prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Normal, A) LEFT BREAST, TOTAL MASTECTOMY: INVASIVE DUCTAL CARCINOMA, MODIFIED BLACK'S NUCLEAR GRADE. 3. (POORLY DIFFERENTIATED). (SEE COMMENT). DUCTAL CARCINOMA IN SITU (DCIS), MODIFIED BLACK'S NUCLEAR GRADE 3. (HIGH GRADE), SOLID AND CRIBRIFORM PATTERNS WITH COMEDONECROSIS. INVASIVE CARCINOMA MEASURES 1.2 X 1.0 X 1,0 CM. MARGINS WIDELY FREE, INVASIVE CARCINOMA IS PRESENT 2.2 CM FROM. CLOSEST INFERIOR MARGIN. No lymphovascular identified. Nipple, no tumor present. (B) LEFT AXILLARY SENTINEL LYMPH NODE #1, EXCISIONAL BIOPSY: One lymph node, no tumor present (0/1). Immunohistochemistry for cytokeratin is negative for carcinoma. (C) LEFT AXILLARY SENTINEL LYMPH NODE #2, EXCISIONAL BIOPSY: One lymph node, no tumor present (0/1). Immunohistochemistry for cytokeratin is negative for carcinoma. (D): RIGHT BREAST, TOTAL MASTECTOMY: INVASIVE DUCTAL CARCINOMA, MODIFIED BLACK'S NUCLEAR GRADE 3. (POORLY DIFFERENTIATED). (SEE COMMENT). DUCTAL CARCINOMA IN SITU (DCIS), MODIFIED BLACK'S NUCLEAR GRADE 3. (HIGH GRADE), SOLID CRIBRIFORM PATTERNS WITH COMEDONECROSIS AND. MICROCALCIFICATIONS. INVASIVE CARCINOMA MEASURES 1.4 CM IN GREATEST SLIDE DIMENSION. DCIS PRESENT 0.35 CM FROM LATERAL ANTERIOR MARGIN. INVASIVE CARCINOMA IS PRESENT 0.4 CM FROM LATERAL ANTERIOR MARGIN. FOCAL LYMPHOVASCULAR INVASION PRESENT. Nipple, no tumor present. (E) RIGHT SENTINEL LYMPH NODE #1, EXCISIONAL BIOPSY: One lymph node, no tumor present (0/1). Immunohistochemistry for cytokeratin are negative for carcinoma. (F) RIGHT SENTINEL LYMPH NODE #2, EXCISIONAL BIOPSY: One lymph node, no tumor present (0/1). Immunohistochemistry for cytokeratin are negative for carcinoma. Entire report and diagnosis completed by. COMMENT. In specimen A, LEFT BREAST, the invasive carcinoma has areas of lymphocytic infiltration but. also has infiltrating borders. Immunohistochemical studies demonstrate that the invasive. carcinoma is positive for CK903, CK5/6 and vimentin. This report is issued to give immunohistochemistry results. Immunohistochemical staining is. performed on a representative formalin-fixed, paraffin-embedded section of INVASIVE DUCTAL. CARCINOMA, left breast, block A3. MARKER. POSITIVE. SCORE. Estrogen Receptor. Low Positive (1-9%). ( 1 %. N/A. Progesterone Receptor. Negative. 0 %. N/A. HER-2/neuoverexpression Negative. 0 %. 0. This report is issued to give immunohistochemistry results. Immunohistochemical staining is. performed on a representative formalin-fixed, paraffin-embedded section of INVASIVE DUCTAL. CARCINOMA, right breast, block D6. MARKER. % POSITIVE. SCORE. Estrogen Receptor. Low Positive (1-9%). 1%. Progesterone Receptor. Negative. 0%. HER-2/neu. overexpression. Negative. focal 5 %. 2+. Due to the above HER-2/neu immunohistochemical staining result, gene. copy level (HER-2/neu: CEP17 signal ratio) will be evaluated by FISH. and a separate report will be issued. FOOTNOTE. Estrogen receptor was assessed by immunohistochemistry using antibody 6F11. I. Progesterone receptor was assessed by immunohistochemistry using antibody PgR1294(. HER-2/neu was assessed by immunohistochemistry using antibody AB8 (1. GROSS DESCRIPTION. (A) LEFT BREAST, SHORT STITCH SUPERIOR, LONG LATERAL FOR IMMEDIATE. CONSULTATION - Received is a 16 x 13 x 3.0 cm breast with attached ellipse of tan grossly. unremarkable skin measuring 6.0 x 3.2 cm. The 1.2 x 1.0 cm nipple is everted. Surgical margin. is inked. Sectioned from lateral-to-medial aspect into eleven slices. Slice #8 contains nipple. Cut surface of slice #6 shows an ill-defined, firm pink gray tumor measuring 1.2 x 1.0 x 1.0 cm. It. is 2.2 cm away from inferior margin, 2.0 cm from deep margin, 2.5 cm from the skin. Superior,. lateral and medial margins are widely free Representative sections are submitted. INK CODE: Superior - blue; inferior - orange; deep - black. SECTION CODE: A1, A2, nipple; A3, A4, slice #6, superior aspect of the tumor; A5, A6,. slice #6 inferior aspect of the tumor; A7, inferior surgical margin slice #6; A8, tissue superiorly to. the tumor slice #6; A9, deep surgical margin slice #6; A10, A11, tissue laterally to the tumor slice. #5; A12, A13, slice #7 tissue immediately to the tumor slice #7; A14, A15, upper outer quadrant;. A16, A17, lower outer quadrant; A18, A19, upper inner quadrant; A20, lower inner quadrant; A21,. mid lower portion. Fragment of tumor and normal tissue are submitted to tumor bank. (B) LEFT AXILLARY SENTINEL LYMPH NODE #1 FOR FROZEN SECTION IN VIVO 83, EX. VIVO 153 - Received is a single lymph node embedded into fatty tissue measuring 1.2 x 1.0 x 0.4. cm. Cut surface is light tan. The section is entirely submitted for frozen section in cassette B. FS/DX: NO TUMOR PRESENT. (C) LEFT AXILLARY SENTINEL LYMPH NODE #2 FOR FROZEN SECTION, IN VIVO 253, EX. VIVO 281 - Received is a single lymph node measuring 1.0 x 0.8 x 0.4 cm. For frozen section. received is a single lymph node measuring 1.3 x 0.9 x 0.5 cm. Cut surface is light tan. Section. entirely submitted for frozen section in cassette C. FS/DX: NO TUMOR PRESENT. (D) RIGHT BREAST, SHORT STITCH SUPERIOR, LONG STITCH LATERAL FOR IMMEDIATE. CONSULTATION - Received is a 14 x 13 x 5.5 cm breast with a 6.5 x 2.5 cm ellipse of tan-skin. The 1.2 x 1.0 cm nipple is everted. Surgical margin is inked. Sectioned from the medial-to-lateral. aspect into ten slices. Slice #7 contains nipple, slice #9 contains an ill-defined, infiltrating,. indurated tumor measuring 1.2 x 1.3 x 1.1 cm. Radiological clip is present within the mass. The. lesion is 0.7 cm from the closest lateral surgical margin, 1.5 cm from deep, 5.0 cm away from the. superior surgical margin, 4.9 cm from the inferior and 2.5 cm away from the skin. Tissue toward. the medial aspect of the breast shows dense fibrous tissue. Representative sections are. submitted. INK CODE: Superior - blue; inferior - orange; deep - black. SECTION CODE: D1, D2, nipple; D3, D4, D5, slice #9 superior aspect of the tumor; D6,. D7, D8, slice #9 inferior aspect of the tumor; D9, slice #9, tissue inferiorly to the tumor; D10,. slice #9 tissue superiorly to the tumor; D11, deep margin slice #9; D12, slice #9 inferior margin;. D13, D14, perpendicular sections of the lateral surgical margin; D15, D16, slice #8, tissue. medially to the tumor; D17, D18, upper inner quadrant; D19, D20, lower inner quadrant. (E) RIGHT SENTINEL LYMPH NODE #1 IN VIVO 130, EX VIVO 170 - Received for frozen. section is a single lymph node embedded in fatty tissue measuring 2.0 x 1.0 x 0.7 cm. Cut. surface is light tan. Section is entirely submitted for frozen section in cassettes E1, E2. FS/DX: NO TUMOR PRESENT. (F) RIGHT SENTINEL LYMPH NODE #2 FOR FROZEN SECTION IN VIVO 38, EX VIVO 108. Received a single lymph node embedded in fatty tissue measuring 2.0 x 0.9 x 0.8 cm. Cut. surface is white-tan. Section entirely submitted for frozen section in blocks F1, F2. FS/DX: NO TUMOR PRESENT. CLINICAL HISTORY. Breast cancer. SNOMED CODES. T-04050, M-85003. "Some tests reported here may have been developed and performance characteristics. determined by. These tests have not been. specifically cleared or approved by the U.S. Food and Drug Administration.". Released by: Start of ADDENDUM. ADDENDUM. This modified report is being issued to report the results of HER-2/neu FISH. Addendum completed bv. SPECIMEN SOURCE. Right breast. SUMMARY. Tissue section of the invasive carcinoma : vas evaluated for HER-2/neu gene. amplification by interphase fluorescence in situ hybridization technique using the. HER-2/neu DNA Probe Kit (LSI HER-2/neu SpectrumOrange/CEP17. Slide adequacy is satisfactory. Sixty tumor nuclei were counted and showed an average of 1.62. copies of LSI HER-2/neu gene per nucleus and an average of 1.45 copies of CEP17 per nucleus. Negative and positive controls (established by. 1 with this batch are. appropriate. Two representative images have been archived. INTERPRETATION. The tumor cells demonstrated no amplification of the HER-2/neu gene copy levels (HER-2/neu: CEP17 signal ratio: 1.11). The following guideline has been established for HER-2/neu testing: Normal HER-2/neu levels: < 1.80; equivocal HER-2/neu levels: 1.80-2.20; - amplified HER-2/neu. levels: > 2.20. (Ref: Arch Patholo Lab Med. 2007; 131:18-43). NOTES. The LSI HER-2/neu probe is specific for the HER-2/neu gene Locus (17q 11.2-q12) and the CEP. 17 DNA probe is specific for the alpha satellite DNA sequence at the centromeric region of. Chromosome 17 (17 p11.1 -q11.2). This test has been cleared and approved for specific uses by the U.S. Food and Drug. Administration. Its system is operating within the performance specifications stated in the product. insert. Released by:

expanded version (tokens=2973) : 
 This breast pathology report includes the following information:

1. Histological classification: The patient has invasive ductal carcinoma (IDC) in both the left and right breast, as well as ductal carcinoma in situ (DCIS) in both breasts. The IDC in the left breast is a modified Black's nuclear grade 3 (poorly differentiated) while the IDC in the right breast is a modified Black's nuclear grade 3 (poorly differentiated). The DCIS in both breasts is a modified Black's nuclear grade 3 (high grade), with solid and cribriform patterns and comedonecrosis.

2. Subtype: The subtype is not mentioned in the report.

3. Necrosis: Comedonecrosis is present in the DCIS in both breasts.

4. Tumor infiltrating lymphocytes: The IDC in the left breast has areas of lymphocytic infiltration.

5. Histological grade: The IDC in both breasts is a modified Black's nuclear grade 3 (poorly differentiated).

6. Nuclear grade: Both DCIS are a modified Black's nuclear grade 3 (high grade).

7. Lymphovascular invasion: Focal lymphovascular invasion is present in the IDC in the right breast.

8. Calcification: Microcalcifications are present in the DCIS in the right breast.

9. Receptor status: Estrogen receptor (ER) is low positive (1-9%) in the IDC in both breasts. Pro

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3153) : 
 The breast pathology report shows invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS) in both the left and right breasts, along with areas of lymphocytic infiltration and comedonecrosis. The IDC in both breasts is a modified Black's nuclear grade 3 (poorly differentiated). ER is low positive (1-9%) while progesterone receptor (PR) is negative for both IDCs. Focal lymphovascular invasion is present in the IDC of the right breast. Microcalcifications are noted in DCIS of the right breast. HER-2/neu overexpression is absent but requires additional testing.

