prompt1 : extract information from  breast pathology report. List the histological classification, i.e. type of cancer or DCIS, subtype, description of any necrosis, any mention of tumor infiltrating lymphocytes,  histological grade, nuclear grade,  lymphovascular invasion, calcification, receptor status, IHC and any other ancillary testing results.  List out and expand the main points.
prompt2 : The report is - Subtype LumB, ADDENDUM. Addendum #1. Entered: : BREAST CANCER PROGNOSTIC MARKERS. Specimen: Paraffin block 3A. Procedures: Paraffin Section Immunohistochemistry and DNA Flow Cytometry. ASSAYS: FAVORABLE. RANGES: Estrogen Receptors. Positive, 2-3+. Positive (1 -. 3+). Progesterone Receptors. Positive, 3+. Positive (1 -. Ploidy/DNA Index (DI). Aneuploid, DI=1.19, 2.01. Diploid, DI =. 1.0. S-Phase Fraction (%). Not Reported. Low (3% or. less). Ki-67 (Proliferation marker). High, 40-50%. Low (15% or. less). HER-2/neu (c-erb B2). Negative (0). Negative (0 -. 1+). p53. weakly Positive. Negative. S-phase fraction is not reported due to multiple aneuploid peaks. This immunoperoxidase test was developed and its performance characteristics. determined. by Although not cleared or approved by. the. U.S. Food and Drug Administration, the FDA has determined that such clearance or. approval. is not necessary. This test is used for clinical purposes and should not be. regarded. as investigational or for research. This laboratory is certified under the. Clinical. Laboratory Improvement Amendments of 1988 (CLIA) as qualified to perform high. complexity. clinical laboratory testing. Addendum Signed signature on file. GROSS DESCRIPTION. 1. Labeled "blue node, left axilla": The specimen consists of a bilobed blue dye. stained. apparent lymph node and fatty tissue. The fatty tissue is trimmed, revealing a. lymph node. that measures 1.6 x 1.0 x 0.4 cm. It is bisected and all embedded as 1A. Cytokeratin. stain. 2. Labeled "suspicious node, left axilla": The specimen consists of a tan yellow. firm. apparent lymph node that measures 1.0 x 0.5 x 0.3 cm. Bisected and all embedded as. 2A. 3. Labeled "segment, left breast, long stitch anterolateral, short stitch. anteromedial". The specimen consists of a blue dye stained piece of yellow tan tissue with. orienting. stitches. It measures 3.2 cm medial to lateral, 2.8 cm superior to inferior and. 4.4 cm in. depth. At the deep aspect of the tissue, there is a firm gritty tan nodule. The. specimen. is inked as follows: anterior - yellow, green - superior, black - lateral, blue -. inferior, red - medial, orange - deep. Sections through the tissue show a gritty. solid tan. mass at the deep lateral aspect of the specimen, measuring 2.0 x 2.0 X 1.7 cm. Representative tumor and normal tissue are provided for XXXX research studies (IRB#. XXXXXXXXXXXXXX). Multiple representative sections are embedded serially from. posterior. to anterior as 3A-G (tumor in blocks 3A-D). 4. Labeled "addition segment, left breast, no orientation": The specimen consists. of four. pieces of yellow tan hemorrhagic and blue dye stained tissue that measure in. aggregate. approximately 6.0 x 3.0 x 2.0 cm. The tissue is focally firm, but no definite. tumor is. identified grossly. Multiple representative sections are embedded as 4A-D, 4E-J -. additional firm areas of tissue. 5. Labeled "left breast lower quadrant mass" The specimen consists of three. pieces of. firm and soft tissue that measure in aggregate approximately 2.0 X 1.3 x 1.0 cm. One piece. represents a firm gray nodule, or portion thereof, measuring 1.4 X 0.8 C 0.2 cm. The. entire nodule and representative other tissue is embedded as 5A-B. 6. Labeled "inferior margin left breast": The specimen consists of a piece of. gray yellow. tissue that measures 2.3 X 1.0 x 0.3 cm. Embedded as 6A. 7. Labeled "superior margin left breast": The specimen consists of a piece of. blue dye. stained yellow tissue that measures 1.2 x 1.0 x 0.2 cm. Embedded as 7A. 8. Labeled "medial margin, left breast": The specimen consists of a piece of gray. yellow. tissue that measures 2.2 x 1.3 x 0.3 cm. Embedded as 8A. 9. Labeled "lateral margin, left breast": The specimen consists of a piece of. reddish. yellow and gray tissue that measures 1.5 x 0.6 X 0.2 cm. Embedded as 9A. 10. Labeled "anterior margin, left breast": The specimen consists of a piece of. gray. tissue that measures 1.6 X 0.6 x 0.2 cm. Embedded as 10A. 11. Labeled "deep margin, left breast": The specimen consists of a piece of yellow. red. tissue that measures 1.5 x 1.4 X 0.2 cm. Embedded as 11A. 12. Labeled "left breast lower quadrant skin": The specimen consists of a piece of. gray. pink tissue that measures 1.0 X 0.5 x 0.2 cm. Embedded as 12A. Microscopic H&E stained sections are prepared and interpreted. MICROSCOPIC. Sections show an infiltrating mammary carcinoma characterized by poor tubule. formation,. intermediate nuclear grade and high mitotic activity. The tumor cells infiltrate. as. sheets, single file, alveolar nests and occasional larger nests. The tumor has a. tendency. to infiltrate around existing ductal structures and focally formd targetoid lesions. around. this. Focal early necrosis is noted. There is a desmoplastic stromal response. IMMUNOCYTOCHEMISTRY RESULTS. Block 1A. Keratin: Negative. Block 3A. E-Cadherin: Negative. DIAGNOSIS. 1. SENTINEL LYMPH NODE, AXILLA, LEFT, BIOPSY: ONE LYMPH NODE, NEGATIVE FOR METASTATIC CARCINOMA BY H&E EXAMINATION. (0/1) . 2. LYMPH NODE, AXILLA, LEFT, BIOPSY: ONE LYMPH NODE, NEGATIVE FOR METASTATIC CARCINOMA (0/1). 3. BREAST, LEFT, SEGMENTECTOMY: INFILTRATING LOBULAR CARCINOMA, PLEOMORPHIC TYPE, POORLY DIFFERENTIATED,. 2.0 CM. NO IN SITU COMPONENT SEEN. NO DEFINITE LYMPHOVASCULAR INVASION IDENTIFIED. FOCAL BIOPSY RELATED CHANGES NOTED. TUMOR INVOLVES POSTERIOR, LATERAL AND SUPERIOR MARGINS (SEE ADDITIONAL. SEGMENT. AND SEPARATELY SUBMITTED MARGINS BELOW) . ADDITIONAL FINDINGS INCLUDE ATYPICAL LOBULAR HYPERPLASIA AND FIBROCYSTIC. CHANGE. MICROCALCIFICATIONS NOTED ASSOCIATED WITH BENIGN GLANDULAR ELEMENTS. 4. BREAST, LEFT, ADDITIONAL SEGMENT, SEGMENTECTOMY: ATYPICAL LOBULAR HYPERPLASIA. NO ADDITIONAL CARCINOMA SEEN. DDITIONAL FINDINGS INCLUDE FRADIAL SCAR FORMATION AND FIBROCYSTIC CHANGE. WITH. FIBROADENOMATOUS CHANGE. 5. BREAST, LEFT, LOWER QUADRANT, EXCISIONAL BIOPSY: CLUSTERED, CYSTICALLY DILATED DUCTS WITH PAPILLOMA FORMATION AND STROMAL. FIBROSIS, CONSISTENT WITH RADIAL SCAR. NEGATIVE FOR ATYPIA AND MALIGNANCY. 6. BREAST, LEFT, INFERIOR MARGIN, BIOPSY: BENIGN BREAST PARENCHYMA WITH RADIAL SCAR FORMATION. NEGATIVE FOR MALIGNANCY. 7. BREAST, LEFT, SUPERIOR MARGIN, BIOPSY: BENIGN BREAST PARENCHYMA. NEGATIVE FOR MALIGNANCY. 8. BREAST, LEFT, MEDIAL MARGIN, BIOPSY: BENIGN BREAST PARENCHYMA. NEGATIVE FOR MALIGNANCY. 9. BREAST, LEFT, LATERAL MARGIN, BIOPSY: BENIGN BREAST PARENCHYMA. NEGATIVE FOR MALIGNANCY. 10. BREAST, LEFT, ANTERIOR MARGIN, BIOPSY: BENIGN BREAST PARENCHYMA. NEGATIVE FOR MALIGNANCY. 11. BREAST, LEFT, DEEP MARGIN, BIOPSY: BENIGN SKELETAL MUSCLE AND FIBROADIPOSE TISSUE. NEGATIVE FOR MALIGNANCY. 12. SKIN, BREAST, LEFT, LOWER QUADRANT, BIOPSY: MINIMAL SUPERFICIAL PERIVASCULAR CHRONIC INFLAMMATION. NO INTRALYMPHATIC TUMOR SEEN. NEGATIVE FOR MALIGNANCY. BREAST CANCER PROGNOSTIC SUMMARY. SITE: LEFT BREAST 1-2 O'CLOCK. TUMOR SIZE: 2.0 CM. TUMOR TYPE: INFILTRATING LOBULAR CARCINOMA, PLEOMORPHIC TYPE. HISTOLOGIC GRADE: POORLY DIFFERENTIATED. MODIFIED BLOOM-. RICHARDSON SCORE: 8/9 (TUBULES 3, NUCLEI 2, MITOSES 3). IN SITU CARCINOMA: NOT PRESENT. TYPE: EXTENSIVE IN SITU. CARCINOMA: MARGINS OF RESECTION: POSTERIOR, LATERAL AND SUPERIOR SEGMENTS MARGINS OF. INITIAL. SEGMENT ARE POSITIVE. ADDITIONAL SEGMENTS AND SIX. SEPARATELY. SUBMITTED MARGIN BIOPSIES ARE NEGATIVE. NIPPLE/SKIN INVOLVEMENT: CANNOT ASSESS. LYMPHOVASCULAR INVASION: NOT IDENTIFIED. LYMPH NODES: NEGATIVE. # POSITIVE/TOTAL COUNT: 0/2. SENTINEL NODE: NEGATIVE (1). TNM PATHOLOGIC STAGE: : pT1c NO (sn) (i-) MX. MOLECULAR STUDIES: BLOCK 3A. signed Electronically signed by:

expanded version (tokens=2780) : 
 The pathology report describes the histological information of a breast cancer case. Here are the main points:

1. Histological classification: Infiltrating lobular carcinoma, pleomorphic type, poorly differentiated.
2. Receptor status: Estrogen receptor (ER) and progesterone receptor (PR) positive, HER-2/neu (c-erb B2) negative.
3. Ancillary testing: Proliferation marker Ki-67 high (40-50%), p53 weakly positive, diploid DNA index.
4. Necrosis: Focal early necrosis present.
5. Tumor infiltrating lymphocytes: Not mentioned in the report.
6. Histological grade: Poorly differentiated, modified Bloom-Richardson score 8/9 (tubules 3, nuclei 2, mitoses 3).
7. Lymphovascular invasion: Not identified.
8. Calcification: Microcalcifications noted associated with benign glandular elements.
9. Molecular studies: The report mentions a favorable result for molecular assays, such as Estrogen Receptors and Progesterone Receptors.
10. Margins of resection: Posterior, lateral, and superior margins of the initial segment were positive, while additional segments and six separately submitted margin biopsies were negative.
11. TNM pathologic stage: pT1c NO (sentinel node) (isolated tumor cells-) MX.
12. Additional findings: Atypical lobular hyper

prompt : Please generate a succinct report in 75 words from the above information. Exclude any filler words or sentences. If something is not mentioned or specified, exclude it from the report. Low verbosity.

final output (tokens=2957) : 
 Breast carcinoma is infiltrating lobular, pleomorphic subtype, poorly differentiated with early focal necrosis. ER/PR positive but HER-2/neu negative. Ki-67 proliferative index high (40-50%) and p53 weakly positive with diploid DNA index. No lymphovascular invasion identified. Margins of the resection are positive in initial segments while additional segments and six margin biopsies are negative. TNM pathologic stage is pT1c NO (sentinel node) (isolated tumor cells-) MX. Atypical lobular hyperplasia and microcalcifications noted with favorable molecular assay results.

