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0.99088 (h\055put) -189.98 (images) ] TJ T* [ (ar) 19.9928 (e) -311.991 (u) -1.01685 (s) 0.99221 (e) -1.00287 (d) -311.012 (in) -310.98 (ph) 1.00953 (ar) -8.0083 (ma) 1.01619 (col) -1.01219 (og) 1.02018 (y) -311.979 (and) -311.02 (basic) -311.011 (biol) -0.99887 (og) 1.02018 (y) -311.979 (to) -311.997 (g) 0.99088 (ener) 9.99672 (ate) ] TJ 11.9559 TL T* [ (an) 1.01486 (d) -423.994 (pr) -7.00876 (i) -0.98023 (or) -8.00564 (it) 1.00553 (i) -0.98023 (z) 5.9959 (e) -423.992 (h) 1.00553 (y) -0.99088 (p) 0.98289 (oth) 1.01885 (eses) -423.992 (w) -1.00953 (h) 1.00553 (ich) -423.982 (is) -424 (f) 0.98023 (u) -1.01752 (r) -7.01076 (th) 0.98822 (er) -424.015 (i) -0.98023 (n) 0.98822 (v) 4.97838 (estig) 1.0042 (ated) ] TJ 11.9551 TL T* [ (an) 1.01486 (d) -303 (v) 6.98212 (al) -1.01952 (idat) 1.00886 (ed) -302 (v) -0.98822 (ia) -302.01 (high) -302.018 (r) 20.0081 (esol) -0.98555 (ution) -302.011 (w) -1.00953 <69646502656c64> -301.985 (and) -301.985 (con) 0.98023 (foca) 0.99887 (l) ] TJ T* [ (micr) 6.98079 (o) -0.99355 (s) 0.99221 (cop) 25.0118 (y) -259.984 (imag) 0.98422 (e) -1.00287 (s) -258.981 (in) -258.985 (labs) 19.9788 (\056) -383.016 (B) 12.0051 (io) -0.99355 (logica) 0.98555 (l) -259.997 (specimen) 1.01219 (s) 9.98341 (\054) -269.011 (h) 1.00686 (avi) -1.0042 (n) 0.98822 (g) ] TJ T* [ (t) 1.00553 (hickn) 0.98023 (ess) -426.995 (an) 1.01486 (d) -425.997 (su) -1.00553 (r) -7.99232 (f) 0.98023 (ace) -426.006 (pr) 7.01209 (o) -0.99355 <02> 0.98023 (l) -1.0042 (es) -425.984 (consider) 10 (ably) -426.985 (l) -1.0042 (a) 1.00686 (r) 5.98791 (ger) -426.008 (th) 0.98822 (an) ] TJ 258.75 417.613 Td [ (t) 1.00686 (he) -297.987 (f) 0.98023 (ocu) -0.98289 (s) -296.998 (r) 9.01383 (a) 1.00686 (ng) 0.99887 (e) -298.013 (of) -298.003 (m) 0.98822 (i) -0.98023 (c) 0.98555 (r) 5.98791 (oscop) 1.01752 (e) -298.011 (l) -1.00154 (en) 1.00686 (ses) 10.0154 (\054) -316.017 (ar) 19.0132 (e) -298.011 (f) 0.98023 (r) 18.9866 (equ) -0.99088 (en) 1.00686 (tly) -298 (im\055) ] TJ T* [ (ag) 1.01752 (e) -1.0042 (d) -290 (as) -289.98 (3) -0.98555 (D) -290.984 (v) 4.97838 (olu) -1.01219 (mes) 19.9855 (\056) -476.99 (O) 7.01076 (pt) 1.00686 (i) -0.98023 (c) 0.98555 (al) -290.994 (sect) 1.00154 (i) -0.98023 (on) 1.01752 (i) -0.98023 (n) 0.98555 (g) -290.009 (o) -0.99088 (f) -290.02 (t) 1.00686 (he) -290.994 (sp) 0.99621 (ecimen) ] TJ T* [ (ca) 1.01219 (ptur) 19.0212 (es) -425.003 (th) 0.98822 (e) -425.997 (in\055f) 0.98289 (o) -0.99355 (c) 0.98555 (u) -1.01752 (s) -424.982 (inf) 0.98555 (o) -0.99088 (r) -7.01076 (mat) 1.00154 (i) -0.98023 (on) -424.998 (at) -424.982 (in) 0.98555 (cr) 18.9919 (eas) 0.99621 (i) -0.98023 (n) 0.98555 (g) -424.982 (dept) 1.00686 (hs) ] TJ T* [ (simu) -0.99621 (lat) 1.00953 (ing) -193.981 (an) -194.008 (exten) 0.98822 (ded) -195.009 (dep) 0.98023 (th) -193.989 (of) -194.016 <02656c> -0.98555 (d) 0.99621 (\056) -269.989 (A) -194.016 (3) -0.98555 (D) -195.007 (imag) 0.98555 (e) -195.001 (st) 1.01752 (ack) -194.985 (is) ] TJ T* [ (t) 1.00686 (hu) -0.99088 (s) -288.006 (a) -287.99 (seq) -0.98289 (uenc) 1.01752 (e) -289.021 (of) -287.987 (focused) -288.011 (i) -0.98023 (ma) 1.01752 (ge) -289.007 (s) 0.99088 (l) -1.00154 (ices) 10.01 (\054) -304.979 (which) -287.99 (c) 0.98555 (an) -287.979 (sub\055) ] TJ 11.9559 TL T* [ (sequ) -1.02018 (en) 1.00686 (tly) -364.013 (be) -362.988 (p) 0.98289 (r) 5.98791 (ocessed) -362.996 (t) 1.00686 (o) -362.993 (r) 18.9866 (econ) 1.00154 (str) -7.01609 (u) -1.01752 (c) 0.98555 (t) -362.999 (a) -362.999 (sin) 1.00154 (gle) -363.02 (al) -1.01752 (l\055dat) 0.98023 (a\055) ] TJ 11.9551 TL T* [ (in\055v) -0.98555 (iew) -377.995 (imag) 0.98555 (e) 18.9839 (\056) -737.006 (I) 19.0052 (n) -376.996 (bio\055) -0.98023 (imag) 0.98555 (e) -378.006 (a) 1.00686 (naly) -0.98023 (sis) 9.99406 (\054) -416 (2D) -378.016 (p) 0.98555 (r) 5.98791 (oje) -1.02285 (c) 0.98555 (tion) -376.983 (of) ] TJ T* [ (v) 4.97838 (olu) -1.01219 (me) -302.009 (i) -0.98023 (ma) 1.01752 (ges) -303.018 (a) 1.00686 (r) 18.9866 (e) -303 (r) 7.01076 (ou) -0.98822 (t) 1.00686 (i) -0.98023 (n) 0.98555 (el) -0.98555 (y) -302.986 (used) -303.002 (f) 0.98023 (or) -303.013 (dimensiona) 0.98555 (l) -1.00154 (it) 1.00686 (y) -304.009 (r) 20.0094 (e\055) ] TJ T* [ (duct) 0.99355 (i) -0.98023 (on) -356.979 (to) -357.983 (vi) -0.98822 (suali) -1.00154 (z) 5.9959 (e) -358.02 (a) 1.00686 (nd) -358.012 (an) 1.01752 (aly) -0.98555 (z) 5.99857 (e) -358.018 (v) 6.00389 (ar) -6.98412 (i) -0.98023 (ous) -357.991 (dat) 1.00686 (a) -358.012 (\133) ] TJ ET Q 0 1 0 rg q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 507.755 402.972 Tm (15) Tj ET Q 0 g q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 517.471 402.972 Tm [ (\135) -1.01752 (\056) -677.977 (The) ] TJ -208.609 -11.9551 Td [ (obje) -1.00154 (c) 0.98555 (tiv) 5.00502 (e) -309.989 (f) 0.98023 (or) -310 (a) -309.981 (2D) -309.994 (ap) 1.00953 (pr) 5.99058 (o) 18.9972 (ximation) -308.995 (of) -310.024 (t) 1.00686 (he) -308.979 (3) -0.98555 (D) -309.992 (v) 4.98105 (olu) -1.01219 (m) 0.99088 (e) -309.986 (i) -0.98023 (s) -309.017 (to) ] TJ 11.9547 TL T* [ (maximiz) 6.01988 (e) -376.005 (inf) 0.98822 (or) -8.0043 (mat) 0.99887 (i) -0.98023 (on) -375.006 (cont) 1.00686 (ent) -374.99 (maint) 1.00686 (ainin) 0.98023 (g) -376.013 (ac) 1.01219 (cu) -1.01219 (r) 9.99406 (ac) 1.01219 (y) -377.015 (of) ] TJ 11.9563 TL T* [ (man) 0.98023 (ifold) -309.003 (sh) 1.01752 (ape) -307.997 (and) -307.994 (simu) -0.99621 (lta) 1.00686 (neou) -1.00154 (sly) -309.006 (minimiz) -1.01219 (in) 0.98555 (g) -309.017 (t) 1.00686 (he) -308 (dis\055) ] TJ 11.9547 TL T* [ (t) 1.00686 (o) -0.99355 (r) -7.01076 (tion) -225.008 (of) -224.017 (P) 30.0195 (oint) -223.985 (S) 23.014 (p) 0.98289 (r) 18.9866 (ead) -225.002 (F) 11.9812 (u) -1.01752 (n) 0.98555 (ct) 1.01219 (i) -0.98023 (on) -224.009 (\050PSF) -0.99088 (\051) -225.01 (n) 0.98555 (oi) -0.99088 (se) -224.994 (an) 1.01752 (d) -225.01 (imag) 0.98555 (i) -0.98023 (n) 0.98555 (g) ] TJ T* [ (ar) -8.00697 (t) 1.00686 (ifac) 1.01219 (ts) 19.9828 (\056) ] TJ 11.9551 -23.093 Td [ (I) 19.0052 (n) -249.012 (t) 1.00686 (his) -248.983 (pap) 1.01486 (er) 58.9815 (\054) -254.99 (w) 5.97992 (e) -249.002 (u) -1.01752 (s) 0.99088 (e) -249.982 (t) 1.00686 (he) -249.015 (t) 1.00686 (er) -8.01762 (m) ] TJ /R21 9.1656 Tf 125.532 0 Td [ (compos) -1.01752 (ite) -249.985 (image) ] TJ /R19 9.1656 Tf 71.2848 0 Td [ (f) 0.98023 (o) -0.99088 (r) -249 (t) 1.00686 (he) ] TJ -208.772 -11.9551 Td [ (r) 18.9866 (ec) 1.0042 (o) 29.9902 (v) 4.97838 (er) 19.0052 (ed) -332.004 (2D) -331.986 (r) 18.9866 (epr) 19.9881 (esent) 0.98023 (ation) -331.994 (of) -330.992 (th) 0.99088 (e) -333 (3D) -331.988 (i) -0.98023 (m) 0.99088 (age) -331.983 (st) 1.01752 (ack) -332.004 (da) 0.98555 (ta) ] TJ T* [ (an) 1.01486 (d) ] TJ /R21 9.1656 Tf 18.2449 0 Td [ (in) -0.99088 (de) 9.99406 (x) -251.988 (map) ] TJ /R19 9.1656 Tf 46.2738 0 Td [ (f) 0.98023 (o) -0.99355 (r) -251.002 (th) 0.98822 (e) -251.985 (Z\055v) 5.99324 (alu) -1.01219 (es) -250.992 (on) -250.986 (th) 0.99088 (e) -251.982 (ma) 1.01752 (nifold) -252.014 (t) 1.00686 (o) -252.014 (r) 20.0094 (etain) ] TJ -64.5187 -11.9547 Td [ (dept) 1.0042 (h) -330.992 (in) 0.98822 (for) -8.0043 (ma) 1.01752 (tion\056) -596.983 (D) 11.0116 (ue) -330.992 (to) -331.008 (li) -1.00154 (mit) 1.01219 (ed) -330.981 (dept) 1.00686 (h) -330.992 (of) -330.012 <02656c> -0.98555 (d) -331.003 (of) -330.012 (mi\055) ] TJ 11.9563 TL T* [ (cr) 7.01342 (oscope) -268.015 (lenses) 41.0018 (\047) -267.986 (focus) 9.98341 (\054) -278.984 (th) 0.99088 (ese) -268.018 (met) 0.99088 (hods) -267.986 (w) 5.97726 (er) 19.9828 (e) -268.007 (i) -0.98023 (n) 0.98555 (itiall) -1.01752 (y) -267.996 (con) 0.98023 (\055) ] TJ 11.9551 TL T* [ (ceiv) 5.00236 (ed) -252.009 (for) -253.019 (b) 0.99887 (r) -7.99099 (ight) -251.005 <02656c> -0.98555 (d) -251.985 (li) -1.0042 (g) 0.99088 (ht) -251.993 (m) 0.99088 (i) -0.98023 (c) 0.98555 (r) 5.98791 (oscop) 25.0118 (y) -252.014 (\133) ] TJ ET Q 0 1 0 rg q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 474.815 260.327 Tm (1) Tj ET Q 0 g q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 479.673 260.327 Tm (\054) Tj ET Q 0 1 0 rg q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 484.42 260.327 Tm (14) Tj ET Q 0 g q 10 0 0 10 0 0 cm BT /R19 9.1656 Tf 1 0 0 1 494.145 260.327 Tm [ (\135\056) -362.002 (Th) 1.01219 (e) -253.005 (g) 0.99088 (r) 5.98791 (o) 29.9928 (w\055) ] TJ -185.283 -11.9547 Td [ (ing) -307.986 (pop) 1.01486 (u) -1.01752 (lar) -7.98832 (ity) -309.011 (of) -308.018 (3) -0.98555 (D) -307.989 (conf) 0.98023 (ocal) -308.99 (micr) 6.9788 (oscop) 25.0118 (y) -308.995 (h) 1.00686 (as) -308.99 (g) 0.99088 (ener) 10 (ated) ] TJ 11.9551 TL T* [ (n) 0.98822 (e) -1.0042 (w) -210.991 (deman) 1.02018 (ds) -211.018 (on) -211.01 (t) 1.00686 (r) 9.01383 (ad) 0.98289 (i) -0.98023 (t) 1.00686 (i) -0.98023 (on) 1.01752 (al) -211.98 (c) 0.98555 (omposite) -211.005 (imag) 0.98555 (e) -212.006 (g) 0.99088 (ener) 10 (ation) ] TJ T* [ (algor) -7.99099 (it) 1.00686 (hms) 19.9934 (\056) -263.002 (E) 6.01455 (x) 1.00154 (tr) 10.018 (act) 0.99621 (i) -0.98023 (on) -172.994 (of) -173.005 (th) 0.99088 (e) -173.99 (manif) 0.98023 (o) -0.99088 (ld) -172.994 (i) -0.98023 (n) -172.984 (a) -173.985 (3D) -174.001 (micr) 5.99857 (osc) 0.98555 (o) -0.99088 (p) 26.0027 (y) ] TJ T* [ (image) -220.016 (v) 4.97838 (olu) -1.01219 (me) -220.011 (con) 0.98023 (tainin) 1.00686 (g) -219.987 (th) 0.99088 (e) -220.999 (s) 0.99088 (pecimen) -220.019 (of) -220.013 (int) 1.01219 (er) 19.0026 (est) -219.981 (b) 0.99621 (egins) ] TJ 11.9559 TL T* [ (wi) -1.00953 (t) 1.00686 (h) -171.982 (acqu) -1.02018 (isition) -172.019 (of) -173.002 (a) 1.00686 (n) -172.981 (ext) 1.00154 (ended) -172.009 (dept) 1.00686 (h) -171.982 (o) -0.99088 (f) -172.009 <02> 0.98023 (e) -1.00154 (ld) -172.014 (i) -0.98023 (ma) 1.01752 (ge) -173 (st) 1.01752 (ack) 1.01752 (\056) ] TJ 11.9551 TL T* [ (W) 64.9987 (e) -326.994 (app) 1.01486 (l) -1.0042 (y) -326.981 (an) -325.998 (o) -0.99355 (p) 0.98289 (er) 8.98986 (a) 1.00686 (tor) 59.9963 (\054) -353.013 (for) -327.007 (examp) 1.01752 (l) -1.00154 (e) -326.991 (in) 0.98555 (tens) 1.00154 (i) -0.98023 (t) 1.00686 (y) -328.003 (ma) 1.01752 (xi) -1.00154 (m) 0.99088 (a\054) -352.983 (in) ] TJ T* [ (ca) 1.01219 (se) -291.01 (of) -289.01 (M) 12.0158 (ax) 0.98555 (i) -0.98023 (mum) -289.996 (I) 19.0052 (nt) 1.01219 (ensity) -290.009 (P) 11.9918 (r) 5.98791 (oje) -1.02285 (c) 0.98555 (tion) -289.998 (\050M) 0.99621 (IP\051) -289.993 (on) -289.982 (eac) 0.99088 (h) -289.993 (2D) ] TJ T* [ (image) -330.995 (sl) -0.99355 (ic) 0.98555 (e) 18.9839 (\056) -599.987 (T) 0.98555 (he) -331.996 (p) 0.98289 (l) -1.0042 (a) 1.00686 (ne) -332.015 (ind) 1.00686 (ex) -332.004 (of) -330.992 (maxima) -331.994 (of) -330.992 (int) 1.01219 (ensit) 1.00154 (y) -332.99 (r) 20.0094 (e\055) ] TJ T* [ (sp) 0.99621 (o) -0.99355 (n) 0.98822 (se) -304.009 (for) -303.99 (eac) 0.98822 (h) -304.014 (p) 0.98289 (i) -0.98023 (xel) -303.982 (position) -302.997 (al) -1.01752 (on) 1.01752 (g) -303.988 (z\055) -1.00154 (a) 1.00686 (xi) 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