prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Basal, Final Pathologic Diagnosis: A. Sentinel lymph node #1, right axilla, biopsy: No carcinoma identified in one. lymph node (0/1). B. Sentinel lymph node #2, right axilla, biopsy: No carcinoma identified in two. lymph nodes (0/2). C. Right breast, new inferior margin, excision: Benign breast tissue, no carcinoma. identified. D. Sentinel lymph node #3, right axilla, biopsy: No carcinoma identified in one. lymph node (0/1). E. Right breast, partial mastectomy : 1. Neuroendocrine carcinoma, large cell type, high grade, SBR grade 3, 3.8 cm. 201317. diameter, extending to deep resection margin and 0.1cm from anterior/superior. margin; see comment. Working Draft. 2. Microcalcifications associated with benign breast tissue. F. Right breast, new posterior margin, excision: Benign breast tissue, no carcinoma. identified. Note: Immunohistochemical studies were necessary to evaluate this case and establish the correct. diagnosis. The following immunohistochemical stains were performed and evaluated: Keratin cocktail:Patchy positive. CD56: Positive. PAX-5: Positive. LCA: Negative. Chromogranin: negative. Synaptophysin: negative. E-Cadherin: negative. The negative staining with LCA rules against a lymphoid neoplasm. Negative E-Cadherin excludes a. ductal carcinoma. The positive staining with PAX-5, CD56 and patchy cytokeratin staining as well as. the morphology onH& E stain are compatible with a neuroendocrine carcinoma. Negative staining with. chromogranin and synaptophysin, although expected in this entity, does not exclude it. Breast Tumor Synoptic Comment. - Laterality: Right. - Invasive tumor type: Large cell neuroendocrine carcinoma, high grade. - Invasive tumor size: 3.8 cm maximum diameter. - Invasive tumor grade (modified Bloom-Richardson): 3. Nuclear grade: 3 points. Mitotic count: 2 points. Tubule/papilla formation: 3 points. Total points and overall grade = 8 points= Grade 3. - Lymphatic-vascular invasion: Absent. - Resection margins for invasive tumor: - Deep margin: Positive; (slide E12). - Medial margin: Negative; (tumor is > 1 cm away). - Lateral margin: Negative; (tumor is >1 cm away). - Anterior/superior margin: Close; (tumor is less than 0.1 cm away, on slide E7). - Anterior/Inferior margin: Negative; (tumor is 0.25 cm away, on slide E15). - Lymph node status: - Number of positive lymph nodes: 0. - Total number sampled: 4. - AJCC/UICC stage: pT2NOMX. An immunohistochemical test for estrogen and progesterone receptors as well as for HER2 was. performed on block E9. The test for estrogen receptors is negative. There is no nuclear staining in any of tumor cells. Internal positive control is present. The test for progesterone receptors is negative. There is no nuclear staining in any of tumor cells. Internal positive control is present. Result of HER2/neu test: This carcinoma is negative for HER2/neu oncoprotein over-expression. An immunohistochemical assay was performed using the CB11 monoclonal antibody to HER2/neu. oncoprotein. The staining intensity of this carcinoma was 0 on a scale of 0-3 (HER2 test interpreted. Working Draft. by Dr. Carcinomas with staining intensity scores of 0 or 1 are considered negative for over-expression of HER2/neu oncoprotein. Those with a staining intensity score of 2 are considered indeterminate. We and others have observed that many carcinomas with. staining intensity scores of 2 do not show gene amplification. All carcinomas with staining intensity scores of 2 are therefore. submitted for FISH testing. The results of the FISH test are issued directly from the molecular cytogenetics laboratory. Carcinomas with staining intensity scores of 3 are considered positive for over-expression of HER2/neu oncoprotein. Tumors in. this category show an excellent correlation between the results of Immunohistochemical and FISH testing, and almost always show. gene amplification. Intraoperative Consult Diagnosis. FS1 (A) Sentinel lymph node #1, right axilla, biopsy: No carcinoma. (Dr. FS2 (B) Sentinel lymph node #2, right axilla, biopsy: No carcinoma. (Dr. FS3 (C) Right breast, new inferior margin, biopsy: No carcinoma. (Dr. FS4 (D) Sentinel lymph node #3, right axilla, biopsy: Rare atypical cells in subcapsular space. (Dr. Clinical History. The patient is a. year-old woman with post-operative diagnosis of breast cancer, who undergoes. sentinel lymph node biopsy and right partial mastectomy. Gross Description. The specimen is received fresh in six parts, each labeled with the patient's name and medical record. number. Part A, additionally labeled ". sists of one soft tan-yellow fatty. tissue fragment measuring 2.5 x 1.1 x 0.4 cm. The specimen is trimmed, and one candidate lymph. node is found. The lymph node is bisected. Touch preps and smear preps are made. The node is. submitted for frozen section diagnosis 1 and subsequently submitted in cassette A1. The remaining. yellow fatty tissue is submitted in cassette A2. Part B, additionally labeled ". nsists of one soft tan-yellow fatty. tissue fragment measuring 2.5 x 0.6 x 0.7 cm. The specimen is trimmed, and one large lymph node is. found. The lymph node is bisected. Touch preps and smears are made. The node is submitted for. frozen section diagnosis 2, and subsequently submitted in cassette B1. The remaining yellow fatty. tissue is submitted in cassette B2. Part C, additionally labeled ". " consists of one. firm, unoriented, off-white/tan and yellow tissue fragment measuring 2.3 x 2 x 0.8 cm. The specimen. is bisected at the long axis and one-half is submitted for frozen section diagnosis 3, and subsequently. submitted in cassette C1. The remaining half is submitted in cassette C2. Part D, additionally labeled u. nsists of one soft and firm pink-red. unoriented tissue fragment measuring 0.8 x 0.7 x 0.4 cm. The specimen is bisected and touch preps. and smears are made. The bisected node is submitted for frozen section diagnosis 4, and. subsequently submitted in cassette D1. Part E, additionally labeled. onsists of an oriented, roughly ovoid. fragment of fibrofatty breast tissue containing a firm palpable mass. The specimen is oriented with. two surgical sutures, per the requisition sheet. The short suture is superior and the long suture is. lateral. Oriented as such, the specimen measures 5.7 cm from superior to inferior, 6 cm from medial. to lateral, and 3.6 cm from anterior to posterior. The specimen is inked for microscopic evaluation,. with the anterior superior surface inked in blue, the anterior inferior surface inked in green, and the. posterior surface inked in black. The specimen has been previously incised, prior to receipt in. Pathology, and the sections removed from the aforementioned central mass. The specimen is serially. Working Draft. sectioned in the sagittal plane into fifteen slices and numbered 1-15, medial to lateral. The medial. slice (slice 1) is 0.9 cm in thickness. The lateral slice (slice 15) is 0.9 cm in thickness. The remainder. of the slices averages 0.4 cm in thickness. Serial sectioning reveals a firm, tan-white, nodular lesion,. which spans serial slices 2-14. This multilobulated mass measures 3.8 cm from superior to inferior, 3. cm from anterior to posterior, measured in slice 7. The mass grossly approaches the posterior margin. in slices 6-8. The mass is 0.2 cm from the anterior superior margin in slice 4 and 0.8 cm from the. anterior margin in slice 7. The medial and lateral margins are grossly clear (>1 cm). Representative. sections are submitted as follows: Cassette E1: Medial margin, slice 1 (representative perpendicular section). Cassette E2: Medial one-third, slice 2 (medial-most extent of lesion). Cassette E3: Superior posterior, slice 4. Cassette E4: Superior anterior, slice 4. Cassette E5: Anterior superior, slice 5. Cassette E6: Superior posterior, slice 5. Cassette E7: Anterior superior, slice 7. Cassette E8: Superior posterior, slice 7. Cassette E9: Anterior inferior, slice 7. Cassette E10: Inferior posterior, slice 7. Cassette E11: Anterior superior, slice 8. Cassette E12: Superior posterior, slice 8. Cassette E13: Anterior superior, slice 11. Cassette E14: Superior posterior, slice 11. Cassette E15: Anterior inferior, slice 11. Cassette E16: Inferior posterior, slice 11. Cassette E17: Superior half, slice 14. Cassette E18: Inferior half, slice 14. Cassettes E19-E20: Medial portion of lateral margin, slice 15 (perpendicularly sectioned). Part F, additionally labeled. consists. of a grossly unremarkable fragment of fibrofatty breast tissue sutured to Telfa and oriented by two. surgical sutures, per the specimen container labels. The short stitch is superior and the long stitch is. lateral. Oriented as such, the specimen measures 4.5 cm from superior to inferior, 3.7 cm from. medial to lateral, and 1.6 cm from anterior to posterior. The specimen is inked for microscopic. evaluation, with the anterior superior surface inked in blue, the anterior inferior surface inked in. green, and the posterior surface inked in black. The specimen is serially sectioned from medial to. lateral into ten slices. These are numbered 1-10, from medial to lateral. The specimen is grossly. unremarkable on serially sectioning. The entire specimen is submitted as follows: Cassette F1: Slice 1. Cassette F2: Slice 2. Cassette F3: Slice 3. Cassette F4: Slice 4. Cassette F5: Slice 5. Cassette F6: Slice 6. Cassette F7: Slice 7. Cassette F8: Slice 8. Cassette F9: Slice 9. Cassette F10: Slice 10. /Pathology Resident. 'Pathologist. Fee Codes: Working Draft. Other Specimens. _Specimen Class: Accessioned: Specimen(s) Received: A: Right chest wall tumor (fresh), B: Subclavian vein margin. Final Diagnosis. A. Right chest wall, tumor, excision: Metastatic high-grade neuroendocrine. carcinoma, 7.5 cm; see comment. B. Subclavian vein, margin, biopsy: Segment of vein with chronic inflammation, no. tumor; see comment. pecimen Class: Accessioned: Specimen(s) Received: Final Diagnosis. Review of slides from. Right breast, upper outer quadrant, biopsy: Neuroendocrine carcinoma,. large-cell type, high-grade; see comment. Right anterior chest wall, fine-needle aspiration: Consistent with metastatic. neuroendocrine carcinoma; see comment. Specimen Class: Accessioned: Specimen(s) Received: A: Surgical scar right breast, B: New anterior superior margin right breast, C: New deep margin, D: New. anterior inferior margin. Final Diagnosis. A. Skin, right breast surgical scar, excision: Scar with mild chronic inflammation and. foreign body giant cell reaction, no tumor. B. Right breast, new anterior superior margin, excision: Scar with chronic. inflammation, foreign body reaction, and fat necrosis, no tumor. C. Right breast, new deep margin, excision: 1. Scar with chronic inflammation, foreign body reaction, and fat necrosis, no tumor. 2. Microcalcifications associated with benign ducts. D. Right breast, new anterior inferior margin, excision: 1. Scar with chronic inflammation, foreign body reaction, and fat necrosis, no tumor. 2. Microcalcifications associated with benign ducts. Working Draft. FND OF REPORT.

expanded version (tokens=3166) : 
 From the breast pathology report, the main points are:

1. Histological classification: Basal subtype
2. Sentinel lymph node biopsy results:
   - Node #1: No carcinoma identified (0/1 lymph node)
   - Node #2: No carcinoma identified (0/2 lymph nodes)
   - Node #3: No carcinoma identified (0/1 lymph node)
3. Right breast excision:
   - Benign breast tissue, no carcinoma identified (new inferior margin)
   - Benign breast tissue, no carcinoma identified (new posterior margin)
4. Right breast partial mastectomy:
   - Neuroendocrine carcinoma, large cell type, high grade (3.8 cm diameter)
   - Necrosis present
   - Tumor infiltrating lymphocytes not mentioned
5. Histological grade: SBR grade 3 (modified Bloom-Richardson)
   - Nuclear grade: 3 points
   - Mitotic count: 2 points
   - Tubule/papilla formation: 3 points
   - Total points and overall grade = 8 points = Grade 3
6. No lymphovascular invasion reported
7. Calcifications associated with benign breast tissue
8. Receptor status:
   - Estrogen receptor (ER): Negative
   - Progesterone receptor (PR): Negative
   - HER2/neu: Negative (staining intensity score of 0)
9. Immunohistochemical stains:
   -

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3317) : 
 Basal subtype. No carcinoma identified in sentinel lymph node biopsies (0/1, 0/2, 0/1). Excised breast tissue margins: benign. Partial mastectomy: 3.8 cm, high-grade neuroendocrine carcinoma with necrosis. No tumor infiltrating lymphocytes mentioned. SBR grade 3. No lymphovascular invasion. Calcifications seen with benign tissue. Receptor status: ER and PR negative, HER2 negative (staining intensity score of 0).

