prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - F. Pathologic Interpretation: A. RIGHT BREAST TOTAL MASTECTOMY: INVASIVE LOBULAR CARCINOMA, moderately differentiated, Nottingham grade 2 (3+2+2=7), 5.5 cm in. greatest dimension. Margins are negative for carcinoma, closest margin is posterior (3.5 cm). Negative for lymphovascular invasion. Lobular carcinoma in situ is present. Skin and nipple with no significant pathologic changes. See Surgical Pathology Cancer Case Summary. B. RIGHT BREAST AXILLA SENTINEL NODE #1: Negative for carcinoma in one lymph node examined (0/1). Keratin immunostains will follow. Surgical Pathology Cancer Case Summary: INVASIVE CARCINOMA OF THE BREAST: Specimen: Total breast (including nipple and skin). Procedure: Total mastectomy (including nipple and skin). Lymph Node Sampling: Sentinel lymph node(s). Specimen Integrity: Single intact specimen (margins can be evaluated). Specimen Size: Greatest dimension: 25 cm. Additional dimensions: 15.5 x 5.6 cm. Specimen Laterality: Right. Tumor Site: Invasive Carcinoma: Central. Tumor Size: Size of Largest Invasive Carcinoma: Greatest dimension of largest focus of invasion: 5.5 cm. Additional dimensions: 3.5 x 3.0 cm. Tumor Focality: Single focus of invasive carcinoma. Macroscopic and Microscopic Extent of Tumor: Skin: Invasive carcinoma does not invade into the dermis or epidermis. Nipple: DCIS does not involve the nipple epidermis. Skeletal Muscle: No skeletal muscle present. Ductal Carcinoma In Situ (DCIS): No DCIS is present. Histologic Type of Invasive Carcinoma: Invasive lobular carcinoma. Histologic Grade: Nottingham Histologic Score: Glandular (Acinar)/Tubular Differentiation: Score 3. Nuclear Pleomorphism: Score 2. Mitotic Count: Score 2. Overall Grade: Grade 2. Margins: Uninvolved by invasive carcinoma. Distance from closest margin: 35 mm, all other margins >5 cm. Treatment Effect: Response to Presurgical (Neoadjuvant) Therapy: In the breast: No known presurgical therapy. Lymph-Vascular Invasion: Not identified. Lymph Nodes: Number of sentinel lymph nodes examined: 1. Total number of lymph nodes examined (sentinel and nonsentinel): 1. Number of lymph nodes with macrometastases: 0. Number of lymph nodes with micrometastases: 0. Number of lymph nodes with isolated tumor cells: 0. Method of Evaluation of Sentinel Lymph Nodes: H&E, multiple levels. Pathologic Staging: Primary Tumor: pT3. Regional Lymph Nodes: pNO. Distant Metastasis: Not applicable. Ancillary Studies: Estrogen Receptor: Performed on another specimen (xxxx). Results: POSITIVE (>50%). Progesterone Receptor: Performed on another specimen (xxxx). Results: POSITIVE (>50%). HER2/neu: Immunoperoxidase Studies: Performed on another specimen. Results: Equivocal (Score 2+). Chromogenic In Situ Hybridization (CISH) for HER2/neu: Performed on another specimen (xxxx). Results: Not amplified (HER2 gene copy <4.0 or ratio <1.8). Comment(s): AJCC Classification (7th edition): pT3, NO, Mn/a. NOTE: Some immunohistochemical antibodies are analyte specific reagents (ASRs) validated by our laboratory. These ASRs are clinically useful indicators that do not require FDA approval. These clones are used: IDS=ER, PgR 636=PR, A485=HER2, H-11=EGFR. All immunohistochemical stains are used with formalin or molecular fixed, paraffin embedded tissue. Detection is by. Envision Method. The results are read by a pathologist as positive or negative. As the attending pathologist, I attest that I: (i) Examined the. relevant preparation(s) for the specimen(s); and (ii) Rendered the. diagnosis(es). X. Clinical History: cT3 NX MX infiltrating lobular carcinoma, low-grade, right breast. Please evaluate sentinel nodes on permanent with IHC. Axillary node dissection will be done today only if no sentinel. lymph nodes can be identified and removed. Operation Performed. Right total mastectomy, Sentinel node biopsy, Possible axillary node dissection. Pre Operative Diagnosis: Infiltrating lobular carcinoma >5 cm. Specimen(s) Received/Processing Information: Fee. Codes: A: RIGHT BREAST MASS (2 SUTURES MEDIAL, 1 SUTURE SUPERIOR) H&E, Initial x. A: IHC, IHC, IHC,. 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial. x 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial x 1, H&E, Initial x 1, E-CADHERIN x 1, Beta. IHC, IHC, IHC,. Catenin x 1, Vimentin x 1, Cytokerat. IHC. B: IHC, IHC. B: RIGHT BREAST SENTINEL NODE AXILLA # 1, COUNT 5356 H&E, Initial x 1, H&E,. Initial X 1, Cytokeratin Cocktail (KER) x 1, Cytokeratin Cocktail (KER) x 1. Gross Description: A. Received in formalin labeled "Right breast mass" is a 1050-gram mastectomy specimen (25.0 x 15.5 x 5.6. cm) with a tan-. white skin ellipse (25.4 x 10.0 cm) and nipple (1.8 x 1.6 x 0.4 cm) and two sutures indicating medial and one. suture. indicating superior. There are no visible lesions or scars present. The specimen was previously serially. sectioned with. black ink added on the posterior aspect. There is a hard tan-white, ill-defined centrally located (5.5 x 3.5 x. 3.0 cm),. located 3.5 cm from the deep margin and more than 5.0 cm from the remaining margins. The remaining. breast stroma is. markedly fibrotic with cystic areas filled with a clear fluid measuring up to 0.6 cm in greatest diameter. The. stroma to. adipose ratio is 50:50. Representative sections are submitted in eleven cassettes as follows: Cassette #1. Deep margin. Cassette #2. Upper outer. Cassette #3. Upper inner. Cassette #4. Lower outer. Cassette #5. Lower inner. Cassettes #6-10. Composite section of mass. Cassette #11. Nipple. B. Received in formalin labeled "Right breast sentinel node, axilla #1 count 5356" is a segment of adipose. tissue (4.0 x 3.7 x. 1.3 cm). Sectioning reveals a possible lymph node measuring 1.6 x 1.0 x 0.5 cm. The lymph node is. trisected and. submitted in toto in two cassettes.

expanded version (tokens=2028) : 
 The breast pathology report indicates that there is invasive lobular carcinoma, which is moderately differentiated and has a Nottingham grade 2 (3+2+2=7). It measures 5.5 cm in the greatest dimension. The margins are negative for carcinoma with the closest margin being posterior (3.5 cm). There is no lymphovascular invasion. Lobular carcinoma in situ is also present.

The histological type of the invasive carcinoma is lobular carcinoma, while the histologic grade is Nottingham Histologic Score- glandular (Acinar)/Tubular Differentiation: Score 3, Nuclear Pleomorphism: Score 2, Mitotic Count: Score 2 with an overall grade of Grade 2. 

The report indicates that receptor status was tested on another specimen, with both estrogen receptors and progesterone receptors testing positive (>50%). The HER2/neu testing was equivocal, with Chromogenic In Situ Hybridization (CISH) showing that it is not amplified (HER2 gene copy <4.0 or ratio <1.8). 

There is no mention of tumor infiltrating lymphocytes, calcification, or any other ancillary testing results other than the IHC testing mentioned above. The surgical pathology cancer case summary notes that the AJCC Classification (7th edition) is pT3, NO, Mn/a. 

The report confirms that the lymph nodes are negative for carcinoma in one lymph node examined (0/1). The sentinel node was

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2174) : 
 The patient had a right breast total mastectomy with 5.5 cm moderately differentiated invasive lobular carcinoma and negative margins for carcinoma. Receptor status testing found estrogen and progesterone receptors positive and HER2/neu equivocal, but not amplified. There was no lymphovascular invasion or tumor-infiltrating lymphocytes identified. Lobular carcinoma in situ was present, and the AJCC classification is pT3, NO, Mn/a. The sentinel node tested negative for carcinoma.

