prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumA, PATHOLOGY EXAMINATION. CLIENT: soc. SEC #: ADDITIONAL: SPECIMEN(S) RECEIVED: A: Right breast lumpectomy needle localized short double stitch, superior margin "single long, lateral. B: Left breest sentinel node #1. C: Left breast sentinel node #2. D: Left breast needle localized subareolar blopsy - short double stitch superior, single long lateral margin. E: Left breast anterior margin stitch to mark tumor side. F: Left breast superior margin stitch to mark tumor side. G: Left breast medial margin stitch to mark tumor side. H: Left breast Inferior margin stich to mark tumor side. I: Left breast lateral margin "stitch to mark tumor side. J: Left breast posterior (deep) margin stitch to mark tumor side. K: Left breast, axillary sentinal node #3. L: Left breast needle localized lumpectomy short double stitch, superior margin single long. lateral. M: Left breast lumpectomy, new anterior margin stitch marks tumor alde. N: Left breast lumpectomy, new medial margin stitch marks tumor side. O: Left breest lumpectorny, new Inferior margin stitch marks tumor side. P: Left breast lump additional enterior margin. Q: Left breast lump additional inferior margin. R: Left breast lumpectomy new superior margin. CLINICAL DATA/HISTORY: Tissue banking - hx of right breast papiliary lesion. FINAL PATHOLOGIC DIAGNOSIS: A. RIGHT BREAST, NEEDLE LOCALIZED LUMPECTOMY: INTERMEDIATE GRADE DUCTAL CARCINOMA IN SITU, SOLID TYPE. 2 MM IN GREATEST EXTENT. <1 MM TO MEDIAL MARGIN. INTRADUCTAL PAPILLOMA WITH FLORID DUCTAL HYPERPLASIA. FIBROCYSTIC CHANGE. PREVIOUS BIOPSY SITE. SEE SYNOPTIC REPORT #1. B, C, K. LEFT BREAST SENTINEL NODES #1-3: THREE LYMPH NODES, NEGATIVE FOR METASTATIC CARCINOMA (0/3). D. LEFT BREAST, SUBAREOLAR, NEEDLE LOCALIZED LUMPECTOMY: MULTIFOCAL INVASIVE LOBULAR CARCINOMA. LARGEST FOCUS 1.2 MM IN GREATEST EXTENT. <1 MM TO MEDIAL MARGIN. 1 MM TO POSTERIOR MARGIN. INTRADUCTAL PAPILLOMA WITH FLORID DUCTAL HYPERPLASIA. FIBROCYSTIC CHANGE. PREVIOUS BIOPSY SITE. SEE SYNOPTIC REPORT #2. E-J,L-R. LEFT BREAST, NEEDLE LOCALIZED LUMPECTOMIES X2 WITH SEPARATELY SUBMITTED. MARGINS DESIGNATED AS ANTERIOR, SUPERIOR, MEDIAL, INFERIOR, LATERAL, POSTERIOR (DEEP),. NEW ANTERIOR, NEW MEDIAL, NEW INFERIOR, ADDITIONAL ANTERIOR, ADDITIONAL INFERIOR, NEW. SUPERIOR: MULTIFOCAL INVASIVE LOBULAR CARCINOMA. LARGEST FOCUS AT LEAST 2.3 CM. IN GREATEST DIMENSION. FINAL MARGINS NEGATIVE WITH CLOSEST BEING 3MM TO INFERIOR AND 9 MM TO. ANTERIOR. INTRADUCTAL PAPILLOMAS. FLORID DUCTAL HYPERPLASIA. FIBROCYSTIC CHANGE. SEE SYNOPTIC REPORT #2. SYNOPTIC REPORT #1 (RIGHT BREAST LUMPECTOMY): PROCEDURE: EXCISION WITH WIRE GUIDED LOCALIZATION. SPECIMEN LATERALITY: RIGHT. SIZE (EXTENT) OF DCIS: 2 MM IN GREASTEST EXTENT. NUMBER OF BLOCKS WITH DCIS: 1. NUMBER OF BLOCKS EXAMINED: 8. HISTOLOGIC TYPE: DUCTAL CARCINOMA IN SITU. ARCHITECTURAL PATTERN: SOLID. NUCLEAR GRADE: G2 (INTERMEDIATE). NECROSIS: NOT IDENTIFIED. MARGINS: UNINVOLVED BY DCIS. DISTANCE FROM CLOSEST MARGIN: <1 MM (MEDIAL). PATHOLOGIC STAGING: pTis (DCIS). ADDITIONAL PATHOLOGIC FINDINGS: INTRADUCTAL PAPILLOMA WITH FLORID HYPERPLASIA. FIBROCYSTIC CHANGE. ANCILLARY STUDIES: HORMONE RECEPTORS TO BE PERFORMED AND REPORTED IN AN. ADDENDUM. COLD ISCHEMIA TIME: 11 MINUTES. FORMALIN FIXATION TIME: 10 HOURS 33 MINUTES. SYNOPTIC REPORT #2 (LEFT BREAST SUBAREOLAR LUMPECTOMY): PROCEDURE: EXCISION WITH WIRE GUIDED LOCALIZATION. LYMPH NODE SAMPLING: SENTINEL LYMPH NODES. SPECIMEN LATERALITY: LEFT. HISTOLOGIC TYPE OF INVASIVE CARCINOMA: INVASIVE LOBULAR CARCINOMA. TUMOR SIZE: SIZE OF LARGEST INVASIVE CARCINOMA 1.2 MM IN GREATEST DIMENSION. HISTOLOGIC GRADE (NOTTINGHAM HISTOLOGIC SCORE): GLANDULAR I TUBULAR DIFFERENTIATION: SCORE 3. NUCLEAR PLEOMORPHISM: SCORE 1. MITOTIC RATE: SCORE 1. OVERALL GRADE: GRADE 1. TUMOR FOCALITY: MULTIPLE FOCI OF INVASIVE CARCINOMA. AT LEAST 2. SIZES OF INDIVIDUAL FOCI: RANGING FROM LESS THAN 0.5 MM TO 1.2 MM. DUCTAL CARCINOMA IN-SITU: NOT PRESENT. LOBULAR CARCINOMA IN-SITU: PRESENT. MARGINS: UNINVOLVED BY INVASIVE CARCINOMA. DISTANCE FROM CLOSEST MARGIN: <1 MM (MEDIAL). LYMPH NODES: SEE FULL DESCRIPTION UNDER SYNOPTIC REPORT #3. LYMPHOVASCULAR INVASION: NOT IDENTIFIED. PATHOLOGIC STAGING: mpT1a pNo(sn)(1-). ADDITIONAL PATHOLOGIC FINDINGS: INTRADUCTAL PAPILLOMA WITH FLORID DUCTAL HYPERPLASIA. FIBROCYSTIC CHANGE. ANCILLARY STUDIES: NOT PERFORMED ON CURRENT SPECIMEN. PERFORMED AND. PREVIOUSLY REPORTED ON BIOPSIES FROM OTHER LEFT BREAST SITES. SEE. SYNOPTIC REPORT #3. COLD ISCHEMIA TIME OF CURRENT SPECIMEN: 35 MINUTES. FORMALIN FIXATION TIME OF CURRENT SPECIMEN: 9 HOURS 41 MINUTES. SYNOPTIC REPORT #3 (LEFT BREAST LUMPECTOMIES X2 WITH SEPARATELY SUBMITTED MARGINS): PROCEDURE: EXCISIONS WITH WIRE GUIDED LOCALIZATION (2). LYMPH NODE SAMPLING: SENTINEL LYMPH NODES. SPECIMEN LATERALITY: LEFT. HISTOLOGIC TYPE OF INVASIVE CARCINOMA: INVASIVE LOBULAR CARCINOMA. TUMOR SIZE: SIZE OF LARGEST INVASIVE CARCINOMA AT LEAST 2.3 CM. IN GREATEST DIMENSION. HISTOLOGIC GRADE (NOTTINGHAM HISTOLOGIC SCORE): GLANDULAR/TUBULAR DIFFERENTIATION: SCORE 3. NUCLEAR PLEOMORPHISM: SCORE 1. MITOTIC RATE: SCORE 1. OVERALL GRADE: GRADE 1. TUMOR FOCALITY: MULTIPLE FOCI OF INVASIVE CARCINOMA. AT LEAST 7. SIZES OF INDIVIDUAL FOCI: RANGING FROM LESS THAN 0.5 MM TO AT LEAST 2.3 CM. DUCTAL CARCINOMA IN-SITU: NOT PRESENT. LOBULAR CARCINOMA IN-SITU: PRESENT. MARGINS: SEPARATELY SUBMITTED FINAL MARGINS UNINVOLVED BY INVASIVE CARCINOMA. DISTANCE FROM CLOSEST MARGIN: 3 MM FROM INFERIOR AND 9 MM FROM ANTERIOR. LYMPH NODES: NUMBER OF SENTINEL LYMPH NODES EXAMINED: 3. TOTAL NUMBER OF LYMPH NODES EXAMINED: 3. NUMBER OF LYMPH NODES WITH MACROMETASTASIS: 0. NUMBER OF LYMPH NODES WITH MICROMETASTASIS: 0. NUMBER OF LYMPH NODES WITH ISOLATED TUMOR CELLS: 0. NUMBER OF LYMPH NODES WITHOUT TUMOR CELLS IDENTIFIED: 3. METHOD OF EVALUATION OF SENTINEL LYMPH NODES: MULTIPLE H&E LEVELS AND. IMMUNOHISTOCHEMISTRY. LYMPHOVASCULAR INVASION: NOT IDENTIFIED. PATHOLOGIC STAGING: mpT2a pNo(sn)(I-). ADDITIONAL PATHOLOGIC FINDINGS: INTRADUCTAL PAPILLOMAS. FIBROCYSTIC CHANGE. FLORID DUCTAL HYPERPLASIA. FOCAL FIBROADENOMATOID CHANGE. ANCIL ARY STUDIES: AS PERFORMED AND PREVIOUSLY REPORTED (BIOPSIES FROM. FOR SITE #1 (SUSPICIOUS MASS 5 CM FROM NIPPLE): ESTROGEN RECEPTOR: POSITIVE (3+, 90%). PROGESTERONE RECEPTOR: POSITIVE (3+, 84%). HER-2: NEGATIVE (1+). FOR SITE #2 (10 O'CLOCK 7 - 8 CM FROM NIPPLE): ESTROGEN RECEPTOR: POSITIVE 3+, 95%. PROGESTERONE RECEPTOR: POSITIVE (3+, 77%). HER-2: NEGATIVE (0). COLD ISCHEMIA TIME OF CURRENT SPECIMEN: 13 MINUTES. FORMALIN FIXATION TIME OF CURRENT SPECIMEN: 9 HOURS 18 MINUTES. COMMENT: The case was discussed with the. on. The separately submitted margins are. oriented as being around both lumpectomy specimens within the Part L container. Consuitant: FROZEN SECTION DIAGNOSIS: B AND C. NEGATIVE LYMPH NODES. E, G, and H: MARGINS POSITIVE FOR INVASIVE LOBULAR CARCINOMA. F. MARGIN NEGATIVE FOR INVASIVE CARCINOMA: LCIS PRESENT. I and J: NEGATIVE FOR MALIGNANCY. K: NEGATIVE LYMPH NODE. M. POSITIVE FOR INVASIVE LOBULAR CARCINOMA. N. NEGATIVE FOR MALIGNANCY. O. POSITIVE FOR INVASIVE LOBULAR CARCINOMA. GROSS DESCRIPTION: A. Right breast umpectomy needle localized short double stitch, superior margin single long, lateral: Received fresh labaled. - right breast lumpectorny needle localization" and consists of oriented fragment of. fibrofatty tissue weighing 11 grams and measuring 4 x 3 x 2.5 cm. The specimen is oriented by two attached sutures. and is Inked as follows: superior - orange, lateral - yeliow, inferior - red, medial - green, anterior - blue, posterior -. biack. A localization needle extends from the lateral margin. The specimen is serially sectioned revealing abundant. dense fibrosis throughout with no grossly normal breast tissue appreciated. The dense fibrosis extends to within 0.1. cm. of all margina. No portion of the specimen is submitted for tissue banking due to the lack of discrete mass. The. specimen is entirely submitted A1) lateral margin, A2-A3) superior, inferior, anterior and posterior margins. A4). superior, anterior, posterior margin, A5) inferior, anterior, posterior margins, Aß) superior, inferior, anterior and. posterior margins. A7) inferior, superior and lateral margin. A8) medial and anterior margine. All margins are. perpendicular. The specimen has a coid ischemia time of 11 minutes. At the completion of processing the breast. tissue will have a formain fixation time of 10 hours and 33 minutes. B. Left breast sentinel node #1: Received fresh for frozen section evaluation labeled. left breast. sentinel lymph node" and consists of a single tan lymph node measuring 1.2 cm. in greatest dimension. The. specimen is entirely frazen in B-FS1 crybblock frozen section remnant as B1. C. Left breast sentinel node #2: Received fresh for frozen section evaluation labele. left breast. sentinel lymph node #2" and consists of a single fatty lymph node measuring 3 x 2.5 x 1 cm. The specimen is. bisected revealing fatty cut surfaces. The specimen is entirely frozen as C-FS1 - C-FS2 cryoblocks, frozen section. remnant as C1 - C2. D. Left breast needie localized subareolar biopsy - short double stitch superior, single long lateral margin: Received fresh labeled. Left breast needle localized subareolar biopsy" and consists of an oriented. fragment of fibrofatty tissue weighing 11 grams and measuring 7 x 3 x 2 cm. The specimen is oriented by two. attached sutures and is inked as follows: Superior orange, lateral yellow, inferior red, medial green, anterior blue,. posterior biack. A localization needle extends from the lateral margin. The specimen is serially sectioned, revealing. an lii-defined tan firm area measuring 0.5 cm in greatest dimension that lies 0.2 cm from the posterior margin at its. closest point. A representative portion of the mass is submitted for tissue banking. Within the same container are. two unoriented fragments of blue-tinged fibrofatty tissue, one weighing 3 grams and measuring 4.5 x 2x 1 cm, and. the second weighing 6 grams and measuring 6 x 4 x 0.6 cm. The smaller unoriented fragment is marked with orange. ink, and the larger unoriented fragment is marked with red ink. The unoriented fragments are serially sectioned,. revealing dense fibrosis and lobulated yellow adipose tisaue. Representative sections of the specimen are submitted. including the mass in its entirety. D1) Mass at closest point to posterior margin and tissue adjacent to portion of. specimen submitted for tissue banking. D2-D3) Tissue adjacent to mass including anterior, posterior, and lateral. margins. D4-D5) Dense fibrosis with anterior and posterior margina. D6) Dense fibrosis and inferior margin. D7). Dense fibrosis and superior margin. D8) Dense fibrosis with anterior and posterior margins. D9) Central transverse. smailer section, two fragments. D10) Central transverse larger unoriented fragment, two fragments. The specimen. has a coid ischamia start time of. and was received in pethology and immediately placed in formalin at. for a. cold ischemia time of 35 minutes. At the completion of processing, tissue will have been fixed in formalin for 9 hours. and 41 minutes. E. Left breast anterior margin stitch to mark tumor side: Received fresh for frozen section evaluation. labeled. Lumpectomy left anterior margin, stitch to tumor side", and consists of three oriented fatty tissue. fragment measuring 2x 1.5 x 0.5 cm, 2.5x 1.5x 1 cm and 2.2 x 1.6 x 0.6 cm. The tumor sides are designated by. attached sutures and the anterior margins are marked in blue Ink. Central transverse sections of the specimen are. frozen in EFS1 cryoblock, frozen section remnant as E1. F... Left breast superior margin stitch to mark tumor side: Received fresh for frozen section evaluation. Lumpectomy left superior margin, stitch to tumor side", and consists of an oriented fragment of fibrofatty. ussue measuring 3.5 x 2 x 1 cm. The tumor side is designated by an attached suture and the superior margin is. marked with orange Ink. A central transverse section of the specimen is frozen in FFS1 cryoblock, frozen section. remnant as F1. Left breest medial margin stitch to mark tumor side: Received fresh for frozen section evaluation. Lumpectomy left medial margin, stitch to tumor side", and consists of an oriented fragment of fibrofatty. tissue measuring 3.5 x 2 x 0.5 cm. The tumor side is designated by an attached suture and the medial margin is. marked with green ink. A central transverse section of the specimen is frozen in GFS1 cryoblock, frozen section. remnant as G1. H Left breast inferior margin stitch to mark tumor side: Received fresh for frozen section evaluation. - Lumpectomy left inferior margin, stitch to tumor side", and consists of an oriented fragment of fibrofatty. ussue. measuring. 2.5 x 2 x 1 cm. The tumor side is designated by an attached suture and the inferior margin is. marked with red ink. A central transverse section of the specimen is frozen in HFS1 cryoblock, frozen section. remnant as H1. Left breast lateral margin stitch to mark tumor side: Received fresh for frozen section evaluation. - Lumpectomy left lateral margin, stitch to tumor side", and consists of an oriented fragment of fibrofatty. ussue. measuring 3.1 x cm. The tumor side is designated by an attached suture and the laterai margin is. marked. with. yellow. ink. A central transverse section of the specimen is frozen in IFS1 cryoblock, frozen section. remnant as I1. J. Left breast posterior (deep) margin stitch to mark tumor side: Received fresh for frozen section. evaluation. - Lumpectomy left posterior margin, stitch to tumor side", and consists of an oriented fragment. of. fibrofatty. ussue. measuring 1.5 x 1.5 x 0,5 cm. The tumor side is designated by an attached suture and the. posterior margin is marked with black ink. A central transverse section of the specimen is frozen in JFS1 crybiock,. frozen section remnant as J1. K. Left breast, axiliary sentinel node #3: Received fresh for frozen section evaluation labeled. Axiliary sentinel lymph node #3, left breast", and consists of a fatty tan lymph node measuring 2 cm in greatest. dimension. The lymph node is bisected and entirely frozen in KFS1 cryoblock, frozen section remnant as K1. L. Left breast needle localized lumpectomy short double stitch, superior margin "single long, iaterai: Received fresh labeled. - Left breast needie localized lumpectomy" and consists of two oriented fragments. of fibrofatty tissue, each bearing localization clips. One lumpectorny fragment weighs 7 grams and measures 4.9 x 3.5: x 1 cm. The specimen is oriented by two. attached sutures and is Inked as follows: superior orange, lateral yellow, Inferior red, medial green, anterior purpie,. posterior black. The localization needie on this fragment extends from the anterior margin. This portion of the. specimen is serially sectioned revealing dense fibrosis with no discrete masses. No portion of this lumpectomy. is. submitted for tissue banking due to the lack of grosely appreciated abnormality. The second lumpectomy specimen weighs 18 grams and measures 6 x 4 x 2.5 cm. The specimen. is. oriented by two attached sutures and is inked as follows: superior orange, lateral yellow, inferior red, medial green,. anterior blue, posterior black. The localization needle on this lumpectomy specimen extends from the inferior margin. The specimen is serially sectioned revealing two H-defined masses, both bearing mammotome clips. The larger of. the two masses measures 1 x 1 x 0.9 cm and lies within 0.1 cm of both the posterior and inferior margins. Approximately 0.5 cm superior to this mass is an additional il-defined mass measuring 0.9 cm in greatest dimension. that lies 0.1 cm from the superior margin at its ciosest point. The remaining cut surfaces show lobulated, yellow. adipose tissue. A representative portion from each mass Is submitted for tissue banking. Representative sections of the specimen, including both masses in their entirety, are submitted. L1 medial. margin, first described lumpectomy. L2-L4 first described umpectomy, superior, anterior, inferior and posterior. margins. L5 first described iumpectomy, superior margin. L6 first described lumpectomy, lateral margin. L7 mass. at closest point to inferior margin. L8 inferior mass at inferior margin. L9 intervening tissue between inferior and. superior mass. L10 superior mass at closest point to superior margin. L11 superior mass. L12 tisaue adjacent. to. inferior mass. L13 anterior margin. L14 lateral margin. L15 medial margin. All margins are perpendicular. The specimen has a coid ischemia time of 13 minutes. At the completion of. processing, the breast tisaue will have a formain fixation time of 9 hours and 18 minutes. M. Left breast lumpectomy, new anterior margin stitch marks tumor side: Received fresh for frozen section. evaluation labeled. Left breast lumpectomy new anterior margin, stitch to tumor side", and consists of an. oriented fragment of fibrofatty tissue measuring 3 x 2.2: 0.5 cm. The tumor side is designated by an attached suture. and the new anterior margin is marked with blue ink. A central transverse section of the specimen is frozen in MFS1. cryoblock, frozen section remnant as M1. N. Left breast lumpectomy, new medial margin stitch marks tumor side: Received fresh for frozen section. evaluation labeled '. Left breast lumpectomy new medial margin, stitch marks tumor side", and consists of. an oriented fragment C. fibrofatty tissue measuring 2 x 2 x 0.5 cm. The tumor side is designated by an attached. suture and the new medial margin is marked with green ink. A central transverse section of the specimen is frozen in. NFS1 cryoblock, frozen section remnant as N1. O. Left breast iumpectomy, new inferior margin stitch marks tumor side: Received fresh for frozen section. evaluation labeled. Left breast lumpectomy new inferior margin, stitch marks tumor side", and consists of. an. oriented. fragment. of. fibrofatty tissue measuring 3 x 2x1 cm. The tumor side is designated by an attached suture. and the new inferior margin is marked with red ink A centrai transverse section of the specimen is frozen in OFS1. cryoblock, frozen section remnant as 01. P. Left breast lump additional anterior margin: Received fresh labeled. - Left breast lump. additional anterior margin", are two irreguiar, yellow, lobulated portions of fibroadipose tissue averaging 2.0x 1.8 x. 1.0. cm. Each tissue displays a stitch designating the tumor side. The margins are differentially Inked red and orange. and. representative sections are submitted in P1. Cold ischemia time. formalin fixation time. At the completion of processing, tissue will have been. fixed in formalin for 7 hours and 10 minutes. Q. Left breast lump additional inferior margin: Received fresh labeled. - Left breast lump. additional Inferior margin", are two irreguiar, yellow, lobulated portions of fibroadipose tissue averaging 20x 1.3 x 0.7. cm. Each tissue displays a stitch designating the tumor side. The margins are differentially inked yellow and green. and representative sections are submitted in Q1. Cold ischemia time. formalin fixation time. At the completion of processing, tissue will have been. fixed in formalin for 7 hours and 10 minutes. R. Left breast lumpectomy new superior margin: Received in formalin labeled. Left breast. lumpectomy, new superior margin, stitch tumor side", is a 2.6 x 2.5 x 0.8 cm irreguiar, yellow, lobulated portion of. fibroadipose tissue which displays e stitch designating the tumor side. The margin is inked red, and a representative. section is submitted in R1. Cold ischemia time. formalin fixation time. At the completion of processing, tissue will have. been fixed in formalin for 8 hours and 36 minutes. MICROSCOPIC DESCRIPTION: A. Sections from the entirely submitted specimen show a partially fragmented and cauterized intraductal. papilioma with florid hyperplasia. In the surrounding breast parenchyma there is fibrocystic change with florid. hyperplasia and papiliary apocrine change. A single focus of intermediate grade, solid type ductal carcinoma in situ. is present in A8 less than 1 mm to the green inked medial margin. invasive carcinoma is not identified. B. A single lymph node is negative for metastatic carcinoma. This is confirmed with a pancytokeratin. Immunohistochemical stain. An additional level is revlewed. C. A single sectioned lymph node is negative for metastatic carcinoma. This is confirmed with an. immunohistochemical stain for pancytokeratin. An additional level is reviewed. D. Sections reveal at least two foci of invasive lobular carcinoma with associated lobular carcinoma in situ. These foci are 1.2 mm and approximately 0.6 mm in greatest extent. The smaller focus lies approximately 0.5 mm. from the green inked medial margin. The 1.2 mm focus lies approximately 1 mm from the green Inked mediai margin. and black inked posterior margin. Additionally there in an intraductal papilioma with florid hyperplasia. Fibrocystic. change is seen. Previous blopsy site is identified. E. Sections of mammary parenchyma, which are Inked blue, show invasive lobular carcinoma. This. confirms the frozen section diagnosis. F. Portions of mammary parenchyma, which are inked orange, show a focus of lobular carcinoma in-situ. This confirms the frozen section diagnosia. G. A portion of mammary perenchyma, which is inked green, shows an area of Invasive lobular carcinoma. This is only seen on the frozen sections and not on the permanent section. H. Mammary parenchyma, which is inked red, shows invasive lobular carcinoma. This confirms the frozen. section diagnosis. I. Mammary parenchyma, which is inked yellow, shows fibrocystic changes. There is no atypia, in-situ. carcinoma, or Invasive carcinoma. This confirms the frozen section diagnosis. J. Mammary parenchyma with attached portion of skeletal muscle is inked black. There is no atypia, in-situ,. or invasive carcinoma. This confirms the frozen section diagnosia. K. A single bisected lymph node is negative for metastatic carcinoma. This is confirmed with a. pancytokeratin Immunohistochemical stain. An additional level is reviewed. L. Sections from the smaller oriented lumpectomy show multiple foci, at least four, of invasive lobular. carcinoma ranging in size from less than 1 mm up to 3 mm in size. invasive lobular carcinoma extends to the black. inked posterior margin and the orange inked superior margin. There is associated lobular carcinoma in-situ. The. second lumpectomy specimen also shows muitiple foci of Invasive lobular carcinama, with the largest focus. measuring at least 2.3 cm. in greatest dimension and spanning the area of both grossly identified masses. Additionally multiple foci of invasive lobular carcinoma are identified in the sections not from these masses. Invasive. foci measure from less than 1 mm up to the largest of at least 2.3 cm. Again, there is associated lobuiar carcinoma. in-situ. Biopsy site change is identified. Invasive lobular carcinoma extends to the red inked inferior margin and. age 7 of 7. blue inked anterior margin on the second lumpectomy specimen. Other benign changes seen include florld ductal. hyperplasia, intraductal paplilomas, fibrocystic change, and fibroadenomatoid change. No atypical ductal lesions. are. identified. No lymphovescuiar Invasion is identified. M. A portion of mammary parenchyma, which is inked blue, shows invasive lobular carcinoma. This. confirms the frozen section diagnosis. N. A portion of mammary parenchyma, which is Inked green, is negative for atypla or malignancy. This. confirms the frozen section diagnosis. O. A portion of mammary parenchyma, which is inked red, shows invasive lobular carcinoma. This. confirms the frozen section diagnosia. P. Portions of mammary parenchyma, which are inked orange and red, show a focus of invasive lobular. carcinoma lying 0.9 cm. from the orange Inked margin. Q. Portions of mammary perenchyma, which are inked yellow and green, show a focus of invasive lobular. carcinoma, 0.3 cm. from the yellow inked margin. R. A portion of mammary parenchyma, which is Inked red, is negative for atypia or maiignancy.

expanded version (tokens=6893) : 
 Histological classification: 
A. Right breast lumpectomy - Intermediate grade ductal carcinoma in situ (DCIS), solid type, measuring 2 mm in greatest extent. Intraductal papilloma with florid ductal hyperplasia and fibrocystic change identified.

B, C, K. Left breast sentinel nodes #1-3 - Negative for metastatic carcinoma (0/3).

D. Left breast subareolar lumpectomy - Multifocal invasive lobular carcinoma. Largest focus measures 1.2 mm in greatest extent. Intraductal papilloma with florid ductal hyperplasia and fibrocystic change identified.

E-J, L-R. Left breast lumpectomies - Multifocal invasive lobular carcinoma, largest focus measuring at least 2.3 cm in greatest dimension. Margins are negative, closest being 3 mm to inferior and 9 mm to anterior. Intraductal papillomas, florid ductal hyperplasia, and fibrocystic change are also present.

Histological grade: 
DCIS - Intermediate grade (G2)
Invasive lobular carcinoma - Overall grade 1

Nuclear grade: Glandular/tubular differentiation - Score 3, Nuclear pleomorphism - Score 1, Mitotic rate - Score 1

Lymphovascular invasion: Not identified

Calcification: Not mentioned in the report.

Receptor status:
Hormone

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=7032) : 
 Histological classification:
- Right breast: Intermediate grade ductal carcinoma in situ (DCIS), solid type
- Left breast: Multifocal invasive lobular carcinoma, largest focus measures at least 2.3 cm

Histological grade: DCIS - Intermediate grade, Invasive lobular carcinoma - Overall grade 1

Lymphovascular invasion: Not identified

Receptor status: Hormone receptor status not mentioned

Ancillary testing results: Not mentioned

