prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, SPECIMENS: A. SLN #1. B. SLN #2. C. LEFT BREAST WLE. D. ADDITIONAL LATERAL MARGIN. E. MEDIAL LEFT BREAST TISSUE. F. LATERAL LEFT BREAST TISSUE. G. RIGHT BREAST TISSUE. SPECIMEN(S): A. SLN #1. B. SLN #2. C. LEFT BREAST WLE. D. ADDITIONAL LATERAL MARGIN. E. MEDIAL LEFT BREAST TISSUE. F. LATERAL LEFT BREAST TISSUE. G. RIGHT BREAST TISSUE. GROSS DESCRIPTION: A. SLN #1. Received fresh is a tan pink lymph node 2.0 x 0.8 x 0.7cm. The specimen is sectioned and a touch prep. is taken. Toto A1. B. SLN #2. Received fresh is a tan pink lymph node 0.5 X 0.5 x 0.5cm. The specimen is sectioned and a touch prep. is taken. Toto B1. C. LEFT BREAST WLE. Received fresh is an oriented (short-superior, long-lateral, looped-anterior) 266g, 7.0cm anterior to. posterior, 10.5cm superior to inferior and 12.0cm medial to lateral, lumpectomy with needle localization. wire. The specimen is inked as follows: Anterior-Blue, Posterior-Black, Superior-Red, Inferior-Orange,. Medial-Green, Lateral-Yellow. The specimen is serially sectioned from medial to lateral into 7 slices,. slice 1 being most medial, slice 7 being most lateral to reveal a gray white stellate firm mass 2.6 x 1.8 X. 1.4cm, 1 cm from the closest deep margin in slices 5 and 6. A 0.5 cm nodule is identified, 0.4cm from. the deep margin and 1.5cm from the mass in slice 6. A 0.6 cm nodule is also identified, 0.5cm from the. deep/lateral margin in slice 7. A surgical clip is identified in slice 6. A portion of the specimen is. submmitted for tissue procurement. Representative sections are submitted as follows: C1-C3: medial margin perpendicular from superior to inferior slice 1. C4: superior/deep margin slice 2. C5: slice 2. C6: deep margin slice 2. C7: slice 2. C8: inferior margin slice 2. C9-C10: deep margin slice 3. C11-C13: slice 3 from superior to inferior with C13 inferior margin. C14: deep/inferior margin slice 3. C15-C16: deep margin slice 4. C17-C18: next to mass slice 4. C19-C20: deep margin slice 4. C21: inferior margin slice 4. C22: superior margin slice 5. C23: deep margin slice 5. C24-C26: mass slice 5. C27: anterior margin slice 5. C28: inferior margin slice 5. C29: superior margin slice 6. C30-C31: deep margin slice 6. C32: above mass slice 6. C33: mass slice 6- clip. C34: satellite nodule slice 6. C35: area in between mass and nodule slice 6. C36: inferior margin slice 6. C37: perpendicular sections next to mass, slice 7. C38-C39: nodularity slice 7. As per attached diagram. D. ADDTIONAL LATERAL MARGIN-Stitch at final margin. Received fresh is an oriented 53g fragment of fibrofatty tissue 10.0 x 6.0 X 3.0cm. The new true margin. is inked Blue and the specimen is serially sectioned to reveal grossly unremarkable breast parenchyma. Representative sections are submitted in D1-D10. E. MEDIAL LEFT BREAST TISSUE. Received in formalin is a 321 g, 25 x 9 X 4 cm yellow-tan fibrofatty breast tissue with 17 x 5 cm skin. The breast parenchyma consists primarily of fatty breast tissue with few fibrous areas identified. No. masses or lesions are seen. Representatively submitted in cassettes E1-E5. F. LATERAL LEFT BREAST TISSUE. Received in formalin is a 238 g, 12 x 10 x 2.5 cm yellow-tan fibrofatty breast tissue with 12 x 8 cm skin. On sectioning no masses or lesions are observed. Representative sections are submitted in cassettes. F1-F3. G. RIGHT BREAST TISSUE. Received in formalin and are multiple pieces of yellow-tan fibrofatty breast tissue with the largest portion. having attached tan skin. The specimen weighs 961 g; the intact tissue measures 40 x 11 X 4.5 cm. On. the surface are two irregularly shaped pieces of tan skin measuring 16 cm in length and 6.5 cm in width. and 12 cm in length by 4 cm in width. The skin surface is unremarkable. The detached fibroadipose. tissue in aggregate measures 12.5 X 8.5 x 3.5 cm. On sectioning the specimen is comprised primarily. of adipose tissue. No masses or lesions are observed. Representative sections are submitted in. cassettes G1-G10. DIAGNOSIS: A. SENTINEL LYMPH NODE #1, LEFT AXILLA, BIOPSY: - ONE LYMPH NODE, NEGATIVE FOR CARCINOMA (0/1). B. SENTINEL LYMPH NODE #2, LEFT AXILLA, BIOPSY: - ONE LYMPH NODE, NEGATIVE FOR CARCINOMA (0/1). C. BREAST, LEFT/NEEDLE LOCALIZATION WIDE LOCAL EXCISION: - INVASIVE LOBULAR CARCINOMA, MODERATELY DIFFERENTIATED. (SBR GRADE 2). - TUMOR MEASURES 2.6 CM IN GREATEST DIMENSION. - MARGINS, NEGATIVE FOR CARCINOMA. - LOBULAR CARCINOMA IN SITU. - FOCAL ATYPICAL DUCTAL HYPERPLASIA. - COLUMNAR CELL CHANGE WITH CYTOLOGIC ATYPIA. (FLAT EPITHELIAL ATYPIA). D. BREAST, LEFT, ADDITIONAL LATERAL MARGIN, EXCISION: - BREAST TISSUE, NEGATIVE FOR CARCINOMA. E. BREAST, LEFT, MEDIAL TISSUE, EXCISION: - COLUMNAR CELL CHANGE WITH FOCAL CYTOLOGIC ATYPIA (FLAT. EPITHELIAL ATYPIA), USUAL DUCTAL HYPERPLASIA, AND. FIBROADENOMATOID CHANGE, NEGATIVE FOR CARCINOMA. - SKIN, NEGATIVE FOR CARCINOMA. F. BREAST, LEFT, LATERAL TISSUE, EXCISION: - BREAST TISSUE, NEGATIVE FOR CARCINOMA. G. BREAST, RIGHT, EXCISION: - COLUMNAR CELL CHANGE WITH FOCAL ARCHITECTURAL AND. CYTOLOGIC ATYPIA (FLAT EPITHELIAL ATYPIA) (SEE NOTE). /. - BENIGN SKIN. SYNOPTIC REPORT - BREAST. Specimen Type: Excision. Needle Localization: Yes - For mass. Laterality: Left. Invasive Tumor: Present. Multifocality: No. WHO CLASSIFICATION. Invasive lobular carcinoma 8520/3. Tumor size: 2.6cm. Tumor Site: 3:00. Margins: Negative. Distance from closest margin: 1cm. deep. Tubular Score: 3. Nuclear Grade: 2. Mitotic Score: Modified Scarff Bloom Richardson Grade: 2. Necrosis: Absent. Vascular/Lymphatic Invasion: None identified. Lobular neoplasia: LCIS. Lymph nodes: Sentinel lymph node only. Lymph node status: Negative 0/2. Non-neoplastic areas: columnar cell change, usual ductal hyperplasia, fibroadenomatoid change. DCIS not present. ER/PR/HER2 Results. ER: Positive. PR: Positive. HER2: Negative by FISH. Pathological staging (pTN): pT 2N0. CLINICAL HISTORY: yr old lady underwent screening mammo Left breast density. 3 o'clock position 2.6 x 2.7cm. Core bx. showed invasive ductal carcinoma. ER/PR +, Her2 Negative. Now for WLE needle loc lumpectomy,. SLNB. PRE-OPERATIVE DIAGNOSIS: Left Breast IDC. INTRAOPERATIVE CONSULTATION: TPA/TPB: Negative for tumor cells. Diagnosis called to Dr. at. by Dr. C. Left breast - mass > 1 cm from all margins, nodularity present with minute nodule 0.5cm from. posterior/lateral marain. Per Dr., no gross exam needed on additional lateral margin (Part D). Diagnosis. called to Dr. at. by Dr.. ADDENDUM: NOTE: This addendum is issued to give the results of IHC as well as to correct an error in the diagnosis. for part G. In part G, it says "(SEE NOTE)"; however, there is no note and therefore, the "(SEE NOTE)". is an error. The diagnosis remains unchanged. SUMMARY OF IMMUNOHISTOCHEMISTRY/SPECIAL STAINS. Material: Block C25. Population: Tumor Cells. Stain/Marker: Result: Comment: ECADHERIN Negative Supports lobular differentiation. The interpretation of the above immunohistochemistry stain or stains is guided by published results in. the medical literature, provided package information from the manufacturer and by internal review of. staining performance and assay validation within the Immunohistochemistry Laboratory of the The use. of one or more reagents in the above tests is regulated as an analyte specific reagent (ASR). These. tests were developed and their performance characteristic determined by the Department of Pathology. Laboratory at. They have not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Special stains and/or immunohistochemical stains were performed with appropriately stained positive. and negative controls. Microscopic/Diagnostic Dictation:., Pathologist,. Final Review:., Pathologist,. Final Review: Pathologist. Final:., Pathologist, C. Addendum: Pathologist,. Addendum Final:., Pathologist,.

expanded version (tokens=2770) : 
 Based on the report, the histological classification of the breast pathology is Luminal A subtype of invasive lobular carcinoma with moderate differentiation (SBR grade 2). Other findings include lobular carcinoma in situ, focal atypical ductal hyperplasia, columnar cell change with cytomorphologic atypia (flat epithelial atypia), usual ductal hyperplasia, and fibroadenomatoid change, with negative margins and absent necrosis and lymphovascular invasion. 

The tumor measures 2.6 cm in greatest dimension, with a tubular score of 3, nuclear grade of 2, modified Scarff Bloom Richardson grade of 2, and absent mitotic score. No DCIS is present. The tumor is ER and PR positive, and HER2 negative. 

The patient underwent needle localization wide local excision, sentinel lymph node biopsy (negative for carcinoma), and additional lateral margin excision (negative for carcinoma). Other breast tissues (medial and lateral left breast tissue and right breast tissue) were negative for carcinoma. 

Ancillary testing includes negative ECADHERIN stain, supporting lobular differentiation. The report states that special stains and/or immunohistochemical stains were performed with appropriately stained positive and negative controls. 

In summary, the breast pathology is Luminal A subtype of invasive lobular carcinoma with moderate differentiation, with negative margins and no lymphovascular invasion, and ER and PR positive and HER2 negative status.

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2901) : 
 A 2.6cm Luminal A subtype invasive lobular carcinoma with moderate differentiation was found in the left breast of a patient with ER and PR positive, and HER2 negative status. The tumor was negative for necrosis and lymphovascular invasion, with clear margins. Further excisions of other breast tissue were also negative for carcinoma. Ancillary testing showed negative ECADHERIN stain indicating lobular differentiation.

