prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, RUN DATE : RUN TIME : RUN USER: ACCT # : AGE/SX: ROOM. REG DR: BED: SPEC #: RECD. COLL. TIME IN FORMALIN: 29:21. nrs. CLINICAL INFORMATION: Pre-Op Diagnosis: Breast CA. Remarks: Specimen(s : Right breast stitch marks axillary contents. MICKOSCOPIC DIAGNOSTS. BREAST. RIGHT. MODIFIED RADICAL MASTECTOMY: MULTIFOCAL INVASIVE DUCTAL CARCINOMA - SEE COMMENT. LARGEST TUMOR MEASURES 4 CM: GRADE 2. ANGIOLYMPHATIC INVASION PRESENT. SEVEN (7) OF EIGHTEEN (18) AXILLARY LYMPH NODES POSITIVE FOR METASTATIC CARCINOMA. WITH FOCAL EXTRACAPSULARY EXTENSION PRESENT. MARGINS NEGATIVE. COMMENT(S). In addition to the two larger tumors present within the upper outer quadrant, a tumor is. also present associated with the nipple measuring 2 cm. This section was evaluated with. E-cadherin with appropriate controls demonstrating that the infiltrating carcinoma is. strongly positive for a E-cadherin confirming ductal type. Additionally, a couple of the. lymph nodes were evaluated with PanKeratin stain with appropriate controls. A section from. the larger mass was evaluated for a breast prognostic panel. PROTOCOL FOR EXAMINATION OF SPECIMENS WITH INVASIVE CARCINOMA OF THE BREAST. PROCEDURE. Total mastectomy. LYMPH NODE SAMPLING: Axillary disection. SPECIMEN LATERALITY: Right. HISTOLOGIC TYPE OF. INVASIVE CARCINOMA. Invasive ductal carcinoma (NOS). TUMOR SIZE: Greatest dimension of largest focus 4 cm. HISTOLOGIC GRADE : Nottingham histologic score. Glandular differentiation Score 3. Nuclear pleomorphism Score 2. Mitotic index: Score 1. Overall grade: Grade 2. TUMOR FOCALITY: Multiple foci of invasive carcinoma. DUCTAL CARCINOMA IN SITU: No DCIS is present. MACROSCOPIC AND MICROSCOPIC. RUN DATE : RUN TIME: RUN USER: Continued). SPEC #. COMMENT (s). EXTENT OF TUMOR: Skin: Invasive carcinoma directly invades into the. dermis without skin ulceration. MARGINS: Margins uninvolved by invasive carcinoma. Distance from closest margin: 3 cm. LYMPH NODES: Number of sentinel lymph nodes examined : 0. Total number of lymph nodes examined (sentinel and. non-sentinel) : 18. Number of lymph nodes with macrometastasis: 5. Number of lymph nodes with micrometastasis: 2. PATHOLOGIC STAGING: Primary tumor: pT2. Regional lymph nodes: pN2a. Distance metastasis: Not applicable. ANCILLARY STUDIES: See microscopic description (ER+, PR+ Her2-). GROSS DESCRIPTION: Received fresh for selection of tissue for tissue banking labeled with the patient's name. is a modified radical mastectomy specimen. The axillary contents measure 16 x 11 x 4 cm,. palpation of which reveals clinically suspicious lymph nodes. The breast weighs ,457. g. and measures 30 x 18 x 6 cm. Skeletal muscle fibers are present on the deep margin. À large mass is palpated in the upper outer quadrant. The deep margin adjacent to this area. is inked blue. The breast is covered by a 30 x 18 cm ellipse of dark brown skin. The. nipple and areolar complex is centrally placed. The nipple measures 2.5 cm in diameter and. is somewhat firm on palpation The breast is serially sectioned revealing a. well-circumscribed grayish-white tumor within the upper outer quadrant measuring 3 x 3.5 x. measures 4 3 cm. The tumor lies 1.5 cm from the skin surface. On further evaluation. there. cm À portion of the tumor is provided to the tissue bank coordinator. The deep margin. is an apparent separate tumor in the upper outer quadrant with a core needle biopsy. track. and this tumor measures 1.5 x 1 x 1 cm. This tumor is well away from the surgical margins. The remainder of the breast tissue is fatty in nature. No other discrete lesions are. identified. Examination of the axillary contents reveals multiple lymph nodes which range. from 0.5 cm to 3.5 cm in greatest dimension each. Some of these are grossly involved by. tumor. Some are fatty in nature. Cassette Summary: 1. nipple. 2. deep margin adjacent to larger tumor. sections of larger tumor. 8. tissue between larger tumor and smaller tumor. 9.10 -. sections of smaller tumor. 11-13-. sections of lateral. central. and medial breast tissue. respectively. 14. two highest axillary lymph nodes. 15. smaller whole lymph nodes. 16-21-. one lymph node each sectioned and entirely submitted. 22.23-. representative section of two large fatty lymph nodes. 24-26-. representative section of each grossly positive lymph node. RUN DATE. RUN TIME. RUN USER. Continued). SPEC #. MICROSCOPIC DESCRIPTION: BREAST PROGNOSTIC PANEL - LARGEST TUMOR. ASSAY TYPE. % TUMOR STAINED. INTENSITY. Estrogen Receptor. 100. 3. POSITIVE. Progesterone Receptor. 85. 2. POSITIVE. Ki-67. 24. 2. HIGH. SCORE. 1+. NEGATIVE. Her2/neu. REFERENCE RANGES: ER/PR; Negative <1%, Positive >=1%. : Ki-67; Low <10%, Boderline 10-20%, High >20%. Her2/neu: Negative 0-1+, Equivocal 2+, Positive 3+. Her2/neu results are reflexed to FISH. All immunohistochemical staining and the. were performed at. performed scoring and. interpretation utilizing. Clone MIB-1. Antibody clones: Clone 6F11;. Clone PgP1294; Ki-67,. Her2/neu,. CAP/ASCO guidelines for ER and PgR IHC: formalin fixation time 6-72 hours; cold ischemia. time 1 hour or less. CAP/ASCO guidelines for Her2 testing: formalin fixation time 6-48. hours: cold ischemia time 1 hour or less. Testing outside of these guidelines may affect. results. INTRAOPERATIVE CONSULTATION: RIGHT BREAST TISSUE: TUMOR ADEQUATE FOR TISSUE BANKING WITH PORTION OF TUMOR PROVIDED TO TISSUE BANK. COORDINATOR. Image. Image. Image. Image. (signature on file).

expanded version (tokens=1908) : 
 - The subtype of breast cancer is LumA.
- Multifocal invasive ductal carcinoma was found in the right breast.
- The largest tumor measures 4 cm and is grade 2.
- Angiolymphatic invasion was present.
- Seven out of eighteen axillary lymph nodes were positive for metastatic carcinoma with focal extracapsular extension.
- Margins were negative.
- The tumor is invasive ductal carcinoma (NOS) with glandular differentiation score 3, nuclear pleomorphism score 2, and mitotic index score 1; overall grade is 2 (Nottingham histologic score).
- No ductal carcinoma in situ was found.
- Invasive carcinoma directly invades into the dermis without skin ulceration.
- The distance from the closest margin is 3 cm.
- The number of lymph nodes examined was 18.
- Five lymph nodes had macrometastasis, and two had micrometastasis.
- The primary tumor staging was pT2, and the regional lymph node staging was pN2a.
- The tumor is ER+ and PR+ but HER2-. Ki-67 was high (24%).
- Immunohistochemical staining and interpretation were performed.
- Formalin fixation time was 6-72 hours, and cold ischemia time was 1 hour or less.
- The tumor was adequate for tissue banking.
- The cancer is strongly positive for E-cadherin confirming ductal type. 


prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2068) : 
 Right breast, LumA subtype, 4cm invasive ductal carcinoma (grade 2), with angiolymphatic invasion and metastasis to 7 of 18 axillary lymph nodes (N2a). ER+ and PR+ but HER2-. Ki-67 is high at 24%. No ductal carcinoma in situ found. Margins were negative. Tumor invades the dermis without skin ulceration and is strongly positive for E-cadherin confirming ductal type. Formalin fixation within guidelines. Adequate for tissue banking.

