prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumB, Final Pathologic Diagnosis: A. Lymph node, left axillary sentinel node #1, excision: No metastatic carcinoma in. one lymph node (0/1). B. Lymph node, left axillary sentinel node # +2, excision: Metastatic carcinoma in one. lymph node with extension into peri-nodal fat (1/1). C. Lymph node, left axillary sentinel node # 3, excision: Metastatic carcinoma in one. lymph node (1/1). D. Lymph node, left axillary non-sentinel node # 1, excision: Metastatic carcinoma in. one lymph node (1/1). Working Draft. E. Lymph node, left axillary non-sentinel node #2, excision: Metastatic carcinoma in. one lymph node (1/1). F. Breast, left, partial mastectomy: 1. Infiltrative ductal carcinoma, SBR grade 2, 1.1 cm in maximum dimension,. margins negative; see comment. 2. Ductal carcinoma in situ, high-grade, solid and comedo types, 1.1 cm in maximum. dimension, intermixed with invasive ductal carcinoma, margins negative. G. Breast, left lateral anterior, excision: Benign breast tissue, no carcinoma. identified. H. Breast, medial superior anterior, excision: Benign breast tissue, no carcinoma. identified. I. Lymph node, left axillary contents, excision: No metastatic carcinoma in eight. lymph nodes (0/8). Note: Breast Tumor Synoptic Comment. - Laterality: Left. - Invasive tumor type: Invasive ductal carcinoma. - Invasive tumor size: 1.1 cm maximum diameter. - Invasive tumor grade (modified Bloom-Richardson): 2. Nuclear grade: 3, 3 points. Mitotic count: <10 mitotic figures/10 HPF, 1 point. Tubule/papilla formation: <10%, 3 points. Total points and overall grade = 7 points = grade 2. - Lymphatic-vascula invasion: Extensive lymphatic-vascular invasion is noted with intra-lymphatic. metastasis noted in lymphatics at least 1 cm from the main tumor. - Perineural Invasion: Not present. - Resection margins for invasive tumor: - Deep margin: Negative; (tumor is 0.2 cm away, on slide F6). - Medial margin: Negative; (tumor is greater than 1 cm). - Lateral margin: Negative; (tumor is greater than 1 cm). - Anterior/superior margin: Negative; (tumor is 0.2 cm away, on slide F6). - Anterior/inferior margin: Negative; (tumor is 0.3 cm away, on slide F4). - Ductal carcinoma in situ (DCIS) type: Comedo and solid. - Ductal carcinoma in situ size: 1.1 cm, intermixed with invasive ductal carcinoma. - Ductal carcinoma in situ nuclear grade: High-grade. - Necrosis in DCIS: Comedonecrosis. - Microcalcifications: Not identified. - Resection margins for ductal carcinoma in situ: - Deep margin: Negative; (tumor is 0.6 cm away, on slide F6). - Medial margin: Negative; (tumor is greater than 1 cm). - Lateral margin: Negative; (tumor is greater than 1 cm). - Anterior/superior margin: Negative; (tumor is 0.25 cm away, on slide F6). - Anterior/inferior margin: Negative; (tumor is 0.25 cm away, on slide F6). - Lobular carcinoma in situ (LCIS): None. - Lymph node status: Positive. - Number of positive lymph nodes: 4. - Total number sampled: 13. - Diameter of largest metastasis: 0.8 cm. Working Draft. - Extranodal extension: Present. - AJCC/UICC stage: pT1cN1MX. An immunohistochemical test for estrogen and progesterone receptors was performed by manual. morphometry on block #. The test for estrogen receptors is positive. There isstrong nuclear staining in 90% of tumor cells. Internal positive control is positive. The test for progesterone receptors is positive. There is moderate nuclear staining in 60% of tumor. cells. Internal positive control is positive. Result of HER2/neu test: This carcinoma is positive for HER2/neu oncoprotein over-expression. An immunohistochemical assay was performed by manual morphometry on block F8 using the CB11. monocional antibody to HER2/neu oncoprotein. The staining Intensity of this carcinoma was 3 on a. scale of 0-3 (HER2 test interpreted by Dr. Carcinomas with staining intensity scores of 0 or 1 are considered negative for over-expression of HER2/neu oncoprotein. Those with a staining intensity score of 2 are considered indeterminate. We and others have observed that many carcinomas with. staining intensity scores of 2 do not show gene amplification. All carcinomas with staining intensity scores of 2 are therefore. submitted for FISH testing. The results of the FISH test are issued directly from the molecular cytogenetics laboratory. Carcinomas with staining intensity scores of 3 are considered positive for over-expression of HER2/neu oncoprotein. Tumors in. this category show an excellent correlation between the results of immunohistochemical and FISH testing, and almost always show. gene amplification. Intraoperative Consult Diagnosis. FS1 (A) Left axillary sentinel lymph node #1, biopsy: No tumor seen. (Tissue section and. cytopreparation) (Dr. FS2 (B) Left axillary sentinel lymph node #2, biopsy: Positive for metastatic carcinoma. (Tissue. section and cytopreparation) (Dr. FS3 (C) Left axillary sentinel lymph node #3, blopsy: Positive for metastatic carcinoma. (Tissue. section and cytopreparation) (Dr. 1. FS4 (D) Left axillary non-sentinel lymph node #1, biopsy: Positive for metastatic carcinoma. (Tissue. section and cytopreparation) (Dr. Clinical History. The patient is a. year-old woman with left breast invasive ductal carcinoma. She undergoes partial. mastectomy. Gross Description. The specimen is received fresh in nine parts, each labeled with the patient's name and medical record. number. Part A is additionally labeled. It consists of a single irregular piece of. soft-firm, pink-red tissue, measuring 0.5 x 0.3 X 0.2 cm. The specimen is bisected, and cytologic. touch and scrape preparations are prepared. The specimen is then entirely submitted for frozen. section diagnosis as FS1, with the frozen section remnant submitted in cassette A1. Part B is additionally labeled. It consists of a single oval piece of soft-to-firm,. red-pink tissue, measuring 0.9 x 0.6 x 0.6 cm. The specimen is bisected, and cytologic touch and. scrape preparations are made. The specimen is then entirely submitted for frozen section diagnosis as. FS2, with the frozen section remnant submitted in cassette B1. Part C is additionally labeled. It consists of a single ovoid piece of soft-to-firm,. Working Draft. pink-red tissue, measuring 0.8 x 0.5 x 0.4 cm. The specimen is bisected, and cytologic touch and. scrape preparations are prepared. I he specimen is then entirely submitted for frozen section. diagnosis as FS3, with the frozen section remnant submitted in cassette C1. Part D is additionally labeled. It consists of a single ovoid piece of. soft-to-firm, pink-red tissue, measuring 1.3 x U.I x 0.5 cm. The specimen is bisected, and cytologic. touch and scrape preparations are prepared. The specimen is then entirely submitted for frozen. section diagnosis as FS4, with the frozen section remnant submitted in cassette D1. Part E is additionally labeled. It consists of a single ovoid piece of firm,. off-white/tan tissue, measuring 1.5 x 0.7 x 0.4 cm. The specimen is bisected and entirely submitted. in cassette E1. Part F is additionally labeled. t consists of. an oriented portion of fat, measuring 10.3 (anterior- posterior) x 7.4 (medial-lateral) x 6.4. (superior-inferior) cm and weighing 13 gm. There is a 1.1 cm in diameter white-yellow hard mass. with a white homogeneous interior located within the specimen (slices 3-6). This mass abuts the. posterior margin, is 0.6 cm from the anterior-inferior and anterior-superior margins, 1 cm from the. lateral margin, and 7 cm from the medial margin. The specimen is inked so as the anterior-superior. surface is blue, the anterior- inferior surface is green, and the posterior surface is black. A. representative section is taken for tissue banking. The specimen is serially sectioned, from lateral to. medial into thirteen 0.5 cm slices. Representative sections are submitted as follows: Cassette F1: Lateral margin, slice 1, perpendicular. Cassettes F2-F3: Slice 2, two pieces. Cassettes F4-F5: Slice 3, two pieces, mass. Cassettes F6-F7: Slice 4, two pieces, mass. Cassette F8: Representative section of slice 5, mass. Cassette F9: Representative section of slice 6, mass. Cassette F10: Slice 12. Cassette F11: Medial margin, slice 13. perpendicular. Part G is additionally labeled. It consists of a. small fragment of fat, measuring 0.6 x 0.7 x 0.7 cm. A stitch marks a portion of the specimen. indicating the true margin. The specimen is inked so as this true margin is blue, and the rest of the. specimen is black. The specimen is entirely submitted in cassette G1. Part H is additionally labeled. It. consists of a fragment of yellow-white, soft fat, measuring 1 x 0.6 x 0.7 cm. A stitch marks the true. margin of the specimen. The specimen is inked so as this true margin is blue, and the remaining. portion of the specimen is black. The specimen is entirely submitted in cassette H1. Part I is additionally labeled. It consists of a portion of fat measuring 4.2 x 3.8. x 0.9 cm. Multiple pink-tan lymph nodes are noted within the specimen ranging in size from 0.6-1.3. cm in diameter. Many of these nodes are previously bisected or trisected. Representative sections. of. the specimen are taken and submitted as follows: Cassette 11: Six lymph nodes attached. Cassette 12: Two lymph nodes, one bisected and one trisected. 'Pathology Resident. Fee Codes: Working Draft. Other Specimens. Specimen Class: i. Accessioned: Specimen(s) Received: Skin, biopsy, punch bx, right posterior calf. Final Diagnosis. {Final Report Not Signed Out}. (Not Entered}. Specimen Class: Accessioned: Specimen(s) Received: SP Consult. Final Diagnosis. Review. from. Breast, left, 1 o'clock, core needle biopsy: 1. Invasive carcinoma; see comment. 2. Microscopic focus of ductal carcinoma in situ, high nuclear grade; see comment.

expanded version (tokens=2938) : 
 Histological classification:
- Invasive Ductal Carcinoma (IDC) with SBR grade 2, with a size of 1.1 cm in the left breast
- Ductal carcinoma in situ (DCIS) of the high-grade comedo and solid type, intermixed with IDC

Subtype: Luminal B

Description of necrosis:
- Comedonecrosis in DCIS

Tumor Infiltrating Lymphocytes:
- No specific mention of tumor infiltrating lymphocytes

Histological grade:
- Modified Bloom-Richardson grading system: nuclear grade 3 (3 points), mitotic count < 10 mitotic figures/10 HPF (1 point), tubule/papilla formation < 10% (3 points), total points = 7 (grade 2)

Nuclear grade:
- Nuclear grade 3

Lymphovascular invasion:
- Extensive lymphovascular invasion is noted with intra-lymphatic metastasis noted in lymphatics at least 1 cm from the main tumor.

Calcification:
- Microcalcifications not identified

Receptor status:
- Estrogen receptor positive in 90% of tumor cells
- Progesterone receptor positive in 60% of tumor cells
- HER2/neu overexpression

IHC and ancillary testing results:
- IHC test for estrogen and progesterone receptors positive
- HER2/neu test positive (staining intensity score of

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3112) : 
 Report: The patient has been diagnosed with LumB subtype of invasive ductal carcinoma (IDC) with SBR grade 2 in the left breast, measuring 1.1 cm. Ductal carcinoma in situ (DCIS) of high-grade comedo and solid type is also noted intermixed with IDC. There are four positive lymph nodes out of 13 sampled and extensive lymphovascular invasion is noted. Estrogen and progesterone receptor tests are positive while HER2/neu test shows overexpression. Comedonecrosis in DCIS was observed while microcalcifications were not identified in the biopsy specimen.

