prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, I. Specimen #: (Age : ) F Race : WHITE. Physician (s) : AMENDED / ADDENDUM: SPECIMEN: RIGHT BREAST TISSUE. FINAL DIAGNOSIS: BREAST, RIGHT INFERIOR LATERAL RETRO-AREOLA, EXCISION : INFILTRATING LOBULAR CARCINOMA. SURGICAL MARGINS POSITIVE FOR TUMOR. TUMOR SIZE: 0.5 CM BY MICROSCOPY. LOBULAR CARCINOMA IN SITU. PERINEURAL INVOLVEMENT BY CARCINOMA. MICROCALFICIATIONS IDENTIFIED. AJCC STAGING: STAGE I (T1, NX, MX), SEE COMMENT. COMMENT: (visiting pathology resident from. discussed the. above diagnosis with Dr. on. at. AMENDMENT. At the request of the clinician, tumor was evaluated for HER2-neu -. overexpression by immunohistochemical methods (DAKO HercepTest) with. the. following results: HER2/neu overexpression: NEGATIVE (1+). COMMENT: Membranous staining is interpreted on a scale of 0 to 3+ with. positivity defined as 2+ or qreater. Test performed at. Interpretation rendered by. -5. Specimen #: ADDENDUM: HER2/NEU BY FISH = 1.1 NOT AMPLIFIED. TEST: FISH for detection of HER2-neu gene amplification (Path Vision Her2. DNA probe by Vysis) Ratio of Her2-neu over chromosome 17 signals. RANGE FOR INTERPRETATION. Ratio less than 2.0 HER2-neu gene amplification not observed. Ratio equal to or greater than 2.0: HER2-neu gene amplification. observed. ER/PR IMMUNOSTAINS ARE NEGATIVE. C. INICAL DIAGNOSIS AND HISTORY: YO FEMALE WITH SMALL 1X.6CM COMPLEX MASS BY U/S AT INFERIOR/LATERAL. RETROAREOLAR. PRE-OPERATIVE DIAGNOSIS: FIBROUS TISSUE VS MALIGNANCY. POST-OPERATIVE DIAGNOSIS: Post-operative Diagnosis: SAA. GROSS DESCRIPTION: RIGHT BREAST TISSUE "inferior lateral retro-areola" consists of a single. irregularly shaped fragment of fibro fatty tissue, which previously has. been inked and sectioned. When reapproximated, the specimen measures 2 x. 1 x 1 cm. The previous sectioning reveals that the specimen is mostly fat. with admixed fibrous tissue. The specimen is placed in its entirety. in the 5 gray cassettes marked. A1-A5. The specimen was previously. inked blue before being received by this observer.

expanded version (tokens=1009) : 
 The breast pathology report indicates that the patient had a LumA subtype of breast cancer. The final diagnosis was infiltrating lobular carcinoma, which means cancer cells had spread beyond the lobules of the breast. Surgical margins were positive for tumor, suggesting that all cancer cells may not have been removed during the surgical procedure. The tumor size was determined to be 0.5 cm by microscopy, and lobular carcinoma in situ was also detected.

Perineural involvement by carcinoma was found, indicating that cancer cells had invaded nerve fibers around the tumor. Microcalcifications were identified, which can be a sign of breast cancer. The staging of the cancer was determined to be stage I (T1, NX, MX), which means that it is a small tumor and has not spread to the lymph nodes or other organs.

The report states that the tumor was negative for HER2/neu overexpression by immunohistochemical methods. This result was confirmed by HER2/neu gene amplification test using FISH, which showed a ratio of 1.1, indicating no amplification of the gene. ER/PR (estrogen receptor/progesterone receptor) immunostains were negative, meaning the cancer cells do not respond to hormonal therapy.

The clinical diagnosis and history include a 60-year-old female with a small 1x6 cm complex mass at the inferior/lateral retroareolar location. The pre-operative diagnosis was fibrous tissue versus malignancy. The post-operative diagnosis was S

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1139) : 
 Breast cancer pathology report reveals LumA subtype infiltrating lobular carcinoma measuring 0.5 cm. Perineural involvement and microcalcifications were found, and surgical margins were positive for tumor. HER2/neu immunohistochemical and gene amplification tests showed negative results. ER/PR immunostains were negative too. The report suggests stage I breast cancer that is not responsive to hormonal therapy.

