prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Normal, page 1 / 1. copy No. Examination: Histopathological examination. Gender: F. Material: Multiple organ resection - left breast 1. Expected time of examination: up to 8 working days. Clinical diagnosis: Cancer of the left breast. PCI: Carcinonia invasivum G3. Results of immunohistochemical examination: No estrogen receptors detected in neoplastic cell nuclei. Progesterone receptors found in less than 10% of neoplastic cell. nuclei. HER2 protein stained with Ventana's Pathway HER-2/neu (4B5) Rabbit Monoclonal Antibody. Negative reaction in. invasive cancerous cells (Score=1+). Compliance validate. Macroscopic description: Left. breast, sized 26 x 18 x 5 cm, removed along with axillary tissues sized 4 x 1 x 2 cm and a skin flap of 16 x 11 cm. Weight 220. g. Tumour sized 3.5 x 2.5 x 3.0 cm found in the upper inner quadrant, located 4 cm from the upper edge, 0.5 cm from the base. and 3.8 cm from the skin. Microscopic description: Carcinoma ductale invasivum - NHG3 (3+3+2: 9 mitoses/10 HPF - visual area: 0.55mm). Mamilla sine laesionibus. Glandular tissue showing lesions: mastopathia fibrosa. Axillary lymph nodes: Lymphonodulitis chronica (No I). Histopathological diagnosis: Carcinoma ductale invasivum mammae sinistrae. Invasive ductal carcinoma of the left breast. (NHG3, p 12, pNO).

expanded version (tokens=790) : 
 The pathology report states that the patient had a multiple organ resection of the left breast due to a diagnosis of left breast cancer. The macroscopic description of the tumor found in the upper inner quadrant showed that it was sized 3.5 x 2.5 x 3.0 cm, located 4 cm from the upper edge, 0.5 cm from the base, and 3.8 cm from the skin.

The microscopic description revealed that the patient had invasive ductal carcinoma (IDC) of the left breast with a histological grade of NHG3 (3+3+2). The tumor cells had 9 mitoses per 10 high power fields (HPF), with a visual area of 0.55mm. The report also indicates that there were no lesions found on the mamilla, but the glandular tissue showed lesions of mastopathia fibrosa.

The report further mentions that the axillary lymph nodes showed lymphonodulitis chronica (No I), which means that the lymph nodes had chronic inflammation with no evidence of cancer spread.

In addition to the histological classification, the report also includes information on receptor status. The immunohistochemical examination revealed that estrogen receptors were not detected in the neoplastic cell nuclei, but progesterone receptors were found in less than 10% of the neoplastic cell nuclei. The HER2 protein was stained negative in invasive cancerous cells with a score of 1+.



prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=981) : 
 The patient had a multiple organ resection of the left breast due to invasive ductal carcinoma. The tumor measured 3.5 x 2.5 x 3.0 cm and was located in the upper inner quadrant. The histological grade was NHG3 (3+3+2), with no lesion on mamilla but lesions of mastopathia fibrosa in glandular tissue. Axillary lymph nodes showed lymphonodulitis chronica, indicating no spread of cancer. Estrogen receptors were not detected, progesterone receptors were found in less than 10% of neoplastic cell nuclei, and HER2 protein was stained negative in invasive cells with a score of 1+.

