prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Path No.: Date Obtained: (Age: ). Date Received: F. See Addendum/Procedure. SPECIMEN: A:Subnipple tissue, right breast, excision. B:Lymph node, right axilla sentinel node, biopsy. C:Lymph node, right axilla sentinel node #2, biopsy. D:Breast, right, total mastectomy. E:Skin, right breast, excision. DIAGNOSIS(ES): A. Subnipple tissue, right breast, excision: Nipple ducts with atypical micropapillary hyperplasia. No carcinoma seen. B. Lymph node, right axilla sentinel node, biopsy: Lymph node, bisected and serially sectioned, negative for carcinoma. IHC for cytokeratin is negative. C. Lymph node, right axilla sentinel node #2, biopsy: Lymph node, quadrasected and serially sectioned, single focus of carcinoma seen by light microscopy. and IHC for cytokeratin (focus of < 10 cells, ITC). D. Breast, right, total mastectomy: Infiltrating ductal carcinoma, well differentiated (1+2+1=4/9), spanning 2,0 cm, arising in a background. of ductal carcinoma in situ, intermediate to high grade. Infiltrating ductal carcinoma, separate focus, moderately differentiated (3+3+1=719), spanning 0.6 cm. Extensive ductal carcinoma in situ, solid, cribriform and micropapillary type, with necrosis and. microcalcification, seen on 15 of 26 slides and extending to within 0.1 cm of deep margin. The. micropapillary DCIS is seen in the nipple duct sections. Lobular carcinoma in situ, monomorphic type. Intraductal papillomas and sclerosing adenosis with microcalcification. Fibroadenoma. E. Skin, right breast, excision: Fragments of skin. CLINICAL INFORMATION: Right breast cancer,. GROSS DESCRIPTION;. The specimen is received in five parts. Part A is received fresh from the operating room for frozen section diagnosis in a container labeled with the patient's. name and "Rt subnipple tissue R/O cancer". It consists of one piece of red soft tissue measuring 1.1 x 0,9 X 0.3 cm. The specimen is entirely submitted in one cassette labeled AFS. Part B is received fresh from the operating room for frozen section diagnosis in a container labeled with the patient's. name and "Right axillary sentinel lymph node #1". It consists of one piece of fatty tissue measuring 3.2 x 1.4 x 0.8 cm. One lymph node is palpated measuring 1.8 cm in greatest dimension. The lymph node is bisected. The specimen is. entirely submitted in four cassettes labeled BFS1-BFS2, B1 and B2. Please note: Three levels and cytokeratin stains. are ordered for the lymph node only. Legend: BFS1-BFS2 = frozen section-lymph node, B1-B2 = remaining tissue. Part C is received fresh from the operating room for frozen section diagnosis in a container labeled with the patient's. name and "Right axillary sentinel lymph node #2". It consists of one piece of fatty tissue measuring 2.8 x 1.9 x 1.1 cm. One. lymph node is palpated measuring 2.7 cm in greatest dimension. The lymph node is quadrisected. The specimen. is entirely submitted in five cassettes labeled CFS1-CFS4 and C1. Please note: Three levels and cytokeratin stains are. ordered for the lymph node only. Legend: CFS1-CFS4 = frozen section-lymph node, C1 = remaining tissue. Part D is received unfixed in a container labeled with the patient's name and "Right breast mastectomy, stitch short. anterior subnipple tissue, stitch long = lateral". It consists of a right total skin sparing mastectomy specimen measuring. 22.0. x. 14.0. X. 3.5 cm. A short suture is noted indicating the subareolar and a long suture is noted indicating the superior. (as per Dr. the long suture was mistakenly labeled "lateral"). An underlying mass is palpable located 1.0 cm. from. the. subareolar. The subareolar is inked blue, the superficial margin is inked yellow and the deep margin is inked. black. The axillary tissue measures 2.5 x 1.5 x 0.5 cm. No lymph nodes are palpable within it. The. specimen is serially sectioned at closely spaced intervals, revealing an area of white, cystic parenchyma measuring. 6.0 x 4.0 x 2.5 cm located in the center, 0.5 cm from the deep margin and 0.2 cm from the superficial margin. Within. the cystic parenchyma is a firm, poorly circumscribed, white-tan mass measuring 2.0 x 2.0 x 1.5 cm which comes to. within 0.6 cm from the deep margin and 1.3 cm from the superficial margin. At least four scattered yellow-white nodules. measuring from 0.5 cm to 0.8 cm in diameter are also seen within the cystic parenchyma located 0.3 cm from the. deep. margin and 1.5 cm from the superficial margin and at least 1.0 cm from the mass. The remainder of the specimen is. composed of a moderate amount of breast tissue (60%) and a moderate amount of yellow fatty tissue (40%). Also. received in the container is one irregular piece of soft, fibrofatty, yellow-red tissue measuring 4.0 x 3.0 x 1.0 cm. On cut. surface, no discrete lesions or lymph nodes are identified. Representative sections are submitted in 26 cassettes. labeled D1-D26. Please note: The specimen was placed in formalin at. LEGEND: D1-D2 = Submucosal area. D3-D4 = Mass with adjacent deep margin. D5-D7 = Remaining portion of mass. D8 = Superficial margin closest to mass. D9-D10 = Nodule closest to mass with adjacent surrounding tissue and deep margin. D11 = Remaining portion of nodule with adjacent surrounding tissue. D12-D15 = Surrounding nodules in cystic parenchyma. D16-D17 = Cystic parenchyma. D18-D19 = Upper inner quadrant. D20-D21 = Lower inner quadrant. D22-D23 = Lower outer quadrant. D24-D25 = Upper outer quadrant. D26 = Fibrofatty tissue also received in the container. Part E Is received unfixed in a container labeled with the patient's name and "Skin from mastectomy R breast". It. consists of a strip of rubbery, tan-brown skin measuring 11.6 x 0.7 x 0.2 cm. Representative sections are submitted in. one cassette labeled E1. Please note: The specimen was placed in formalin at. INTRAOPERATIVE CONSULTATION: AFS: Benign breast tissue and large ducts. No carcinoma seen. BFS1, BFS2: No carcinoma seen. CFS1, CFS2: No carcinoma seen. CFS3, CFS4: No carcinoma seen. Performed by: Resident: Interpreted by: Attending: MICROSCOPIC DESCRIPTION: TYPE OF SPECIMEN: Right total mastectomy with sentinel node dissection. II. LOCATION OF THE TUMOR: Central. III. TYPE OF NEOPLASM: Carcinoma, Invasive, Ductal - NOS (Nodule 1). Well Differentiated, Total score 4. (Tubule Score 1, Nuclear Grade Score 2, Mitotic Score 1). TUMOR SIZE: The tumor's greatest dimension 2.0 cm. Carcinoma, Invasive, Ductal - NOS (Nodule 2). Moderately Differentiated, Total score 7. (Tubule Score 3, Nuclear Grade Score 3, Mitotic Score 1). TUMOR SIZE: The tumor's greatest dimension 0.6 cm. Ductal carcinoma in situ, nuclear grade 3, widespread 30%. QUANTITATION: Ductal carcinoma in situ is present in 15 of 26 slides of breast. Intraductal solid subtype, cribriform, comedo, micropapillary/. VI. VASCULAR SPACE INVASION: Present in lymphatics. VII. CALCIFICATION: Present in both malignant and benign areas. VIII. NIPPLE: Ducts involved by DCIS. IX. SKIN: Present, uninvolved by cancer. X. ADJACENT BREAST TISSUE: Cystic disease, proliferative with atypia. MARGINS: Tumor distance from closest margin DCIS- <0.1 cm fromm deep margin. XII. AXILLARY LYMPH NODES: Sentinel - 2. XIII. POSITIVE LYMPH NODES: Sentinel - ITC only. XV. PATHOLOGIC STAGING (pTNM) AJCC 7th Edition: Reflects staging only. of the current specimen. Ultimate. staging responsibility rests with the primary physician. pT1c: Tumor more than 1.0 cm but not more than 2.0 cm in greatest dimension. pNO(ITC,i+): No regional lymph node metastasis on H & E histologically, (ie. Individual tumor cells seen,. none greater than 0.2 mm, positive IHC. COMMENT(S): Case shown at. This report has been reviewed electronically and signed on. Interpreted by: Attending: The diagnosis was rendered by the attending pathologist. Receptor Expression Analysis. INTERPRETATION. Test Performed on formalin fixed paraffin embedded section of: mastectomy. The results are for invasive carcínoma #1. Specimen part: D. Slide#. D3. Fixation: adequate. This tumor is considered positive for estrogen receptor expression (21 % of the cells are positive). The. specimen was adequate for evaluation for ER as per ASCO/CAP guidelines 2010. Approximately 75 % of the. carcinoma cell nuclei stain with an immunohistochemical stain utilizing an anti-estrogen receptor antibody. ) with an average intermediate intensity. This tumor is considered positive for progesterone receptor expression (> 1 % of the cells are positive). The. specimen was adequate for evaluation for PR as per ASCO/CAP guidelines 2010, Approximately 80 % of the. carcinoma cell nuclei stain with an immunohistochemical stain utilizing an anti-progesterone receptor antibody. ) with an average strong intensity. Equivocal/indeterminate for HER2 expression. Her-2/neu over-expression has been evaluated, on a formalin fixed. paraffin embedded section, using the. (proprietary kit). Using the ASCO/CAP scoring criteria, the. score is: 2. Invasive carcinoma #2: This tumor is considered positive for estrogen receptor expression (>1 % of the cells are positive). The. specimen was adequate for evaluation for ER as per ASCO/CAP guidelines 2010, Approximately 100 % of the. carcinoma cell nuclei stain with an immunohistochemical stain utilizing an anti-estrogen receptor antibody. SP1) with an average strong intensity. This tumor is considered positive for progesterone receptor expression @ 1 % of the cells are positive). The. specimen was adequate for evaluation for PR as per ASCO/CAP guidelines 2010. Approximately 100 % of the. carcinoma cell nuclei stain with an immunohistochemical stain utilizing an anti-progesterone receptor antibody. 1E2) with an average strong intensity. Positive for HER2 overexpression. Her-2/neu over-expression has been evaluated, on formalin fixed paraffin. embedded sections, using the. (proprietary kit). Using the ASCO/CAP scoring criteria, the. score: 3. This procedure/addenda has been electronically reviewed and signed on. Interpreted by: Attending: Note: Immunochemistry testing performed at. was developed and ils performance characteristics determined by the. These tests were interpreted in conjunction with externel positive and internal negative controis, unless otherwise noted, It has not been cleared or approved by the US. FDA. This test is used for clinical purposes only. It should not be regarded as investigational or for research. END OF REPORTI.

expanded version (tokens=3094) : 
 Based on the breast pathology report, the main points are as follows:

1. Histological Classification:
- Subnipple tissue, right breast, excision: Atypical micropapillary hyperplasia, no carcinoma seen.
- Lymph node, right axilla sentinel node, biopsy: Negative for carcinoma.
- Lymph node, right axilla sentinel node #2, biopsy: Single focus of carcinoma, less than 10 cells (ITC).
- Breast, right, total mastectomy: Infiltrating ductal carcinoma (IDC), well differentiated (4/9) and moderately differentiated (7/9).
- DCIS: Extensive, solid, cribriform, and micropapillary type with necrosis and microcalcification, involving 15 of 26 slides.
- Lobular carcinoma in situ (LCIS), monomorphic type.
- Intraductal papillomas and sclerosing adenosis with microcalcification.
- Fibroadenoma.

2. Necrosis: Necrosis is observed in the extensive ductal carcinoma in situ (DCIS) component.

3. Tumor Infiltrating Lymphocytes: No mention of tumor infiltrating lymphocytes in the report.

4. Histological Grade:
- IDC (Nodule 1): Well differentiated (tubule score 1, nuclear grade score 2, mitotic score 1).
- IDC (Nodule 2): Moderately differentiated (tubule score 3

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3270) : 
 Histological report: LumA subtype. Right total mastectomy revealed well-differentiated (4/9) and moderately differentiated (7/9) infiltrating ductal carcinomas. Extensive ductal carcinoma in situ (DCIS) with necrosis and microcalcification seen on 15 of 26 slides. Lobular carcinoma in situ (LCIS), papillomas, and sclerosing adenosis present. No tumor infiltrating lymphocytes mentioned. Necrosis observed in DCIS. ER+ (75%), PR+ (>1%), HER2 status inconclusive (score 2 for one tumor, score 3 for the other).

