prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, Revised. F. Pathologic Interpretation: AMENDMENT,. A. SUPERIOR MEDIAL MARGIN, RULE OUT TUMOR: - No malignancy seen. B. SENTINEL NODE #1: - Microscopic foci of carcinoma are highlighted by Keratin (1/1). C. SENTINEL NODE #2: - No malignancy seen in one lymph node (0/1). - Immunohistochemistry for keratin is negative for carcinoma. D. SENTINEL NODE #3: - Metastatic carcinoma to one lymph node (1/1) with extracapsular extension. E. RIGHT BREAST MASS: - Invasive ductal carcinoma Nottingham grade 2 (3+2+1); 4.2 cm in greatest dimension. - Specimen margins are negative for tumor closest margins are anterior and superior, 0.2 cm (See Tumor Summary). - Lymphovascular invasion is identified. F. ADDITIONAL AXILLARY FAT: - No malignancy seen in one lymph node (0/1). G. ADDITIONAL SUPERIOR MARGIN: - Microscopic focus of invasive ductal carcinoma, 0.1 cm, adjacent to inked resection margin. The focus of invasive carcinoma is present at the inked margin adjacent to previous resection. The "new" inked margin is free of tumor. - Lymphatic tumor emboli are identified. H. RIGHT AXILLARY CONTENTS: - No malignancy seen in nineteen lymph nodes (0/19). I. ADDITIONAL AXILLARY CONTENTS LEVEL 2-3 LYMPH NODES: - No malignancy seen in two lymph nodes (0/2). Tumor Summary: Specimen: Partial breast. Procedure: - Excision without wire-guided localization. Lymph Node Sampling: - Sentinel lymph nodes. - Axillary dissection. Specimen Integrity: - Multiple designated specimens. Specimen Size: - Greatest dimension: 8.5 cm. Additional dimension: 6 x 5 cm. Laterality: (Right. Tumor Size: SURGICAL PATHOL Report. - Greatest dimension of largest focus of invasion over 0.1 cm: 4.2 cm. - Additional dimensions: 3.8 x 2.8 cm. Tumor Focality: - Single focus of invasive carcinoma. Macroscopic and Microscopic Extent of tumor: - Skin: Skin is not present. - Skeletal muscle: No skeletal muscle present. Lobular Carcinoma IN Situ (LCIS): - Not identified. Histologic Type of Invasive Carcinoma: - Invasive ductal carcinoma. Histologic Grade: - Glandular (Acinar)/Tubular Differentiation: - Score 3: <10% of tumor area forming glandular/tubular structures. - Nuclear Pleomorphism: - Score 2: Cells larger than normal with open vesicular nuclei, visible nucleoli, and moderate variability in both size and. Shape. - Mitotic Count: - Score 1. - Overall Grade: - Grade 2: scores of 6 or 7. Margins: - Margins negative for invasive carcinoma. Lymph-Vascular Invasion: - Present. Lymph Nodes: - Number of sentinel lymph nodes examined: 3. - Total number of lymph nodes examined (sentinel and Nonsentinel): 25. - Number of lymph nodes with macrometastases (>0.2 cm): 2. Extranodal Extension: - Present. Method of Evaluation of Sentinel Lymph Nodes: - Hematoxylin and eosin (H&E), one level. - Immunohistochemistry. Pathologic Staging: - Primary Tumor: pT2: Tumor >20 mm but <50 mm in greatest dimension. - Regional Lymph Nodes: pN1a: Metastases in 1 to 3 axillary lymph nodes, at least 1 metastasis greater than 2.0 mm. - Distant Metastasis: Not applicable. Anciliary Studies: Estrogen Receptor: - Performed on another specimen: Results: Immunoreactive tumor cells present (1%). Progesterone Receptor. - Performed on another specimen: Results: Immunoreactive tumor cells present (1%). HER2/neu. - Performed on another specimen: Results: Negative (Score 0). Clinical History: - Palpable mass. Pathologic Staging (pTNM): pT2, N1a, M-not applicable. PREVIOUSLY ISSUED DIAGNOSIS: A. SUPERIOR MEDIAL MARGIN, RULE OUT TUMOR: - No malignancy seen. B. SENTINEL NODE #1: - No malignancy seen in one lymph node (0/1). - Immunohistochemistry for keratin to follow. C. SENTINEL NODE #2: SURGICAL PATHOL Report. - No malignancy seen in one lymph node (0/1). - Immunohistochemistry for keratin to follow. D. SENTINEL NODE #3: - Metastatic carcinoma to one lymph node (1/1) with extracapsular extension. E. RIGHT BREAST MASS: - Invasive ductal carcinoma Nottingham grade 2 (3+2+1); 4.2 cm in greatest dimension. - Specimen margins are negative for tumor closest margins are anterior and superior, 0.2 cm (See. Tumor. Summary). Lymphovascular invasion is identified. F. ADDITIONAL AXILLARY FAT: - No malignancy seen in one lymph node (0/1). G. ADDITIONAL SUPERIOR MARGIN: - Microscopic focus of invasive ductal carcinoma, 0.1 cm, adjacent to inked resection margin. - Lymphatic tumor emboli are identified. H. RIGHT AXILLARY CONTENTS: - No malignancy seen in nineteen lymph nodes (0/19). I. ADDITIONAL AXILLARY CONTENTS LEVEL 2-3 LYMPH NODES: - No malignancy seen in two lymph nodes (0/2). Tumor Summary: Specimen: - Partial breast. Procedure: - Excision without wire-guided localization. Lymph Node Sampling: - Sentinel lymph nodes. - Axillary dissection. Specimen Integrity: - Multiple designated specimens. Specimen Size: - Greatest dimension: 8.5 cm. . Additional dimension: 6 x 5 cm. Laterality: - Right. Tumor Size: Greatest dimension of largest focus of invasion over 0.1 cm: 4.2 cm. - Additional dimensions: 3.8 x 2.8 cm. Tumor Focality: - Single focus of invasive carcinoma. Macroscopic and Microscopic Extent of tumor: - Skin: Skin is not present. - Skeletal muscle: No skeletal muscle present. Lobular Carcinoma IN Situ (LCIS): - Not identified. Histologic Type of Invasive Carcinoma: - Invasive ductal carcinoma. Histologic Grade: - Glandular (Acinar)/Tubular Differentiation: - Score 3: <10% of tumor area forming glandular/tubular structures. - Nuclear Pleomorphism: - Score 2: Cells larger than normal with open vesicular nuclei, visible nucleoli, and moderate variability in bothisize and. Shape. - Mitotic Count: - Score 1. - Overall Grade: - Grade 2: scores of 6 or 7. Margins: SURGICAL PATHOL Report. - Margins positive for invasive carcinoma. Specify margin and Extent of involvement: Superior margin, focal. Lymph-Vascular Invasion: - Present. Lymph Nodes: - Number of sentinel lymph nodes examined: 3. - Total number of lymph nodes examined (sentinel and Nonsentinel): 25. - Number of lymph nodes with macrometastases (>0.2 cm): 1. Extranodal Extension: - Present. Method of Evaluation of Sentinel Lymph Nodes: - Hematoxylin and eosin (H&E), one level. - Immunohistochemistry. Pathologic Staging: - Primary Tumor: pT2: Tumor >20 mm but 50 mm in greatest dimension. - Regional Lymph Nodes: pN1a: Metastases in 1 to 3 axillary lymph nodes, at least 1 metastasis greater than 2.0 mn. - Distant Metastasis: Not applicable. Anciliary Studies: Estrogen Receptor: Performe. another specimen. Results: Immunoreactive tumor cells present (1%). Progesterone p. ed on another specimen: Results: Immunoreactive tumor cells present (1%). HER?. med on another specimen: Results: Negative (Score 0). Clinical History: - Palpable mass. Pathologic Staging (pTNM): pT2, N1a, M-not applicable. NOTE: Nome immunhisruchen. NO analyse specific reagents (ASRs) validated by owr lahnvatory. These ASRs are nseful indicators that do mat require FDA approval. These clomes are used: IDS-ER. 7 All stains are used with formalin or molecular frxed, paraffin emhedded rissue. Detection is by Emision Method. The rdmits are read by. pathologies as positive or negative. As the attending pathologist, / attest that 1: (i) Examined the relevant preparation(s). for the specimen(s): and (ii) Rendered the diagnosis(es). MD. Amendments. Amended. Reason: Diagnosis editing/clarification. New information provided to Dr. by physician. Previous Signout Date: Intraoperative Consultation. A. Superior medial margin, rule out tumor, FS: No tumor seen. B. Sentinel node #1, FS: Negative for carcinoma (touch prep and frozen). C. Sentinel node #2, FS: Negative for carcinoma (touch prep and frozen). D. Sentinel node #3, FS: Atypical cells on touch prep-carcinoma cannot be excluded. FS: Metastatic carcinoma in lymph node. : MD. SURGICAL PATHOL Report. MD. Clinical History: female with right breast mass. Biopsy shows invasive ductal carcinoma. Operation Performed. Lumpectomy right breast with sentinel node. Pre Operative Diagnosis: Breast cancer. Specimen(s) Received: A: Superior medial margin, rule out tumor, FS. B: Sentinel node #1, FS. C: Sentinel node #2, FS. D: Sentinel node #3, FS. E: Right breast mass. F: Additional axillary fat. G: Additional superior margin. H: Right axillary contents. I: Additional axillary contents level 2-3 lymph nodes. Gross Description: A. Received fresh are two yellow-tan tissue fragments,measuring up to 1.0 cm in length. In toto in one cassette for frozen. B. Received fresh is a light brown lymph node 1.5 x 1.0 cm. in toto in one cassette for frozen. C. Received fresh is a lymph node, measuring 2.0 x 1.5 cm. In toto in one cassette for frozen. D. Received fresh is a lymph node, measuring 1.2 x 1.0 cm. In toto in one cassette for frozen. E. Received in formalin is a yellow-tan fibroadipose tissue fragment, weighing 89 grams, measuring 8.5 x 6.0 x 5.0 cm. The. specimen is oriented with a short superior, long lateral and double stitch deep margin. Inked as follows: Superior in blue,. inferior in green, deep black, anterior yellow, lateral orange and medial red. Cross section through the specimen shows. yellow-tan cut surface. There is an ovoid, markedly firm, tumoral mass, measuring 4.2 x 3.8 x 2.8 cm. The mass is. within 2 mm from superior and anterior inferior margin. No other firm masses were grossly identified. Sections submitted. as follows: 1&2. Composite resection of the largest axis of the mass from antero-inferior to superior margin. 3-5. Additional section of the mass in relation with the antero-inferior margin. 6&7. Section of the mass in relation with the deep resection margin. 8. Medial margin. 9. Lateral margin. F. Received in formalin are multiple yellow-tan adipose tissue fragments, measuring 6.0 x 4.0 x 1.0 cm in aggregate. No. lymph nodes were grossly identified. Sections from the fat tissue in three cassettes. G. Received in formalin is a yellow-tan adipose tissue fragment (additional superior margin), measuring 6.0 x 3.0 1.0. cm. Multiple sutures orient the specimen as a true margin. The true margin in green. The opposite margin in black. Cross. section through the specimen shows a yellow-tan cut surface. No masses were grossly present. Submitted ih. toto. in. eight cassettes. H. Received in formalin are multiple yellow-tan fibroadipose tissue fragments, measuring 10.0 x 7.0 x 3.0 cm in aggregates. Twenty lymph nodes are present, measuring up to 0.8 x 0.7 cm in greatest dimension. Sections as follows: 1. Two lymph nodes in toto. 2-8. Three lymph nodes in toto per cassette. I. Received are multiple yellow-tan fibroadipose tissue fragments, measuring 5.0 x 3.0 x 1.0 cm. Four lymph nodes are. identified, measuring up to 0.6 x 0.4 cm. Sections as follows: 1&2. Two lymph nodes in toto per cassette. SURGICAL PATHOL Report.

expanded version (tokens=3325) : 
 Histological classification:
- Subtype: LumA, Revised
- Invasive ductal carcinoma Nottingham grade 2 (3+2+1), 4.2 cm in greatest dimension
- No Lobular Carcinoma IN Situ (LCIS) identified

Necrosis:
- No mention of necrosis in the report

Tumor infiltrating lymphocytes:
- No specific mention of tumor infiltrating lymphocytes in the report

Histological grade:
- Glandular (Acinar)/Tubular Differentiation: Score 3 (less than 10% of tumor area forming glandular/tubular structures)
- Nuclear Pleomorphism: Score 2 (cells larger than normal with open vesicular nuclei, visible nucleoli, and moderate variability in both size and shape)
- Mitotic Count: Score 1
- Overall Grade: Grade 2 (scores of 6 or 7)

Lymphovascular invasion:
- Lymphovascular invasion is identified

Calcification:
- No specific mention of calcification in the report

Receptor status and ancillary testing results:
- Estrogen Receptor: Immunoreactive tumor cells present (1%)
- Progesterone Receptor: Immunoreactive tumor cells present (1%)
- HER2/neu: Negative (Score 0)

Other ancillary testing:
- Immunohistochemistry for Keratin: Microscopic foci of carcinoma highlighted by Keratin in sentinel node #1 (

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3502) : 
 Breast Pathology Report: LumA, Revised. Invasive ductal carcinoma Nottingham grade 2 (3+2+1), 4.2 cm. No necrosis identified. No mention of tumor infiltrating lymphocytes. Histologic grade: Glandular/Tubular Differentiation (Score 3), Nuclear Pleomorphism (Score 2), Mitotic Count (Score 1). Lymphovascular invasion present. Estrogen receptor (1%), Progesterone receptor (1%). HER2/neu negative (Score 0). No calcification mentioned. Immunohistochemistry positive for Keratin in sentinel node #1.

