prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Gender: F. Provider Group : Date of Service: Date Received: FINAL SURGICAL PATHOLOGY REPORT. Diagnosis: A. - B.) LEFT BREAST AND AXILLARY LYMPH NODE, LUMPECTOMY AND SENTINEL. LYMPH NODE BIOPSY: - Invasive ductal carcinoma, Nottingham grade 3. - Tumor size: 6.8 cm in diameter. - Ductal carcinoma in situ (DCIS), high nuclear grade, with comedo necrosis. - DCIS is extensive, involving an area larger than the area involved by. invasive carcinoma. - The inferior lumpectomy margin is involved by DCIS (see comment for. additional information concerning margins). - Two lymph nodes, no tumor present (0/2). PATHOLOGY TUMOR STAGING SYNOPSIS: Type and grade (invasive): Invasive ductal carcinoma, Nottingham grade 3. Type and grade (in situ): DCIS, high nuclear grade. Primary tumor: pT3. Regional lymph nodes: pNO(i-)(sn). Distant metastasis: Not applicable. Stage: IIB. Lymphovascular invasion: Not identified. Margin status: Margin involved by carcinoma. See comment. COMMENT: The invasive carcinoma has an irregular, elongated multilobulated. configuration, with possible small satellite tumor nodules at the periphery of the. tumor. In some areas, the gross appearance of the tumor was subtle, and in other. areas where invasive carcinoma was present, no grossly demonstrable tumor could. be seen. The tumor size of 6.8 cm in diameter is based on the distribution of invasive. tumor in the specimen. DCIS is extensively present in association with invasive. carcinoma. The inferior margin is involved by DCIS, in both the medial and lateral aspects of the. specimen. In addition, DCIS is identified 0,1 cm from the anterior and superior. Printed: This report continues (FINAL). Acct No. >atient Name. Pathology - Page 1/5. age 1 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. margins. Carcinoma is identified 0.5 cm from the lateral and medial margins. Invasive. carcinoma is not identified at any margin, but is identified 0.2 cm from the anterior. and superior margins. In some areas, the invasive carcinoma has features suggestive of neuroendocrine. differentiation (nuclear molding, relatively scant cytoplasm, inconspicuous nucleoli),. and this impression is supported by positive staining for synaptophysin in tumor. cells. Intradepartmental consultation. has reviewed representative slides,. and concurs with the above diagnosis. Invasive Breast Cancer Tumor Staging Information. AJCC Cancer Staging Handbook, 7th Ed., and CAP Protocol (revised June 2012). Previous pathology specimens: : Printed: This report continues (FINAL). MR No. -. Acct No. Pathology - Page 2/5. Job. Page 2 Doc# 1. SPECIMEN IDENTIFICATION. Procedure/specimen type: Lumpectomy. Laterality: Left. Lymph node sampling: Sentinel lymph node biopsy. INVASIVE CARCINOMA TUMOR CHARACTERISTICS. Histologic type: Invasive ductal carcinoma (with neuroendocrine. differentiation). Tumor site: 1:00 aspect. Tumor size: 6,8 cm in diameter. Tumor focality: Single tumor focus (multilobulated) irregularly. shaped tumor with possible satellite nodules at. the periphery of the tumor). Histologic grade (Nottingham Score): 3 of 3. Tubule formation: 3 of 3. Nuclear pleomorphism: 3 of 3. Mitotic rate: 3 of 3. Lymphovascular invasion: Not identified. Macroscopic and microscopic extent of tumor: Skin and chest wall invasion cannot be. assessed. DUCTAL CARCINOMA IN SITU (DCIS): Present, extensive, nuclear grade 3. MARGINS. Invasive carcinoma: Invasive carcinoma is 0.2 cm from anterior and. superior margins, 0.5 cm from medial margin,. and is at least 0.5 cm from all other margins. Ductal carcinoma in situ: Present at inferior margin, 0.1 cm from anterior. and superior margins, 0.5 cm from lateral. margin, at least 0.5 cm from medial margin. LYMPH NODES. Total lymph nodes examined. Two. Number of lymph nodes involved. Zero. PATHOLOGIC STAGING. Primary Tumor (pT): pT3. Regional lymph nodes (pN): pNO(i-)(sn). Distant metastasis (pM): Not applicable. AJCC Stage: IIB. ANCILLARY STUDIES: Estrogen receptor: 95% positive cells. Printed: This report continues (FINAL). MR N. Pathology - Page 3/5. JOD. Page 3 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. Progesterone receptor: 60% positive cells. HER2: IHC 0. Ki-67: 25% positive cells. Source of Specimen: A. Sentinel lymph node;Left axillary (. B. Breast lumpectomy;Lef. Clinical History/Operative Dx: Matignant neoplasm of breast (female) unspecified site. Gross Description: A, Part A is. sentinel node #1, left axillary. Received in formalin is a 2.4 x 1.8x 1.8 cm portion of. fatty soft tissue. Examination reveals a lymph node, 1.6 x 1.0 x 0.7 cm. The lymph node is serially. sectioned and entirely submitted for microscopic evaluation in A1 with a sentinel node protocol. performed. A second lymph node is 0.4 x 0.3 x 0.2 cm. This lymph node is bisected and submitted in A2. Routine histology and sentinel node protocol is performed on blocks A1 and A2,. B. Part B is left breast mass. Initially received in the fresh state for possible Oncogenotyping studies is a. 178 gram yellow-tan portion of fibrofatty soft tissue, 9.3 cm superior-inferior, 9.3 cm medial-lateral, and. 4 8 cm posterior-anterior An overlying ellipse of wrinkled. tan skin is 7.5 1.1 cm. Two sets of sutures are. present: a double long suture marks lateral and a double short suture marks superior. The surgical margins. are now differentially inked as follows: SUPERIOR: BLUE. MEDIAL: RED. ANTERIOR: YELLOW. Printed: This report continues. Acct No. . Pathology - Page 4/5. Jop. Page 4 Doc# 1. FINAL SURGICAL PATHOLOGY REPORT. INFERIOR: GREEN. LATERAL: ORANGE. POSTERIOR: BLACK. The specimen is sliced from medial to lateral in seven slices, with slice #1 most medial, slice #7 most. lateral. There is an irregularly shaped elongated mass measuring 6.8 x 3.5 x 2.4 cm (present in slices. #1-6). The tumor is 0.7 cm from the medial, 1.8 from the lateral, 0.6 cm from the anterior, 1.9 cm from the. posterior, 0.4 cm from the superior (slab 3) and 1.8 cm from the inferior surgical margins. Representative. tissue submitted for Oncogenotyping studies. A second partially calcified, light gray fibrous nodule is 1.1 X 0.7 x 0.6 cm, located along the inferior. aspect in slice #2. Cassette summary: B1-B3) slab 1, medial including tumor relationship,. B4-B7) slab 2, including superior, inferior, medial-posterior. anterior and tumor relationship,. B8) fibrous-calcified nodule, along inferior margin, slab 2, over-night decal performed,. B9-B14) slab 3, inferior, superior, anterior, posterior surgical margins including tumor relationship,. B15-B20) slab 4, anterior, superior, inferior, posterior surgical margins and tumor relationship,. 821-B25) slab 5. inferior, posterior, anterior, superior surgical margins and tumor relationship, and. representation of bulk of tumor,. B26-B30) slab 6, inferior, anterior, posterior, and superior surgical margins, area suspicious for tumor,. B31-B35) slab 7, lateral, edge of inferior margin represented. Microscopic Description: A, immunohistochemical stain: CK-OSCAR, showing no evidence of metastatic carcinoma. Appropriate. positive and negative controls reviewed. 8. Immunohistochemica stain: synaptophysin, showing positive staining in tumor cells, Appropriate. positive and negative controls reviewed. Printed: END OF REPORT (FINAL). MR No. -. Acct No. tient Name -. Pathology - Page 5/5. 'age 5 Doc# 1.

expanded version (tokens=2357) : 
 Histological classification:
- Invasive ductal carcinoma, Nottingham grade 3
- Ductal carcinoma in situ (DCIS), high nuclear grade, with comedo necrosis
- LumA subtype

Subtype:
- LumA subtype

Necrosis:
- Comedo necrosis identified in DCIS

Tumor infiltrating lymphocytes:
- No mention of tumor infiltrating lymphocytes

Histological grade:
- Nottingham grade 3
- High nuclear grade DCIS

Nuclear grade:
- High nuclear grade DCIS

Lymphovascular invasion:
- Not identified

Calcification:
- Partially calcified, light gray fibrous nodule located along the inferior aspect in slice #2

Receptor status:
- Estrogen receptor: 95% positive cells
- Progesterone receptor: 60% positive cells
- HER2: IHC 0
- Ki-67: 25% positive cells

Ancillary testing results:
- Positive staining for synaptophysin in tumor cells
- CK-OSCAR immunohistochemical stain showing no evidence of metastatic carcinoma

Margin status:
- Invasive carcinoma is identified 0.2 cm from anterior and superior margins, 0.5 cm from medial margin, and is at least 0.5 cm from all other margins.
- DCIS is present at inferior margin, 0.1 cm from anterior and superior margins, 0.5 cm from lateral margin, and

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2526) : 
 The pathology report shows invasive ductal carcinoma, Nottingham grade 3, with high nuclear grade DCIS. The subtype is LumA. No tumor infiltrating lymphocytes were mentioned, and no lymphovascular invasion was identified. Partially calcified fibrous nodule was seen along the inferior margin in slice #2. Estrogen receptor (ER) status was 95% positive cells, progesterone receptor (PR) was 60%, HER2 IHC staining showed 0, and Ki-67 was 25%. The invasive carcinoma involved margins, whereas the DCIS involved the inferior margin.

