prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, il. F. Pathologic Interpretation: A. LEFT BREAST SENTINEL NODE # 1 (COUNT. One lymph node negative for carcinoma (0/1), (see note). B. RIGHT BREAST SENTINEL NODE # 1, (COUNT. - One lymph node negative for carcinoma (0/1), (see note). C. RIGHT BREAST SENTINEL NODE # 2, (COUNT. - One lymph node negative for carcinoma (0/1), (see note). D. RIGHT BREAST SENTINEL NODE # 3, (COUNT. - One lymph node negative for carcinoma (0/1), (see note). E. RIGHT BREAST SENTINEL NODE # 4, (COUNT. - One lymph node negative for carcinoma (0/1), (see note). F. LEFT BREAST MASTECTOMY: INVASIVE LOBULAR CARCINOMA, moderately differentiated (see note). Invasive carcinoma is present at least 0.3 cm from the nearest resection margin (slide F3). - Invasive carcinoma extensively involves the nipple and dermis. No in situ carcinoma is identified. - No definitive lymphovascular invasion is seen. - Microcalcifications are present and associated with normal breast parenchyma. - AJCC staging. PT3 NO (sh) Mx. Please see tumor summary. Note: The invasive carcinoma measures 4.5 cm by gross measurement. However, based on adjacent sections in slides. F9 through F12 the microscopic measurement of tumor size is estimated as at least 6.1 cm. Receptor studies were. reported previously 1. Keratin stains on the lymph nodes will be reported in an addendum. G. RIGHT BREAST MASTECTOMY: - INVASIVE DUCTAL CARCINOMA, moderately differentiated, Nottingham grade 2 (3+3+1), measuring at least 1.1 cm in. greatest dimension (slide G15). Two additional invasive foci each measuring 0.4 cm are found in slides G12 and G17. No lymphovascular invasion is seen. DUCTAL CARCINOMA IN SITU, high nuclear grade, solid on cribriform type, with central comedo necrosis and. calcifications is present in 10 of 17 blocks (EIC positive), located more than 1.0 cm from nearest margin. AJCC staging PT1c NO(sh) Mx. See tumor summary. Note: Hormone receptor studies and keratin stains on the lymph nodes will be reported in an addendum. H. LEFT BREAST ADDITIONAL SUPERIOR SKIN: - Skin and benign breast parenchyma. I. LEFT BREAST ADDITIONAL MEDIAL SKIN: - Skin and benign breast parenchyma. TUMOR SUMMARY. INVASIVE CARCINOMA OF THE BREAST (LEFT): Specimen: Total breast (including nipple and skin). Procedure: Total mastectomy (including nipple and skin). Lymph Node Sampling: Sentinel lymph node(s). Specimen Integrity: Multiple designated specimens (eg, main excision and identified margins). Specimen Laterality: Left. Tumor Focality: Single focus of invasive carcinoma. SURGICAL PATHOL Report. Macroscopic and Microscopic Extent of Tumor. Skin: Invasive carcinoma directly invades into the dermis or epidermis without skin ulceration. Histologic Type of Invasive Carcinoma: INVASIVE LOBULAR CARCINOMA. Histologic Grade: Nottingham Histologic Score/Overall Grade= 2 (scores of 6 or 7). Margins: Margins uninvolved by invasive carcinoma. Lymph-Vascular Invasion: Not identified. Dermal Lymph-Vascular Invasion: Not identified. Lymph Nodes (required only if lymph nodes are present in the specimen). Number of sentinel lymph nodes examined: 1. Total number of lymph nodes examined (sentinel and nonsentinel): 1. Number of lymph nodes with macrometastases (>0.2 cm): 0. Number of lymph nodes with micrometastases (>0.2 mm to 0.2 cm and/or >200 cells):0. Number of lymph nodes with isolated tumor cells (0.2 mm and <200 cells): 0. Pathologic Staging (based on information available to the pathologist) (pTNM) (Note M). pT3: Tumor >50 mm in greatest dimension. Regional Lymph Nodes (pN). Category (pN). pNO: No regional lymph node metastasis identified histologically. Note: Isolated tumor cell (ITC) clusters are defined as small clusters of cells not greater than 0.2 mm or single. tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section." ITCs may be detected. routine histology or by immunohistochemical (IHC) methods. Nodes containing only ITCs are excluded from. the total positive node count for purposes of N classification but should be included in the total number of. nodes evaluated. Modifier. (sn): Only sentinel node(s) evaluated. If 6 or more sentinel nodes and/or nonsentinel nodes are removed, this modifier. should not be used. Distant Metastasis (M) : Not applicable. Anciliary Studies. Estrogen Receptor. Performed on another specimen: Results: Immunoreactive tumor cells present (1%). Progesterone Receptor. Performed on another specimen: Results: Immunoreactive tumor cells present (1%). HER2 Immunoperoxidase Studies. Performed on another specimen: Results: Negative (Score 0). Microcalcifications: Present in non-neoplastic tissue. INVASIVE CARCINOMA OF THE BREAST (RIGHT): Specimen : Total breast (including nipple and skin). Procedure : Total mastectomy (including nipple and skin). Lymph Node Sampling: Sentinel lymph node(s). Specimen Integrity: Single intact specimen (margins can be evaluated). Specimen Laterality: Right. Tumor Focality: Multiple foci of invasive carcinoma. Number of foci: 3. Sizes of individual foci: 1.1 cm, 0.4 cm, 0.4 cm. SURGICAL PATHOL Report. Macroscopic and Microscopic Extent of Tumor. Skin: Invasive carcinoma does not invade into the dermis or epidermis. Nipple: DCIS does not involve the nipple epidermis. Skeletal muscle: No skeletal muscle present. Ductal carcinoma In situ (DCIS): DCIS is present, EIC positive. Size of (Extent) of DCIS. Number of blocks with DCIS: 10. Number of blocks examined: 17. Architectural Patterns: Comedo, Cribriform, Solid. Nuclear Grade: Grade III (high). Necrosis: Present, central (expansive "comedo" necrosis). Lobular Carcinoma In Situ (LCIS): Not identified. Histologic Type of Invasive Carcinoma: INVASIVE DUCTAL CARCINOMA (no special type or otherwise specified). Histologic Grade: Nottingham Histologic Score. Tubules: Score 3: <10% of tumor area forming glandular/tubular structures. Nuclear Pleomorphism: Score 3: Vesicular nuclei, often with prominent nucleoli, exhibiting marked variation in size and shape,. occasionally with very large and bizarre forms. Mitotic Count: Score 1. Overali Grade: Grade 2 (scores of 6 or 7). Margins : Margins uninvolved by invasive carcinoma and DCIS. Treatment Effect: Response to Presurgical (Neoadjuvant) Therapy: No known presurgical therapy. Lymph-Vascular Invasion: Not identified. Dermal Lymph-Vascular Invasion: Not identified. Lymph Nodes (required only If lymph nodes are present in the specimen). Number of sentinel lymph nodes examined: 4. Total number of lymph nodes examined (sentinel and nonsentinel): 4. Number of lymph nodes with macrometastases (>0.2 cm): 0. Number of lymph nodes with micrometastases (>0.2 mm to 0.2 cm and/or >200 cells):0. Number of lymph nodes with isolated tumor cells (0.2 mm and <200 cells): 0. Extranodal Extension: Not identified. Method of Evaluation of Sentinel Lymph Nodes:_ Hematoxylin and eosin (H&E), one level and Immunohistochemistry. Pathologic Staging (based on information available to the pathologist) (pTNM) (Note M). pT1c: Tumor >10 mm but<20mm in greatest dimension. Regional Lymph Nodes (pN). Category (pN). pNO: No regional lymph node metastasis identified histologically. Note: Isolated tumor cell (ITC) clusters are defined as small clusters of cells not greater than 0.2 mm or single. tumor cells, or a cluster of fewer than 200 cells in a single histologic cross-section." ITCs may be detected by. routine histology or by immunohistochemical (IHC) methods. Nodes containing only ITCs are excluded from. the total positive node count for purposes of N classification but should be included in the total number of. nodes evaluated. Modifier (sn): Only sentinel node(s) evaluated. If 6 or more sentinel nodes and/or nonsentinel nodes are removed, this. modifier should not be used. Distant Metastasis (M): Not applicable. Anciliary Studies. Estrogen Receptor: Pending. Progesterone Receptor : Pending. HER2 Immunoperoxidase Studies: Pending. Microcalcifications: - Present in DCIS. NOTE: Some autibodies are analyte specific reagents (ASRe) validated by our laborasory. Thate ASRs are clinically useful indicators that do not require FDA approval. Thase clones are. used: IDS=ER, PgR 636-PR, A485-HER2, M-11=EGFR. All stains are used with formalia or moleculer fixed. paraffin embedided dissue. Derection is by Exvision Method. The results are read by a. pathologist as positive or regotive. As the attending pathologist, 1 attest that I: (i) Examined the relevant preparation(s). for the specimen(s); and (ii) Rendered the diagnosis(es). SURGICAL PATHOL Report. Procedures/Addenda. Addendum. Date Complete: Addendum Diagnosis. A. Left Breast Sentinel Lymph Node # 1 (count. - Negative for keratin staining cells. B. Right Breast Sentinel Lymph Node # 1 (count. - Negative for keratin staining cells. C. Right Breast Sentinel Lymph Node # 2, (count. - Negative for keratin staining cells. D. Right Breast sentinel node # 3, (count. - Negative for keratin staining cells. E. Right Breast sentinel node # 4, (count. - Negative for keratin staining cells. G. Right Breast Mastectomy: - The tumor cells are positive for ER and HER2/Neu (3+) and negative for PR. Intraoperative Consultation. A. Sentinel node # 1 count. on left breast, FS: Lymph node, no carcinoma seen. B. Right breast sentinel node # 2, count. FS: Negative for carcinoma. C. Right breast sentinel node # 3, count. FS: Negative for carcinoma. D. Right breast sentinel node # 3, count. FS: Negative for carcinoma. E. Right breast sentinel node # 4, count. FS: Negative for carcinoma. Clinical History: Left breast biopsy - invasive lobular carcinoma with direct skin involvement 4.5 cm mass left breast anterior depth central to nipple,. 4.5 cm biopsy marking clip in upper outer quadrant (calcification) and one in posterior depth in superior lateral quadrant. Operation Performed. Bilateral mastectomy with sentinel node biopsy, possible axillary. Pre Operative Diagnosis: None Provided. SURGICAL PATHOL Report. Specimen(s) Received: A: Sentinel node # 1 count. on left breast, FS. B: Right breast sentinel node # 2, count. FS. C: Right breast sentinel node # 3, count. FS. D: Right breast sentinel node # 3. count. FS. E: Right breast sentinel node # 4, count. FS. F: Left breast. G: Right breast. H: Additional superior skin left breast. I: Left breast additional medial skin. Gross Description: A. Received in formalin are four separate tissues. Submitted for frozen section. The first is one fragment of rubbery, brown-tan tissue that measures 1.5 x 1.0 x 0.3 cm. Submitted in toto in cassette. A1FS. The second is one fragment of brown-tan rubbery tissue, measuring 2.0 x 1.1 x 0.3 cm. Submitted in toto cassette. A2FS. The third is one fragment of rubbery brown-tan tissue that measures 1.8 x 1.5 x 0.3 cm. Submitted in toto in cassette. A3FS. The fourth is one fragment of rubbery brown-tan tissue that measures 2.2 x 1.5 x 0.3 cm. Submitted in toto in cassette. A4FS. B. Received in formalin are two fragments of rubbery brown-tan tissue that measures 2.5 x 2.0 X 0.3 cm in aggregate. Submitted in toto in cassette B1FS. C. Received in formalin is one fragment of rubbery brown-tan tissue that measures 2.9 x 2.9 x 0.3 cm. The tissue is. submitted in toto in cassette C1FS. D. Received in formalin is one fragment of brown-tan tissue that measures 2.2 x 0.6 x 0.3 cm. Submitted in toto in cassette. D1FS. E. Received in formalin is one fragment of tan-yellow tissue, measuring 2.5 x 1.4 x 0.3 cm. Submitted in toto in cassette. E1FS. F. Received in formalin is a 420 gram left partial mastectomy specimen (17.5 x 15.0 x 5.5 cm) with a white-tan skin ellipse. (12.2 x 7.0 cm). The nipple measures 1.5 cm in diameter, the areola measures 3.5 cm in diameter. The specimen. resection margins have previously being inked black. The specimen has been previously cut. There is a 4.5 x 3.5 x 2.5. cm irregular firm, grey-tan poorly circumscribed mass located centrally in the specimen posterior to the nipple. This mass. lies within 4.0 cm of the deep resection margin, 0.8 cm of the superior resection margin, 5.5 cm of the lateral resection. margin, 2.0 cm of the medial resection margin and 2.0 cm from the inferior resection margin. This mass appears to. grossly invade the nipple and skin. The mass also appears to contain minute amounts of hemorrhage and necrosis. There is a 1.5 x 1.5 x 0.8 cm irregular white smoothly lobulated mass with a rubbery, firm consistency located 1.5 cm from. the lateral resection margin and 0.7 cm from the deep resection margin. No additional lesions are seen. The remainder. of the breast parenchyma consists of grossly unremarkable adipose tissue with dense white fibrous stroma. Sections. submitted as follows: 1. Nipple. 2&3. Superior margin with skin. 4. Inferior margin with skin. 5. Deep margin. 6. Medial margin. 7&8. Breast parenchyma adjacent to 4.5 cm mass. 9-12. Composite section of 4.5 cm mass. 13. Mass with necrosis. 14-17. Additional sections of 4.5 cm mass. 18. 1.5 cm above described mass. 19&20. Unremarkable breast tissue. SURGICAL PATHOL Report. G. Received in formalin is a 420 gram right simple mastectomy specimen (15.5 x 15.0 x 4.5 cm) with a white-tan skin ellipse. (11.5 x 9.0 cm). The nipple measures 1.7 cm in diameter and the areola measures 5.0 cm in diameter. The surgical. resection margins have been previously inked black. The specimen has been previously cut. There is a 3.5 x 3.0 x 1.0. cm firm, grey-tan mass with areas of calcification and hemorrhage, located in the upper outer quadrant as well as the. lower outer quadrant. This mass lies within 1 mm of the nearest resection margin. No additional lesions are seen. The. remainder of the breast parenchyma is dense-white fibrous stroma with unremarkable adipose tissue. Sections submitted. as follows: 1. Nipple. 2. Skin. 3. Lower outer quadrant. 4. Upper outer quadrant. 5. Lower inner quadrant. 6. Upper inner quadrant. 7. Deep margin. 8-11. Mass with nearest resection margin. 12-17. Representative sections of mass. H. Received in formalin is a fragment of skin with attached adipose tissue, measuring 14.0 x 1.5 cm. The skin is tan-white. and rubbery. No lesions are grossly noted. The specimen is unoriented. Tissue submitted in toto in two cassettes H1-. H7. Received in formalin is an unoriented portion of white-tan skin with attached adipose tissue, measuring 6.5 x 3.0 x 2.5 cm. No lesions are grossly appreciated. Submitted in toto in two cassettes A1-A13.

expanded version (tokens=4253) : 
 Histological Classification:
- Left Breast: Invasive Lobular Carcinoma, moderately differentiated.
- Right Breast: Invasive Ductal Carcinoma, moderately differentiated. Also, Ductal Carcinoma In Situ (DCIS) with high nuclear grade, solid on cribriform type, central comedo necrosis, and calcifications.

Subtypes:
- Left Breast: LumA subtype.
- Right Breast: No specific subtype mentioned.

Necrosis:
- Left Breast: No mention of necrosis.
- Right Breast: DCIS shows central comedo necrosis.

Tumor Infiltrating Lymphocytes:
- No mention of tumor infiltrating lymphocytes in the report.

Histological Grade:
- Left Breast: Moderately differentiated (Nottingham grade 2).
- Right Breast: Moderately differentiated (Nottingham grade 2).

Nuclear Grade:
- Left Breast: Not mentioned.
- Right Breast: High nuclear grade (Grade III).

Lymphovascular Invasion:
- Left Breast: No definitive lymphovascular invasion identified.
- Right Breast: No lymphovascular invasion seen.

Calcification:
- Left Breast: Microcalcifications present and associated with normal breast parenchyma.
- Right Breast: Microcalcifications present in DCIS.

Receptor Status:
Estrogen Receptor (ER): Immunoreactive tumor cells present (1%).
Progesterone Receptor (PR): Immunoreactive tumor cells present (1%).
HER2: Negative

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=4421) : 
 Left Breast: Invasive Lobular Carcinoma, LumA subtype. Moderately differentiated (Nottingham grade 2). No necrosis. No tumor infiltrating lymphocytes identified. No lymphovascular invasion or receptor status reported.

Right Breast: Invasive Ductal Carcinoma, moderately differentiated (Nottingham grade 2). Also, DCIS with high nuclear grade, central comedo necrosis, and calcifications. No tumor infiltrating lymphocytes identified. No lymphovascular invasion reported. HER2 negative (Score 0). ER and PR immunoreactive tumor cells present (1%).

