prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Specimen #: F. Race: WHITE. Physician (s) : AMENDED. A: RIGHT BREAST TISSUE B: LEFT AXILLA SENTINEL NODE Site: breast, NOS C50.9. SPECIMEN: C: LEFT BREAST TISSUE. D: LEFT BREAST TISSUE LOWER INNER QUADRANT. FINAL DIAGNOSIS: A. BREAST, RIGHT, MASTECTOMY: - FOCAL USUAL DUCTAL HYPERPLASIA. - FOCAL LACTATIONAL/SECRETORY CHANGE. STROMAL SCLEROSIS AND FOCAL APOCRINE METAPLASIA. - UNREMARKABLE SKIN AND NIPPLE. - NO EVIDENCE OF MALIGNANCY. B. LYMPH NODE, LEFT AXILLA SENTINEL NODE, RESECTION: - ONE LYMPH NODE NEGATIVE FOR TUMOR BY LIGHT MICROSCOPY AND. CYTOKERATIN IMMUNOHISTOCHEMISTRY. C. BREAST, LEFT, MASTECTOMY: WELL DIFFERENTIATED (GRADE I/III) INFILTRATING DUCTAL CARCINOMA. NOTTINGHAM SCORE: 5 OUT OF 9 (TUBULES=2, NUCLEI=2, MITOSES=1). TUMOR SIZE (GREATEST DIMENSION) : 1.9 CM (measured grossly). MICROCALCIFICATIONS: IDENTIFIED WITHIN INTRADUCTAL COMPONENT. AND BENIGN DUCTS. VENOUS / LYMPHATIC INVASION: NOT IDENTIFIED. MARGINS : NEGATIVE - DISTANCE FROM NEAREST MARGIN: 0.4 CM FROM. SUPERFICIAL MARGIN (measured grossly). INTRADUCTAL COMPONENT: DUCTAL CARCINOMA IN SITU, INTERMEDIATE. NUCLEAR GRADE (DCIS, GRADE II) ; SOLID AND CRIBIFORM TYPES WITH. FOCAL INTRALUMINAL NECROSIS AND CALCIFICATIONS. SKIN OR NIPPLE INVOLVEMENT: ABSENT. ESTROGEN RECEPTORS: POSITIVE (please see prior specimen. PROGESTERONE RECEPTORS: POSITIVE (please see prior specimen. HER2 NEU BY IHC: NEGATIVE (please see prior specimen. (see comment). PATHOLOGIC STAGE: pT1cNO (i-)Mx. - ADDITIONAL PATHOLOGIC CHANGES: FOCAL USUAL DUCTAL HYPERPLASIA. Specimen #: FINAL DIAGNOSIS (continued) : D. BREAST, LEFT LOWER INNER QUADRANT, EXCISION. - BENIGN BREAST TISSUE; NEGATIVE FOR TUMOR. Comment: There is no change in the original pathologic diagnosis. This. amendment is issued to reflect a change in the HER2 immunohistochemical. status. The original. report stated that the HER2 was positive. based on the core biopsy material. However, that core biopsy. material has been recently amended to reflect that the HER2 is actually. negative (further supported by confirmatory FISH study showing no. amplification). CLINICAL DIAGNOSIS AND HISTORY: -year-old female with left breast cancer, and strong family. history, desires prophylactic bilateral mastectomy. GROSS DESCRIPTION: A. Received in formalin, labeled with the patient's name,. designated "RIGHT BREAST TISSUE, LONG = LATERAL, SHORT = SUPERIOR". is. a. 300 gram right mastectomy specimen oriented with a short stitch superior,. and long stitch lateral. The specimen measures 16.0 x 16.0 x 3.0 cm, and. displays an 8.5 x 3.0 cm lightly pigmented skin ellipse on the superficial. surface. The centrally located everted nipple measures 1.5 cm and is free. of discharge. The deep margin is inked in black. Serial sections reveal. markedly dense, pink-white, fibrous tissue involving 70% of the cut. surface. The tissue is slightly nodular, however, no discreet mass or. lesion is identified. No lymph nodes are identified. Representative. sections are submitted as follows. Cassette Key. A1: Skin. A2: Upper outer quadrant. A3: Lower outer quadrant . A4: Lower inner quadrant. A5: Upper inner quadrant. A6: : Central. Matched sections of A1 through A6 are submitted in OCT for CBCP protocol. . Specimen #: GROSS DESCRIPTION (continued) : A7: Nipple. A8: Upper outer quadrant. A9: Lower outer quadrant. A10: Lower inner quadrant. All: Upper inner quadrant. 11C11. B. Received in formalin, labeled with the patient's name,. designated "LEFT AXILLA SENTINEL NODE" is a single 1.8 x 1.8 x 0.6 cm. pink-tan lymph node. The lymph node is trisected, and entirely submitted. in cassettes B1 and B2. Matched section of B1 is submitted in OCT for. CBCP protol. C. Received in formalin, labeled with the patient's name,. designated "LEFT BREAST TISSUE, LONG LATERAL, SHORT SUPERIOR" is. a. 284. gram left mastectomy specimen oriented with a short stitch superior and. long stitch lateral. The specimen measures 14.5 cm medial to lateral,. 14. 0 cm superior to inferior, and 2.5 cm anterior to posterior. The. lightly pigmented superficial skin ellipse measures 7.0 x 3.: cm and. displays a centrally located, everted nipple measuring 1.8 x 1.5 x 1.3 cm. The nipple is free of discharge. The deep margin is inked in black,. and. the superficial inferior half is inked in blue. Serial sections reveal. a. 1.9. x 1.6 x 1. 6 cm well defined, pink-tan, gritty, indurated mass in the. lower outer quadrant at the junction of the deep and superficial margins. The mass is located 1.0 cm from the deep margin, and 0.4 cm from the. superficial margin. The remainder of the specimen is composed of 70% of. markedly dense, diffusely nodular fibrous tissue with scattered gray-blue. cysts measuring up to 0.3 cm in greatest dimension. No lymph nodes are. identified. Representative sections are submitted: Cassette Summary : C1: Skin. C2 : Nipple. C3: Mass, lower outer quadrant . C4-C6: - Deep and superficial margins of C3. C7: Mass with superficial margin. C8 : Additional superficial margin. C9: Adjacent normal with cyst (lower outer quadrant) . C10: Upper outer quadrant. C11: Upper inner quadrant. C12: Lower inner quadrant. Matched sections of C1-C3, C7, and C9-C12 are submitted in OCT for CBCP. protocol. C13-C15: Additional representative sections of breast mass. 15CF: Specimen # : GROSS DESCRIPTION (continued) : D. Received in formalin, labeled with the patient's name,. designated "LEFT BREAST TISSUE LOWER INNER QUADRANT" are multiple. fragments of yellow, lobular, adipose tissue. The first fragment measures. 5.! x 3.0 x 0.4 cm. The second fragment measures 5.0 x 2.5 x 0.5 cm. Serial sectioning is remarkable for an area of focal hemorrhage measuring. 0. 4 x 0.3 x 0.2 cm located 0.2 cm from the nearest inked margin. Representative section is submitted in cassette D1. Also noted is a. fibrotic band measuring 0.4 x 0.4 X 0.2 cm abutting the closest inked. margin. Two representative sections are submitted in cassette D2. The. second specimen is inked in blue, and is serially sectioned to reveal. unremarkable, yellow, cut surfaces. Representative sections are submitted. in cassettes D3-D4. 4CF.

expanded version (tokens=2170) : 
 Histological Classification: Well differentiated (Grade I/III) infiltrating ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS, Grade II, solid and cribiform types with necrosis and calcifications).

Subtype: LumA.

Nuclear Grade: Intermediate.

Lymphovascular Invasion: Not identified.

Calcification: Microcalcifications identified within intraductal components and benign ducts.

Receptor Status: Estrogen receptors (ER) and progesterone receptors (PR) are positive.

IHC and other ancillary testing results: HER2 neu by IHC is negative. Confirmatory FISH study showed no amplification.

Tumor infiltrating lymphocytes: Not mentioned.

Margins: Negative with a distance of 0.4 cm from the superficial margin (measured grossly).

Nottingham Score: 5 out of 9 (tubules=2, nuclei=2, mitoses=1).

Additional Pathologic Changes: Focal usual ductal hyperplasia.

Clinical Diagnosis and History:  Year-old female with left breast cancer and strong family history, desires prophylactic bilateral mastectomy.

Specimen:

A: Right Breast Tissue Mastectomy: Focal usual ductal hyperplasia, focal lactational/secretory change, stromal sclerosis, and focal apocrine metaplasia.

B: Left Axilla Sentinel Node: One lymph node negative for tumor by light microscopy, and cytokeratin immunoh

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2336) : 
 The breast pathology report shows a well-differentiated (Grade I/III) infiltrating ductal carcinoma (IDC) with ductal carcinoma in situ (DCIS). Microcalcifications are present within intraductal components and benign ducts. Receptors are positive for estrogen and progesterone and negative for HER2 neu by IHC. The tumor has not invaded the lymphovascular system, and margins are negative at 0.4 cm. Focal usual ductal hyperplasia is the only additional pathologic change identified. A chest wall resection ensures margin negativity.

