prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, MODIFIED REPORT - REVIEW ADDENDUM SECTION. DIAGNOSIS. (A) LEFT BREAST, SKIN-SPARING TOTAL MASTECTOMY: TWO FOCI OF INVASIVE LOBULAR CARCINOMA, NOTTINGHAM HISTOLOGIC GRADE 1 (WELL-. DIFFERENTIATED). (SEE COMMENT 1). AT 6 O'CLOCK INVASIVE CARCINOMA MEASURES 1.5 X 0.4 CM IN CONTIGUOUS SECTIONS/SLICES. INVASIVE CARCINOMA IS PRESENT 0.6 CM FROM CLOSEST INFERIOR MARGIN. FOCAL DUCTAL CARCINOMA IN SITU (DCIS), LOW GRADE, SOLID PATTERN. AT 2 O'CLOCK INVASIVE CARCINOMA MEASURES 3.5 X 3.0 CM IN CONTIGUOUS SECTIONS/SLICES. MARGINS ARE WIDELY FREE, PRESENT AT LEAST 1.0 CM FROM CLOSEST SUPERIOR MARGIN. FOCAL DUCTAL CARCINOMA IN SITU (DCIS), LOW GRADE, SOLID AND CRIBRIFORM PATTERNS. Associated fibroadenoma. Atypical lobular hyperplasia, atypical ductal hyperplasia. Secretory changes. C Burst MOS C50.9. Reactive changes consistent with previous biopsy site. Dense fibrosis consistent with capsule. Microcalcifications present in association with invasive and in situ carcinoma, and with benign breast tissue. Nipple and skin, no tumor present. Skeletal muscle, no tumor present. Intact breast implant, gross examination only. (B) LEFT AXILLARY SENTINEL LYMPH NODE #1, EXCISIONAL BIOPSY: MICROMETASTASIS PRESENT IN ONE OF ONE LYMPH NODE. (SEE COMMENT 2). TUMOR CELLS ARE HIGHLIGHTED BY CYTOKERATIN IMMUNOSTAIN AND ARE PRESENT WITHIN AN AREA. MEASURING 0.75 X 0.1 MM IN LARGEST SINGLE SLIDE DIMENSION. (C) LEFT AXILLARY SENTINEL LYMPH NODE #2, EXCISIONAL BIOPSY: SINGLE CYTOKERATIN POSITIVE ISOLATED TUMOR CELL PRESENT IN ONE OF ONE LYMPH NODE, MEASURES. 0.01 MM IN GREATEST SINGLE SLIDE DIMENSION. (SEE COMMENT 3). (D) LEFT AXILLARY SENTINEL LYMPH NODE #3, EXCISIONAL BIOPSY: Fibroadipose tissue, no lymphoid tissue identified. Immunohistochemical stain for cytokeratin is negative. COMMENT. 1). Immunohistochemical stains for biologic markers are pending. 2) In specimen B, the frozen sections are reviewed but the tumor cells are not evident. In H&E stained permanent sections, the. largest group of tumor cells can be identified but the tumor cells are bland and well differentiated. The tumor cells are best seen. on immunostained slides and are present in four areas in the lymph node sections. The majority of the tumor cells are clustered. within a 0.75 x 0.1 mm area. In addition, isolated tumor cells, singly or in pair, are present in three other regions of the lymph node. sections. 3) In specimen C, tumor cells are not evident in the frozen and permanent H&E sections. GROSS DESCRIPTION. (A) LEFT BREAST, SHORT SUPERIOR, LONG LATERAL - A 16.0 X 15.0 X 7.0 cm skin sparing total mastectomy specimen that. is oriented by the surgeon with a short stitch designating superior and a long stitch designating lateral. The specimen is partly. surfaced by a 4.5 X 3.5 cm ovoid portion of pale tan wrinkled skin. Located on the surface of the skin is an everted nipple. surrounded by a rim of areola that measure 1.2 and 3.5 cm in diameter, respectively. The specimen is serially sectioned from. medial to lateral into eleven slices. The nipple is located in slice #5. In slices #2 through #10 there is a 12.0 x 12.0 x 2.7 cm breast. implant and cavity lined by a pink-white smooth, glistening, fibrous capsular tissue. The specimen contains an intact. brand breast implant filled with a translucent viscous material. Identifying information is as follows: The breast implant measures 12.0 x 12.0 X 2.7 cm and is for gross only. Radiographs are taken of the specimen and display. at. the. 6. o'clock. position, within slices #5 and #6, a 1.5 x 1.0 x 0.5 cm firm, gray-white mass that grossly comes to within 0.6 cm. from the anterior inferior margin, 3.5 cm from the deep margin, 3.5 cm from the nipple and abuts the implant capsule. There is a. metal biopsy clip located in this mass in slice #5. At the 2 o'clock position, in slices #8 through #10, there is a 3.5 x 3.0 x 1.3 cm. firm gray-white mass that grossly comes to within 3.0 cm from the deep margin, 1.0 cm from the anterior superior margin, 2.5 cm. from the anterior inferior margin, and abuts the implant capsule. There is a metal biopsy clip located in slice #9 in this mass. Remaining cut surfaces are 60% yellow glistening adipose tissue and 40% gray-white fibrous tissue. Some tissue has been given. to tumor bank for research purposes. INK CODE: Blue - superior; orange - inferior; black - deep. SECTION CODE: A1, A2, nipple from slice #5; A3, A4, 6 o'clock mass to inferior margin from slice #5; A5, slice #4,. capsule and inferior margin, medial to 6 o'clock mass; A6, mass slice #6; A7, slice #7, lateral to 6 o'clock mass; A8, slice #7,. lateral to 2 o'clock mass; A9, 2 o'clock mass, slice #8; A10, 2 o'clock mass, slice #9; A11, 2 o'clock mass in area of clip, slice #9;. A12, 2 o'clock mass with superior margin, slice #9; A13, deep margin from slice #9; A14, 2 o'clock mass, slice #10; A15,. representative sections from slice #11 (lateral margin), perpendicularly sectioned and adjacent to 2 o'clock mass; A16, upper inner. quadrant from slice #3; A17, upper inner quadrant from slice #4. IOA/DX: MARGINS ARE FREE GROSSLY/RADIOLOGIC. (B) LEFT AXILLARY SENTINEL LYMPH NODE #1, BLUE, IN VIVO 65, EX VIVO 117 - A 1.1 x 0.7 x 0.4 cm lymph node. SECTION CODE: B, one lymph node carially sectioned for frozen section diagnosis. FS/DX: NO TUMOR PRESENT. (C) LEFT AXILLARY SENTINEL LYMPH NODE #2, BLUE, IN VIVO 65, EX VIVO 27 - A 1.1 x 0.7 X 0.4 cm lymph node. SECTION CODE: C, one possible lymph node serially sectioned for frozen section diagnosis. FS/DX: NO TUMOR PRESENT. (D) LEFT AXILLARY SENTINEL LYMPH NODE #3, BLUE, IN VIVO 65, EX VIVO 24 - A 2.0 x 1.5 x 0.5 cm portion of. fibroadipose tissue. The tissue is dissected; however, a definite lymph node is not grossly identified. Cut surfaces are composed. of unremarkable fibroadipose tissue. SECTION CODE: D, entire specimen. IOA/DX: NO GROSSLY IDENTIFIED LYMPH NODE. DEFER TO PERMANENT. CLINICAL HISTORY. Left breast cancer. SNOMED CODES. T-04050, M-Y2003. "Some tests reported here may have been developed and performance characteristics determined by. These tests have not been. specifically cleared or approved by the U.S. Food and Drug Administration.". Start of ADDENDUM. ADDENDUM. COMMENT. This report is issued to give Immunohistochemistry results. Immunohistochemical staining is performed in our lab on a. representative paraffin-embedded section of INVASIVE LOBULAR CARCINOMA, left breast, block A4, 6 o'clock. MARKER. Clone/Vendor. STAINING. SCORE. Estrogen Receptor. 6F11-. Positive. 95 %. Strong. Progesterone Receptor. PgR1294(. Positive. 95 %. Strong. Ki-67. MIB1 (. Low. 5 %. N/A. HER2 overexpression. AB8 (. Negative. N/A. This report is issued to give Immunohistochemistry results. Immunohistochemical staining is performed in our lab on a. representative paraffin-embedded section of INVASIVE LOBULAR CARCINOMA, left breast, block A11, 2 o'clock. MARKER. Clone/Vendor. STAINING. SCORE. Estrogen Receptor. 6F11-. Positive. >95 %. Strong. Progesterone Receptor. PgR1294(. Positive. >95 9 %. Strong. Ki-67. MIB1 (. Low. 5%. N/A. HER2 overexpression. AB8 (. Negative. N/A. 1+. COMMENT. Due to the above HER2 immunohistochemical staining result, gene copy level (HER2: CEP17 signal ratio) will be evaluated by. FISH and a separate report will be issued. FOOTNOTE. Breast specimens used for determining prognostic / predictive markers are fixed in formalin for 6-48 hours. For ER & PR: Positive. 10 100%. Low Positive. 1-9%. For Ki-67 Low Positive. <17%. Moderate Positive. 17-35%. High Positive. >35%. For. Her. 2: Positive. cases are those with uniform, intense and complete membrane staining in greater than 30% of invasive tumor cells (Score 3+). Negative cases. are defined as those with no staining (Score 0) or weak, incomplete membrane staining in any proportion of cells (Score 1+). Equivocal or indeterminate cases are. those with strong staining in less than or equal to 30% of cells, or complete membrane staining that is either non-uniform or weak in intensity, but with. obvious. circumferential distribution in at least 10% of tumor cells (Score +2). Reference Wolff AC, Hammond EH, Swartz JN et al. American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for. Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer. Arch Pathol Lab Med. 007;131:18-43. Start of ADDENDUM #2. ADDENDUM. For FISH results, please see.

expanded version (tokens=2855) : 
 The breast pathology report describes a case of left breast cancer. The main points of the report are:

1) Histological classification: Subtype LumA, which is a type of breast cancer that is hormone receptor (ER/PR) positive and HER2 negative.

2) Invasive Carcinoma: The report indicates two foci of invasive lobular carcinoma, with a size of 1.5 x 0.4 cm and 3.5 x 3.0 cm. The histological grade of the first focus is 1, which means it is well-differentiated. The proximity of invasive carcinoma to the closest margins is noted.

3) Ductal Carcinoma in situ (DCIS): There are two foci of DCIS, measured as 0.6 cm and 3.5 x 3.0 cm respectively. The DCIS is of low grade, with solid and cribriform patterns.

4) Additional Findings: Atypical lobular hyperplasia, atypical ductal hyperplasia, secretory changes, dense fibrosis consistent with a capsule, and microcalcifications are present in association with invasive and in situ carcinoma, and with benign breast tissue. Associated fibroadenoma is also noted.

5) Lymph Nodes: The left axillary sentinel lymph node shows micrometastasis in one of one lymph nodes. A single cytokeratin positive isolated tumor cell is present in one of one lymph nodes. No

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=3039) : 
 Report: Left breast cancer of subtype LumA; two foci of invasive lobular carcinoma, size of 1.5 x 0.4 cm, and 3.5 x 3.0 cm respectively; two foci of ductal carcinoma in situ (DCIS), low grade with solid and cribriform patterns; atypical lobular hyperplasia, atypical ductal hyperplasia, secretory changes, dense fibrosis consistent with a capsule, and microcalcifications are present; lymph node involvement in one out of one axillary sentinel lymph nodes with micrometastasis. ER/PR positive and HER2 negative. Breast implant present.

