prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Basal, SPECIMENS: A. RIGHT BREAST WLE NEEDLE LOCALIZATION. B. ADDITIONAL ANTERIOR INFERIOR MARGIN. C. ADDITIONAL SUPERIOR MARGIN. D. SENTINEL LYMPH NODE #1. E. SENTINEL LYMPH NODE #2. F. RIGHT AXILLARY CONTENTS LEVELS 1 & 2. SPECIMEN(S): A. RIGHT BREAST WLE NEEDLE LOCALIZATION. B. ADDITIONAL ANTERIOR INFERIOR MARGIN. C. ADDITIONAL SUPERIOR MARGIN. D. SENTINEL LYMPH NODE #1. E. SENTINEL LYMPH NODE #2. F. RIGHT AXILLARY CONTENTS LEVELS 1 & 2. GROSS DESCRIPTION: A. RIGHT BREAST WLE NEEDLE LOCALIZATION. Received fresh labeled with the patients identification and "Right Breast WLE needle localization" is an oriented. (Single-Anterior, Double-Lateral, Triple-Superior and Quadruple-Inferior) 59g, 8.5 x 8.5 x 2 1.5cm needle localized. lumpectomy with 2 radiographs. Ink code: Anterior-Yellow, Posterior-Black, Superior-Blue, Inferior-Orange, Medial-. Green, Lateral-Yellow. Specimen serially sectioned from medial to lateral into 7 slices revealing a 2.5 x 1.5 x 1.5cm. tan white firm well circumscribed mass abutting the anterior and posterior margins in slices 3-5. A portion of the. specimen is submitted for tissue procurement. Representative sections are submitted. A1-A3: medial margin slice 1. A4: superior margin slice 2. A5-A6: anterior margin slice 3. A7-A8: deep margin slice 3. A9-A11: anterior margin slice 3. A12-A14: deep margin with mass in A13 slice 3. A15: superior margin slice 4. A16: mass with anterior/deep margin slice 4. A17-A18: mass with anterior margin slice 4. A19-A20: mass with deep margin slice 4. A21: superior margin slice 5. A22-A23: mass with anterior/deep margin slice 5. A24: inferior margin slice 5. A25: area next to mass with anterior/deep margin slice 6. A26: lateral margin slice 7. B. ADDITIONAL ANTERIOR INFERIOR MARGIN. Received fresh labeled with the patient's identification and "Additional Anterior/Inferior margin" is an oriented (Single-. Anterior, Double-Inferior) 19g, 5 x 5 x 2.5cm fragment of fibrofatty tissue. Final Anterior margin is inked Yellow and. the final Inferior margin is inked Orange. Serial sectioning reveals no discrete lesions. Toto B1-B14. C. ADDITIONAL SUPERIOR MARGIN. Received fresh labeled with the patient's identification and "Additional Superior margin" is an oriented (Single-. Anterior, Double-Inferior) 10g, 3 x 3 x 2cm fragment of fibrofatty tissue. Final margin is inked Black. Serial sectioning. reveals no discrete lesions. Toto C1-C7. D. SENTINEL LYMPH NODE #1. Received fresh labeled with the patient's identification and "SLN #1" are two possible lymph nodes 0.8 x 0.8 x 0.5cm. and 0.5 x 0.3 x 0.2cm. A touch prep is taken and the larger lymph node is submitted in FSD. The smaller possible. lymph node is submitted in D2. E. SENTINEL LYMPH NODE #2 (CLUMP OF FREE NODES). Received fresh labeled with the patient's identification and "SLN #2" are 3 tan pink lymph nodes ranging from 1.4 x. 0.9 x 0.8cm to 1.4 x 0.8 x 0.6cm. Toto FSE1, FSE2 and FSE3. F. RIGHT AXILLARY CONTENTS LEVELS 1 & 2. Received in formalin are multiple tan pink soft tissue fragments aggregating to 10 x 10 x 4cm. Dissection reveals. multiple lymph nodes. Entirely submitted: F1: 5 lymph nodes. F2: 5 lymph nodes. F3: 1 lymph node. F4: 1 lymph node. F5: 1 lymph node. F6: 1 lymph node. F7-F8: 1 lymph node. F9-F10: 1 lymph node. F11-F12: 1 lymph node. F13-F20: axillary tissue. SUMMARY OF IMMUNOHISTOCHEMISTRY/SPECIAL STAINS. Material: Block A1. Population: Tissue. Stain/Marker: Result: Comment: CALP. Positive. In DCIS. Material: Block A12. Population: Tissue. Stain/Marker: Result: Comment: CD31. Positive. Material: Block A24. Population: Tissue. Stain/Marker: Result: Comment: CD31. Positive. Material: Block B7. Population: Tissue. Stain/Marker: Result: Comment: ESTROGEN RECEPTOR. Positive Heterogeneous staining consistent with UDH. The interpretation of the above immunohistochemistry stain or stains is guided by published results in the medical. literature, provided package information from the manufacturer and by internal review of staining performance and. assay validation within the Immunohistochemistry Laboratory. The use of one or more reagents in the above tests is. regulated as an analyte specific reagent (ASR). These tests were developed and their performance characteristic. determined by the Department of Pathology Laboratory. They have not been cleared or approved by the U.S. Food. and Drug Administration The FDA has determined that such clearance or approval is not necessary. Special stains and/or immunohistochemical stains were performed with appropriately stained positive and negative. controls. DIAGNOSIS: A. BREAST, RIGHT, NEEDLE LOCALIZATION WIDE LOCAL EXCISION: - INVASIVE DUCTAL CARCINOMA, SBR GRADE 3, WITH MICROPAPILLARY. FEATURES (SEE NOTE). INVASIVE CARCINOMA MEASURES 2.5 CM. - INVASIVE CARCINOMA IS PRESENT AT THE ANTERIOR MARGIN. AND IS 0.3 CM FROM THE POSTERIOR MARGIN. - EXTENSIVE LYMPHVASCULAR INVASION IS PRESENT. DUCTAL CARCINOMA IN SITU (DCIS), SOLID TYPE, NUCLEAR GRADE. 3,. WITH NECROSIS, MINOR COMPONENT. - DCIS IS FOCALLY WITHIN 0.4 CM OF THE MEDIAL MARGIN. - PREVIOUS BIOPSY SITE CHANGES PRESENT. NOTE: The additional anterior inferior margin (specimen B) is free of invasive carcinoma. Surgical correlation is. recommended. CD31 stains show positive staining around tumor foci near. superior and posterior margins consistent with tumor in lymphvascular channels. B. BREAST, RIGHT, ADDITIONAL ANTERIOR INFERIOR MARGIN, EXCISION: - FOCAL ATYPICAL DUCTAL HYPERPLASIA (ADH) AND USUAL DUCTAL. HYPERPLASIA (UDH). C. BREAST, RIGHT, ADDITIONAL SUPERIOR MARGIN, EXCISION: - INVASIVE DUCTAL CARCINOMA, SBR GRADE 3. - TUMOR MEASURES 0.6 CM. - TUMOR IS WITHIN 0.2 CM OF THE NEW MARGIN. - LYMPHVASCULAR INVASION IS PRESENT. - DCIS, SOLID TYPE, NUCLEAR GRADE 3, WITH NECROSIS, MINOR. COMPONENT. D. SENTINEL LYMPH NODE #1, RIGHT AXILLA, BIOPSY: - ONE LYMPH NODE, NO TUMOR SEEN (0/1). E. SENTINEL LYMPH NODE #2, RIGHT AXILLA, BIOPSY: - METASTATIC CARCINOMA TO TWO OF THREE LYMPH NODES, LARGEST. METASTASIS IS 0.7 CM, WITH NO EXTRANODAL EXTENSION (2/3). F. AXILLARY CONTENTS, RIGHT, LEVELS 1 AND 2, DISSECTION: - METASTATIC CARCINOMA TO 3 OF 17 LYMPH NODES, LARGEST. METASTASIS IS 1.5 CM WITH EXTRANODAL EXTENSION (3/17). SYNOPTIC REPORT - BREAST. Specimen Type: Excision. Needle Localization: Yes For mass. Laterality: Right. Invasive Tumor: Present. Multifocality: Yes. WHO CLASSIFICATION. Invasive ductal carcinoma, NOS 8500/3. Tumor size: 2.5cm. Tumor Site: Upper outer quadrant. Margins: Negative. Distance from closest margin: Less than 0.2cm. superior. Tubular Score: 3. Nuclear Grade: 3. Mitotic Score: 3. Modified Scarff Bloom Richardson Grade: 3. Necrosis: Absent. Vascular/Lymphatic Invasion: Present. Extent: extensive. Lobular neoplasia: None. Lymph nodes: Sentinel lymph node and axillary dissection. Lymph node status: Positive 5 / 21 Extranodal extension. Non-neoplastic areas: fibroadenoma. DCIS present. Margins uninvolved by DCIS. DCIS Quantity: Estimate 5%. DCIS Type: Solid. DCIS Location: :Associated with invasive tumor. Nuclear grade: High. Necrosis: Present. ER/PR/HER2 Results. ER: Negative. PR: Negative. HER2: Negative by IHC. Pathological staging (pTN): pT 2 N 2. SYNOPTIC REPORT - BREAST, ER/PR RESULTS. Specimen: Surgical Excision. Block Number: A22 and F12 (lymph node). ER: Negative Allred Score: 0 = Proportion Score 0 + Intensity Score. 0. PR: Negative Allred Score: 0. = Proportion Score 0 + Intensity Score 0. COMMENT: The Allred score for estrogen and progesterone receptors is calculated by adding the sum of the proportion score. (0 = no staining, 1 = <1% of cells staining, 2 = 1 - 10% of cells staining, 3 = 11-30% of cells staining, 4 = 31-60% of. cells staining, 5 = >60% of cells staining) to the intensity score (1 = weak intensity of staining, 2 = intermediate. intensity of staining, 3 = strong intensity of staining), with a scoring range from 0 to 8. ER/PR positive is defined as an Allred score of >2 and ER/PR negative is defined as an Allred score of less than. or equal to 2. METHODOLOGY: Tissue was fixed in 10% neutral buffered formalin for no less than 8 and no longer than 24 hours. Immunohistochemistrv was performed using the mouse anti-human ER (ER 1D5, 1:100) and PR (PGR 136, 1:100). provided by Dako. following the manufacturer S instructions. This assay was not modified. Interpretation of the ER/PR immunohistochemical stain is guided by published results in the medical literature,. information provided by the reagent manufacturer and by internal review of staining performance. SYNOPTIC REPORT - BREAST HER-2 RESULTS. Specimen: Surgical Excision. Block Number: F12 (lymph node). Interpretation: NEGATIVE. Intensity: 1+. % Tumor Staining: 5%. Fish Ordered: No. METHODOLOGY: Tissue was fixed in 10% neutral buffered formalin for no less than 8 and no longer than 24 hours. Her2 analysis. was performed using the FDA approved Dako HercepTes (TM) test kit. using rabbit anti-. human HER2. This assay was not modified. External kit-slides provided by the manufacturer (cell lines with. high,. low and negative HER2 protein expression) and in-house known HER2 amplified control tissue were evaluated along. with the test tissue. Adequate, well preserved, clear-cut invasive carcinoma was identified for HER2 evaluation. Interpretation of the HER2 immunohistochemical stain is guided by published results in the medical literature,. information provided by the reagent manufacturer and by internal review of staining performance. This assay has been validated according to the 2007 joint recommendations and guidelines from ASCO and CAP. and from the NCCN HER2 testing in Breast Cancer Task Force. The Pathology Department takes full responsibility. for this test's performance. CLINICAL HISTORY: year old female with Abnormal MMG- Bx Right Breast at 9-10 o'clock IDC ER-. MRI showed additional. abnormality 2.6cm posterior to this. PRE-OPERATIVE DIAGNOSIS: Right Breast Cancer. INTRAOPERATIVE CONSULTATION: FSD-TPD: One lymph node negative for tumor. FSE1-FSE2-FSE3: Positive for metastatic Adenocarcinoma. Diagnoses called to Dr. at . (D) and. I (E) by Dr. Microscopic/Diagnostic Dictation: Pathologist,. Final Review: Pathologist,. Final Review: Pathologist,. Final: Pathologist,.

expanded version (tokens=3352) : 
 Histological Classification:
- Invasive Ductal Carcinoma, SBR grade 3, with micropapillary features
- Ductal Carcinoma In Situ (DCIS), solid type, nuclear grade 3, with necrosis
- Focal Atypical Ductal Hyperplasia (ADH) and Usual Ductal Hyperplasia (UDH)

Necrosis: Present in DCIS, minor component

Tumor Infiltrating Lymphocytes: Not mentioned in the report

Histological Grade: SBR grade 3

Nuclear Grade: 3

Lymphovascular Invasion: Extensive lymphovascular invasion is present

Calcifications: Not mentioned in the report

Receptor Status:
- Estrogen Receptor (ER): Negative
- Progesterone Receptor (PR): Negative
- HER2: Negative

IHC (Immunohistochemistry):
- CALP: Positive in DCIS
- CD31: Positive in several sections
- ER: Negative
- PR: Negative
- HER2: Negative (1+ staining, 5% tumor staining)

Ancillary Testing:
- Fish Ordered: No

Additional Information:
- Multiple specimens were received for analysis, including WLE needle localization, additional anterior inferior margin, additional superior margin, lymph node biopsies, and axillary content dissection.
- The invasive carcinoma measures 2.5 cm and is present at the anterior margin

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3503) : 
 Invasive ductal carcinoma, SBR grade 3 with micropapillary features, measuring 2.5 cm, is present at the anterior margin. Extensive lymphovascular invasion and necrotic DCIS are observed. Focal atypical ductal hyperplasia is seen in the additional anterior inferior margin. ER, PR, and HER2 are negative by IHC. Metastatic carcinoma is identified in two sentinel lymph nodes and three out of 17 axillary lymph nodes with extranodal extension.

