prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumB, PATIENT HISTORY: The patient is a year-old female. Date of last menstrual period: Not given. PRE OP DIAGNOSIS: Ca left breast. POST OP DIAGNOSIS: Same. PROCEDURE: Sentinel node biopsy, total mastectomy. ADDENDA: Addendum. ESTROGEN/PROGESTERONE AND HER-2/NEU REPORT. Using appropriate positive and negative controls, the test for the presence of these hormone receptor proteins is. performed by the immunoperoxidase method, and reported according to the NIH consensus statement on adjuvant. therapy for breast cancer, of. A positive ER or PR tumor shows any nuclear immunostaining, and is. semiquantitated as indicated below. Semiquantitative Statement. ER positive. Percent cells staining as: (0 20%; 1+ 30%, 2+ 30%, 3+ 20%). PR positive. Percent cells staining as: (0 70%, 1+ 10%, 2+ 10%, 3+ 10%). HER-2/NEU DAKO HERCEPTEST: A STRONG COMPLETE MEMBRANE STAINING IS OBSERVED IN MORE THAN 10% OF. THE TUMOR CELLS. HER-2/NEU IS INTERPRETED AS STRONGLY POSITIVE (SCORE 3+). FINAL DIAGNOSIS: PART 1: LEFT BREAST, TOTAL MASTECTOMY -. A. INFILTRATING DUCT CARCINOMA, TWO LESIONS, 2.6 X 1.7 X 1.5 CM IN THE LOWER OUTER QUADRANT. AND 3.0 x 2.8 X 2.5 CM IN THE UPPER OUTER QUADRANT NOTTINGHAM SCORE 9 OUT OF 9 (TUBULES 3,. NUCLEI 3, MITOSIS 3). B. LYMPHOVASCULAR INVASION IDENTIFIED. C. DUCTAL CARCINOMA IN-SITU, SOLID TYPE, NUCLEAR GRADE 3 WITH COMEDO-TYPE NECROSIS,. COMPRISING LESS THAN 5% OF TUMOR. D. SURGICAL MARGINS NEGATIVE FOR INFILTRATING DUCT CARCINOMA AND DUCTAL CARCINOMA IN-. SITU. E. INFILTRATING DUCT CARCINOMA FOCALLY APPROACHES VERY CLOSELY MARGIN OF EXCISION IN. THE LOWER OUTER QUADRANT (WITHIN 0.2 CM). F. NIPPLE NEGATIVE FOR TUMOR. G. CHANGES CONSISTENT WITH PREVIOUS CORE BIOPSY SITE. H. TWO LYMPH NODES, POSITIVE FOR METASTATIC CARCINOMA (2 OUT OF 2). PART 2: LEFT BREAST, NEW ANTERIOR-INFERIOR MARGIN, EXCISION -. SKIN AND SUBCUTANEOUS TISSUE, NEGATIVE FOR TUMOR. PART 3: LEFT SENTINEL LYMPH NODE #1, BIOPSY -. ONE LYMPH NODE POSITIVE FOR METASTATIC CARCINOMA (1 OUT OF 1). PART 4: LEFT SENTINEL LYMPH NODE #2, BIOPSY -. ONE LYMPH NODE NEGATIVE FOR METASTATIC CARCINOMA (0 OUT OF 1). PART 5: LEFT SENTINEL LYMPH NODE #3, BIOPSY -. ONE LYMPH NODE POSITIVE FOR METASTATIC CARCINOMA (1 OUT OF 1). PART 6: LEFT AXILLARY CONTENTS, EXCISION -. FIVE OF ELEVEN LYMPH NODES POSITIVE FOR METASTATIC CARCINOMA, THREE WITH EXTRACAPSULAR. EXTENSION. PART 7: RIGHT BREAST TISSUE, EXCISION (396 GRAMS) -. A. FOCAL ATYPICAL DUCTAL HYPERPLASIA ASSOCIATED WITH MICROCALCIFICATIONS. B. CALCIFIED FIBROADENOMA. C. FIBROCYSTIC CHANGES WITH MICROCALCIFICATIONS. D. SCLEROSING ADENOSIS. E. SCLEROSING INTRADUCTAL PAPILLOMA. F. UNREMARKABLE SKIN. COMMENT: Estrogen receptor, progesterone receptor and HER-2/neu immunostains will be ordered and subsequently reported in an. addendum. Immunostaining for e-cadherin and myosin heavy chain confirm the interpretation of changes in the right. breast tissue.

expanded version (tokens=1389) : 
 Histological classification: The biopsy report reveals a diagnosis of infiltrating ductal carcinoma (IDC) with two lesions in the lower outer quadrant, and nuclear grade 3 ductal carcinoma in-situ (DCIS), solid type, with comedo-type necrosis, comprising less than 5% of the tumor. The IDC is further classified as Luminal B subtype.

Subtype: Luminal B

Necrosis: Comedo-type necrosis in the DCIS component

Tumor infiltrating lymphocytes: No mention of tumor infiltrating lymphocytes

Histological grade: Nottingham score of 9 out of 9 (tubules 3, nuclei 3, mitosis 3)

Nuclear grade: Grade 3 for DCIS

Lymphovascular invasion: Identified

Calcification: Microcalcifications found in the right breast tissue, and atypical ductal hyperplasia associated with microcalcifications

Receptor status: Immunostaining with appropriate positive and negative controls shows that the tumor is strongly positive for estrogen receptor (ER), progesterone receptor (PR), and HER2/neu. ER staining is 1+ in 30% of cells, PR staining is 0 in 70% of cells, and HER2/neu staining is strongly positive (score 3+), observed in more than 10% of tumor cells.

Ancillary testing results: Surgical margins are negative for both IDC and DCIS. One lymph node was positive for

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=1565) : 
 Total mastectomy was performed on a patient with Ca in their left breast. The diagnosis reports infiltrating ductal carcinoma (IDC) comprising two lesions in the lower outer quadrant, and nuclear grade 3 ductal carcinoma in-situ (DCIS), solid type, with comedo-type necrosis of <5% tumor. Luminal B is the subtype. Lymphovascular invasion was identified. Surgical margins of IDC were negative. ER/PR/HER2/neu testing reveals HER2/neu’s strong positivity (3+) and ER positive at 1+. Two lymph nodes out of two were positive for metastatic carcinoma.

