Networks for Joint Affine and Non-Parametric Image Registration

Zhengyang Shen, Xu Han, Zhenlin Xu, Marc Niethammer; Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2019, pp. 4224-4233


We introduce an end-to-end deep-learning framework for 3D medical image registration. In contrast to existing approaches, our framework combines two registration methods: an affine registration and a vector momentum-parameterized stationary velocity field (vSVF) model. Specifically, it consists of three stages. In the first stage, a multi-step affine network predicts affine transform parameters. In the second stage, we use a U-Net-like network to generate a momentum, from which a velocity field can be computed via smoothing. Finally, in the third stage, we employ a self-iterable map-based vSVF component to provide a non-parametric refinement based on the current estimate of the transformation map. Once the model is trained, a registration is completed in one forward pass. To evaluate the performance, we conducted longitudinal and cross-subject experiments on 3D magnetic resonance images (MRI) of the knee of the Osteoarthritis Initiative (OAI) dataset. Results show that our framework achieves comparable performance to state-of-the-art medical image registration approaches, but it is much faster, with a better control of transformation regularity including the ability to produce approximately symmetric transformations, and combining affine as well as non-parametric registration.

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[pdf] [supp]
author = {Shen, Zhengyang and Han, Xu and Xu, Zhenlin and Niethammer, Marc},
title = {Networks for Joint Affine and Non-Parametric Image Registration},
booktitle = {Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)},
month = {June},
year = {2019}