prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, FINAL PATHOLOGIC DIAGNOSIS. A. Lymph node, sentinel #1, right axillary, excision: - One lymph node, negative for metastatic carcinoma (0/1). - Biopsy site changes identified. B. Lymph node, sentinel #2, right axillary, excision: - One lymph node, negative for metastatic carcinoma (0/1). C. Lymph node, sentinel #3, right axillary, excision: - One lymph node, negative for metastatic carcinoma (0/1). D. Lymph node, sentinel #4, right axillary, excision: - One lymph node, negative for metastatic carcinoma (0/1). E. Breast, right, partial mastectomy: - Invasive lobular carcinoma, see breast pathologic. parameters. - Margins of excision free of tumor, distance to the closest margin >2 mm. to superior and anterior. - Lobular intraepithelial neoplasia (LCIS), classic type. - Atypical ductal hyperplasia. - Previous biopsy site identified with extensive fat necrosis. - Flat epithelial atypia, focally associated with microcalcifications. - Sclerosing adenosis, focally associated with microcalcifications. - Microcalcifications in benign ductal and stroma. - Fibrocystic changes with cystic apocrine metaplasia. F. Breast, additional superior medial margin, excision: - Focal atypical ductal hyperplasia. - Lobular intraepithelial neoplasia (ALH/LCIS). - Focal flat epithelial atypia. to Sclerosing adenosis focally associated with microcalcifications. - Microcalcifications in benign ductules and stroma. - Fibrocystic changes with cystic apocrine metaplasia. - Duct ectasia. Breast Pathologic Parameters. Specimen E: Breast, right, partial mastectomy. 1. Invasive carcinoma: A. Size: Gross measurement: 1.6 x 1.5 X 1.4 cm. B. Composite histologic (modified SBR) grade II. - Architecture: 3. - Nuclear grade: 2. - Mitotic count: 1. C. Associated lobular intraepithelial neoplasia (LCIS): - Within main mass (forming <5% of tumor volume). - Extending away from main mass. 3. Excisional biopsy margins: Free of tumor. - Invasive carcinoma > 2 mm from anterior and superior margins. - Additional margins greater than 3 mm away. 4. Blood vessel and lymphatic invasion: Not definitively identified. 5. Axillary lymph nodes: Negative for tumor (0/4). 6. Special studies (see. - Strong expression of ER in 90% of invasive tumor nuclei. - Strong expression of PR in 50% of invasive tumor nuclei. - Her2/neu antigen (FISH) Not amplified. Ratio 1.5. 7. pTNM: pT1c, NO(sn), MX. Clinical History: The patient is an. year old female with a history of biopsy proven grade Il. ILC of the right breast who undergoes right breast needle localization. lumpectomy and right axillary sentinel node dissection. Most recent breast. imaging on. showed in the right breast at the 10 o' clock position an. irregularly shaped heterogenous enhancing mass with irregular margins and. metallic clip artifact at mid depth measuring 1.4 X 1.2 X 1.2 cm representing. the biopsy proven malignant lesion. Posterior to that main mass was a focal. non-mass like enhancement measuring 1.6 x 1.1 cm suspicious for extension of the. disease with a total extent of 2.8 cm. Comment. Part E: The tumor reveals a mixed ductal and lobular morphologic appearance,. however, immunohistochemical stains for E-cadherin were performed on. representative areas and supports the presence of a lobular carcinoma. Case presented at multidisciplinary breast conference on. Specimens Received: A: Right axillary sentinel node#1. B: Right axillary sentinel node #2. C: Right axillary sentinel node #3. D: Right axillary sentinel node #4. E: Right breast partial mastectomy. F: Additional superior medial margin. Gross Description: The specimen is received in six containers each labeled with the patient' S name. and medical record number. A. Container A is further designated as 1. Right axillary sentinel node #1.'. Received fresh and placed in formalin is a 1.5 x 1.2 x 1.0 cm firm, rubbery. lymph node that is dissected and entirely submitted in cassette A1. B. Container B is further designated as 2. Right axillary sentinel node #2. Received fresh and placed in formalin is a 0.7 X 0.6 X 0.4 cm tan, rubbery lymph. node candidate that is entirely submitted in cassette B1. C. Container C is further designated as '3. Right axillary sentinel node #3.'. Received fresh and placed in formalin is a 0.9 X 0,7 X 0.4 cm tan, rubbery lymph. node candidate. It is entirely submitted in cassette C1. D. Container D is further designated as 14. Right axillary sentinel node #4. Received fresh and placed in formalin is a 0.6 x 0.5 x 0.2 cm tan, rubbery lymph. node candidate that is entirely submitted in cassette D1. E. Container E is further designated as '5. Right breast partial mastectomy'. with the paper work additionally designating 1 stitch = lateral. Received fresh. and placed in formalin is a 99.5 gram, 8.5 cm (superior to inferior) X 10.0 cm. (medial to lateral) X 3.5 cm (anterior to posterior) breast lumpectomy specimen. on a radiographic grid with a corresponding x-ray film. There is a metallic. clip located in the center of a spiculated irregularly shaped mass which. corresponds to C3-C4, D3-D4 and D5. The metallic clip is located in D4. There. is a questionable extension of the mass into grids E3-E4. A wire extends through. the center of this mass entering at B5 and terminating at F1. The specimen is. received with two sutures, long designating lateral and short designating. superior. The margins are inked as follows: superior blue, inferior green,. anterior black, posterior red, lateral violet and medial yellow. The. specimen is serially sectioned from lateral to medial into 14 slices to reveal a. 1.6 X 1.5 X 1.4 cm firm, white poorly circumscribed mass extending from slice 6. to slice 9. There is a metallic clip found on the center of this mass in slice. 8. The mass approaches the anterior margin within 0.3 cm (slice 9) and the. posterior margin within 0.6 cm (slice 7). Additionally, the lesion is 3.5 cm. from the inferior margin and 0.7 cm from the superior margin. The mass is. greater than 2 cm from both the medial and lateral margins. The wire terminates. in slice 11. The remainder of the breast tissue consists of grossly. unremarkable yellow, lobulated adipose tissue. Representative sections are. submitted as follows: E1: mass with clip (slice 8) showing approach to posterior and superior margins. E2-E3: anterior margin from slice 8. E4-E5: mass in slice 7 showing closest approach to posterior margin. E6-E7: mass in slice 6 demonstrating biopsy site changes. E8: inferior margin from slice 6. E9-E10: mass in slice 10 showing nearest approach to anterior margin. E11: posterior margin slice 7. E12-E13: posterior inferior margin slice 8. E14: posterior margin slice 9. E15: anterior margin slice 9. E16: anterior margin slice 8. E17: anterior superior margin slice 6. E18-E20: sections immediately lateral to mass (slice 5). E21-E22: sections immediately medial to mass (slice 10). E23: grossly unremarkable breast parenchyma slice 3. E24: grossly unremarkable breast parenchyma slice 12. E25: lateral margin serially sectioned (slice 1). E26: medial margin serially sectioned (slice 14). F.Container F is further designated as '3. Additionalsuperior medial margin,. short stitch marks new true margin.' Received fresh is a 38.0 gram portion of. yellow, lobulated fibroadipose tissue that measures 8.5 X 6.0 X 1.5 cm. The. short stitch designates the new true margin. This aspect is inked blue. The. specimen does not have any further orientation. The specimen is serially. sectioned to reveal that is primarily composed of yellow, lobulated adipose. tissue with a region of enhanced firm, white fibrosis measuring 2.4 X 1.5 X 1.5. cm that appears to abut the new true margin. The specimen is entirely submitted. sequentially in cassettes F1-F23 with the fibrotic region in F9-F14. Pathologist Sign Out:

expanded version (tokens=2438) : 
 The breast pathology report indicates the following findings:

1. Histological classification: Invasive lobular carcinoma, with a mixed ductal and lobular morphologic appearance. Subtype LumA.

2. Necrosis: No mention of necrosis in the report.

3. Tumor infiltrating lymphocytes: No mention of tumor infiltrating lymphocytes in the report.

4. Histological grade: Modified SBR grade II - Architecture: 3, Nuclear grade: 2, Mitotic count: 1.

5. Lymphovascular invasion: Not definitively identified.

6. Calcification: Multiple microcalcifications, some focally associated with sclerosing adenosis and flat epithelial atypia.

7. Receptor status: Strong expression of ER in 90% of invasive tumor nuclei, strong expression of PR in 50% of invasive tumor nuclei, and Her2/neu antigen (FISH) not amplified (ratio 1.5).

8. IHC and ancillary testing results: Immunohistochemical stains for E-cadherin supports the presence of a lobular carcinoma. Additional ancillary studies not mentioned in the report.

9. Other findings: Biopsy site changes identified, lobular intraepithelial neoplasia (LCIS), classic type, atypical ductal hyperplasia, fibrocystic changes with cystic apocrine metaplasia, and duct ectasia identified in the breast tissue.

10. Excision

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2627) : 
 Report Summary: LumA subtype invasive lobular carcinoma with mixed ductal and lobular morphologic appearance was identified in the right breast. The tumor is grade II, ER strongly expressed in 90% of invasive tumor nuclei, PR strong expression in 50%, and Her2/neu antigen (FISH) not amplified. No necrosis or tumor infiltrating lymphocytes were detected, and lymphovascular invasion was not identified. Multiple microcalcifications were detected, and biopsy site changes as well as other lesions such as LCIS, atypical ductal hyperplasia, fibrocystic changes with cystic apocrine metaplasia, and duct ectasia were identified in the breast tissue.

