prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Her2, ¿PORT - REVIEW ADDENDUM SECTION. DIAGNOSIS. (A) RIGHT AXILLARY SENTINEL LYMPH NODE #1, BIOPSY: SINGLE KERATIN-POSITIVE CELL SUSPICIOUS FOR ISOLATED TUMOR CELL IN ONE LYMPH NODE. (SEE. COMMENT). (B) RIGHT AXILLARY SENTINEL LYMPH NODE #2, BIOPSY: One lymph node, no tumor present (0/1). (C) RIGHT BREAST, TOTAL MASTECTOMY: INVASIVE DUCTAL CARCINOMA WITH ASSOCIATED MILD LYMPHOCYTIC INFILTRATE, HIGH NUCLEAR GRADE,. NOTTINGHAM HISTOLOGIC GRADE 3. (SEE COMMENT). INVASIVE TUMOR IS LOCATED IN THE UPPER OUTER QUADRANT AND MEASURES 1.5 CM IN GREATEST. DIMENSION. FEW ADJACENT DUCTS WITH DUCTAL CARCINOMA IN SITU (DCIS), HIGH NUCLEAR GRADE, SOLID AND. CRIBRIFORM TYPES WITH FOCAL COMEDONECROSIS, ASSOCIATED MICROCALCIFICATIONS, AND. CANCERIZATION OF LOBULES. Columnar cell hyperplasia with associated calcifications also adjacent to tumor. SINGE FOCUS OF INTRALYMPHATIC TUMOR. (SEE COMMENT). Tumor does not approach surgical margins. Remaining breast tissue with mild fibrocystic change. Entire report and diagnosis completed by. COMMENT. No tumor cells are identified on the H&E stains of the sentinel lymph nodes. Immunostains for keratin were performed on each. of the sentinel nodes (A1-A2, B1-B2), and a single keratin-positive cell suspicious for an isolated tumor cell is present on one of. the keratin stains from sentinel node #1 (A2). A single cluster of tumor cells is noted within a dilated lymphatic channel next to the tumor. Because the channel is quite. dilated and only a single focus is identified, it is unclear whether this represents true peritumoral lymphovascular invasion or. displacement artifact. Tumor marker studies including FISH for HER2 gene copy level were reported previously (see. Because only 5%. staining for estrogen receptor was reported, hormone receptor staining will be repeated on this specimen and reported in an. addendum. GROSS DESCRIPTION. (A) RIGHT AXILLARY SENTINEL LYMPH NODE #1, IN VIVO 195, EX VIVO 181 - A 1.5 x 1.0 x 0.6 cm possible lymph node,. serially sectioned and submitted entirely for frozen section in A1, A2. FS/DX: NO TUMOR IDENTIFIED. (B) RIGHT AXILLARY SENTINEL LYMPH NODE #2, IN VIVO 40, EX VIVO 28 - A 1.6 x 1.5 x 0.9 cm possible lymph node,. serially sectioned and submitted entirely in B1, B2. FS/DX: NO TUMOR IDENTIFIED. RIGHT TOTAL MASTECTOMY - A right total mastectomy specimen (22.0 x 16.0 x 4.5 cm) with attached skin ellipse (10.0 x. 5.2 x 0.5 cm). The skin ellipse contains an unremarkable nipple (1.0 cm). The specimen is sectioned from lateral to medial into. ten slices with the nipple in slices 7 and 8. An. irregular. (1.5 x 1.5 x 1.2 cm) solid white, gritty mass is identified in slice 6, located 2.5 cm from the deep margin, 5.2. cm from the inferior margin, 5.5 cm from the superior margin, 5.5 cm from the skin, 6.5 cm from the lateral margin, and 6.0 cm. com the medial margin. The rest of the breast parenchyma is grossly unremarkable. INK CODE: Blue - superior; orange - inferior; black - deep. SECTION CODE: C1, superior margin; C2, inferior margin; C3, deep margin; C4, medial margin; C5, lateral margin; C6,. skin. closest. to tumor; C7, base of nipple; C8, cross sections of tip of nipple; C9 and C10, tumor; C11, breast tissue deep to tumor;. C12, breast tissue medial to tumor; C13, breast tissue lateral to tumor; C14, breast tissue inferior to tumor; C15, breast tissue. superior to tumor; C16, C17, representative sections from upper outer quadrant; C18, C19, representative sections of lower outer. quadrant; C20, C21, representative sections of upper inner quadrant; C22, C23, representative sections of lower inner quadrant;. C24, breast tissue anterior to tumor. CLINICAL HISTORY. Carcinoma of right breast. SNOMED CODES. T-04050, M-85002, M-85003, T-C4714, M-85017. "Some tests reported here may have been developed and performance characteristics determined by. These tests have not been specifically cleared or approved by the U.S. Food and Drug Administration.". Released by: Start of ADDENDUM. ADDENDUM. Addendum completed hv. This report is issued to give immunohistochemistry results. Immunohistochemical staining is performed on a representative formalin-fixed, paraffin-embedded section of INVASIVE DUCTAL. CARCINOMA, right breast, block C9. MARKER. % POSITIVE. Estrogen Receptor. Low Positive (1-9%). 5 %. Progesterone Receptor. Negative. 0 %. Ki-67. High (>35%). approx. 50 %. COMMENT. See. ! for HER2 immunostaining and FISH results. FOOTNOTE. Estrogen receptor was assessed by immunohistochemistry using antibody 6F11. Progesterone receptor was assessed by immunohistochemistry using antibody PgR1294. Ki-67 was assessed by immunohistochemistry using antibody MIB1. Released by:

expanded version (tokens=1741) : 
 The histological classification of the breast pathology report is invasive ductal carcinoma with associated lymphocytic infiltrate, high nuclear grade, and Nottingham histologic grade 3. The subtype of cancer is HER2 positive. The report mentions a few adjacent ducts with DCIS, high nuclear grade, solid and cribiform types with focal comedonecrosis, associated microcalcifications, and cancerization of lobules. Columnar cell hyperplasia with associated calcifications is also adjacent to the tumor. There is a single focus of intralymphatic tumor. Necrosis is seen in the form of focal comedonecrosis. Tumor infiltrating lymphocytes are mentioned as mild lymphocytic infiltrate. The histological grade is Nottingham grade 3, which is the highest grade indicating poorly differentiated cancer cells. Nuclear grade is high, indicating an aggressive type of cancer. Lymphovascular invasion is mentioned as a single cluster of tumor cells within a dilated lymphatic channel near the tumor, but it is unclear if this represents true peritumoral lymphovascular invasion or displacement artifact. Calcification is associated with the DCIS component. Receptor status shows low positive estrogen receptor (5%) and negative progesterone receptor. Ki-67 staining is high, indicating a highly proliferative tumor. Immunostaining for HER2 and FISH results are not mentioned in the main report but are provided in the addendum, where it is mentioned that the subtype is HER2 positive.

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1883) : 
 Breast pathology report shows HER2 positive invasive ductal carcinoma with high nuclear grade and Nottingham histologic grade 3. Tumor infiltrating lymphocytes are mild, and calcification is associated with DCIS component. Lymphovascular invasion is uncertain. Receptor status shows low estrogen receptor (5%) and negative progesterone receptor. Ki-67 staining is high (>35%). Immunostaining for HER2 and FISH results confirm subtype as Her2 positive.

