prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype Normal, FINAL PATHOLOGIC DIAGNOSIS. A. Right axillary sentinel lymph node #1, biopsy: - Metastatic ductal carcinoma (1.3cm) involving single lymph node (1/1). B. Right axillary sentinel lymph node #2, biopsy: - One lymph node, no tumor (0/1). C. Right axillary sentinel lymph node #3, biopsy: - One lymph node, no tumor (0/1). D. Right axillary non sentinel lymph node, biopsy: - One lymph node, no tumor (0/1). E. Right breast, wire-guided lumpectomy: - Invasive ductal carcinoma, SBR III, multiple foci (largest 1.3cm). - Ductal carcinoma in situ high grade, solid, cribriform and micropapillary. types with central necrosis and associated calcifications; DCIS spans entire. specimen (8cm in greatest dimension). F. Right breast, new inferior lateral margin, excision: - Ductal carcinoma in situ, intermediate grade, microscopic foci (largest 5mm). - Microscopic foci (each 1mm) of DCIS present at outer medial aspect of specimen. G. Right breast, new outer lateral margin, excision: - Ductal carcinoma in situ, rare microscopic foci (largest 1mm). - DCIS >1cm from nearest new margin. Breast Pathologic Parameters. 1. Invasive carcinoma: A. Microscopic measurement: Multifocal; largest focus (measures 1.3cm). B. Composite histologic (modified SBR) grade: III (largest focus). - Architecture: 2. - Nuclear grade: 3. - Mitotic count: 3. C. Associated intraductal carcinoma in situ (DCIS): - High grade, solid, cribriform and micropapillary types. - DCIS involves entire specimen and spans 8cm in greatest dimension. 2. Excisional biopsy margins: Positive. - DCIS present at medial margin, <1mm from anterior, posterior, lateral,. superior, and inferior margins (tumor approaches margins at multiple foci. throughout specimen). - Invasive carcinoma at inferior and 1mm from posterior margin; additional. margins greater than 2mm away. 3. Blood vessel and lymphatic invasion: Present in breast parenchyma. 4. Axillary lymph nodes: Positive (1/4). - Size of largest metastatic deposit: 13 mm. - Extranodal extension: absent. 5. Special studies. - ER: Weak expression in 10% of invasive tumor nuclei. - PR: No expression. - Her2/neu antigen (FISH): Amplified (ratio: 7.6). 6. pTNM (AJCC, 7th edition, 2010): pT1c(m), N1(sn), MX. Effective. is Checklist utilizes the 7th edition TNM staging. system for breast of the American Joint Committee on Cancer (AJCC) and the. International Union Against Cancer (UICC). has1. Interpretation performed by the Attending Pathologist and reviewed with the. Resident/Fellow. Clinical History: Patient is a. -year-old female with right breast IDC undergoing lumpectomy and. sentinel lymph node biopsy. Specimens Received: A: Sentinel lymph node #1. B: Sentinel lymph node #2. C: Sentinel lymph node #3. D: Non-sentinel lymph node. E: Right wire-guided lumpectomy. F: Right breast new inferior lateral margin. G: New outer lateral margin. Gross Description: The specimens are received in seven containers each labeled with the patient's. name and medical record number. A. The first container is additionally identified as, 'sentinel lymph node #1'. Received fresh and placed in formalin the specimen consists of a 1.5x1x1cm. lymph node which is serially sectioned and entirely submitted in cassette A1. B. The second container is additionally identified as, 'sentinel lymph node. #2'. Received fresh and placed in formalin the specimen consists of a 1x 0.5 X. 0.3 cm lymph node which is bisected and is entirely submitted in cassettes B1. C. The third container is additionallyidentified as, 'sentinel lymph node #3'. Received fresh and placed in formalin the specimen consists of a 0.7 x 0.3 x 0.3. cm lymph node which is entirely submitted in cassette C1. D. The fourth container is additionally identified as, 'non-sentinel lymph. node'. Received fresh and placed in formalin the specimen consists of a 0.5 X. 0.3 x 0.3 cm lymph node which is entirely submitted in cassette D1. E. The fifth container is additionally identified as, 'right wire guided. lumpectomy'. Received fresh on a radiographic grid is a 102 gm lumpectomy. specimen measuring 8 cm from medial to lateral, and 8 in cm from superior to. inferior and 3 cm from anterior to posterior. The specimen is oriented with a. short suture designating the superior pole and a long suture designating the. lateral pole. There is a wire entering the antero-lateral aspect of the specimen. through grid coordinate E5. Accompanying the specimen is an x-ray demonstrating. a metallic clip located in grid coordinate E3. There is a circled mass in grid. positions C3, C4, D3, D4, centered on the clip. The wire enters the specimen in. grid coordinates E5 terminates in E3. 2 other areas of calcifications are. circled in grid coordinates D6 (#2) and F4-F5 (#3). The margins are inked as follows: anterior - black;. posterior - red;. superior - blue;. inferior - green;. medial - yellow;. lateral - violet. The specimen is serially sectioned from medial to lateral into 8 slices. The. area of calcifications noted in grid D6 begins in the slides #2 and extends. laterally the tumor the main to mass and measures 3 X 2 x 1.5 cm. is found in. the slices #2 and 3 adjacent to the red and green ink. The main mass, which is. irregular and firm, is present in slices #5 to #7 and measures 3.5 X 2.5 X 2 cm. It is present adjacent to red ink and is 1 cm from black ink, 3 cm from green. ink, 1.5 cm away from blue ink. The area of calcification noted in grid F4 and. F5 is present in the slices numbers 7 and activated ink measuring 1.5 X 1.1 x 1. cm and is continuous with the main mass. The metallic clip is identified in. slice 6. The wire enters the specimen in slice 5 and terminates in slice 5. The. remainder of the breast parenchyma is white-yellow and lobulated with no. additional masses or lesions. Entire mass including both calcified area was has a largest dimension of 5 cm. Specimen is submitted in toto. Block summary: E1-E4: medial margin, slice 1. E5-E9: slice 2, area of calcification. E10-E23: slice 3, area of calcification. E24-E31: slice 4. E32-E44; slice 5. E45-E62: slice 6, clip in E49-E50. E63-E78: slice 7. E79-E86: lateral margin, slice 8. F. The sixth container is additionally identified as, 'right breast, new. inferior lateral margin'. Received fresh on the radiographic grid is a 13.5 gm,. 6.5 X 4 X 1.2 cm medial inferior lateral margin which is oriented as follows: - new outer lateral margin is marked with a long black stitch (violet). - new outer medial margin is designated with a short black stitch (yellow). - new outer anterior margin is designated with a short blue stitch (black). - new outer posterior margin is designated with a long blue stitch. (red). Inner cauterized margin is inked green. An area of calcification is noted on the. accompanying x-ray in grid D4-D5-E5. Specimen is a serially sectioned from. lateral to medial in to 14 slices. An area of calcification is present in slice. #6 and measures 1 X 0.5 X 0.3 cm. No other lesions are identified. The specimen. is entirely submitted from lateral to medial. F1: slice 1-3. F2: slice 4-5. F3: slice 6. F4: slice 7. F5-F6: slice 8. F7: slice 9. F8: slice 10. F9: slice 11. F10: slice 12. F11: slice 13-14. G. The seventh container is additionally identified as, 'new outer lateral. margin'. Received fresh ona radiographic grid is a 20 gm, 8 x 3.5 X 1 cm new. outer lateral margin. Specimen is oriented as follows. - new outer superior is designated with a short black stitch (blue). - new outer inferior is designated with a long black a stitch (green). - new outer anterior is designated with a short blue stitch (black). - new outer posterior is designated with a long blue stitch (red). Inner cauterized margin is inked violet. Specimen is serially sectioned from. lateral to medial into 14 slices and does not contain any distinct masses or. lesions. Specimen is submitted in toto in cassettes G1-14.

expanded version (tokens=2492) : 
 Histological Classification: The breast pathology report identifies the presence of invasive ductal carcinoma, SBR III, multiple foci (largest 1.3cm) and ductal carcinoma in situ (DCIS) high grade, solid, cribriform, and micropapillary types with central necrosis and associated calcifications. The tumor involves the entire specimen measuring 8cm in the greatest dimension.

Subtype: The report does not specify the subtype of the invasive ductal carcinoma.

Necrosis: The report mentions the presence of central necrosis in DCIS and associated calcifications.

Tumor Infiltrating Lymphocytes: There is no mention of tumor infiltrating lymphocytes in the report.

Histological Grade: The invasive ductal carcinoma is classified as SBR III, which indicates a high histological grade. The architecture score is 2, nuclear grade is 3, and the mitotic count is 3.

Nuclear Grade: The nuclear grade of the invasive ductal carcinoma is 3.

Lymphovascular Invasion: The report identifies the presence of blood vessel and lymphatic invasion in breast parenchyma.

Calcification: The report mentions the presence of associated calcifications in DCIS and a few areas of calcifications elsewhere in the breast tissue.

Receptor Status: The pathology results indicate that the tumor is ER weakly positive, PR negative, and Her2/neu amplified with a ratio of 7.6.

IHC: The report includes

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2646) : 
 The pathology report of a female breast tissue with IDC reveals grade III invasive ductal carcinoma. Multiple foci of DCIS with calcifications and central necrosis were also identified. Lymphovascular invasion was found, and margins were positive for DCIS in various sections. Metastatic cancer is seen in one of the four axillary lymph nodes examined. Receptor status shows ER weakly positive, PR negative, and Her2/neu amplified (7.6 ratio). The tumor infiltration of lymphocytes data is not discussed.

