prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Final Surgical Pathology Report. Procedure: Diagnosis. A. Right axillary sentinel node, excisional biopsy: Single lymph node negative for metastatic tumor (0/1). B. Breast, right, simple mastectomy: Invasive lobular carcinoma, grade 1. Tumor size 7.5 CM (pT3). Resection margin negative for tumor. Microscopic Description: A. and B. Microscopic examination performed. Invasive carcinoma: Histologic type: Invasive lobular carcinoma. Histologic grade: 1. Overall grade. Architectural score: 3. Nuclear score: 1. Mitotic score: 1. Greatest dimension (pT) 7.5 CM (pT3). Specimen margins: Negative for malignancy, deep margin is 1.4 cm. from tumor. Vessel invasion: Not identified. Calcification: Focally present. Nipple (Paget's ) : Unremarkable, no Paget's disease identified. Invasion of skin or chest wall: Not identified. Ductal carcinoma in situ: No ductal carcinoma in situ identified. Description of non-tumorous breast: Fatty and atrophic. Adjacent to. the tumor are too small 1 cm fibroadenomas which are invaded by the. tumor. Lymph nodes: Number of positive nodes of total: 0/1. Extracapsular extension (present/absent) : No extracapsular tumor. identified. pN: snpNO. 2 H&E-stained sections were evaluated from each frozen section block. An additional 3 H&E stained sections from each tissue block were. evaluated of the formalin fixed paraffin embedded tissue. Also. pancytokeratin AE1/AE3 immunohistochemical stains were evaluated from. each of the tissue blocks. No metastatic tumor was identified in any. of these examined sections. [A few of the antibodies used in our laboratory may be classified as. analyte specific reagents. These antibodies are monitored and. controlled in our laboratory and their performance for in vitro. diagnosis is well described in the medical literature. They have not. been cleared or approved by the FDA.]. Distant metastasis (pM) : Not applicable pMX. Breast prognostic marker results (B5) Progesterone and HER-2 testing. was repeated given the limited amount of tumor in the prior core. biopsy. Progesterone receptor: 0%. Her2 by IHC: 2+. Interpretation receptor: Reported as positive on prior core biopsy. Estrogen. Her2 by IHC: Equivocal by IHC. FISH testing ordered. Progesterone receptor: Negative. Comments. Fixation time: 28 hours. Cold ischemia time Time of collection was not noted. Less than. 15 minutes cold ischemia time in the laboratory. Favor less than 1. hour of transport time. The analyzed tissue met quality requirements of the. CAP guidelines. for Her2 testing. Control materials stained appropriately. Based on data collected in our laboratory and reported in the. literature we recommend FISH analysis for Her2 in cases that stain with. intermediate intensity by immunohistochemistry. sections from 10% neutral buffered formalin fixed tissue using. Prognostic markers were done by immunohistochemical stain on paraffin Ventana. corportation antibodies on a Benchmark automated stainer. The Her2 antibody is clone 4B5 and has been approved by the FDA as an. aid in the assessment of breast cancer patients for whom Herceptin. treatment is considered. This laboratory meets the test validation and quality assurance. requirements of the. /CAP guidelines for Her2, ER and PR testing for. carcinoma of the breast. A. Specimen Right axillary sentinel lymph node, excisional biopsy: B. Right breast, simple mastectomy. Clinical Information. year-old white female with infiltrating lobular carcinoma. Intraoperative Consultation. A. Right axillary sentinel node, biopsy: No tumor seen. Gross Description. A. Received fresh for frozen section labeled "right axillary sentinel. is a 3 x 1 x 1 CM piece of fatty yellow tissue. The fat is. node" trimmed to reveal a 2.8 cm diameter tan lymph node. The lymph node is. bisected and entirely frozen as frozen sections AFS 1 AFS 2. The fat. is retained. No blue staining was identified and no grossly suspicious. areas are identified. B. Received fresh and subsequently fixed in formalin labeled "right. breast" is a 20.5 x 17.2 x 4.7 cm yellow lobular fatty tissue fragment with. 7.5 x 3.5 cm pink-tan wrinkled skin ellipse having a 1.4 cm everted. is grossly consistent with a mastectomy and is partially covered a. nipple. The specimen has a suture designating superior breast. The. specimen is received in pathology at. and fixed in formalin at. The deep aspect of the specimen is inked lumen and the. specimen is sectioned from medial to lateral to show a 7.5 x 6.0 x 2.3. cm white-tan, diffusely nodular and firm central mass is ill. circumscribed and comes within 1.7 cm of the deep margin. Gross. identified centrally are white rice-like pellets which are grossly. consistent with a previous biopsy site. The remainder of the cut. surface of the specimen is predominantly fatty scanty fibrous tissue. present. No lymph nodes or gross identified in the apex of the. specimen. Representative sections of the specimen are submitted as. follows: 1 - entire nipple with representative skin, 2 - 6 -. representative sections of lesion including tumor to deep margin and. possible biopsy site, 7 - representative upper outer quadrant, 8 -. representative lower outer quadrant, 9 - representative lower inner. quadrant, 10 - representative upper inner quadrant. Discrepancy. /.

expanded version (tokens=1662) : 
 According to the Final Surgical Pathology Report, the following information can be extracted regarding breast pathology:

1. Histological classification: Invasive lobular carcinoma, grade 1.
2. Tumor size: 7.5 CM (pT3).
3. Resection margin: Negative for malignancy, deep margin is 1.4 cm from the tumor.
4. Necrosis: Not identified.
5. Tumor infiltrating lymphocytes: Not identified.
6. Histological grade: Grade 1. 
7. Nuclear grade: 1.
8. Lymphovascular invasion: Not identified.
9. Calcification: Focally present.
10. Receptor status and IHC: 
   - Progesterone receptor: 0% (negative).
   - HER-2 by IHC: 2+ (equivocal). FISH testing ordered.
   - Estrogen receptor: Reported as positive on prior core biopsy.
11. Additional ancillary testing: Pancytokeratin AE1/AE3 immunohistochemical stains were evaluated but no metastatic tumor was identified.
12. Distant metastasis: Not applicable pMX.
13. Lymph nodes: 0/1 positive for metastatic tumor (sentinel node).
14. Adjacent to the tumor are too small 1 cm fibroadenomas which are invaded by the tumor.

The report also includes information about the clinical information, intraoperative consultation, and gross description of the

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1819) : 
 The surgical pathology report reveals a 7.5 cm pT3 grade 1 invasive lobular carcinoma identified in a simple mastectomy of the right breast with negative margins and no lymphovascular invasion. Sentinel lymph node biopsy shows no metastatic tumor. Focally present breast calcifications and invaded adjacent small fibroadenomas are seen. The estrogen receptor reported as positive on the prior core biopsy while progesterone receptor is negative. The HER-2 status is equivocal by IHC, and hence, FISH testing was ordered.

