A Unified Model for Compressed Sensing MRI Across Undersampling Patterns

Armeet Singh Jatyani, Jiayun Wang, Aditi Chandrashekar, Zihui Wu, Miguel Liu-Schiaffini, Bahareh Tolooshams, Anima Anandkumar; Proceedings of the Computer Vision and Pattern Recognition Conference (CVPR), 2025, pp. 26004-26013

Compressed Sensing MRI reconstructs images of the body's internal anatomy from undersampled measurements, thereby reducing the scan time - the time subjects need to remain still. Recently, deep learning has shown great potential for reconstructing high-fidelity images from highly undersampled measurements. However, one needs to train multiple models for different undersampling patterns and desired output image resolutions, since most networks operate on a fixed discretization. Such approaches are highly impractical in clinical settings, where undersampling patterns and image resolutions are frequently changed to accommodate different real-time imaging and diagnostic requirements. We propose a unified MRI reconstruction model robust to various measurement undersampling patterns and image resolutions. Our approach uses neural operators- a discretization-agnostic architecture applied in both image and measurement spaces--to capture local and global features. Empirically, our model improves SSIM by 11% and PSNR by 4dB over a state-of-the-art CNN (End-to-End VarNet), with inference 600x faster than diffusion methods. The resolution-agnostic design also enables zero-shot super-resolution and extended field-of-view reconstruction, offering a versatile and efficient solution for clinical MR imaging. Our unified model offers a versatile solution for MRI, adapting seamlessly to various measurement undersampling and imaging resolutions, making it highly effective for flexible and reliable clinical imaging. Our code is available at https://armeet.ca/nomri.