prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Specimen # : (Age: Race: Physician (s) : SPECIMEN: A: SENTINEL LYMPH NODE #1 B: LEFT AXILLARY TISSUE. C: LEFT MASTECTOMY D: NEW INFERIOR MARGIN. FINAL DIAGNOSIS: A. SENTINEL LYMPH NODE #1, BIOPSY: - ONE OF TWO LYMPH NODES WITH ISOLATED TUMOR CELLS (ITC) DETECTED BY. CYTOKERATIN IMMUNOHISTOCHEMICAL STAINING, refer to part C. B. SOFT TISSUE, LEFT AXILLA, EXCISION: BENIGN FIBROADIPOSE AND VASCULAR CONNECTIVE TISSUE WITH NERVE. - NO EVIDENCE OF LYMPH NODES. - NEGATIVE FOR MALIGNANCY. C. /. I, MASTECTOMY: i TYPE: INVASIVE LOBULAR CARCINOMA. AISTOLOGIC GRADE: GRADE 2, MODERATELY DIFFERENTIATED. - NOTTINGHAM SCORE: 6 (Tubules= 3, Nuclei 2, Mitoses= 1). TI". IZE (GREATEST DIMENSION) : GREATER THAN 5.0 CM, see comment. ITE (QUADRANT) : OUTER UPPER AND MID. "YPE: INVASIVE LOBULAR CARCINOMA. OLC IC GRADE: GRADE 1, WELL DIFFERENTIATED. NOTTINGHAM SCORE: 5 (Tubules= 3, Nuclei 1, Mitoses= 1). - TUMOR SIZE (GREATEST DIMENSION) : 0.3 CM, measured microscopically. - TUMOR SITE (QUADRANT) : INNER UPPER. - TUMOR FOCALITY: MULTIFOCAL. - TUMOR NECROSIS: NOT IDENTIFIED. - MICROCALCIFICATIONS: PRESENT; ASSOCIATED WITH INVASIVE AND IN SITU. TUMOR AND ALSO NON-NEOPLASTIC TISSUE. - LYMPH-VASCULAR INVASION: PRESENT, slide C6. - MARGINS: NEGATIVE FOR MALIGNANCY. - DISTANCE OF INVASIVE TUMOR FROM NEAREST MARGIN = 0.5 CM, DEEP. - IN SITU COMPONENT: LOBULAR CARCINOMA IN SITU (LCIS). - DISTANCE OF LCIS FROM NEAREST MARGIN = LESS THAN 0.1 CM, DEEP. - LYMPH NODES: ONE OF TWO NODES WITH ISOLATED TUMOR CELLS. - NUMBER OF SENTINEL LYMPH NODES EXAMINED: 2. - NUMBER OF LYMPH NODES WITH MACROMETASTASES: o. - NUMBER OF LYMPH NODES WITH MICROMETASTASES: o. - NUMBER OF LYMPH NODES WITH ISOLATED TUMOR CELLS: 1. - EXTRANODAL EXTENSION: NOT IDENTIFIED. Specimen #: FINAL DIAGNOSIS (continued) : - NIPPLE/ SKIN INVOLVEMENT: NOT IDENTIFIED. ANCILLARY STUDIES (performed on core biopsy. - ESTROGEN RECEPTORS: POSITIVE. - PROGESTERONE RECEPTORS: POSITIVE. - HER 2 NEU by IHC: NEGATIVE. - ADDITIONAL PATHOLOGIC CHANGES: - PRIOR BIOPSY SITE CAVITY/ CHANGES. PATHOLOGIC STAGE: pT3 (m) NO (i+) (sn), (AJCC 7th Edition). D. SOFT TISSUE, NEW INFERIOR MARGIN, EXCISION: - FIBROADIPOSE CONNECTIVE TISSUE AND SCATTERED ATROPHIC BREAST. PARENCHYMA; NEGATIVE FOR MALIGNANCY. Comments: Macroscopically, two masses were noted within the outer upper and outer. mid regions, separated by approximately 1.5 cm. However, sampling of the. intervening tissue confirms the presence of invasive lobular carcinoma. The masses have a similar histologic appearance of invasive lobular. carcinoma, grade 2. Therefore, the upper outer/mid tumors are best. classified as a single mass and staged as pT3. A smaller separate tumor. is noted within the inner upper quadrant. The prior core biopsy. ) and ancillary studies are reviewed. This case received prospective peer review. CLINICAL DIAGNOSIS AND HISTORY: ear-old female with left breast cancer. PRE-OPERATIVE DIAGNOSIS: Breast cancer. POST-OPERATIVE DIAGNOSIS: None provided. Specimen #: GROSS DESCRIPTION: A: Received fresh, labelled with the patient's name. and designated, "Sentinel Node #1" consists of 2.0 x 2.0 x 0.6 cm. irregular portion of red-yellow soft tissue. Sectioning reveals a single. 1.3 x 0.5 x 0.4 cm pink-tan lymph node. The lymph node is bisected and. entirely submitted in 2 cassettes. B: Received in formalin, labeled with the patient's name. and designated, "Left Axillary Tissue" consists of two irregular. shaped fragments of yellow lobular adipose tissue measuring 2.3 and 1.3 cm. in greatest dimension. Sectioning reveals six possible lymph nodes. measuring up to 0.2 cm in greatest dimension each. The specimen is. entirely submitted in three cassettes as follows: B1- -. five. possible. lymph. nodes; B2- one possible lymph node, bisected; B3- remaining adipose. tissue. C: Receivo fresh, labelled with the patient's name. and de. lated, "Left Mastectomy (Long-Lateral; Short-Superior)" consists. of. so gram mastectomy specimen oriented with a short stitch superior. and ung st. lateral. The specimen measures 25.0 cm medial to lateral;. 21.0 cm r. to inferior; and 4.0 cm anterior to posterior. The. light¹. ed superficial skin ellipse measures 24.0 x 14.2 cm and. cm centrally located, everted nipple. No discharge is. The deep margin is inked black. Serial sections reveal a 4.0. x 4. x 3.0 cr poorly defined mass in the mid-outer breast (mass #1) . On. section. t. cut surface is firm, pink-white and shows a 0.3 cm. bloc. opsy cavity. The mass comes to within 0.5 cm of the deep. per/outer quadrant and lower/outer quadrant fibrous tissue. mass is markedly dense and nodular. Located in the. u. =1,. quan ant, adjacent to the superior-medial portion of mass #1,. is a secu fairly well defined mass measuring 0.9 x 0.8 x 0.5 cm. This. mass is located 2.0 cm from the deep margin. The second mass is located. approximately 1.5 cm from the first mass. The remainder of the specimen. is. composed of lobulated, yellow-tan adipose tissue admixed with a moderate. amount of otherwise unremarkable fibrous tissue. Located along the. lateral edge of the specimen (at the junction of the deep and superficial. margins) there is a single 0.4 cm ill-defined induration. This lateral. margin is inked blue. No lymph nodes are identified. Representative. sections are submitted as follows: C1 - skin; C2- upper/outer quadrant. mass; C3- upper/outer quadrant deep margin (to C2) ; C4- outer mid (OM). mass with cavity and deep margin; C5- deep margin, OM; C6- outer mid mass. C7-C9- additional outer mid mass; C10-C11- - induration along margin; C12-. upper/inner quadrant; C13- lower/inner quadrant; C14-lower/outer quadrant;. C15-upper/outer quadrant; C16- nipple; C17- sections of firm areas between. first and second mass. Matched sections of C1,C2,C4,C6-C9 and C12-C15 are submitted in OCT and. Specimen #: GROSS DESCRIPTION (continued) : Paraffin per CBCP protocol. D: Received in formalin, labeled with the patient's name. d designated, "New Inferior Margin" consists of an unoriented. The specimen is inked. Serial sectioning reveals a yellow lobular cut. fragment. of yellow lobular adipose tissue measuring 14.0 x 6.5 x 3.0 cm. surface with no well defined lesions or nodules grossly identified and. scattered areas of dense fibrous tissue. Representative sections are. submitted in seguential order in six cassettes representing various. fibrous areas. Time in formalin: >80 hours.

expanded version (tokens=2344) : 
 Histological classification: 
- invasive lobular carcinoma (ILC)
- lobular carcinoma in situ (LCIS)

Subtype:
- Luminal A

Description of necrosis: 
- Not identified in the ILC. 
- Not mentioned for the axillary tissue.

Tumor infiltrating lymphocytes: 
- Mentioned in slide C6: presence of lymphovascular invasion.

Histological grade: 
- ILC: Grade 2, moderately differentiated; Nottingham score of 6. 
- LCIS: not applicable.

Nuclear grade: 
- ILC: not mentioned. 
- LCIS: not applicable.

Lymphovascular invasion: 
- Present in slide C6.

Calcification: 
- Microcalcifications are present and associated with the invasive and in situ tumor, as well as with non-neoplastic tissue.

Receptor status: 
- Estrogen receptors are positive. 
- Progesterone receptors are positive. 
- HER2 neu by IHC is negative. 

Ancillary testing results:
- Cytokeratin immunohistochemical staining was performed on the sentinel lymph node #1 to detect isolated tumor cells (ITC). 

Other findings: 
- Multifocality of the tumor in the breast.
- Negative margins.
- One out of two examined sentinel lymph nodes had isolated tumor cells.
- No extranodal extension or involvement of the nipple/skin identified.
- Prior biopsy site cavity/changes present.
-

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2479) : 
 Final Diagnosis: LumA ILC & LCIS with lymphovascular invasion present. Grade 2, Nottingham score 6. Positive estrogen and progesterone receptors, negative HER2 neu by IHC. Multifocal tumor with microcalcifications. Negative margins and no involvement of nipple/skin or extranodal extension identified.
One out of two sentinel lymph nodes contained isolated tumor cells. Prior biopsy site cavity/changes present.

