prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, RUN DATE. RUN TIME. RUN USER: LOC: AGE/SX: ROOM: REG DR: BED: SPEC # : RECD: COLL: TIME IN FORMALIN: hrs. COLD ISCHEMA TIME. mins. CLINICAL INFORMATION: Pre-Op Diagnosis: Right breast mass. Remarks: : Specimen (s) : A. Right breast needle localized lumpectomy for immediate gross. evaluation. B. Sentinel lymph node. MICROSCOPIC DIAGNOSIS. A. RIGHT BREAST (EXCISION WITH NEEDLE LOCALIZATION) : INVASIVE DUCTAL CARCINOMA, 1.7 CM GREATEST DIMENSION. MARGINS APPEAR UNINVOLVED. SEE COMMENT FOR SYNOPTIC REPORT. B. SENTINEL LYMPH NODE. RIGHT AXILLA (BIOPSY) : NO METASTASIS IN ONE LYMPH NODE. COMMENT( (S). SURGICAL PATHOLOGY CANCER CASE SUMMARY - CAP APPROVED. Procedure: Excision with wire-guided localization. Lymph Node Sampling: Sentinel lymph node (s). Specimen Laterality: Right. Histologic Type: Invasive ductal carcinoma. Tumor Size: Greatest dimension of largest focus of invasion >1. mm: 17 mm. Histologic Grade (Nottingham) : Glandular: Score 2. Nuclear Pleomorphism: Score 3. Mitotic Rate: Score 1. Overall Grade Grade 2. Tumor Focality: Single focus of invasive carcinoma. Ductal Carcinoma In Situ (DCIS) : DCIS is present negative for extensive intraductal. component (EIC). Architectural Patterns: Comedo. Cribriform. Nuclear Grade: Grade III (high). Necrosis: Present, central (expansive "comedo". necrosis). Margins: Invasive Carcinoma: : Margins uninvolved by invasive. RUN DATE : RUN TIME : RUN USER: SPEC #: COMMENT (s). carcinoma. Distance from closest margin: 2 mm. DCIS: Margins uninvolved by DCIS. Distance from closest margin: 5 mm. Lymph Nodes. Number of sentinel lymph nodes examined 1. Total number of lymph nodes examined (sentinel and. nonsentinel) : 1. Number of lymph nodes with metastases: 0. Method of Evaluation of Sentinel Lymph Nodes: H&E, multiple levels, immunohistochemistry. Lymph-Vascular Invasion : Not identified. Pathologic Staging: Primary Tumor pT1c. Regional Lymph Nodes: Modifier: (sn). Category: pN0(i-). Distant Metastasis: Not applicable. Ancillary Studies: Performed on. ER: Negative (<1% of tumor cells with nuclear. positivity). PR: Negative <1% of tumor cells with nuclear. positivity). HER2 Immunoperoxidase Studies: Equivocal (Score 2+). In Situ Hybridization for HER2 (FISH or CISH) : Not amplified (HER2 gene copy <4.0 or ratio <1.8). GROSS DESCRIPTION: A. This specimen is received in the fresh state from the operating room for immediate. gross evaluation of the surgical margins and for specimen x-ray. Specimen x-ray is. performed as requested demonstrating centrally a metallic clip. the radiographic target. lesion The specimen consists of a portion of breast tissue which measures 7.5 x 6 x 2 cm. À needle is situated in the specimen. The margins have not been differentially tagged. Blue ink is applied to the margins. Sections reveal a firm, tan tumor measuring 1.7 x 1.5. x 1.5 cm located 3 mm from the nearest surgical margin. À representative section of the. tumor is removed by aseptic technique and submitted for tumor banking. The following. sections are submitted. 1-5. tumor sectioned and totally submitted, blue ink on margins. 6-8 -. representative breast and margins. B. This specimen in the fresh state is a soft, tan lymph node measuring 12 x 10 x 7 mm,. sectioned and totally submitted as block B1. RUN DATE : RUN TIME: RUN USER : SPEC # : MICROSCOPIC DESCRIPTION: A. Sections of the breast tumor demonstrate invasive ductal carcinoma with focal apocrine. features, combined histologic grade 2 of 3. DCIS is present exhibiting comedo and. cribriform growth patterns with necrosis and a high nuclear grade. The DCIS does not. appear extensive. Nearby breast tissue uninvolved by tumor demonstrates at least one. radial sclerosing lesion and foci of ductal epithelial hyperplasia, focally atypical. The. inked margins appear uninvolved. See the comment for a synoptic report. INTRAOPERATIVE CONSULTATION: A. IMMEDIATE GROSS EVALUATION RIGHT BREAST MASS: RADIOGRAPHIC TARGET LESION PRESENT BY SPECIMEN X-RAY. SURGICAL MARGINS APPARENTLY FREE OF TUMOR, 2 MM FROM TUMOR. PHOTO. Image. Image. (signature on file).

expanded version (tokens=1492) : 
 Histological classification: Invasive ductal carcinoma.

Subtype: Luminal A.

Tumor size: Greatest dimension of largest focus of invasion >1. mm- 17 mm.

Histological grade: Glandular: Score 2. Nuclear Pleomorphism: Score 3. Mitotic Rate: Score 1. Overall Grade Grade 2.

Nuclear grade: Grade III (high).

Lymphovascular invasion: Not identified.

Calcification: Not mentioned.

Receptor status: ER and PR both are negative. HER2 status is equivocal (Score 2+).

IHC and any other ancillary testing results: In Situ Hybridization for HER2 (FISH or CISH) is not amplified (HER2 gene copy <4.0 or ratio <1.8).

Other important information: Tumor Focality: Single focus of invasive carcinoma. Ductal Carcinoma In Situ (DCIS): DCIS is present negative for extensive intraductal component (EIC). Architectural Patterns: Comedo. Cribriform. Necrosis: Present, central (expansive "comedo" necrosis). Margins: invasive carcinoma margins uninvolved by invasive carcinoma. Distance from the closest margin: 2 mm. DCIS margins uninvolved by DCIS. Distance from the closest margin: 5 mm. Lymph Nodes- Number of sentinel lymph nodes examined 1. Total number of lymph nodes examined (sent

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1630) : 
 The report shows that the patient has Invasive ductal carcinoma subtype Luminal A with a tumor size of 17mm and grade II. Necrosis is present, along with Comedo and Cribriform architectural pattern. The ER, PR are negative and HER2 status equivocal. Lymphovascular invasion was not identified, Calcification not mentioned. Margins were uninvolved, and 1 lymph node examined with no metastasis found.

