prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - SPECIMEN. A. Right axillary sentinel node. B. Right breast silk stitch marks superior breast. CLINICAL NOTES. PRE-OP DIAGNOSIS: Right breast cancer. CLINICAL HISTORY: year old female with breast cancer. POST-OP DIAGNOSIS: Right breast cancer. FROZEN SECTION DIAGNOSIS. A. Right axillary sentinel node, biopsy: Three lymph nodes. Negative for malignancy on frozen. GROSS DESCRIPTION. The specimen is received fresh for frozen section labeled. "A. right axillary sentinel node" and consists of a 5.5 x. 3. x 1.5 cm. piece of fatty yellow tissue. The specimen is sectioned to. reveal three separate lymph nodes. One measures 4 cm. in greatest. dimension and shows prominent fatty replacement of the hilus. Another node measures 1.5 cm. in greatest dimension and the smallest. lymph node appears to measure 1 cm. in greatest dimension. The lymph. node tissue is entirely frozen. The largest lymph node is sectioned. and entirely frozen as frozen sections AFS1 and AFS2. The medium. sized lymph node is entirely frozen as frozen section AFS3 and the. possible smallest lymph node is frozen as frozen section AFS4. RS4. kaa. B. Received fresh for tissue procurement labeled "right ). breast" is a 24.5 cm. (superior to inferior) x 19.0. cm. (medial to lateral) x 5.0 cm. (anterior to posterior) diffusely. cauterized soft, lobulated tan gold-white portion of fibroadipose. tissue in keeping with breast designated as right per requisition. slip and container and oriented by a single suture as stated. previously. There is a 7.5 cm. (medial to lateral) x 4.5 cm. (superior to inferior) slightly wrinkled white skin ellipse with. a. central, inverted, 0.5 x 0.5 cm. nipple along the anterior aspect. The intact deep margin is inked black and the specimen is sectioned. There is a stellate, 2.2 cm. (medial to lateral) x 1.6 cm. (superior. to inferior) x 1.3 cm. (anterior to posterior) tan white lesion at. the junction of the four quadrants subjacent to the aforementioned. skin ellipse. The lesion is 4.0 cm. from the inked deep margin and. 1.7 cm. from the overlying skin ellipse. A 2.3 cm. (anterior to. posterior) x 1.3 cm. (superior to inferior) x 1.3 cm. (medial to. lateral) vacant biopsy cavity is present medial to the. aforementioned lesion. A portion of the lesion and a portion of. normal parenchyma are submitted for tissue procurement as requested. The cut surfaces throughout the remainder of the specimen consist. predominantly of glistening lobulated golden yellow adipose tissue. with a minimal amount of interspersed delicate tan-white fibrous. tissue. A single, 0.3 cm. "blue dome cyst" is identified within the. lower outer quadrant (see block 10). Representative sections are. submitted in 11 blocks as labeled. RS-11. BLOCK SUMMARY: 1 - Deep margin subjacent to lesion; 2 - lesion to. overlying skin ellipse; 3-6 - lesion and representative biopsy. cavity; 7 - random upper outer quadrant; 8 - upper inner quadrant;. 9. - lower inner quadrant; 10 - lower outer quadrant; 11 - nipple with. subjacent tumor. MICROSCOPIC DESCRIPTION. A. Microscopic examination of the sentinel lymph nodes. from the right axilla involve evaluation of two H&E-stained. sections at the time of frozen section and an additional three. i&E-stained sections of each of the tissue blocks after formalin. fixation and paraffin embedding. Pancytokeratin AE1/AE3. immunohistochemical stains were also evaluated. Although no tumor. was identified on the original frozen sections, tumor was identified. in the permanent sections in the largest lymph node in blocks AFS1. and AFS2. Overall, the metastatic tumor measures 8 mm in greatest. dimension. No extranodal tumor is identified (pNla). B. Microscopic examination of the right breast mastectomy. reveals. Invasive carcinoma: Present. Histologic type: Infiltrating lobular carcinoma. Histologic grade: Elston SBR grade 2. Overall grade: 2. Architectural score: 3. Nuclear score: 1-2. Mitotic score: 1. Greatest dimension (pT) : 2.2 cm (pT2). Specimen margins: Completely negative for tumor (much greater. than 1 cm from tumor). Vessel invasion: Not identified. Calcification Focally present. Nipple (Paget's) : There is no evidence of Paget's disease. Invasion of skin or chest wall: Not identified. Ductal carcinoma in situ: Not identified. Description of non-tumorous breast: Prominent lobular carcinoma in. situ was. identified associated with the invasive tumor and towards the edge. around the invasive tumor. The background tissue shows. proliferative fibrocystic. changes with florid ordinary ductal hyperplasia and columnar cell. change,. cysts and microcysts, apocrine metaplasia and sclerosing. adenosis. Comments: E-cadherin immunohistochemical stain was evaluated on. block 11 and demonstrated a lack of staining in both the invasive. and the in situ tumor,. helping to support the lobular interpretation. Distant metastasis (pM) : Cannot evaluate pMx. Prognostic markers: Have been ordered on block B11. Breast Prognostic Marker Report: % positive. Staining intensity. Estrogen receptor: 80%. Moderate- - strong. Progesterone receptor: 30%. Moderate. Her2/neu by IHC: Interpretation. Estrogen receptor: POSITIVE. Progesterone receptor: POSITIVE. Her2/neu by IHC: EQUIVOCAL, BLOCK B11 SENT FOR FISH. Comments. Fixation time: 30MIN. Cold ischemia time: 62HRS. Prognostic markers were done by immunohistochemical stain on. paraffin sections from 10% neutral buffered formalin fixed tissue. using Ventana corporation antibodies on a Benchmark automated. stainer. The Her2/neu antibody is clone 4B5 and has been approved by the. FDA as an aid in the assessment of breast cancer patients for whom. Herceptin treatment is considered. This laboratory meets the test validation and quality assurance. requirements of the ASCO/CAP guidelines for Her2 and ER testing for. carcinoma of the breast (Arch Pathol Lab Med 2007;131:18-43. Arch. Pathol Lab Med 2010; :907-922). ER,1 and HER-2 results are. scored using the recommended ASCO/CAP criteria. 4x2, 14x1, 15x3, 20x2, 25x3. DIAGNOSIS. A. Right axillary sentinel lymph nodes, biopsy: METASTATIC LOBULAR CARCINOMA PRESENT IN 1 OF 3 LYMPH NODES. Tumor 8 mm in greatest dimension, no extranodal tumor present. (pN1a). B. Right breast, mastectomy: Infiltrating lobular carcinoma, tumor size 2.2 cm in greatest. dimension (pT2). Resection margins are negative for invasive carcinoma. Lobular carcinoma in situ. Proliferative fibrocystic changes and prior biopsy site. effects. Estrogen receptor Positive. Progesterone receptor Positive. HER-2 Equivocal, block sent for FISH testing. See microscopic description. DIAGNOSIS. M.D. (Electronic Signature).

expanded version (tokens=2114) : 
 Histological classification: The pathology report reveals the presence of infiltrating lobular carcinoma in the right breast, and metastatic lobular carcinoma present in 1 out of 3 lymph nodes examined in the right axillary sentinel node biopsy.

Subtype: The type of cancer identified is infiltrating lobular carcinoma.

Description of any necrosis: There is no mention of necrosis.

Tumor infiltrating lymphocytes: There is no mention of tumor infiltrating lymphocytes.

Histological grade: The histologic grade of the invasive carcinoma is Elston SBR grade 2, with overall grade 2, architectural score 3, nuclear score 1-2, and mitotic score 1.

Nuclear grade: The nuclear grade is 1-2.

Lymphovascular invasion: There is no mention of lymphovascular invasion.

Calcification: Calcification is focally present.

Receptor status: The tumor is estrogen receptor positive and progesterone receptor positive.

IHC and ancillary testing results: The HER-2/neu by IHC is equivocal and has been sent for FISH testing. E-cadherin immunohistochemical stain shows a lack of staining in both the invasive and in situ tumors, supporting the lobular interpretation. Prognostic markers were done by immunohistochemical stain on paraffin sections using Ventana corporation antibodies, and the laboratory meets the test validation and quality assurance requirements of the ASCO/CAP guidelines for HER-

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2284) : 
 The pathology report reveals infiltrating lobular carcinoma in the right breast and metastatic lobular carcinoma in one of three lymph nodes examined. The tumor is histologically graded as Elston SBR grade 2 with overall grade 2, nuclear grade 1-2, and mitotic score 1. Calcification is focally present. The tumor is estrogen receptor positive and progesterone receptor positive, while HER-2/neu result is equivocal and has been sent for FISH testing. E-Cadherin shows lack of staining in both invasive and in situ tumors supporting the lobular interpretation.

