prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Basal, RUN DATE. RUN TIME. RUN USER. ACCT # : AGE/SX: ROOM : REG DR. BED: SPEC #. RECD: COLL: TIME IN FORMALIN: 6:29. nrs. COLD ISCHEMA TIME: 0:00. mins,. CLINICAL INFORMATION: Pre-Op Diagnosis: Right breast mass. Remarks: Specimen (s) : A. Right breast mass. B. Right breast sentinel node. C. Posterior medial margin. D. Medial margin. MICROSCOPIC DIAGNOSIS. A. BREAST, RIGHT (REGION NOT OTHERWISE STATED). LUMPECTOMY: INVASIVE GRADE 3 DUCTAL CARCINOMA MEASURING 3.5 CM IN GREATEST DIMENSION. ASSOCIATED HIGH-GRADE DUCTAL CARCINOMA IN SITU (DCIS) WITH CANCERIZATION OF THE. LOBULES AND COMEDO NECROSIS; NOT EXTENSIVE. NO ANGIOLYMPHATIC INVASION IDENTIFIED. TUMOR FOCALLY INVOLVES INKED DEEP MARGIN ADJACENT TO SKELETAL MUSCLE TISSUE (NOT. IN SKELETAL MUSCLE). HEALING WOUND REACTION CONSISTENT WITH PREVIOUS CORE NEEDLE BIOPSY. B. SENTINEL LYMPH NODE, RIGHT AXILLA, EXCISION: ONE (1) LYMPH NODE NEGATIVE FOR METASTATIC CARCINOMA BY ROUTINE LIGHT MICROSCOPY. AND CYTOKERATIN (PANK+) IMMUNOSTAIN. C. ADDITIONAL RIGHT BREAST LUMPECTOMY POSTERIOR MEDIAL MARGIN: ADIPOSE AND SKELETAL MUSCLE TISSUE, NEGATIVE FOR CARCINOMA. D. RIGHT BREAST LUMPECTOMY MEDIAL MARGIN: FIBROADIPOSE BREAST TISSUE AND SKELETAL MUSCLE TISSUE. NEGATIVE FOR CARCINOMA. COMMENT(S. The large mass is a poorly differentiated ductal carcinoma Microscopically the tumor. does focally extend to the inked deep margin which is adjacent to the skeletal muscle. tissue on the medial half The additional margin tissue submitted for evaluation is. negative for carcinoma and. assuming that this tissue was obtained from the region. of the positive margin on the original specimen, would provide an additional 0.8 cm to 1 cm. margin. Protocol for the Examination of Specimens From Patients With Invasive Carcinoma of the. RUN DATE : RUN TIME: RUN USER: SPEC #: COMMENT ( S). Breast. Based on AJCC/UICC TNM. 7th edition. Procedure: Excision without wire-guided localization. Lymph Node Sampling: Sentinel lymph node. Specimen Laterality: Right. Histologic Type: Invasive ductal carcinoma (NOS). Tumor Size. Greatest dimension : 3.5 cm. Histologic Grade (Nottingham) : Glandular Differentiation Score 2. Nuclear Pleomorphism: Score 3. Mitotic Rate: Score 3. Overall Grade: Grade 3. Tumor Focality: Single focus of invasive carcinoma. Ductal Carcinoma In Situ: DCIS i's present. Margins: Margins uninvolved by invasive carcinoma (see. comment above). DCIS: Margins uninvolved by DCIS. Lymph Nodes: Number of sentinel lymph nodes examined : 1. Total number of lymph nodes examined (sentinel and. nonsentinel) : 1. Number of lymph nodes without tumor cells. identified : 1. Pathologic Staging: Primary Tumor: pT2. Regional Lymph Nodes: Modifier: sn. Category: pNO (i-). Distant Metastasis: Not applicable. Ancillary Studies: ER: Negative. PR: Positive (3% tumor cells with weak staining. intensity). HER2 Immunoperoxidase Studies: Equivocal (Score 2+). In Situ Hybridization: Amplified. Average Number HER2 Gene Copies Per Cell: 5.4. Average Number of Chromosome 17 Per Cell: 2.0. GROSS DESCRIPTION: A. Received fresh for gross evaluation of margins and selection of tissue for tissue bank. is a lumpectomy specimen which weighs 51 grams and measures 6.5 x 6.5 x 3 cm. There is a. 3.5 x 1 cm ellipse of dark brown skin. There is a 2.5 x 2.5 cm portion of skeletal muscle. on the undersurface On palpation, a mass is appreciated Two sutures orient the specimen. as follows: lateral long stitch and superior short stitch Dr. also placed a smaller. stitch which represents closure of a flap of tissue representing additional tissue at. the superior aspect The specimen is inked as follows: superio-anterior blue, inferio-. anterior black, lateral yellow. medial red. and deep green The specimen is placed. into. Bouin's solution. The specimen is serially sectioned revealing a retracted yellowish white. tumor which measures 3.5 x 2.2 x 1.7 cm. Core needle biopsy tracts are within the mid. portion of the tumor. The closest margin is the inked deep margin where the tumor abuts. RUN DATE: RUN TIME: RUN USER: SPEC #. GROSS DESCRIPTION: (Continued). this margin in the medial half A portion of the tumor is provided to the tissue banking. coordinator. The results of the margin status were given to Dr. in the operating. room at. Cassette Summary: 1. perpendicular sections of medial margin. 2. perpendicular sections of lateral margin. 3,4. closest deep margin. 5.6. a full cross-section of tumor, superficial and deep. 7.8. full cross-section of tumor. 9. section of tumor in vicinity of muscle. 10. additional section. B. Received fresh for gross intraoperative evaluation labeled with the patient's name and. "right breast sentinel node" is a 4 x 2 x 1 cm ovoid portion of fatty tissue. Sectioning. reveals a single 3 x 1.5 x 1 cm partially blue dye-stained tan lymph node. The. lymph node is serially sectioned perpendicular to the long axis. No gross obvious. carcinoma. The results are relayed to Dr. in the operating room. The specimen is. totally submitted in blocks B1 through B4 for sentinel lymph node protocol. C. Received fresh labeled with the patient's name and "right breast lumpectomy posterior. medial margin" is an additional <2 gram portion of fibroadipose tissue measuring 3 x 1.5 x. 0.8 cm. Muscle is present on one end. À long stitch marks the medial side away from the. tumor. Short stitch is superior. Blue ink is applied to the new posterior deep margin. The. specimen is serially sectioned with the superior half submitted in block C1 and the. inferior half in block C2. D. Received fresh labeled with the patient's name and "right breast lumpectomy medial. margin" is an additional <2 gram. 3 x 1.5 x 1 cm portion of fibroadipose tissue. A long. stitch marks the medial side away from the tumor and the short stitch marks superior. Black ink is applied to the new medial margin. The specimen is serially sectioned and. submitted in blocks D1 and D2 with the superior half in block D1 and the inferior half in. block D2. INTRAOPERATIVE CONSULTATION: A. RIGHT BREAST: CLOSEST MARGIN DEEP, MEDIAL ASPECT. WITH TISSUE PROVIDED TO TISSUE BANK. COORDINATOR. RESULTS DISCUSSED WITH DR. IN THE OPERATING ROOM. B. SENTINEL LYMPH NODE: ONE LYMPH NODE WITH NO GROSS TUMOR IDENTIFIED. RESULTS DISCUSSED WITH DR. IN THE OPERATING ROOM. RUN DATE. RUN TIME: RUN USER. SPEC #: PHOTO IXOCUMENITATION. Image. ( signature on file).

expanded version (tokens=2144) : 
 Histological classification: 
- Invasive ductal carcinoma (NOS)
- High-grade ductal carcinoma in situ (DCIS)

Subtype: Basal 

Description of necrosis: Comedo necrosis present

Tumor infiltrating lymphocytes: Not mentioned 

Histological grade: Grade 3 

Nuclear grade: Score 3 

Lymphovascular invasion: None identified

Calcification: Not mentioned 

Receptor Status: 
- Estrogen Receptor (ER): Negative 
- Progesterone Receptor (PR): Positive (3% tumor cells with weak staining intensity)
- Human Epidermal Growth Factor Receptor 2 (HER2/neu): Equivocal (Score 2+)

Ancillary testing results: 
- In Situ Hybridization: Amplified 
- Average Number HER2 Gene Copies Per Cell: 5.4 
- Average Number of Chromosome 17 Per Cell: 2.0 

Other findings: The tumor focally involves inked deep margin adjacent to the skeletal muscle tissue. Healing wound reaction consistent with previous core needle biopsy. 

Overall, the report describes a 3.5cm basal subtype invasive ductal carcinoma with associated high-grade ductal carcinoma in situ, located in the right breast. The tumor shows nuclear pleomorphism and has a high mitotic rate, giving it a histological grade of 3. The report does not mention any tumor infiltrating lymphocytes. The tumor abuts the ink

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2297) : 
 Report: A 3.5cm basal subtype invasive ductal carcinoma with high-grade DCIS is present in the right breast. The tumor has a histological grade of 3 and shows nuclear pleomorphism and high mitotic rate. No lymphovascular invasion is identified. ER is negative, PR is positive (3% tumor cells), and HER2/neu status is equivocal. No tumor infiltrating lymphocytes are mentioned, and there is focal involvement of the inked deep margin adjacent to skeletal muscle tissue.

