 1. Total Nottingham score: 6. Nottingham grade (1, 2, 3): 2. ANGIOLYMPHATIC INVASION: DERMAL LYMPHATIC INVASION: Not applicable. CALCIFICATION: Yes, benign zones. TUMOR TYPE, IN SITU: LCIS. SURGICAL MARGINS INVOLVED BY INVASIVE COMPONENT: LYMPH NODES POSITIVE: 0. LYMPH NODES EXAMINED: 7. METHOD(S) OF LYMPH NODE EXAMINATION: H/E stain. NON-NEOPLASTIC BREAST TISSUE: ALH, FCD. T STAGE, PATHOLOGIC: pT1c. N STAGE, PATHOLOGIC: pNO. M STAGE: Not applicable. ESTROGEN RECEPTORS: positive, H-score: 180. PROGESTERONE RECEPTORS: positive, H-score: 75. HER2/NEU: 2+. Addendum. Part #1: HER-2/NEU IMMUNOHISTOCHEMISTRY [NEGATIVE:0,1+ EQUIVOCAL: 2+; POSITIVE: 3+]. SCORE. HER-2/NEU. Equivocal. 2+. NOTE: HER2 FISH is being performed and the results will be subsequently reported. HER2 IMMUNOHISTOCHEMISTRY TEST DETAILS: Using appropriate formalin fixed (8 - 96 hours). controls and tissue test. block, 4B5 antibody clone is used as part of FDA approved. and. interpreted as follows: Score 0 (negative) = No staining is observed or membrane staining is observed in less than 10% of the. tumor cells. Score 1+ (negative) = A faint/barely perceptible membrane staining is detected in more than 10% of the tumor cells. The cells are only stained in part of their membrane. Score 2+ (equivocal) = A weak to moderate complete membrane staining is. observed in more than 10% of the tumor cells. This score requires reflex testing by FISH. Score 3+ (positive) = A strong complete. membrane staining is observed in more than 30% of the tumor cells. SPECIAL PROCEDURES: FISH. Interpretation. nucish(D17Z1x2-5,ERBB2x2-8)[40]. No amplification of the HER-2/NEU gene was seen by interphase FISH analysis. Fluorescence in situ hybridization (FISH) analysis was performed on a formalin-fixed Block 1H (left segmental mastectomy @ 2:00). using the DNA probe for the HER-2/NEU gene. An adequate number of invasive tumor cells were. present and evaluated by two independent observers. The ratio of HER-2/NEU signals (ERBB2) to chromosome 17 centromere. signals (D17Z1) was determined to be 1.34. A ratio of greater than 2.2 is considered to be amplified; therefore, this specimen is. not amplified. Although amplification was not seen, many of the cells exhibited 3 or more signals for both the HER-2/NEU gene. and for the chromosome 17 centromere. This may be indicative of either polyploidy or aneuploidy for chromosome 17. The. average number of HER-2/NEU signals per cell was 3.26. The average number of signals for the chromosome 17 centromere was. 2.44. Concurrent positive and negative control specimens showed the expected results. This FISH test is performed using a modification of the. FDA approved. HER-2 DNA Probe Kit (1:2 LSI HER-2/neu. / CEP17 probe : T-denhyb-2 buffer). This FISH test was developed and its performance determined by the. Pursuant to the requirements of CLIA '88, this laboratory has established and verified the test's. accuracy and precision.

expanded version (tokens=1787) : 
 The report includes the following information: 

1. Histological classification: 
    - Invasive lobular carcinoma (classical type)
    - Lobular carcinoma in-situ
    - Atypical lobular hyperplasia
    - Non-neoplastic breast tissue showing fibrocystic change, sclerosing adenosis, and microcalcifications

2. Tumor characteristics: 
    - Nottingham grade 2 (tubule formation 3, nuclear atypia 2, mitotic activity 1; total score 6/9)
    - Invasive tumor measures 1.6 cm in largest dimension
    - No lymphovascular invasion identified
    - Invasive tumor is 1 mm to the closest anterior margin
    - ER and PR positive
    - Equivocal for HER-2/NEU

3. Ancillary testing: 
    - HER-2/NEU FISH performed and not amplified 
    - Lymph nodes negative for metastatic carcinoma (0/5)
    - T stage, pathologic: pT1c
    - N stage, pathologic: pNO

Overall, the report describes a left breast segmental mastectomy with findings of invasive lobular carcinoma, lobular carcinoma in-situ, and atypical lobular hyperplasia. The tumor is a classical type with a Nottingham grade 2. There is no lymphovascular invasion identified and the surgical margins are clear. The tumor is

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1950) : 
 Left breast segmental mastectomy revealed a 1.6 cm classical type invasive lobular carcinoma, Nottingham grade 2 and ER/PR positive, HER-2/NEU equivocal. The tumor is to the closest anterior margin with no lymphovascular invasion identified. No metastatic carcinoma was found in seven lymph nodes examined pathologically. Lobular carcinoma in-situ and atypical lobular hyperplasia were also present, along with fibrocystic change, sclerosing adenosis, and microcalcifications in non-neoplastic tissue surrounding the tumor.

