prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Clinical Diagnosis & History: year old female with 2.7 cm right breast cancer, lower outer quadrant and. FNA (+) metastatic right lymph node. Specimens Submitted: 1: SP: Right breast and axillary contents levels one and two with tags. attached. 2: SP: Subscapular nodes, right axilla level one. DIAGNOSIS: 1. BREAST, RIGHT; MASTECTOMY AND AXILLARY DISSECTION: - INVASIVE DUCTAL CARCINOMA, MIXED MUCINOUS & NOS TYPE AND WITH. SOLID-PAPILLARY FEATURES, HISTOLOGIC GRADE III/III (SLIGHT OR NO TUBULE. FORMATION), NUCLEAR GRADE II/III (MODERATE VARIATION IN SIZE AND SHAPE). MEASURING 2.3 CM IN LARGEST DIMENSION MICROSCOPICALLY. - (DCIS) IS ALSO IDENTIFIED, SOLID AND CRIBRIFORM TYPES WITH. INTERMEDIATE NUCLEAR GRADE. AND MINIMAL NECROSIS. - LOBULAR INVOLVEMENT BY DCIS IS PRESENT. - THE DCIS CONSTITUTES LESS THAN OR EQUAL TO 25% OF THE TOTAL TUMOR. MASS, AND IS PRESENT. ADMIXED WITH AND AWAY FROM THE INVASIVE COMPONENT. - THE INVASIVE CARCINOMA IS LOCATED IN THE LOWER OUTER QUADRANT. - THE DCIS IS LOCATED IN THE LOWER OUTER QUADRANT AND LOWER INNER. QUADRANT. - NO INVOLVEMENT OF THE NIPPLE BY EITHER IN SITU OR INVASIVE CARCINOMA. IS IDENTIFIED. - CALCIFICATIONS ARE PRESENT IN BENIGN BREAST PARENCHYMA. - VASCULAR INVASION IS PRESENT. - INVASIVE CARCINOMA IS CLOSE (LESS THAN OR EQUAL TO 1 MM) TO THE. FOLLOWING SURGICAL. MARGIN(S) : BLUE INKED MARGIN (ANTERIOR). NO SKIN INVOLVEMENT BY CARCINOMA IS IDENTIFIED. - THE NON-NEOPLASTIC BREAST TISSUE SHOWS BIOPSY SITE CHANGES AND. PROLIFERATIVE FIBROCYSTIC. CHANGES INCLUDING INTRADUCTAL PAPILLOMA. - LEVEL 1: METASTATIC ADENOCARCINOMA TO FOUR OUT OF TEN LYMPH NODES. (4/10). THE LARGEST METASTATIC FOCUS MEASURES 2.5 CM. THERE IS EXTRANODAL EXTENSION OF CARCINOMA, FOCAL. - LEVEL 2 : THREE BENIGN LYMPH NODES (0/3). Page or. IMMUNOHISTOCHEMICAL STAIN WAS PERFORMED ON FORMALIN-FIXED TISSUE WITH THE. FOLLOWING RESULTS FOR INVASIVE CARCINOMA (BLOCK 1T6) : HER2. NEGATIVE (0 / 1+). 5% OF INVASIVE TUMOR CELLS EXHIBIT COMPLETE MEMBRANOUS STAINING;. UNIFORMITY OF STAINING: ABSENT. HOMOGENEOUS, DARK CIRCUMFERENTIAL PATTERN: ABSENT. Comment: Controls are satisfactory. s PATHWAY anti-HER-2/neu is an. FDA-approved rabbit monoclonal primary antibody (clone 4B5) directed against. the internal domain of the c-erbB-2 oncoprotein (HER2) for. immunohistochemical detection of HER2 protein overexpression in breast. cancer tissue routinely processed for histologic evaluation. The HER2 test. results are reported in accordance with the ASCO/CAP guideline. recommendations for HER2 testing in breast cancer (J Clin Oncol 2007;. 25 (1) :118-145) The ER and PR rabbit monoclonal antibodies are also FDA. approved. 2. LYMPH NODES, RIGHT AXILLA LEVEL ONE, SUBCAPSULAR: - SIX BENIGN LYMPH NODES (0/6). Some of the immunohistochemistry and. tests were develoned and their. performance characteristics were determined by. They have not been cleared or approved by the US Food and Drug. Administration. The FDA has determined that such clearance or approval is. not necessary. These tests are used for clinical purposes. They should not. be regarded as investigational or for research. This laboratory is certified. under the Clinical Laboratory Improvement Amendments of 1988 (CLIA , 88) as. qualified to perform high complexity clinical laboratory testing. I ATTEST THAT THE ABOVE DIAGNOSIS IS BASED UPON MY PERSONAL EXAMINATION OF. THE SLIDES (AND/OR OTHER MATERIAL) AND THAT I HAVE REVIEWED AND APPROVED. THIS REPORT. Gross Description: 1) The specimen is received fresh labeled, "right breast and axillary. contents levels one and two with tags attached and consists of a breast. measuring 19 x 18 x 3 cm with overlying skin ellipse measuring 11 x 3 cm. Situated centrally on the skin surface is an everted nipple measuring 1 x 1. x 0.6 cm and areola measuring 3 x 3 cm. A suture demarcates the axillary. contents which measures 11 x 7 x 3 cm. Two tags are present, designating. levels one and two. The posterior surface of the breast is inked black, the. anterior blue and the axillary aspect is inked yellow. The specimen is. serially sectioned to reveal a 2.5 cm diameter mass in the lower outer. Page 3 or. quadrant and 1 cm from the deep margin. A clip is identified in the mass. The remaining breast tissue shows nodular fibroadipose tissue. The axillary. tisbue is dissected to reveal multiple lymph nodes, ranging in size from 0.5. cm to 2.5 cm. Representative sections are submitted. All dissected lymph. nodes are entirely submitted. Summary of sections: N - nipple. NB - nipple base. D - deep margin. T - tumor. UIQ - upper inner quadrant. LIQ - lower inner quadrant. UOQ - upper outer quadrant. LOQ - lower outer quadrant. L1 lymph nodes, level 1. L2 lymph nodes level2. 2). The specimen is received in formalin, labeled "subscapular nodes right. axilla level one" and consists of pink tan firm lymph nodes ranging from 0.8. to up 2 cm in greatest dimension. All identified lymph nodes are submitted. Summary of sections: LN lymph nodes. BLN- bisected lymph nodes. Summary of Sections: Part 1: SP: Right breast and axillary contents levels one and two with tags. attached. Block. Sect. Site. PCs. 1. D. 1. 6. L1. 6. 1. L2. 2. 1. LIQ. 1. 1. LOQ. 1. 2. N. 2. 1. NB. 1. 3. 3. 1. UIQ. 1. 1. UOQ. 1. Part 2: SP: Subscapular nodes, right axilla level one. Block. Sect. Site. PCs. 2. BLN. 2. 1. LN. 1. Page 4 or.

expanded version (tokens=2011) : 
 Histological classification: Invasive ductal carcinoma, mixed mucinous & NOS type and with solid-papillary features, histologic grade III/III (slight or no tubule formation), nuclear grade II/III (moderate variation in size and shape); DCIS of solid and cribriform types with intermediate nuclear grade and minimal necrosis; lobular involvement present.

Subtype: LumA.

Tumor infiltrating lymphocytes: No mention of TILs.

Histological grade: Histologic grade III/III.

Nuclear grade: Nuclear grade II/III.

Necrosis: Minimal necrosis identified in DCIS.

Lymphovascular invasion: Vascular invasion is present.

Calcification: Calcifications are present in benign breast parenchyma.

Receptor Status: HER2 negative (0/1+), ER and PR results not mentioned.

Ancillary Testing results: No additional ancillary testing results mentioned.

Overall, the report indicates the presence of invasive ductal carcinoma with mixed mucinous and NOS type and solid-papillary features, along with DCIS of solid and cribriform types. The tumor has a histologic and nuclear grade of III/III and II/III, respectively, and shows evidence of vascular invasion. The report does not provide information on receptor status for ER and PR, but notes that the tumor is HER2 negative. Calcifications were present in benign breast parenchyma, and no additional ancillary testing results were

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2148) : 
 The pathology report indicates the presence of invasive ductal carcinoma with mixed mucinous and NOS type and solid-papillary features along with DCIS of solid and cribriform types. Tumor is HER2 negative, has a histologic grade III/III, nuclear grade II/III, and shows evidence of vascular invasion. Lobular involvement present, calcifications also seen in benign breast parenchyma. Further tests are not mentioned.

