prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - SPECIMENS: A. EXCISION RIGHT BREAST NEEDLE LOCALIZATION. B. LEFT BREAST AND AXILLARY CONTENTS. C. ADDITIONAL LEFT AXILLARY TISSUE. SPECIMEN(S): A. EXCISION RIGHT BREAST NEEDLE LOCALIZATION. B. LEFT BREAST AND AXILLARY CONTENTS. C. ADDITIONAL LEFT AXILLARY TISSUE. DIAGNOSIS: A. BREAST, RIGHT, NEEDLE LOCALIZATION EXCISIONAL BIOPSY: DUCTAL CARCINOMA IN SITU (DCIS), CRIBRIFORM TYPE, NUCLEAR. GRADE 2, WITH NECROSIS AND MICROCALCIFICATIONS. - DCIS IS PRESENT AT THE MEDIAL MARGIN, IS WITHIN 0.1 CM. OF THE POSTERIOR AND SUPERIOR MARGINS, AND IS WITHIN. 0.2 CM OF THE ANTERIOR MARGIN. - ATYPICAL INTRADUCTAL PAPILLOMAS, 0.1 CM FROM THE MEDIAL. MARGIN. - COMPLEX SCLEROSING LESION WITH EXTENSIVE LOBULAR CARCINOMA. IN SITU (LCIS), INTRADUCTAL PAPILLOMAS, SCLEROSING ADENOSIS,. APOCRINE METAPLASIA, AND MICROCALCIFICATIONS. NOTE: DCIS is present in 3 of 10 slides. On a single slide, DCIS measures 0.8 cm. Immunostains were. performed with appropriate positive and negative controls. SMMHC, p63, and calponin are positive,. showing no evidence of invasive carcinoma. B. BREAST, LEFT, AND AXILLARY CONTENTS, MODIFIED RADICAL MASTECTOMY: - INVASIVE LOBULAR CARCINOMA, NOTTINGHAM GRADE 3. - 3.3 CM IN SIZE. - EXTENSIVELY INVOLVES THE NIPPLE DERMIS. - LOBULAR CARCINOMA IN SITU (LCIS), PLEOMORPHIC TYPE, WITH. FOCAL NECROSIS. - MARGINS, NEGATIVE FOR CARCINOMA. - ATYPICAL DUCTAL HYPERPLASIA. - METASTATIC CARCINOMA IN 20 OF 24 LYMPH NODES WITH. EXTRANODAL EXTENSION, LARGEST METASTASIS IS 2.4 CM (20/24). C. ADDITIONAL AXILLARY TISSUE, LEFT, EXCISION: - METASTATIC CARCINOMA IN ONE LYMPH NODE AND TUMOR. IN FIBROADIPOSE TISSUE (1/1). NOTE: There is a 0.4 cm focus of invasive carcinoma in the fibroadipose tissue with no definite lymph. node adjacent to the focus and no breast parenchyma present. This focus is best interpreted as. extranodal extension. SYNOPTIC REPORT - BREAST. Specimens Involved. Specimens: A: EXCISION RIGHT BREAST NEEDLE LOCALIZATION. Specimen Type: Excision. Needle Localization: Yes - For mass. Laterality: Right. Invasive Tumor: Absent. Multifocality: N/A. WHO CLASSIFICATION. Intraductal proliferative lesions. Ductal carcinoma in situ 8500/2. DCIS present. Margins involved by DCIS: : medial margin. DCIS Type: Cribriform. DCIS Size (pure DCIS only): 0.8cm. Nuclear grade: Intermediate. Necrosis: Present. Location of CA++: DCIS. Benign epithelium. ER/PR/HER2 Results. ER: Positive. PR: Positive. Performed on Case: Pathological staging (pTN): pT is N X. Pathological staging is based on the AJCC Cancer Staging Manual, 7th Edition. SYNOPTIC REPORT - BREAST, ER/PR RESULTS. Specimens Involved. Specimens: A: EXCISION RIGHT BREAST NEEDLE LOCALIZATION. Specimen: Surgical Excision. Block Number: A2. ER: Positive. Allred Score: 8 = Proportion Score 5 + Intensity Score 3. PR: Positive. Allred Score: 8 = Proportion Score 5 + Intensity Score 3. COMMENT: The Allred score for estrogen and progesterone receptors is calculated by adding the sum of the. proportion score (0 = no staining, 1 = <1% of cells staining, 2 = 1 - 10% of cells staining, 3 = 11-30% of. cells staining, 4 = 31-60% of cells staining, 5 = >60% of cells staining) to the intensity score (1 = weak. intensity of staining, 2 = intermediate intensity of staining, 3 = strong intensity of staining), with a scoring. range from 0 to 8. ER/PR positive is defined as an Allred score of >2 and ER/PR negative is defined as an Allred score. of less than or equal to 2. METHODOLOGY: Tissue was fixed in 10% neutral buffered formalin for no less than 8 and no longer than 24 hours. Immunohistochemistry was performed usina the mouse anti-human ER (ER 1D5, 1:100) and PR (PGR. assay was not modified. Interpretation of the ER/PR immunohistochemical stain is guided by published. 136, 1:100) provided by. ) following the manufacturer S instructions. This. results in the medical literature, information provided by the reagent manufacturer and by internal. review of staining performance. SYNOPTIC REPORT - BREAST. Specimens Involved. Specimens: B: LEFT BREAST AND AXILLARY CONTENTS. C: ADDITIONAL LEFT AXILLARY TISSUE. Specimen Type: Mastectomy. Needle Localization: Laterality: Left. Invasive Tumor: Present. Multifocality: No. WHO CLASSIFICATION. Invasive lobular carcinoma 8520/3. Tumor size: 3.3cm. Tumor Site: Central. Margins: Negative. Distance from closest margin: 0.9cm. deep. Tubular Score: 3. Nuclear Grade: 3. Mitotic Score: 2. Modified Scarff Bloom Richardson Grade: 3. Necrosis: Absent. Lobular neoplasia: LCIS. Lymph nodes: Axillary dissection. Lymph node status: Positive 21/25 Extranodal extension. DCIS not present. ER/PR/HER2 Results. ER: Positive. PR: Positive. HER2: Negative by FISH. Performed on Case: Pathological staging (pTN): pT 2 N 3. Pathological staging is based on the AJCC Cancer Staging Manual, 7th Edition. GROSS DESCRIPTION: A. EXCISION RIGHT BREAST NEEDLE LOCALIZATION. Received fresh labeled with the patient's identification and "right breast needle localization" is an. oriented (short stitch-superior, long stitch-lateral, double stitch-deep), 35 g, 5.5 x 5.5 x 2.5 cm needle. localized lumpectomy with radiographs. Ink code: Anterior-yellow, posterior-black, medial-green, lateral-. red, superior-blue, inferior-orange. The specimen is serially sectioned from medial to lateral into 7 slices. revealing a 1.7 x 0.7 X 0.4 cm gritty, lobulated white tumor that is closest to the anterior margin at 0.1. cm. A clip is identified in slice 2. No additional lesions are noted. Representatively submitted: A1-medial margin. A2-slice 2, superior margin. A3-4-slice 2, anterior/posterior margins to tumor. A5-A8-slice 3, full cross-section/tumor. A9-slice 4, additional deep margin to firmer fibrous tissue. A10-lateral margin. B. LEFT BREAST AND AXILLARY CONTENTS. Received fresh labeled with the patient's identification and "left breast and axillary contents" is an. oriented 1150 g, 26 x 21 X 4 cm mastectomy with a 15 x 7 cm skin ellipse and 1.5 cm in diameter. inverted nipple. There is also 15 x 11 cm attached axillary tissue. Ink code: Posterior-black, anterior. superior-blue, anterior inferior-orange. The specimen is serially sectioned into 12 slices from medial to. lateral with nipple in slices 5/6 revealing a retroareolar, 3.3 x 3 x 2.7 cm infiltrative, gritty indurated,. lobulated tan to white tumor in slices 5 and 6, closest to the anterior margin (areolar skin) at 0.5 cm. No. additional lesions are identified. There are 24 possible lymph nodes identified, ranging from 0.2 cm to. 2.4 cm in greatest dimension. Representatively submitted: B1-deep margin closest to tumor, slice 5. B2-B3-entire nipple, slices5-6. B4-tumor to closest anterior (skin) margin, slice 6. B5-B7-additional tumor, slice 6. B8-UOQ, slice 9. B9-LOQ, slice 8. B10-UIQ, slice 4. B11-LIQ, slice 4. B12-superior skin margin, shave. B13-6 lymph nodes. B14-one trisected lymph node. B15-6 lymph nodes. B16-5 lymph nodes. B17-one bisected lymph node. B18-2 lymph nodes. B19-2 lymph nodes. B20-one lymph node. LH. C. ADDITIONAL LEFT AXILLARY TISSUE. Received in formalin labeled with patient's identification and "additional left axillary tissue" is adipose. tissue measuring 3 x 2.5 X 1 cm in aggregate. Representative sections submitted in C1. CLINICAL HISTORY: ; year-old female with multicentric left breast cancer; FNA-positive lymph nodes and right mass biopsy. shows atypia, left mass retroareolar, right atypical ductal hyperplasia at 12:00. PRE-OPERATIVE DIAGNOSIS: Invasive pleomorphic lobular carcinoma retroareolar, left breast. Microscopic/Diagnostic Dictation:,. Microscopic/Diagnostio Dictation:,. Final Review:., Pathologist,. Final:., Pathologisi.

expanded version (tokens=2677) : 
 The breast pathology report includes:

1. Excision right breast needle localization:

- Histological classification: Ductal Carcinoma In Situ (DCIS), Cribiform type, nuclear grade 2, with necrosis and microcalcifications.
- Subtype: Cribriform
- Description of necrosis: Present
- Mention of tumor infiltrating lymphocytes: not mentioned
- Histological grade: Nuclear grade 2
- Lymphovascular invasion: not mentioned
- Calcification: Present
- Receptor status: ER/PR positive by immunostaining
- IHC: SMMHC, p63, and calponin are positive, showing no evidence of invasive carcinoma

2. Left breast and axillary contents:

- Histological classification: Invasive lobular carcinoma, Nottingham grade 3 
- Subtype: Pleomorphic 
- Description of necrosis: Absent
- Mention of tumor infiltrating lymphocytes: not mentioned
- Histological grade: Modified Scarff Bloom Richardson Grade 3
- Lymphovascular invasion: not mentioned
- Calcification: not mentioned
- Receptor status: ER/PR positive by immunostaining; HER2 negative by FISH
- IHC: ER and PR stains were performed, and the Allred scores for both were 8

3. Additional left axillary tissue:

- Histological classification: Metastatic carcinoma in one lymph node and tumor in fibroadipose tissue

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2829) : 
 The biopsy report shows ductal carcinoma in situ (DCIS), cribiform type, with necrosis and microcalcifications in the excised right breast needle localization. Invasive pleomorphic lobular carcinoma with lymph node metastasis was found in a modified radical mastectomy of the left breast and axillary contents. ER/PR-positive by immunostaining; HER2-negative by FISH. There was metastatic carcinoma in one lymph node and tumor in fibroadipose tissue upon examination of additional left axillary tissue.

