prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, CLINICAL HISTORY: Left breast Ca. Left breast mass. GROSS EXAMINATION: A. "Left breast mass (AF1)". received fresh for frozen section. A 7.3 x 4.4 x. 2.5 cm ovoid fragment of soft yellow fibroadipose which has been previously. sectioned revealing a 1.7 x approximately 1.6 x 1.4 cm firm stellate. circumscribed yellow-tar mass. The surgeon has stated the margins are not an. issue on this specimen the mastectomy is to be performed. A portion of the. lesion has been previously submitted as frozen section AF1. Fresh tissue for. ER/PR was not submitted. The remainder of the specimen composed of soft yellow. lobulated adipose tissue without additional focal lesions. BLOCK SUMMARY: A1- frozen section AF1 remnant. A2- additional section of mass. A3-A4- additional tissue in the area of lesion. A5- representative of the remainder fibroadipose tissue. B. "Left breast", received fresh and placed in formalin. A 701.6 gram, 35 x. 18.3 x 3.0 cm left breast and axillary dissection is received. The breast is. 21.1 x 18.3 x 3.0 cm in greatest dimension and the axilla is 7.5 x 6.5 x 1.5. cm in greatest dimension. The overlying ellipse of white skin is 19 x 8.2 cm. in greatest dimension. The nipple is located slightly inferior and medial on. the skin surface and is retracted and exhibits a crusted skin surface and is. approximately 1 cm in greatest diameter with a 3.5 cm areola. Superior to the. nipple is a 7.5 cm long recent linear suture surgical incision. The surgical. margin is marked with blue ink and the specimen is sectioned revealing a fresh. biopsy cavity, approximately 7.5 x 6.5 x 6 cm in greatest dimension lined by. soft hemorrhagic adipose tissue. The biopsy cavity is grossly within 0.5 cm. with closest deep surgical margin, 12.5 cm with the closest inferior soft. tissue surgical margin. The tumor does not grossly identified within the. specimen. The remainder of the breast tissue is composed of soft lobulated. fibroadipose tissue with only small amount of pink-tan fibrous breast tissue. BLOCK SUMMARY: B1- nipple. B2- representative through incision on skin surface. B3- biopsy cavity in closest deep margin. B4-B5- additional sections of biopsy cavity wall. B6- closest superior soft tissue margin. B7- - closest inferior soft tissue margin. B8- representative upper inner quadrant. B9- representative lower inner quadrant. B10-representative lower outer quadrant. B11- representative upper outer quadrant. The axillary dissection is removed from the mastectomy specimen, divided into. proximal, mid, and distal thirds and examined for lymph nodes. Several lymph. node candidates from 0.5 to 3.2 cm are identified, predominantly in the distal. third of the specimen. Lymph nodes are submitted as follows: B12- one lymph node candidate from proximal. B13- one bisected lymph node candidate from proximal. B14- one lymph node candidate from mid. B15- one bisected lymph node candidate from mid. 1 of 3. B16- five lymph node lymph node candidates from distal. B17- - three lymph node candidates from distal. B18- one bisected lymph node candidate from distal. B19- one bisected lymph node candidate from distal. B20- one bisected lymph node candidate. INTRA OPERATIVE CONSULTATION: A. "Left breast biopsy": AF1- infiltrating lobular carcinoma (Dr. DIAGNOSIS: A. "LEFT BREAST MASS" (EXCISIONAL BIOPSY) : INFILTRATING CARCINOMA, LOBULAR TYPE. GROSS TUMOR SIZE, 1.7 X 1.6 x 1.4 CM (GROSSLY). SIZE OF INVASIVE COMPONENT 1.7 CM. LYMPHATIC/VASCULAR INVASION: ABSENT. MULTIFOCAL TUMOR: NO. IN SITU CARCINOMA PRESENT, OCCUPYING LESS THAN 5% OF TUMOR (SLIDE A-2,. A-4). TYPE OF IN SITU CARCINOMA: LOBULAR TYPE. EXTENSIVE INTRADUCTAL COMPONENT: NO. STATUS OF NON-NEOPLASTIC BREAST TISSUE INCLUDES PROLIFERATIVE. FIBROCYSTIC CHANGES WITH ATYPIA, INTRADUCTAL PAPILLOMA (SLIDE A-3). MICROCALCIFICATION PRESENT IN ASSOCIATION WITH BENIGN BREAST TISSUE. SURGICAL MARGIN STATUS: (SEE COMMENT). ESTROGEN/PROGESTERONE RECEPTOR AND CELL CYCLE ANALYSIS PENDING. B. "LEFT BREAST WITH AXILLARY DISSECTION", (REMOVAL) : RESIDUAL INFILTRATING AND IN-SITU CARCINOMA: ABSENT. STATUS OF NON-NEOPLASTIC BREAST TISSUE: INTRADUCTAL PAPILLOMA, ATYPICAL. DUCTAL HYPERPLASIA. MICROCALCIFICATIONS PRESENT IN ASSOCIATION WITH ATYPICAL DUCTAL. HYPERPLASIA. NIPPLE STATUS: FREE OF TUMOR. SKIN STATUS: FREE OF TUMOR. MUSCLE STATUS: NOT SAMPLED. SURGICAL MARGIN STATUS: NEGATIVE. LYMPH NODE STATUS: NO EVIDENCE OF MALIGNANCY IN 16 LEFT AXILLARY LYMPH. NODES, (0/16) . COMMENT: The surgical margin of the biopsy specimen was not evaluated, as the. mastectomy was performed during the same procedure, per conversation with the. surgeon. The resection margins of the mastectomy specimen are negative for. tumor. I certify that I personally conducted the diagnostic evaluation of the above. specimen (s) and have rendered the above diagnosis (es) . ADDENDUM 1: Tissue was sent to the. for assay of the estrogen. and progesterone receptors. The estrogen receptor activity was judged to be. POSITIVE with an estimated FMOL value of 154. The progesterone receptor. activity was judged as POSITIVE with an estimated FMOL value of 106. Please. refer to. for a complete report. I certify that I personally conducted the diagnostic evaluation of the above. specimen (s) and have rendered the above diagnosis (es). 2 of 3.

expanded version (tokens=1860) : 
 Histological classification: 
- Left breast mass: infiltrating lobular carcinoma
- Left breast with axillary dissection: residual infiltrating and in-situ carcinoma

Subtype: LumA

Description of necrosis: Absent

Tumor infiltrating lymphocytes: Not mentioned

Histological grade: Not mentioned

Nuclear grade: Not mentioned

Lymphovascular invasion: Absent

Calcification: Present in association with benign breast tissue

Receptor status: Estrogen receptor activity was positive with FMOL value of 154; progesterone receptor activity was positive with an estimated FMOL value of 106

IHC and ancillary testing results: Cell cycle analysis is pending. Intraductal papilloma and atypical ductal hyperplasia were present in non-neoplastic breast tissue. Microcalcifications were also present in association with atypical ductal hyperplasia. 

Surgical margin status: The resection margins of the mastectomy specimen are negative for tumor. The surgical margin on the biopsy specimen was not evaluated. 

Overall, the report shows that the patient has left breast cancer with a subtype of LumA and infiltrating lobular carcinoma. There was no necrosis observed and no tumor infiltrating lymphocytes were mentioned. The tumor had positive estrogen and progesterone receptor activity. No mention of histological grade or nuclear grade was made. Lymphovascular invasion was absent, and microcalcifications were present. The surgical margin of the

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2026) : 
 The pathology report shows that the patient has left breast cancer with a subtype of LumA and infiltrating lobular carcinoma. No necrosis or tumor-infiltrating lymphocytes were present. The tumor was estrogen and progesterone receptor-positive. Lymphovascular invasion was absent, a microcalcification was found, and surgical margins on the mastectomy specimen were negative for tumor. Histological/nuclear grade was not mentioned, intraductal papilloma & atypical ductal hyperplasia were present in non-neoplastic tissue with an extensive intraductal component absent.

