prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, FINAL PATHOLOGIC DIAGNOSIS. A. Surgical hardware, right breast, removal: - Implant identified, gross examination only. B. Breast, right, modified radical mastectomy: - Invasive ductal carcinoma, three separate foci measuring 2.8 cm (main. lesion) grade II/III, 0.7 cm (satellite #1) grade II/III and 1.1 cm (satellite. #2) grade I/III, in greatest dimension, surgical margins negative (see. pathologic parameters and comment below). - Ductal carcinoma in situ, intermediate grade, solid and papillary types,. surgical margins negative. - Uninvolved breast tissue with fibrocystic changes. - Previous biopsy sites present. - One of ten axillary lymph nodes involved by metastatic carcinoma (1/10). C. Lymph nodes, right axillary, excision: - Two lymph nodes, negative for carcinoma (0/2). Breast Pathologic Parameters. 1. Invasive carcinoma: A. Gross measurement: Three foci - 2.8 cm (main lesion). 0.7 cm (satellite #1). 1.1 cm (satellite #2). B. Composite histologic (modified SBR) grade: II/III (main and. satellite #1). I/II (satellite #2). C. Associated intraductal carcinoma in situ (DCIS): - Within main mass (forming <10% of tumor volume). 2. Surgical margins: - DCIS 5.0 mm from closest margin (posterior). - Invasive carcinoma 5.0 mm from closest margin (posterior). - Additional margins widely free. 3. Blood vessel and lymphatic invasion: Present in breast parenchyma. 4. Nipple: Unremarkable. 5. Skin: Uninvolved. 6. Skeletal muscle: Absent. 7. Axillary lymph nodes: - Current specimen. One of twelve lymph nodes involved by metastatic carcinoma (1/12). - Size of largest metastatic deposit: 1.0 cm. - Extranodal extension: Present (1.0 mm; largest focus). - Sentinel node biopsies (. - Two of five sentinel lymph nodes involved by metastatic carcinoma. (2/5). - Size of largest metastatic deposit: 1.0 cm. - Extranodal extension: Absent. - Total: Three of seventeen lymph nodes involved by metastatic carcinoma. (3/17). 8. Special studies (see. - ER: Strong expression in >90% of invasive tumor nuclei (all three lesions). - PR: Strong expression in >90% of invasive tumor nuclei (all three lesions). - HER2 antigen (FISH): - Main lesion: Non-amplified (ratio: 1.2). - Satellite #1: Non-amplified (ratio: 1.5). - Satellite #2: (IHC): negative (0 - 1+). - Ki67: - Main lesion: 20%. - Satellite #1: 20%. - Satellite #2: 10%. 9. pTNM (AJCC, 7th edition, 2010): pT2(m), N1a, MX. Effective. this Checklist utilizes the 7th edition TNM staging. system for breast of the American Joint Committee on Cancer (AJCC) and the. International Union Against Cancer (UICC). Clinical History: Right Breast Cancer. Comment. P63 and myosin heavy chain immunohistochemical stains are performed and show a. loss of myoepithelium associated with the invasive component. Specimens Received: A: Right breast implant. B: Right breast with axillary contents. C: Additional nodes right axilla. Gross Description: The specimens are received in three containers each labeled with the patient's. name and medical record number. A. The first container is additionally identified as, 'right breast implant'. Received in container is a 14 x 14 x 4.5 cm white, round, plastic hardware. filled with liquid material. Gross photograph is taken. The specimen is for. gross evaluation only. B. The second container is additionally identified as, 'right breast with. axillary contents'. Received fresh and placed in formalin is a 268 gm simple. mastectomy specimen. There is a 15 x 6.5 cm capsule pocket implant in posterior. inferior aspect of specimen. The specimen isoriented with a double short suture. designating the superior aspect and a double long suture designating the lateral. aspect. The breast measures 15.5 cm from medial to lateral, 14 cm from superior. to inferior, and 2.3 cm from anterior to posterior. On the anterior surface is. 13.3 X 5.3 cm yellow-tan ellipse of skin with a 4.8 x 3.8 cm areola and a 1.3 x. 1 cm raised nipple. The nipple-areolar complex reveals no evidence of. ulceration or retraction. The specimen is inked as follows: anterior-superior - blue;. anterior-inferior - green;. posterior - black. The specimen is serially sectioned from lateral (slice #1) to medial into 13. slices to reveal a 2.8 x 1.8 x 1.5 cm grey-tan, irregular-shaped, rubbery lesion. (lesion #1) in slices #6 through #8, which is 0.3 cm from deep margin. There is. a 1.1 X 1.0 X 0.3 cm pink-tan, oval nodule (lesion #2) in slice #7, which abuts. the capsule pocket and less than 0.5 cm from lesion #1. There is a hemorrhagic. area of dense parenchyma measuring 2.8 X 1.5 X 1 cm in slices #9 through #10,. which is 1.2 cm from the deep margin. The remainder of the specimen consists of. approximately 30% dense gray-white fibrous breast parenchyma and 70% lobulated. yellow adipose tissue. No additional masses or nodules are grossly identified. Multiple gray-tan, rubbery axillary lymph nodes ranging from 0.3-1.2 cm are. dissected. Block summary: B1: nipple. B2: skin adjacent to lesion #1, slice 7. B3: Lesion #1, slice 6. B4: Lesion #1, slice 7. B5: Lesion #1, slice 8. B6: Lesion #2 and adjacent lesion #1, slice 7. B7: Lesion #3, slice 9. B8: Lesion #3, slice 10. B9: upper-outer quadrant slice 4. B10: lower-outer quadrant slice 5. B11: upper-inner quadrant slice 8. B12: lower-inner quadrant slice 11. B13: 4 lymph nodes. B14-B15: 3 lymph nodes. B16: One lymph node, trisected. B17: One lymph node, bisected. B18-B19: One lymph node, serial section. B20: 4 lymph nodes. C. The third container is additionally identified as, 'additional nodes right. axilla'. Received fresh and placed in formalin are 2 yellow-tan, soft tissue. fragments measuring 0.5-1.5, which are entirely submitted as C1. MD, PhD.

expanded version (tokens=2008) : 
 The pathology report describes a Luminal A subtype of breast cancer. The right breast underwent a modified radical mastectomy due to the presence of invasive ductal carcinoma in three separate foci, one measuring 2.8 cm (main lesion) and two satellite lesions measuring 0.7 cm and 1.1 cm, respectively. The invasive carcinoma is of modified SBR grade II/III (main and satellite #1) and I/II (satellite #2).

There is also ductal carcinoma in situ (DCIS), which is intermediate grade and consists of solid and papillary types. The surgical margins for both invasive carcinoma and DCIS are negative, except for the DCIS that is 5.0 mm from the closest margin (posterior). Blood vessel and lymphatic invasion are present in the breast parenchyma. There is also one of ten axillary lymph nodes involved by metastatic carcinoma, and two lymph nodes were negative for carcinoma out of the total twelve in excised right axillary lymph nodes.

Special studies were performed, including immunohistochemical stains, which shows strong expression of estrogen receptors (ER) and progesterone receptors (PR) in over 90% of invasive tumor nuclei in all three lesions. HER2 antigen was not amplified in the main lesion and satellite #1, while satellite #2 was HER2 negative. Ki67 is expressed in main lesion and satellite #1 (20%), and satellite #2 (10%).

The pTN

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2206) : 
 Report: LumA subtype of breast cancer found in the right breast. Invasive ductal carcinoma with three separate foci, one 2.8 cm main lesion with a modified SBR grade of II/III, one 0.7 cm satellite lesion with a grade of II/III and one 1.1 cm satellite lesion with a grade of I/II. Negative surgical margins for both invasive carcinoma and DCIS except for DCIS that is 5.0mm from closest margin (posterior).  One out of ten axillary lymph nodes involved with metastatic carcinoma while two were negative out of twelve excised right axillary lymph nodes tests performed showed Strong expression in >90% of invasive tumor nuclei for ER and PR,

